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Volumn 38, Issue 4, 2011, Pages 639-648

ERK5: A novel IKKα-kinase in rat hippocampal neurons

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TUBULIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; I KAPPA B BETA; I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 7; SMALL INTERFERING RNA; TAU PROTEIN; WORTMANNIN; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); ANDROSTANE DERIVATIVE; ANTIDIABETIC AGENT; ENZYME INHIBITOR; PEPTIDE FRAGMENT;

EID: 80053299781     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/s0317167100012191     Document Type: Article
Times cited : (6)

References (41)
  • 1
    • 33750731675 scopus 로고    scopus 로고
    • 100 years and counting: Prospects for defeating Alzheimer's disease
    • Roberson ED, Mucke L. 100 years and counting: prospects for defeating Alzheimer's disease. Science. 2006;314:781-4.
    • (2006) Science , vol.314 , pp. 781-784
    • Roberson, E.D.1    Mucke, L.2
  • 2
    • 52249115856 scopus 로고    scopus 로고
    • Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
    • Busche MA, Eichhoff G, Adelsberger H, et al. Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease. Science. 2008;321:1686-9.
    • (2008) Science , vol.321 , pp. 1686-1689
    • Busche, M.A.1    Eichhoff, G.2    Adelsberger, H.3
  • 3
    • 34547653872 scopus 로고    scopus 로고
    • Tau phosphorylation by GSK-3beta promotes tangle-like filament morphology
    • Rankin CA, Sun Q, Gamblin TC. Tau phosphorylation by GSK-3beta promotes tangle-like filament morphology. Mol Neurodegener. 2007;2:12-3.
    • (2007) Mol Neurodegener , vol.2 , pp. 12-13
    • Rankin, C.A.1    Sun, Q.2    Gamblin, T.C.3
  • 4
    • 0346216156 scopus 로고    scopus 로고
    • Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI
    • den Heijer T, Vermeer SE, van Dijk EJ, et al. Type 2 diabetes and atrophy of medial temporal lobe structures on brain MRI. Diabetologia. 2003;46:1604-10.
    • (2003) Diabetologia , vol.46 , pp. 1604-1610
    • Den Heijer, T.1    Vermeer, S.E.2    Van Dijk, E.J.3
  • 6
    • 0031453240 scopus 로고    scopus 로고
    • Insulin resistance and atherosclerosis
    • Chen Y-DI and Reaven GM. Insulin resistance and atherosclerosis. Diabetes Rev. 1997;4:331-42.
    • (1997) Diabetes Rev , vol.4 , pp. 331-342
    • Y-Di, C.1    Reaven, G.M.2
  • 7
    • 0033968126 scopus 로고    scopus 로고
    • Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle
    • Cusi K, Maezono K, Osman A, et al. Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle. J Clin Invest. 2000;105:311-20.
    • (2000) J Clin Invest , vol.105 , pp. 311-320
    • Cusi, K.1    Maezono, K.2    Osman, A.3
  • 8
    • 0034792844 scopus 로고    scopus 로고
    • Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice
    • Ng SS, Tsao MS, Nicklee T, Hedley DW. Wortmannin inhibits pkb/akt phosphorylation and promotes gemcitabine antitumor activity in orthotopic human pancreatic cancer xenografts in immunodeficient mice. Clin Cancer Res. 2001;7:3269-75.
    • (2001) Clin Cancer Res , vol.7 , pp. 3269-3275
    • Ng, S.S.1    Tsao, M.S.2    Nicklee, T.3    Hedley, D.W.4
  • 9
  • 10
    • 14444278515 scopus 로고    scopus 로고
    • Insulin potentiates platelet-derived growth factor action in vascular smooth muscle cells
    • Goalstone ML, Natarajan R, Standley PR, et al. Insulin potentiates platelet-derived growth factor action in vascular smooth muscle cells. Endocrinology. 1998;139:4067-72.
