메뉴 건너뛰기




Volumn 712, Issue , 2011, Pages 155-176

Proteases in blood-feeding nematodes and their potential as vaccine candidates

Author keywords

[No Author keywords available]

Indexed keywords

ANTIPARASITIC AGENT; ASPARTIC PROTEINASE; CAENORHABDITIS ELEGANS PROTEIN; CATHEPSIN B; CONTORTIN; CYSTEINE PROTEINASE; GLYCAN; H GAL GP PROTEIN; HEAT SHOCK PROTEIN 22; HEMOGLOBIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LEGUMAIN; METALLOPROTEINASE; PROTEINASE; UNCLASSIFIED DRUG; PEPTIDE HYDROLASE; VACCINE;

EID: 80053296202     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-8414-2_10     Document Type: Article
Times cited : (36)

References (97)
  • 1
    • 0030746305 scopus 로고    scopus 로고
    • Nutritional adaptations to parasitism within the platyhelminthes
    • Halton D. Nutritional adaptations to parasitism within the platyhelminthes. Int J Parasitol 1997; 27:693-704
    • (1997) Int J Parasitol , vol.27 , pp. 693-704
    • Halton, D.1
  • 2
    • 0013671026 scopus 로고
    • Studies on the mechanism of immunity in the rat to the nematode, Nippostrongylus muris
    • Thorson RE. Studies on the mechanism of immunity in the rat to the nematode, Nippostrongylus muris. Am J Hyg 1953; 58:1-15
    • (1953) Am J Hyg , vol.58 , pp. 1-15
    • Thorson, R.E.1
  • 3
    • 50449130331 scopus 로고
    • Effect of immune serum from rats on infective larvae of Nippostrongylus muris
    • Thorson RE. Effect of immune serum from rats on infective larvae of Nippostrongylus muris. Exp Parasitol 1954; 3:9-15
    • (1954) Exp Parasitol , vol.3 , pp. 9-15
    • Thorson, R.E.1
  • 4
    • 84961005926 scopus 로고
    • Proteolytic activity in extracts of the esophagus of adults of Ancylostoma caninum and the effect of immune serum on this activity
    • Thorson RE. Proteolytic activity in extracts of the esophagus of adults of Ancylostoma caninum and the effect of immune serum on this activity. J Parasitol 1956; 42:21-25
    • (1956) J Parasitol , vol.42 , pp. 21-25
    • Thorson, R.E.1
  • 5
    • 0000150285 scopus 로고
    • The stimulation of acquired immunity in dogs by injections of extracts of the esophagus of adult hookworms
    • Thorson RE. The stimulation of acquired immunity in dogs by injections of extracts of the esophagus of adult hookworms. J Parasitol 1956b; 42:501-504
    • (1956) J Parasitol , vol.42 , pp. 501-504
    • Thorson, R.E.1
  • 6
    • 4143054944 scopus 로고    scopus 로고
    • A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms
    • Williamson A, Lecchi P, Turk BE et al. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. J Biol Chem 2003; 279:35950-35957
    • (2003) J Biol Chem , vol.279 , pp. 35950-35957
    • Williamson, A.1    Lecchi, P.2    Turk, B.E.3
  • 7
    • 0002686989 scopus 로고
    • Studies of a proteolytic enzyme from Schistosoma mansoni
    • Timms AR, Bueding E. Studies of a proteolytic enzyme from Schistosoma mansoni. Br J Pharmacol Chemother 1959; 14:68-73
    • (1959) Br J Pharmacol Chemother , vol.14 , pp. 68-73
    • Timms, A.R.1    Bueding, E.2
  • 8
    • 0025344095 scopus 로고
    • Studies on the presence and release ofproteolytic enzymes (proteinases) in gastro-intestinal nematodes of ruminants
    • Knox DP, Jones, DG. Studies on the presence and release ofproteolytic enzymes (proteinases) in gastro-intestinal nematodes of ruminants. Int J Parasitol 1990; 20:243-249
    • (1990) Int J Parasitol , vol.20 , pp. 243-249
    • Knox, D.P.1    Jones, D.G.2
  • 9
    • 0025368407 scopus 로고
    • Molecular cloning and primary sequence of a cysteine protease expressed by Haemonchus contortus adult worms
