Phosphorylation of Shc by Src family kinases is necessary for stem cell factor receptor/c-kit mediated activation of the Ras/MAP kinase pathway and c-fos induction

Oncogene

Volumn 18, Issue 40, 1999, Pages 5546-5553

  Lennartsson, Johan ^a   Blume Jensen, Peter ^a,b   Hermanson, Monica ^a   Pontén, Emma ^a   Carlberg, Monika ^a   Rönnstrand, Lars ^a  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (Sweden)

^b SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

Author keywords

c kit; MAP kinase; Mitogenicity; Ras; Shc; Src

Indexed keywords

ADAPTOR PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHENYLALANINE; PROTEIN TYROSINE KINASE; STEM CELL FACTOR RECEPTOR; TYROSINE;

ANIMAL CELL; AORTA; ARTICLE; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE INDUCTION; MITOGENESIS; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; AORTA; CELL DIVISION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENES, FOS; HUMANS; LIGANDS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; PROTO-ONCOGENE PROTEINS C-KIT; PROTO-ONCOGENE PROTEINS P21(RAS); RECOMBINANT FUSION PROTEINS; SRC-FAMILY KINASES; STEM CELL FACTOR; SWINE;

ANIMALIA; SUIDAE;

EID: 0033619142     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202929     Document Type: Article

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