    • (1998) Endocrinology , vol.139 , pp. 4067-4072
    • Goalstone, M.L.1    Natarajan, R.2    Standley, P.R.3
  • 12
    • 0034644757 scopus 로고    scopus 로고
    • Potentiation of Rho-Amediated lysophophatidic acid activity by hyperinsulinemia
    • Chappell J, Golovchenko I, Wall K, et al. Potentiation of Rho-Amediated lysophophatidic acid activity by hyperinsulinemia. J Biol Chem. 2000;275:31792-7.
    • (2000) J Biol Chem , vol.275 , pp. 31792-31797
    • Chappell, J.1    Golovchenko, I.2    Wall, K.3
  • 13
    • 27844472159 scopus 로고    scopus 로고
    • Increased risk of Alzheimer's disease in Type II diabetes: Insulin resistance of the brain or insulininduced amyloid pathology?
    • Biessels GJ Kappelle LJ. Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulininduced amyloid pathology? Biochem Soc Trans. 2005;33: 1041-4.
    • (2005) Biochem Soc Trans , vol.33 , pp. 1041-1044
    • Biessels, G.J.1    Kappelle, L.J.2
  • 14
  • 15
    • 15244350991 scopus 로고    scopus 로고
    • Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: Relevance to Alzheimer's disease
    • de la Monte SM, Wands JR. Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease. J Alzheimers Dis. 2005;7:45-61.
    • (2005) J Alzheimers Dis , vol.7 , pp. 45-61
    • De La Monte, S.M.1    Wands, J.R.2
  • 16
    • 28444495045 scopus 로고    scopus 로고
    • Neuronal insulin signal transduction mechanisms in diabetes phenotypes
    • Reagan LP. Neuronal insulin signal transduction mechanisms in diabetes phenotypes. Neurobiol Aging. 2005;26 Suppl 1:56-9.
    • (2005) Neurobiol Aging , vol.26 , Issue.SUPPL. 1 , pp. 56-59
    • Reagan, L.P.1
  • 17
    • 0034456622 scopus 로고    scopus 로고
    • Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide
    • Aljada A, Saadeh R, Assian E, Ghanim H, Dandona P. Insulin inhibits the expression of intercellular adhesion molecule-1 by human aortic endothelial cells through stimulation of nitric oxide. J Clin Endo Metab. 2000;85:2572-5.
    • (2000) J Clin Endo Metab , vol.85 , pp. 2572-2575
    • Aljada, A.1    Saadeh, R.2    Assian, E.3    Ghanim, H.4    Dandona, P.5
  • 18
    • 0034721925 scopus 로고    scopus 로고
    • Hyperinsulinemia enhances transcriptional activity of NF?B induced by angiotensin II, hyperglycemia and advanced glycosylation end products in vascular smooth muscle cells
    • Golovchenko I, Goalstone ML, Watson P, Brownlee M, Draznin B. Hyperinsulinemia enhances transcriptional activity of NF?B induced by angiotensin II, hyperglycemia and advanced glycosylation end products in vascular smooth muscle cells. Circ Res. 2000;87:746-52.
    • (2000) Circ Res , vol.87 , pp. 746-752
    • Golovchenko, I.1    Goalstone, M.L.2    Watson, P.3    Brownlee, M.4    Draznin, B.5
  • 20
    • 0035896513 scopus 로고    scopus 로고
    • ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation
    • Pearson G, English JM, White MA, Cobb MH. ERK5 and ERK2 cooperate to regulate NF-kappaB and cell transformation. J Biol Chem. 2001;276:7927-31.
    • (2001) J Biol Chem , vol.276 , pp. 7927-7931
    • Pearson, G.1    English, J.M.2    White, M.A.3    Cobb, M.H.4
  • 21
    • 34247540411 scopus 로고    scopus 로고
    • Regulation of the G2-M cell cycle progression by the ERK5-NFkappaB signaling pathway
    • Cude K, Wang Y, Choi HJ, et al. Regulation of the G2-M cell cycle progression by the ERK5-NFkappaB signaling pathway. J Cell Biol. 2007;177:253-64.
