Insights into the Chloramphenicol Inhibition Effect on Peptidyl Transferase Activity, Using Two New Analogs of the Drug

Open Enzyme Inhibition Journal

Volumn 4, Issue 1, 2011, Pages 1-10

  Kostopoulou, Ourania N ^a   Kourelis, Theodoros G ^a   Mamos, Petros ^a   Magoulas, George E ^b   Kalpaxis, Dimitrios L ^a  

^a UNIVERSITY OF PATRAS   (Greece)

^b UNIVERSITY OF PATRAS   (Greece)

Author keywords

23S rRNA; Chloramphenicol; Chloramphenicol derivatives; Peptide exit tunnel; Peptidyl transferase; Puromycin reaction; Ribosomal A site; Ribosome; Slow binding inhibitors

Indexed keywords

CHLORAMPHENICOL; NUCLEOTIDE; PEPTIDYLTRANSFERASE;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CRYSTALLOGRAPHY; DRUG BINDING; DRUG STRUCTURE; ENZYME ACTIVITY; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN FOOTPRINTING;

ESCHERICHIA COLI; PROKARYOTA; THERMUS THERMOPHILUS;

EID: 80053480606     PISSN: None     EISSN: 18749402     Source Type: Journal    
DOI: 10.2174/1874940201104010001     Document Type: Article

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