Triosephosphate isomerase by consensus design: Dramatic differences in physical properties and activity of related variants

Journal of Molecular Biology

Volumn 413, Issue 1, 2011, Pages 195-208

  Sullivan, Brandon J ^a   Durani, Venuka ^a   Magliery, Thomas J ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

consensus design; molten globule; oligomeric state; protein engineering; sequence correlation

Indexed keywords

DIMER; ENZYME VARIANT; MONOMER; OLIGOMER; TRIOSEPHOSPHATE ISOMERASE;

ARTICLE; CONSENSUS SEQUENCE; DIFFUSION; DIMERIZATION; ENZYME ANALYSIS; ENZYME ENGINEERING; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE DATABASE;

EID: 80053332184     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2011.08.001     Document Type: Article

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