    • (2007) J Cell Biol , vol.177 , pp. 253-264
    • Cude, K.1    Wang, Y.2    Choi, H.J.3
  • 22
    • 33846782998 scopus 로고    scopus 로고
    • Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells
    • Sharma G, Goalstone ML. Regulation of ERK5 by insulin and angiotensin-II in vascular smooth muscle cells. Biochem Biophys Res Commun. 2007;354:1078-83.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 1078-1083
    • Sharma, G.1    Goalstone, M.L.2
  • 23
    • 33847627937 scopus 로고    scopus 로고
    • Inhibition of Abeta production by NF-kappaB inhibitors
    • Paris D, Patel N, Quadros A, et al. Inhibition of Abeta production by NF-kappaB inhibitors. Neurosci Lett. 2007;415:11-6.
    • (2007) Neurosci Lett , vol.415 , pp. 11-16
    • Paris, D.1    Patel, N.2    Quadros, A.3
  • 24
    • 0028031569 scopus 로고
    • Reduced tyrosine kinase activity of the insulin receptor in obesitydiabetes. Central role of tumor necrosis factor-alpha
    • Hotamisligil GS, Budavari A, Murray D, Spiegelman BM. Reduced tyrosine kinase activity of the insulin receptor in obesitydiabetes. Central role of tumor necrosis factor-alpha. J Clin Invest. 1994;94:1543-9.
    • (1994) J Clin Invest , vol.94 , pp. 1543-1549
    • Hotamisligil, G.S.1    Budavari, A.2    Murray, D.3    Spiegelman, B.M.4
  • 25
    • 9244231209 scopus 로고    scopus 로고
    • Influence of diabetes on the exacerbation of an inflammatory response in cardiovascular tissue
    • Lu H, Raptis M, Black E, Stan M, Amar S, Graves DT. Influence of diabetes on the exacerbation of an inflammatory response in cardiovascular tissue. Endocrinology. 2004;145:4934-9.
    • (2004) Endocrinology , vol.145 , pp. 4934-4939
    • Lu, H.1    Raptis, M.2    Black, E.3    Stan, M.4    Amar, S.5    Graves, D.T.6
  • 26
    • 0030271387 scopus 로고    scopus 로고
    • NF-kappa B: Ten years after
    • Baeuerle PA, Baltimore D. NF-kappa B: ten years after. Cell. 1996; 87:13-20.
    • (1996) Cell , vol.87 , pp. 13-20
    • Baeuerle, P.A.1    Baltimore, D.2
  • 27
    • 0029874138 scopus 로고    scopus 로고
    • The NF-kappa B and i kappa B proteins: New discoveries and insights
    • Baldwin AS. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immun 1996;14:49-83.
    • (1996) Annu Rev Immun , vol.14 , pp. 49-83
    • Baldwin, A.S.1
  • 28
    • 0031897632 scopus 로고    scopus 로고
    • NF-kappa B and Rel proteins: Evolutionarily conserved mediators of immune responses
    • Ghosh S, May MJ, Kopp EB. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu Rev Immunol. 1998;16:225-60.
    • (1998) Annu Rev Immunol , vol.16 , pp. 225-260
    • Ghosh, S.1    May, M.J.2    Kopp, E.B.3
  • 29
    • 0030747128 scopus 로고    scopus 로고
    • NF?B as a frequent target for immunosuppressive and anti-inflamatory molecules
    • Baeuerle PA, Baichwal VP. NF?B as a frequent target for immunosuppressive and anti-inflamatory molecules. Adv Immunol. 1997;65:111-37.
    • (1997) Adv Immunol , vol.65 , pp. 111-137
    • Baeuerle, P.A.1    Baichwal, V.P.2
  • 30
    • 0030851775 scopus 로고    scopus 로고
    • The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro
    • Ghoda L, Lin X, Greene WC. The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IkappaBalpha and stimulates its degradation in vitro. J Biol Chem. 1997;272:21281-8.
