SUMOylation of human peroxisome proliferator-activated receptor α inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR

Journal of Biological Chemistry

Volumn 285, Issue 9, 2010, Pages 5983-5992

  Pourcet, Benoit ^a,b,c   Pineda Torra, Inés ^d   Derudas, Bruno ^a,b,c   Staels, Bart ^a,b,c   Glineur, Corine ^a,b,c  

^a UNIV LILLE   (France)

^b INSERM   (France)

^c INSTITUT PASTEUR DE LILLE   (France)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; GENE EXPRESSION; LIGANDS;

KEY REGULATORS; LIGAND BINDING; LIPID HOMEOSTASIS; NUCLEAR RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; POST-TRANSLATIONAL MODIFICATIONS; SELECTIVE RECRUITMENT; UBIQUITINATION;

CYTOLOGY;

LYSINE; NUCLEAR RECEPTOR COREPRESSOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PROTEIN UBC9; SUMO 1 PROTEIN; COREPRESSOR PROTEIN; NCOR1 PROTEIN, HUMAN; RECEPTOR INTERACTING PROTEIN 140; SUMO1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INTERACTION; PROTEIN MODIFICATION; SITE DIRECTED MUTAGENESIS; SUMOYLATION; TRANSACTIVATION; UBIQUITINATION; BINDING SITE; CELL LINE; KINETICS; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT;

BINDING SITES; CELL LINE; CO-REPRESSOR PROTEINS; GENE EXPRESSION REGULATION; HUMANS; KINETICS; LYSINE; NUCLEAR RECEPTOR CO-REPRESSOR 1; PPAR ALPHA; PROTEIN TRANSPORT; SUMO-1 PROTEIN;

EID: 77949878458     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.078311     Document Type: Article

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