    • Cox GN, Pratt D, Hageman R et al. Molecular cloning and primary sequence of a cysteine protease expressed by Haemonchus contortus adult worms. Mol Biochem Parasitol 1990; 41:25-34
    • (1990) Mol Biochem Parasitol , vol.41 , pp. 25-34
    • Cox, G.N.1    Pratt, D.2    Hageman, R.3
  • 10
    • 0025129499 scopus 로고
    • A developmentally regulated cysteine protease gene family in Haemonchus contortus
    • Pratt D, Cox GN, Milhausen MJ et al. A developmentally regulated cysteine protease gene family in Haemonchus contortus. Mol Biochem Parasitol 1990; 43:181-191
    • (1990) Mol Biochem Parasitol , vol.43 , pp. 181-191
    • Pratt, D.1    Cox, G.N.2    Milhausen, M.J.3
  • 11
    • 0026539432 scopus 로고
    • Cloning and sequence comparisons of four distinct cysteine proteases expressed by Haemonchus contortus adult worms
    • Pratt D, Armes LG, Hageman R et al. Cloning and sequence comparisons of four distinct cysteine proteases expressed by Haemonchus contortus adult worms. Mol Biochem Parasitol 1992; 51:209-218
    • (1992) Mol Biochem Parasitol , vol.51 , pp. 209-218
    • Pratt, D.1    Armes, L.G.2    Hageman, R.3
  • 12
    • 0026888530 scopus 로고
    • Fibrinogen-degrading proteins from Haemonchus contortus used to vaccinate sheep
    • Boisvenue RJ, Stiff MI, Tonkinson LV et al. Fibrinogen-degrading proteins from Haemonchus contortus used to vaccinate sheep. Am J Vet Res 1992; 53:1263-1265
    • (1992) Am J Vet Res , vol.53 , pp. 1263-1265
    • Boisvenue, R.J.1    Stiff, M.I.2    Tonkinson, L.V.3
  • 13
    • 0027264026 scopus 로고
    • Characterization of proteinases in extracts of adult Haemonchus contortus, the ovine abomasal nematode
    • Knox DP, Redmond DL, Jones DG. Characterization of proteinases in extracts of adult Haemonchus contortus, the ovine abomasal nematode. Parasitology 1993; 106:395-404
    • (1993) Parasitology , vol.106 , pp. 395-404
    • Knox, D.P.1    Redmond, D.L.2    Jones, D.G.3
  • 14
    • 0030997936 scopus 로고    scopus 로고
    • The in vitro uptake and incorporation ofhemoglobin by adult Haemonchus-contortus
    • Fetterer RH, Rhoads ML. The in vitro uptake and incorporation ofhemoglobin by adult Haemonchus-contortus. Vet Parasitol 1997; 69:77-87
    • (1997) Vet Parasitol , vol.69 , pp. 77-87
    • Fetterer, R.H.1    Rhoads, M.L.2
  • 15
    • 0001938437 scopus 로고
    • Vaccination with concealed antigens for tick control
    • Willadsen P, Kemp DH. Vaccination with 'concealed' antigens for tick control. Parasitol Today 1988 J; 4:196-198
    • (1988) Parasitol Today , vol.4 , pp. 196-198
    • Willadsen, P.1    Kemp, D.H.2
  • 16
    • 84976003225 scopus 로고
    • Vaccination of young lambs by means of a protein fraction extracted from adult Haemonchus contortus
    • Munn EA, Greenwood CA, Coadwell WJ. Vaccination of young lambs by means of a protein fraction extracted from adult Haemonchus contortus. Parasitology 1987; 94:385-97
    • (1987) Parasitology , vol.94 , pp. 385-97
    • Munn, E.A.1    Greenwood, C.A.2    Coadwell, W.J.3
  • 17
    • 0017329807 scopus 로고
    • A helical, polymeric extracellular protein associated with the luminal surface of Haemonchus contortus intestinal cells
    • Munn EA. A helical, polymeric extracellular protein associated with the luminal surface of Haemonchus contortus intestinal cells. Tissue Cell 1977; 9:23-34
    • (1977) Tissue Cell , vol.9 , pp. 23-34
    • Munn, E.A.1
  • 18
    • 0033102205 scopus 로고    scopus 로고
    • The development ofvaccines against gastrointestinal nematode parasites, particularly Haemonchus contortus
