메뉴 건너뛰기




Volumn 6, Issue 9, 2011, Pages

Targeting KSHV/HHV-8 latency with COX-2 selective inhibitor nimesulide: A potential chemotherapeutic modality for primary effusion lymphoma

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CYCLIN A; CYCLIN E; CYCLOOXYGENASE 2; GLYCOGEN SYNTHASE KINASE 3BETA; HYBRID PROTEIN; NIMESULIDE; PROTEIN CDC25C; PROTEIN KINASE B; PROTEIN P21; PROTEIN P53; PROTEIN P53 LANA 1 PROTEIN FUSION PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN C; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2 INHIBITOR; SULFONAMIDE; TP53 PROTEIN, HUMAN;

EID: 80053583190     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024379     Document Type: Article
Times cited : (39)

References (53)
  • 2
    • 33645744610 scopus 로고    scopus 로고
    • KSHV infection and the pathogenesis of Kaposi's sarcoma
    • Ganem D, (2006) KSHV infection and the pathogenesis of Kaposi's sarcoma. Annu Rev Pathol 1: 273-296.
    • (2006) Annu Rev Pathol , vol.1 , pp. 273-296
    • Ganem, D.1
  • 3
    • 24044496609 scopus 로고    scopus 로고
    • Targeting human herpesvirus-8 for treatment of Kaposi's sarcoma and primary effusion lymphoma
    • Klass CM, Offermann MK, (2005) Targeting human herpesvirus-8 for treatment of Kaposi's sarcoma and primary effusion lymphoma. Curr Opin Oncol 17: 447-455.
    • (2005) Curr Opin Oncol , vol.17 , pp. 447-455
    • Klass, C.M.1    Offermann, M.K.2
  • 4
    • 14644419026 scopus 로고    scopus 로고
    • Glycyrrhizic acid alters Kaposi sarcoma-associated herpesvirus latency, triggering p53-mediated apoptosis in transformed B lymphocytes
    • Curreli F, Friedman-Kien AE, Flore O, (2005) Glycyrrhizic acid alters Kaposi sarcoma-associated herpesvirus latency, triggering p53-mediated apoptosis in transformed B lymphocytes. J Clin Invest 115: 642-652.
    • (2005) J Clin Invest , vol.115 , pp. 642-652
    • Curreli, F.1    Friedman-Kien, A.E.2    Flore, O.3
  • 5
    • 6344265692 scopus 로고    scopus 로고
    • Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas
    • An J, Sun Y, Fisher M, Rettig MB, (2004) Antitumor effects of bortezomib (PS-341) on primary effusion lymphomas. Leukemia 18: 1699-1704.
    • (2004) Leukemia , vol.18 , pp. 1699-1704
    • An, J.1    Sun, Y.2    Fisher, M.3    Rettig, M.B.4
  • 6
    • 0035950522 scopus 로고    scopus 로고
    • Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma
    • Toomey NL, Deyev VV, Wood C, Boise LH, Scott D, et al. (2001) Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma. Oncogene 20: 7029-7040.
    • (2001) Oncogene , vol.20 , pp. 7029-7040
    • Toomey, N.L.1    Deyev, V.V.2    Wood, C.3    Boise, L.H.4    Scott, D.5
  • 7
    • 33847390842 scopus 로고    scopus 로고
    • Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling
    • Sin SH, Roy D, Wang L, Staudt MR, Fakhari FD, et al. (2007) Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling. Blood 109: 2165-2173.
    • (2007) Blood , vol.109 , pp. 2165-2173
    • Sin, S.H.1    Roy, D.2    Wang, L.3    Staudt, M.R.4    Fakhari, F.D.5
  • 8
    • 34147158893 scopus 로고    scopus 로고
    • Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas
    • Sarek G, Kurki S, Enback J, Iotzova G, Haas J, et al. (2007) Reactivation of the p53 pathway as a treatment modality for KSHV-induced lymphomas. J Clin Invest 117: 1019-1028.
    • (2007) J Clin Invest , vol.117 , pp. 1019-1028
    • Sarek, G.1    Kurki, S.2    Enback, J.3    Iotzova, G.4    Haas, J.5
  • 9
    • 0035951459 scopus 로고    scopus 로고
    • Long-term remission of an AIDS-related primary effusion lymphoma with antiviral therapy
    • Hocqueloux L, Agbalika F, Oksenhendler E, Molina JM, (2001) Long-term remission of an AIDS-related primary effusion lymphoma with antiviral therapy. Aids 15: 280-282.
