Glutathione redox regulates TGF-β-induced fibrogenic effects through Smad3 activation

FEBS Letters

Volumn 583, Issue 2, 2009, Pages 357-362

  Ono, Akihiro ^a   Utsugi, Mitsuyoshi ^a   Masubuchi, Ken ^a   Ishizuka, Tamotsu ^a   Kawata, Tadayoshi ^a   Shimizu, Yasuo ^a   Hisada, Takeshi ^a   Hamuro, Junji ^b   Mori, Masatomo ^a   Dobashi, Kunio ^c  

^a GUNMA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c GUNMA UNIVERSITY   (Japan)

Author keywords

Bronchial smooth muscle cell; Fibrogenic effect; Glutathione redox; Human lung fibroblast; Smad; Transforming growth factor

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; FIBRONECTIN; GLUTATHIONE; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; BRONCHUS MUSCLE; CELL TRANSFORMATION; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FIBROGENESIS; HUMAN; HUMAN CELL; LUNG FIBROBLAST; MYOFIBROBLAST; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACTINS; CELL LINE; COLLAGEN TYPE I; CONNECTIVE TISSUE GROWTH FACTOR; DEXAMETHASONE; FIBROBLASTS; FIBRONECTINS; GLUTATHIONE; HUMANS; MYOBLASTS; PHOSPHORYLATION; PULMONARY FIBROSIS; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 58149527800     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.12.021     Document Type: Article

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