    • Newton SE, Munn EA. The development ofvaccines against gastrointestinal nematode parasites, particularly Haemonchus contortus. Parasitol Today 1999; 15:116-122
    • (1999) Parasitol Today , vol.15 , pp. 116-122
    • Newton, S.E.1    Munn, E.A.2
  • 19
    • 0030040696 scopus 로고    scopus 로고
    • Immunisation of sheep with an integral membrane glycoprotein complex of Haemonchus contortus and with its major polypeptide components
    • Smith SK, Smith WD. Immunisation of sheep with an integral membrane glycoprotein complex of Haemonchus contortus and with its major polypeptide components. Res Vet Sci 1996; 60:1-6
    • (1996) Res Vet Sci , vol.60 , pp. 1-6
    • Smith, S.K.1    Smith, W.D.2
  • 20
    • 42249086434 scopus 로고    scopus 로고
    • Vaccination against Haemonchus contortus: Performance of native parasite gut membrane glycoproteins in Merino lambs grazing contaminated pasture
    • LeJambre LF, Windon RG, Smith WD. Vaccination against Haemonchus contortus: performance of native parasite gut membrane glycoproteins in Merino lambs grazing contaminated pasture. Vet Parasitol 2008; 153:302-312
    • (2008) Vet Parasitol , vol.153 , pp. 302-312
    • Lejambre, L.F.1    Windon, R.G.2    Smith, W.D.3
  • 21
    • 0030787590 scopus 로고    scopus 로고
    • Vaccination against Haemonchus contortus with denatured forms of the protective antigen H11
    • Munn EA, Smith TS, Smith H et al. Vaccination against Haemonchus contortus with denatured forms of the protective antigen H11. Parasite Immunol 1997; 19:243-248
    • (1997) Parasite Immunol , vol.19 , pp. 243-248
    • Munn, E.A.1    Smith, T.S.2    Smith, H.3
  • 22
    • 0030915280 scopus 로고    scopus 로고
    • Cloning and characterization of a microsomal aminopeptidase from the intestine of the nematode Haemonchus contortus
    • Smith TS, Graham M, Munn EA et al. Cloning and characterization of a microsomal aminopeptidase from the intestine of the nematode Haemonchus contortus. Biochim Biophys Acta 1997; 1338:295-306
    • (1997) Biochim Biophys Acta , vol.1338 , pp. 295-306
    • Smith, T.S.1    Graham, M.2    Munn, E.A.3
  • 23
    • 0029852531 scopus 로고    scopus 로고
    • Haemonchus contortus glycoproteins contain N-linked oligosaccharides with novel highly fucosylated core structures
    • Haslam SM, Coles GC, Munn EA et al. Haemonchus contortus glycoproteins contain N-linked oligosaccharides with novel highly fucosylated core structures. J Biol Chem 1996; 271:30561-30570
    • (1996) J Biol Chem , vol.271 , pp. 30561-30570
    • Haslam, S.M.1    Coles, G.C.2    Munn, E.A.3
  • 24
    • 0028352469 scopus 로고
    • Protection studies with integral membrane fractions of Haemonchus contortus
    • Smith WD, Smith SK, Murray JM. Protection studies with integral membrane fractions of Haemonchus contortus. Parasite Immunol 1994; 16:231-41
    • (1994) Parasite Immunol , vol.16 , pp. 231-41
    • Smith, W.D.1    Smith, S.K.2    Murray, J.M.3
  • 25
    • 0030875082 scopus 로고    scopus 로고
    • Molecular cloning and characterisation of a putative aspartyl proteinase associated with a gut membrane protein complex from adult Haemonchus contortus
    • Longbottom D, Redmond DL, Russell M et al. Molecular cloning and characterisation of a putative aspartyl proteinase associated with a gut membrane protein complex from adult Haemonchus contortus. Mol Biochem Parasitol 1997; 88:63-72
    • (1997) Mol Biochem Parasitol , vol.88 , pp. 63-72
    • Longbottom, D.1    Redmond, D.L.2    Russell, M.3
  • 26
    • 0030949381 scopus 로고    scopus 로고