    • (2001) Aids , vol.15 , pp. 280-282
    • Hocqueloux, L.1    Agbalika, F.2    Oksenhendler, E.3    Molina, J.M.4
  • 10
    • 20144380289 scopus 로고    scopus 로고
    • Treatment of herpesvirus associated primary effusion lymphoma with intracavity cidofovir
    • Luppi M, Trovato R, Barozzi P, Vallisa D, Rossi G, et al. (2005) Treatment of herpesvirus associated primary effusion lymphoma with intracavity cidofovir. Leukemia 19: 473-476.
    • (2005) Leukemia , vol.19 , pp. 473-476
    • Luppi, M.1    Trovato, R.2    Barozzi, P.3    Vallisa, D.4    Rossi, G.5
  • 11
    • 33845353262 scopus 로고    scopus 로고
    • A non-chemotherapy treatment of a primary effusion lymphoma: durable remission after intracavitary cidofovir in HIV negative PEL refractory to chemotherapy
    • Halfdanarson TR, Markovic SN, Kalokhe U, Luppi M, (2006) A non-chemotherapy treatment of a primary effusion lymphoma: durable remission after intracavitary cidofovir in HIV negative PEL refractory to chemotherapy. Ann Oncol 17: 1849-1850.
    • (2006) Ann Oncol , vol.17 , pp. 1849-1850
    • Halfdanarson, T.R.1    Markovic, S.N.2    Kalokhe, U.3    Luppi, M.4
  • 12
    • 77953932867 scopus 로고    scopus 로고
    • Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas
    • Bhatt AP, Bhende PM, Sin SH, Roy D, Dittmer DP, et al. (2010) Dual inhibition of PI3K and mTOR inhibits autocrine and paracrine proliferative loops in PI3K/Akt/mTOR-addicted lymphomas. Blood 115: 4455-4463.
    • (2010) Blood , vol.115 , pp. 4455-4463
    • Bhatt, A.P.1    Bhende, P.M.2    Sin, S.H.3    Roy, D.4    Dittmer, D.P.5
  • 13
    • 29244449354 scopus 로고    scopus 로고
    • Prostaglandins and cancer
    • Wang D, Dubois RN, (2006) Prostaglandins and cancer. Gut 55: 115-122.
    • (2006) Gut , vol.55 , pp. 115-122
    • Wang, D.1    Dubois, R.N.2
  • 14
    • 65349152488 scopus 로고    scopus 로고
    • Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement
    • Cuzick J, Otto F, Baron JA, Brown PH, Burn J, et al. (2009) Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement. Lancet Oncol 10: 501-507.
    • (2009) Lancet Oncol , vol.10 , pp. 501-507
    • Cuzick, J.1    Otto, F.2    Baron, J.A.3    Brown, P.H.4    Burn, J.5
  • 15
    • 0035185156 scopus 로고    scopus 로고
    • COX-2 and cancer: a new approach to an old problem
    • Bakhle YS, (2001) COX-2 and cancer: a new approach to an old problem. Br J Pharmacol 134: 1137-1150.
    • (2001) Br J Pharmacol , vol.134 , pp. 1137-1150
    • Bakhle, Y.S.1
  • 16
    • 35348913142 scopus 로고    scopus 로고
    • Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1
    • de Groot DJ, van der Deen M, Le TK, Regeling A, de Jong S, et al. (2007) Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1. Br J Cancer 97: 1077-1083.
    • (2007) Br J Cancer , vol.97 , pp. 1077-1083
    • de Groot, D.J.1    van der Deen, M.2    Le, T.K.3    Regeling, A.4    de Jong, S.5
  • 17
    • 73249137348 scopus 로고    scopus 로고
    • Chemopreventive response of diclofenac, a non-steroidal anti-inflammatory drug in experimental carcinogenesis
    • Kaur Saini M, Kaur J, Sharma P, Nath Sanyal S, (2009) Chemopreventive response of diclofenac, a non-steroidal anti-inflammatory drug in experimental carcinogenesis. Nutr Hosp 24: 717-723.
