Light, Ca 2+, and photoreceptor death: New evidence for the equivalent- light hypothesis from arrestin knockout mice

Investigative Ophthalmology and Visual Science

Volumn 40, Issue 12, 1999, Pages 2770-2772

  Fain, Gordon L ^a   Lisman, John E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CYCLIC GMP; RETINA S ANTIGEN; CALCIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; CALCIUM CELL LEVEL; DARK ADAPTATION; KNOCKOUT MOUSE; LIGHT DAMAGE; MOUSE; NIGHT BLINDNESS; NONHUMAN; OGUCHI DISEASE; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA DEGENERATION; SHORT SURVEY; VISION; ANIMAL; CELL DEATH; LIGHT; METABOLISM; MOUSE MUTANT; NOTE; PATHOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION INJURY;

ANIMALS; ARRESTIN; CALCIUM; CELL DEATH; LIGHT; MICE; MICE, KNOCKOUT; PHOTORECEPTORS, VERTEBRATE; RADIATION INJURIES, EXPERIMENTAL; RETINAL DEGENERATION;

EID: 0032590225     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (24)

1. Chen J, Simon MI, Matthes MT, Yasumura D, LaVail MM. Increased susceptibility to light damage in an arrestin knockout mouse model of Oguchi disease (stationary night blindness). Invest Ophthalmol Vis Sci. 1999;12:2978-2982.
2. Xu J, Dodd RL, Makino CL, Simon MI, Baylor DA, Chen J. Prolonged photoresponses in transgenic mouse rods lacking arrestin. Nature. 1997;389:505-509.
3. Fuchs S, Nakazawa M, Maw M, Tamai M, Oguchi Y, Gal A. A homozygous 1-base pair deletion in the arrestin gene is a frequent cause of Oguchi disease in Japanese. Nat Genet. 1995; 10:360-362.
4. LaVail MM. Eye pigmentation and constant light damage in the rat retina. In: Williams TP, Baker BN, eds. The Effects of Constant Light on Visual Processes. New York: Plenum Press; 1980:357-387.
5. Fain GL, Lisman JE. Photoreceptor degeneration in vitamin A deprivation and retinitis pigmentosa: the equivalent light hypothesis. Exp Eye Res. 1993;57:335-340.
6. Lisman J, Fain G. Support for the equivalent light hypothesis for RP. Nat Med. 1995;1:1254-1255.
7. Chen C-K, Burns ME, Spencer M, et al. Abnormal photoresponses and light-induced apoptosis in rods lacking rhodopsin kinase. Proc Natl Acad Sci USA. 1999;96:3718-3722.
8. Dryja TP, Finn JT, Peng YW, McGee TL, Berson EL, Yau KW. Mutations in the gene encoding the alpha subunit of the rod cGMP-gated channel in autosomal recessive retinitis pigmentosa. Proc Natl Acad Sci USA. 1995;92:10177-10181.
9. Semple-Rowland SL, Lee NR, Van Hooser JP, Palczewski K, Baehr W. A null mutation in the photoreceptor guanylate cyclase gene causes the retinal degeneration chicken phenotype. Proc Natl Acad Sci USA. 1998;95:1271-6.
10. Kelsell RE, Gregory-Evans K, Payne AM, et al. Mutations in the retinal guanylate cyclase (RETGC-1) gene in dominant cone-rod dystrophy. Hum Mol Genet. 1998;7:1179-1184.
11. Semple-Rowland SL. Guanylyl cyclase is the disease locus in the rd chicken: a model for Leber congenital amaurosis, type 1. In: Hollyfield JG, Anderson RE, LaVail MM, eds. Retinal Degenerative Diseases and Experimental Therapy New York: Plenum; In press.
12. Choi DW. Calcium and excitotoxic neuronal injury. Ann NY Acad Sci. 1994;747:162-171.
13. Green DR, Reed JC. Mitochondria and apoptosis. Science. 1998; 281:1309-1312.
14. Farber DB. From mice to men: the cyclic GMP phosphodiesterase gene in vision and disease. The Proctor Lecture [published correction appears in Invest Ophthalmol Vis Sci 1995;36:976]. Invest Ophthalmol Vis Sci. 1995;36:263-275.
15. Payne AM, Downes SM, Bessant DA, et al. A mutation in guanylate cyclase activator IA (GUCA1A) in an autosomal dominant cone dystrophy pedigree mapping to a new locus on chromosome 6p21.1. Hum Mol Genet. 1998;7:273-277.
16. Sokal I, Li N, Surgucheva I, Warren MJ, et al. GCAP1 (Y99C) mutant is constitutively active in autosomal dominant cone dystrophy. Mol Cell. 1998;2:129-133.
17. Scott BS, Fisher KC. Potassium concentration and number of neurons in cultures of dissociated ganglia. Exp Neurol. 1970;27:16-22.
18. i nflux but not Trk activation. J Neurosci. 1995;15:643-664.
19. Soler RM, Egea J, Mintenig GM, Sanz-Rodriguez C, Iglesias M, Comella JX. Calmodulin is involved in membrane depolarization-mediated survival of motoneurons by phosphatidylinositol-3 kinase and MAPK independent pathways. J Neurosci. 1998;18: 1230-1239.
20. Yano S, Tokumitsu H, Soderling TR. Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway. Nature. 1998;396:584-587.
21. Travis GH. Mechanisms of cell death in the inherited retinal degenerations. Am J Hum Genet. 1998;62:503-508.
22. Yamamoto S, Sippel KC, Berson EL, Dryja TP. Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness. Nat Genet. 1997;15:175-178.
23. Sieving PA, Richards JE, Naarendorp F, Bingham EL, Scott K, Alpern M. Dark-light: model for nightblindness from the human rhodopsin Gly-90→Asp mutation. Proc Natl Acad Sci USA. 1995; 92:880-884.
24. Sampath AP, Matthews HR, Fain GL. Spot-confocal Ca measurements from the outer segments of mouse rod photoreceptors [ARVO Abstract]. Invest Ophthalmol Vis Sci. 1998;39(4):S983.