NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2

Cancer Investigation

Volumn 27, Issue 1, 2009, Pages 17-23

  Liu, Jun Feng ^a   Zhu, Gui Jun ^a   Jamieson, Glyn G ^b   Wu, Tie Cheng ^a   Zhu, Tie Nian ^a   Shan, Bao En ^a   Drew, Paul A ^c  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF ADELAIDE   (Australia)

^c FLINDERS UNIVERSITY   (Australia)

Author keywords

Apoptosis; COX 2; Esophageal cancer; NF kappaB; NS 398; NSAID

Indexed keywords

CYCLOOXYGENASE 2; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN F1 ALPHA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER PREVENTION; CELL PROLIFERATION; CONCENTRATION RESPONSE; DOWN REGULATION; DRUG INHIBITION; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; FLOW CYTOMETRY; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL NUCLEUS; CELL PROLIFERATION; CYCLOOXYGENASE 2; CYTOPLASM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ESOPHAGEAL NEOPLASMS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; I-KAPPA B PROTEINS; NF-KAPPA B; NITROBENZENES; PROTEIN TRANSPORT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SULFONAMIDES;

EID: 60549114558     PISSN: 07357907     EISSN: 15324192     Source Type: Journal    
DOI: 10.1080/07357900801992913     Document Type: Article

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