    • (2009) Nutr Hosp , vol.24 , pp. 717-723
    • Kaur Saini, M.1    Kaur, J.2    Sharma, P.3    Nath Sanyal, S.4
  • 18
    • 60549114558 scopus 로고    scopus 로고
    • NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2
    • Liu JF, Zhu GJ, Jamieson GG, Wu TC, Zhu TN, et al. (2009) NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2. Cancer Invest 27: 17-23.
    • (2009) Cancer Invest , vol.27 , pp. 17-23
    • Liu, J.F.1    Zhu, G.J.2    Jamieson, G.G.3    Wu, T.C.4    Zhu, T.N.5
  • 20
    • 27644555091 scopus 로고    scopus 로고
    • Cyclooxygenase-2: how good is it as a target for cancer chemoprevention?
    • Hull MA, (2005) Cyclooxygenase-2: how good is it as a target for cancer chemoprevention? Eur J Cancer 41: 1854-1863.
    • (2005) Eur J Cancer , vol.41 , pp. 1854-1863
    • Hull, M.A.1
  • 21
    • 38049144569 scopus 로고    scopus 로고
    • Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt
    • Sinha-Datta U, Taylor JM, Brown M, Nicot C, (2008) Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt. Apoptosis 13: 33-40.
    • (2008) Apoptosis , vol.13 , pp. 33-40
    • Sinha-Datta, U.1    Taylor, J.M.2    Brown, M.3    Nicot, C.4
  • 23
    • 20444422917 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) is frequently expressed in multiple myeloma and is an independent predictor of poor outcome
    • Ladetto M, Vallet S, Trojan A, Dell'Aquila M, Monitillo L, et al. (2005) Cyclooxygenase-2 (COX-2) is frequently expressed in multiple myeloma and is an independent predictor of poor outcome. Blood 105: 4784-4791.
    • (2005) Blood , vol.105 , pp. 4784-4791
    • Ladetto, M.1    Vallet, S.2    Trojan, A.3    Dell'Aquila, M.4    Monitillo, L.5
  • 24
    • 52949102543 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 in hematological malignancies: rationale and promise
    • Bernard MP, Bancos S, Sime PJ, Phipps RP, (2008) Targeting cyclooxygenase-2 in hematological malignancies: rationale and promise. Curr Pharm Des 14: 2051-2060.
    • (2008) Curr Pharm Des , vol.14 , pp. 2051-2060
    • Bernard, M.P.1    Bancos, S.2    Sime, P.J.3    Phipps, R.P.4
  • 25
    • 1642453832 scopus 로고    scopus 로고
    • Host gene induction and transcriptional reprogramming in Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8)-infected endothelial, fibroblast, and B cells: insights into modulation events early during infection
    • Naranatt PP, Krishnan HH, Svojanovsky SR, Bloomer C, Mathur S, et al. (2004) Host gene induction and transcriptional reprogramming in Kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8)-infected endothelial, fibroblast, and B cells: insights into modulation events early during infection. Cancer Res 64: 72-84.
    • (2004) Cancer Res , vol.64 , pp. 72-84
    • Naranatt, P.P.1    Krishnan, H.H.2    Svojanovsky, S.R.3    Bloomer, C.4    Mathur, S.5
  • 26
    • 77951722799 scopus 로고    scopus 로고
    • Piracy of prostaglandin E2/EP receptor-mediated signaling by Kaposi's sarcoma-associated herpes virus (HHV-8) for latency gene expression: strategy of a successful pathogen
    • George Paul A, Sharma-Walia N, Kerur N, White C, Chandran B, (2010) Piracy of prostaglandin E2/EP receptor-mediated signaling by Kaposi's sarcoma-associated herpes virus (HHV-8) for latency gene expression: strategy of a successful pathogen. Cancer Res 70: 3697-3708.
    • (2010) Cancer Res , vol.70 , pp. 3697-3708
    • George Paul, A.1    Sharma-Walia, N.2    Kerur, N.3    White, C.4    Chandran, B.5
  • 27
    • 34247119790 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expression
    • Sadagopan S, Sharma-Walia N, Veettil MV, Raghu H, Sivakumar R, et al. (2007) Kaposi's sarcoma-associated herpesvirus induces sustained NF-kappaB activation during de novo infection of primary human dermal microvascular endothelial cells that is essential for viral gene expression. J Virol 81: 3949-3968.
