Lentivirus-mediated expression of cDNA and shRNA slows degeneration in retinitis pigmentosa

Experimental Biology and Medicine

Volumn 236, Issue 10, 2011, Pages 1211-1217

  Tosi, Joaquin ^a,b,c   Sancho Pelluz, Javier ^a,b   Davis, Richard J ^a,b   Hsu, Chun Wei ^a,b   Wolpert, Kyle V ^a,b   Sengillo, Jesse D ^a,b   Lin, Chyuan Sheng ^a   Tsang, Stephen H ^a,b  

^a College of Physicians and Surgeons ^*  (United States)

^b New York Presbyterian Hospital   (United States)

^c SINAI GRACE HOSPITAL   (United States)

Author keywords

Bipartite; CNGA1; Gene therapy; GUCY2E; Lentiviral vector; Mouse model; PDE6; Pde6b H620Q; Retinitis pigmentosa; shRNA

Indexed keywords

CALCIUM; COMPLEMENTARY DNA; CYCLIC GMP; CYCLIC NUCLEOTIDE GATED CHANNEL; CYCLIC NUCLEOTIDE GATED CHANNEL A1; GUANYLATE CYCLASE; GUANYLATE CYCLASE 2E; LENTIVIRUS VECTOR; PHOSPHODIESTERASE 6BETA; PHOSPHODIESTERASE VI; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION; GENE SILENCING; IMMUNOBLOTTING; MOUSE; NONHUMAN; PHOTORECEPTOR CELL; RETINITIS PIGMENTOSA; VIRAL GENE THERAPY; VIRUS GENE;

ANIMALS; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 6; DNA, COMPLEMENTARY; GENE THERAPY; GENETIC VECTORS; LENTIVIRUS; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; PHOTORECEPTOR CELLS, VERTEBRATE; RETINA; RETINITIS PIGMENTOSA; RNA, SMALL INTERFERING; TRANSDUCTION, GENETIC;

LENTIVIRUS;

EID: 80053439882     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.1258/ebm.2011.011053     Document Type: Article

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