    • Molecular cloning and characterisation of a developmentally regulated putative metallopeptidase present in a host protective extract of Haemonchus contortus
    • Redmond DL, Knox DP, Newlands G et al. Molecular cloning and characterisation of a developmentally regulated putative metallopeptidase present in a host protective extract of Haemonchus contortus. Mol Biochem Parasitol 1997; 85:77-87
    • (1997) Mol Biochem Parasitol , vol.85 , pp. 77-87
    • Redmond, D.L.1    Knox, D.P.2    Newlands, G.3
  • 27
    • 0032898118 scopus 로고    scopus 로고
    • Further immunization and biochemical studies with a protective antigen complex from the microvillar membrane of the intestine of Haemonchus contortus
    • Smith SK, Pettit D, Newlands GF et al. Further immunization and biochemical studies with a protective antigen complex from the microvillar membrane of the intestine of Haemonchus contortus. Parasite Immunol 1999; 21:187-199
    • (1999) Parasite Immunol , vol.21 , pp. 187-199
    • Smith, S.K.1    Pettit, D.2    Newlands, G.F.3
  • 28
    • 0032723342 scopus 로고    scopus 로고
    • Cloning and characterization of a beta-galactoside-binding protein (galectin) from the gut of the gastrointestinal nematode parasite Haemonchus contortus
    • Newlands GF, Skuce PJ, Knox DP et al. Cloning and characterization of a beta-galactoside-binding protein (galectin) from the gut of the gastrointestinal nematode parasite Haemonchus contortus. Parasitology 1999; 119:483-490
    • (1999) Parasitology , vol.119 , pp. 483-490
    • Newlands, G.F.1    Skuce, P.J.2    Knox, D.P.3
  • 29
    • 0034799036 scopus 로고    scopus 로고
    • Cloning and characterisation of thrombospondin, a novel multidomain glycoprotein found in association with a host protective gut extract from Haemonchus contortus
    • Skuce PJ, Newlands GF, Stewart EM et al. Cloning and characterisation of thrombospondin, a novel multidomain glycoprotein found in association with a host protective gut extract from Haemonchus contortus. Mol Biochem Parasitol 2001; 117:241-244
    • (2001) Mol Biochem Parasitol , vol.117 , pp. 241-244
    • Skuce, P.J.1    Newlands, G.F.2    Stewart, E.M.3
  • 30
    • 33747064365 scopus 로고    scopus 로고
    • Molecular characterization of a family of metalloendopeptidases from the intestinal brush border of Haemonchus contortus
    • Newlands GF, Skuce PJ, Nisbet AJ et al. Molecular characterization of a family of metalloendopeptidases from the intestinal brush border of Haemonchus contortus. Parasitology 2006; 133:357-368
    • (2006) Parasitology , vol.133 , pp. 357-368
    • Newlands, G.F.1    Skuce, P.J.2    Nisbet, A.J.3
  • 31
    • 0033976163 scopus 로고    scopus 로고
    • Relative protective properties ofthree membrane glycoprotein fractions from Haemonchus contortus
    • Smith WD, Smith SK, Pettit D et al. Relative protective properties ofthree membrane glycoprotein fractions from Haemonchus contortus. Parasite Immunol 2000; 22:63-71
    • (2000) Parasite Immunol , vol.22 , pp. 63-71
    • Smith, W.D.1    Smith, S.K.2    Pettit, D.3
  • 32
    • 0347510968 scopus 로고    scopus 로고
    • Metalloendopeptidases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep
    • Smith WD, Newlands GF, Smith SK et al. Metalloendopeptidases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep. Parasite Immunol 2003; 25:313-323
    • (2003) Parasite Immunol , vol.25 , pp. 313-323
    • Smith, W.D.1    Newlands, G.F.2    Smith, S.K.3
  • 33
    • 1842586936 scopus 로고    scopus 로고
    • Aspartyl proteases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep
