Loss of CFTR affects biliary epithelium innate immunity and causes TLR4NF-κB-mediated inflammatory response in mice

Gastroenterology

Volumn 141, Issue 4, 2011, Pages

  Fiorotto, Romina ^a,b   Scirpo, Roberto ^a,c   Trauner, Michael ^d   Fabris, Luca ^b,e   Hoque, Rafaz ^a   Spirli, Carlo ^a,b   Strazzabosco, Mario ^a,b,c  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OSPEDALI RIUNITI   (Italy)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e UNIVERSITY OF PADOVA   (Italy)

Author keywords

Biliary Epithelium; Cystic Fibrosis; Src Kinase; TLR4

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA CHEMOKINE; CD45 ANTIGEN; CHEMOATTRACTANT; CYTOKERATIN 19; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; NEOMYCIN; POLYMYXIN B; PROTEIN TYROSINE KINASE; TOLL LIKE RECEPTOR 4; TRANSCRIPTION FACTOR RELA; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BILE DUCT DISEASE; BILIARY EPITHELIUM; BILIARY TRACT INFLAMMATION; CELL; CELL STRAIN HEK293; CHOLANGIOCYTE; CONTROLLED STUDY; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MOUSE; CYTOKINE RELEASE; ENZYME ACTIVITY; HEPATOBILIARY SYSTEM; HUMAN; HUMAN CELL; INFLAMMATORY INFILTRATE; INNATE IMMUNITY; KNOCKOUT MOUSE; LIVER INJURY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; T LYMPHOCYTE; TRANSMEMBRANE CONDUCTANCE REGULATOR PROTEIN DEFICIENCY; WILD TYPE;

EID: 80053580862     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.06.052     Document Type: Article

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