    • (2007) J Virol , vol.81 , pp. 3949-3968
    • Sadagopan, S.1    Sharma-Walia, N.2    Veettil, M.V.3    Raghu, H.4    Sivakumar, R.5
  • 28
    • 77649258068 scopus 로고    scopus 로고
    • Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion
    • Sharma-Walia N, Paul AG, Bottero V, Sadagopan S, Veettil MV, et al. (2010) Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion. PLoS Pathog 6: e1000777.
    • (2010) PLoS Pathog , vol.6
    • Sharma-Walia, N.1    Paul, A.G.2    Bottero, V.3    Sadagopan, S.4    Veettil, M.V.5
  • 29
    • 33745286003 scopus 로고    scopus 로고
    • Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expression
    • Sharma-Walia N, Raghu H, Sadagopan S, Sivakumar R, Veettil MV, et al. (2006) Cyclooxygenase 2 induced by Kaposi's sarcoma-associated herpesvirus early during in vitro infection of target cells plays a role in the maintenance of latent viral gene expression. J Virol 80: 6534-6552.
    • (2006) J Virol , vol.80 , pp. 6534-6552
    • Sharma-Walia, N.1    Raghu, H.2    Sadagopan, S.3    Sivakumar, R.4    Veettil, M.V.5
  • 30
    • 0037841849 scopus 로고    scopus 로고
    • Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line
    • Li JY, Wang XZ, Chen FL, Yu JP, Luo HS, (2003) Nimesulide inhibits proliferation via induction of apoptosis and cell cycle arrest in human gastric adenocarcinoma cell line. World J Gastroenterol 9: 915-920.
    • (2003) World J Gastroenterol , vol.9 , pp. 915-920
    • Li, J.Y.1    Wang, X.Z.2    Chen, F.L.3    Yu, J.P.4    Luo, H.S.5
  • 31
    • 0028122558 scopus 로고
    • Nimesulide. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy
    • Davis R, Brogden RN, (1994) Nimesulide. An update of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs 48: 431-454.
    • (1994) Drugs , vol.48 , pp. 431-454
    • Davis, R.1    Brogden, R.N.2
  • 32
    • 34548083312 scopus 로고    scopus 로고
    • Development of a fluorescence-based assay to screen antiviral drugs against Kaposi's sarcoma associated herpesvirus
    • Nun TK, Kroll DJ, Oberlies NH, Soejarto DD, Case RJ, et al. (2007) Development of a fluorescence-based assay to screen antiviral drugs against Kaposi's sarcoma associated herpesvirus. Mol Cancer Ther 6: 2360-2370.
    • (2007) Mol Cancer Ther , vol.6 , pp. 2360-2370
    • Nun, T.K.1    Kroll, D.J.2    Oberlies, N.H.3    Soejarto, D.D.4    Case, R.J.5
  • 33
    • 77950503703 scopus 로고    scopus 로고
    • Distinct p53, p53:LANA, and LANA complexes in Kaposi's Sarcoma-associated Herpesvirus Lymphomas
    • Chen W, Hilton IB, Staudt MR, Burd CE, Dittmer DP, (2010) Distinct p53, p53:LANA, and LANA complexes in Kaposi's Sarcoma-associated Herpesvirus Lymphomas. J Virol 84: 3898-3908.
    • (2010) J Virol , vol.84 , pp. 3898-3908
    • Chen, W.1    Hilton, I.B.2    Staudt, M.R.3    Burd, C.E.4    Dittmer, D.P.5
  • 34
    • 71749090881 scopus 로고    scopus 로고
    • Lead optimization of COX-2 inhibitor nimesulide analogs to overcome aromatase inhibitor resistance in breast cancer cells
    • Su B, Chen S, (2009) Lead optimization of COX-2 inhibitor nimesulide analogs to overcome aromatase inhibitor resistance in breast cancer cells. Bioorg Med Chem Lett 19: 6733-6735.
    • (2009) Bioorg Med Chem Lett , vol.19 , pp. 6733-6735
    • Su, B.1    Chen, S.2
  • 35
    • 76849087997 scopus 로고    scopus 로고
    • Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis
    • Wen KW, Damania B, (2010) Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis. Cancer Lett 289: 140-150.