    • (1997) J Biol Chem , vol.272 , pp. 21281-21288
    • Ghoda, L.1    Lin, X.2    Greene, W.C.3
  • 31
    • 0030004897 scopus 로고    scopus 로고
    • Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity
    • Chen ZJ, Parent L, Maniatis T. Site-specific phosphorylation of IkappaBalpha by a novel ubiquitination-dependent protein kinase activity. Cell. 1996;84:853-62.
    • (1996) Cell , vol.84 , pp. 853-862
    • Chen, Z.J.1    Parent, L.2    Maniatis, T.3
  • 32
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKKrelated kinases
    • Hacker H, Karin M. Regulation and function of IKK and IKKrelated kinases. Sci STKE. 2006;2006:re13.
    • (2006) Sci STKE , vol.2006
    • Hacker, H.1    Karin, M.2
  • 33
    • 30544451546 scopus 로고    scopus 로고
    • Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6
    • Hacker H, Redecke V, Blagoev B, et al. Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6. Nature. 2006;439:204-7.
    • (2006) Nature , vol.439 , pp. 204-207
    • Hacker, H.1    Redecke, V.2    Blagoev, B.3
  • 34
    • 0034769309 scopus 로고    scopus 로고
    • Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells
    • Dinev D, Jordan BW, Neufeld B, et al. Extracellular signal regulated kinase 5 (ERK5) is required for the differentiation of muscle cells. EMBO Rep. 2001;2:829-34.
    • (2001) EMBO Rep , vol.2 , pp. 829-834
    • Dinev, D.1    Jordan, B.W.2    Neufeld, B.3
  • 36
    • 2942522558 scopus 로고    scopus 로고
    • Role of extracellular signal regulated kinase 5 in neuronal survival
    • Cavanaugh JE. Role of extracellular signal regulated kinase 5 in neuronal survival. Eur J Biochem. 2004;271:2056-9.
    • (2004) Eur J Biochem , vol.271 , pp. 2056-2059
    • Cavanaugh, J.E.1
  • 37
    • 0038491472 scopus 로고    scopus 로고
    • ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons
    • Liu L, Cavanaugh JE, Wang Y, Sakagami H, Mao Z, Xia Z. ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons. Proc Natl Acad Sci USA. 2003;100:8532-7.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 8532-8537
    • Liu, L.1    Cavanaugh, J.E.2    Wang, Y.3    Sakagami, H.4    Mao, Z.5    Xia, Z.6
  • 38
    • 30044435224 scopus 로고    scopus 로고
    • Dominant negative FTase (DNFTalpha) inhibits ERK5 MEF2C and CREB activation in adipogenesis
    • Sharma G, Goalstone ML. Dominant negative FTase (DNFTalpha) inhibits ERK5, MEF2C and CREB activation in adipogenesis. Mol Cell Endocrinol. 2005;245:93-104.
    • (2005) Mol Cell Endocrinol , vol.245 , pp. 93-104
    • Sharma, G.1    Goalstone, M.L.2
  • 39
    • 15244351255 scopus 로고    scopus 로고
    • Impaired insulin and insulinlike growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes?
    • Steen E, Terry BM, Rivera EJ, et al. Impaired insulin and insulinlike growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimers Dis. 2005;7:63-80.
    • (2005) J Alzheimers Dis , vol.7 , pp. 63-80
    • Steen, E.1    Terry, B.M.2    Rivera, E.J.3
  • 40
    • 0038725009 scopus 로고    scopus 로고
    • Neuroscience. Insulin insults may spur Alzheimer's disease
    • Taubes G. Neuroscience. Insulin insults may spur Alzheimer's disease. Science. 2003;301:40-1.
    • (2003) Science , vol.301 , pp. 40-41
    • Taubes, G.1
  • 41
    • 0036759508 scopus 로고    scopus 로고
    • Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: A population-based study of the oldest old
    • Hassing LB, Johansson B, Nilsson SE, et al. Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: a population-based study of the oldest old. Int Psychogeriatr. 2002;14:239-48.
    • (2002) Int Psychogeriatr , vol.14 , pp. 239-248
    • Hassing, L.B.1    Johansson, B.2    Nilsson, S.E.3


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