    • (2010) Cancer Lett , vol.289 , pp. 140-150
    • Wen, K.W.1    Damania, B.2
  • 36
    • 0037348372 scopus 로고    scopus 로고
    • A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency
    • Fujimuro M, Wu FY, ApRhys C, Kajumbula H, Young DB, et al. (2003) A novel viral mechanism for dysregulation of beta-catenin in Kaposi's sarcoma-associated herpesvirus latency. Nat Med 9: 300-306.
    • (2003) Nat Med , vol.9 , pp. 300-306
    • Fujimuro, M.1    Wu, F.Y.2    ApRhys, C.3    Kajumbula, H.4    Young, D.B.5
  • 37
    • 28544444039 scopus 로고    scopus 로고
    • Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis
    • Castellone MD, Teramoto H, Williams BO, Druey KM, Gutkind JS, (2005) Prostaglandin E2 promotes colon cancer cell growth through a Gs-axin-beta-catenin signaling axis. Science 310: 1504-1510.
    • (2005) Science , vol.310 , pp. 1504-1510
    • Castellone, M.D.1    Teramoto, H.2    Williams, B.O.3    Druey, K.M.4    Gutkind, J.S.5
  • 38
    • 0032750920 scopus 로고    scopus 로고
    • Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing
    • Jones MK, Wang H, Peskar BM, Levin E, Itani RM, et al. (1999) Inhibition of angiogenesis by nonsteroidal anti-inflammatory drugs: insight into mechanisms and implications for cancer growth and ulcer healing. Nat Med 5: 1418-1423.
    • (1999) Nat Med , vol.5 , pp. 1418-1423
    • Jones, M.K.1    Wang, H.2    Peskar, B.M.3    Levin, E.4    Itani, R.M.5
  • 39
    • 0034961293 scopus 로고    scopus 로고
    • Effects of vascular endothelial growth factor and E-selectin on angiogenesis in the murine metastatic RCT sarcoma
    • Aoki M, Kanamori M, Yudoh K, Ohmori K, Yasuda T, et al. (2001) Effects of vascular endothelial growth factor and E-selectin on angiogenesis in the murine metastatic RCT sarcoma. Tumour Biol 22: 239-246.
    • (2001) Tumour Biol , vol.22 , pp. 239-246
    • Aoki, M.1    Kanamori, M.2    Yudoh, K.3    Ohmori, K.4    Yasuda, T.5
  • 40
    • 0038495928 scopus 로고    scopus 로고
    • Gene expression profile analysis of AIDS-related primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts
    • Klein U, Gloghini A, Gaidano G, Chadburn A, Cesarman E, et al. (2003) Gene expression profile analysis of AIDS-related primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts. Blood 101: 4115-4121.
    • (2003) Blood , vol.101 , pp. 4115-4121
    • Klein, U.1    Gloghini, A.2    Gaidano, G.3    Chadburn, A.4    Cesarman, E.5
  • 41
    • 0042337395 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile
    • Jenner RG, Maillard K, Cattini N, Weiss RA, Boshoff C, et al. (2003) Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile. Proc Natl Acad Sci U S A 100: 10399-10404.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10399-10404
    • Jenner, R.G.1    Maillard, K.2    Cattini, N.3    Weiss, R.A.4    Boshoff, C.5
  • 42
    • 0344152223 scopus 로고    scopus 로고
    • Increased cyclooxygenase-2 (COX-2): a potential role in the pathogenesis of lymphoma
    • Wun T, McKnight H, Tuscano JM, (2004) Increased cyclooxygenase-2 (COX-2): a potential role in the pathogenesis of lymphoma. Leuk Res 28: 179-190.
    • (2004) Leuk Res , vol.28 , pp. 179-190
    • Wun, T.1    McKnight, H.2    Tuscano, J.M.3
  • 43
    • 25144506566 scopus 로고    scopus 로고
    • Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo
    • Kardosh A, Wang W, Uddin J, Petasis NA, Hofman FM, et al. (2005) Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo. Cancer Biol Ther 4: 571-582.
    • (2005) Cancer Biol Ther , vol.4 , pp. 571-582
    • Kardosh, A.1    Wang, W.2    Uddin, J.3    Petasis, N.A.4    Hofman, F.M.5
  • 44
    • 23844444846 scopus 로고    scopus 로고
    • Etodolac inhibits EBER expression and induces Bcl-2-regulated apoptosis in Burkitt's lymphoma cells
    • Kobayashi M, Nakamura S, Shibata K, Sahara N, Shigeno K, et al. (2005) Etodolac inhibits EBER expression and induces Bcl-2-regulated apoptosis in Burkitt's lymphoma cells. Eur J Haematol 75: 212-220.
    • (2005) Eur J Haematol , vol.75 , pp. 212-220
    • Kobayashi, M.1    Nakamura, S.2    Shibata, K.3    Sahara, N.4    Shigeno, K.5
  • 45
    • 0037369240 scopus 로고    scopus 로고
    • The human herpes virus 8-encoded viral FLICE inhibitory protein protects against growth factor withdrawal-induced apoptosis via NF-kappa B activation
    • Sun Q, Matta H, Chaudhary PM, (2003) The human herpes virus 8-encoded viral FLICE inhibitory protein protects against growth factor withdrawal-induced apoptosis via NF-kappa B activation. Blood 101: 1956-1961.
    • (2003) Blood , vol.101 , pp. 1956-1961
    • Sun, Q.1    Matta, H.2    Chaudhary, P.M.3
  • 46
    • 33645744753 scopus 로고    scopus 로고
    • The KSHV oncoprotein vFLIP contains a TRAF-interacting motif and requires TRAF2 and TRAF3 for signalling
    • Guasparri I, Wu H, Cesarman E, (2006) The KSHV oncoprotein vFLIP contains a TRAF-interacting motif and requires TRAF2 and TRAF3 for signalling. EMBO Rep 7: 114-119.
    • (2006) EMBO Rep , vol.7 , pp. 114-119
    • Guasparri, I.1    Wu, H.2    Cesarman, E.3
  • 47
    • 0033599006 scopus 로고    scopus 로고
    • p53 inhibition by the LANA protein of KSHV protects against cell death
    • Friborg J Jr, Kong W, Hottiger MO, Nabel GJ, (1999) p53 inhibition by the LANA protein of KSHV protects against cell death. Nature 402: 889-894.
    • (1999) Nature , vol.402 , pp. 889-894
    • Friborg Jr., J.1    Kong, W.2    Hottiger, M.O.3    Nabel, G.J.4
  • 48
    • 0034791297 scopus 로고    scopus 로고
    • NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis
    • Dormond O, Foletti A, Paroz C, Ruegg C, (2001) NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. Nat Med 7: 1041-1047.
    • (2001) Nat Med , vol.7 , pp. 1041-1047
    • Dormond, O.1    Foletti, A.2    Paroz, C.3    Ruegg, C.4
  • 49
    • 66149115205 scopus 로고    scopus 로고
    • Syndecans shed their reputation as inert molecules
    • Bass MD, Morgan MR, Humphries MJ, (2009) Syndecans shed their reputation as inert molecules. Sci Signal 2: pe18.
    • (2009) Sci Signal , vol.2
    • Bass, M.D.1    Morgan, M.R.2    Humphries, M.J.3
  • 50
    • 70350211844 scopus 로고    scopus 로고
    • The yin and yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth control
    • Campbell FC, Xu H, El-Tanani M, Crowe P, Bingham V, (2010) The yin and yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth control. Biochem Pharmacol 79: 1-9.
    • (2010) Biochem Pharmacol , vol.79 , pp. 1-9
    • Campbell, F.C.1    Xu, H.2    El-Tanani, M.3    Crowe, P.4    Bingham, V.5
  • 52
    • 0034792934 scopus 로고    scopus 로고
    • Chronotherapy and chronotoxicity of the cyclooxygenase-2 inhibitor, celecoxib, in athymic mice bearing human breast cancer xenografts
    • Blumenthal RD, Waskewich C, Goldenberg DM, Lew W, Flefleh C, et al. (2001) Chronotherapy and chronotoxicity of the cyclooxygenase-2 inhibitor, celecoxib, in athymic mice bearing human breast cancer xenografts. Clin Cancer Res 7: 3178-3185.
    • (2001) Clin Cancer Res , vol.7 , pp. 3178-3185
    • Blumenthal, R.D.1    Waskewich, C.2    Goldenberg, D.M.3    Lew, W.4    Flefleh, C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.