    • Smith WD, Skuce PJ, Newlands GF et al. Aspartyl proteases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep. Parasite Immunol 2003; 25:521-530
    • (2003) Parasite Immunol , vol.25 , pp. 521-530
    • Smith, W.D.1    Skuce, P.J.2    Newlands, G.F.3
  • 34
    • 7944237048 scopus 로고    scopus 로고
    • Evaluation of Caenorhabditis elegans glycoproteins as protective immunogens against Haemonchus contortus challenge in sheep
    • Redmond DL, Geldhof P, Knox DP. Evaluation of Caenorhabditis elegans glycoproteins as protective immunogens against Haemonchus contortus challenge in sheep. Int J Parasitol 2004; 34:1347-1353
    • (2004) Int J Parasitol , vol.34 , pp. 1347-1353
    • Redmond, D.L.1    Geldhof, P.2    Knox, D.P.3
  • 35
    • 4644337865 scopus 로고    scopus 로고
    • MRNA sequences for Haemonchus contortus intestinal cathepsin B-like cysteine proteases display an extreme in abundance and diversity compared with other adult mammalian parasitic nematodes
    • Jasmer DP, Mitreva MD, McCarter JP. mRNA sequences for Haemonchus contortus intestinal cathepsin B-like cysteine proteases display an extreme in abundance and diversity compared with other adult mammalian parasitic nematodes. Mol Biochem Parasitol 2004; 137:297-305
    • (2004) Mol Biochem Parasitol , vol.137 , pp. 297-305
    • Jasmer, D.P.1    Mitreva, M.D.2    McCarter, J.P.3
  • 36
    • 33646789135 scopus 로고    scopus 로고
    • A survey of the intestinal transcriptomes of the hookworms, Necator americanus and Ancylostoma caninum, using tissues isolated by laser microdissection microscopy
    • Ranjit N, Jones MK, Stenzel DJ et al. A survey of the intestinal transcriptomes of the hookworms, Necator americanus and Ancylostoma caninum, using tissues isolated by laser microdissection microscopy. Int J Parasitol 2006; 36:701-710
    • (2006) Int J Parasitol , vol.36 , pp. 701-710
    • Ranjit, N.1    Jones, M.K.2    Stenzel, D.J.3
  • 37
    • 50049136204 scopus 로고    scopus 로고
    • A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus
    • Ranjit N, Zhan B, Stenzel DJ et al. A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Mol Biocheml Parasitol 2008; 160:90-99
    • (2008) Mol Biocheml Parasitol , vol.160 , pp. 90-99
    • Ranjit, N.1    Zhan, B.2    Stenzel, D.J.3
  • 38
    • 0032920180 scopus 로고    scopus 로고
    • Immunization with an affinity purified protein extract from the adult parasite protects lambs against infection with Haemonchus contortus
    • Knox DP, Smith SK, Smith WD. Immunization with an affinity purified protein extract from the adult parasite protects lambs against infection with Haemonchus contortus. Parasite Immunol 1999; 21:201-210
    • (1999) Parasite Immunol , vol.21 , pp. 201-210
    • Knox, D.P.1    Smith, S.K.2    Smith, W.D.3
  • 39
    • 4944238853 scopus 로고    scopus 로고
    • Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortus
    • Redmond DL, Knox DP. Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortus. Vaccine 2004; 22:4252-4261
    • (2004) Vaccine , vol.22 , pp. 4252-4261
    • Redmond, D.L.1    Knox, D.P.2
  • 40
    • 0032835839 scopus 로고    scopus 로고
    • Molecular cloning and characterization of gut-derived cysteine proteinases associated with a host protective extract from Haemonchus contortus
    • Skuce PJ, Redmond DL, Liddell S et al. Molecular cloning and characterization of gut-derived cysteine proteinases associated with a host protective extract from Haemonchus contortus.Parasitology 1999; 119:405-412
    • (1999) Parasitology , vol.119 , pp. 405-412
    • Skuce, P.J.1    Redmond, D.L.2    Liddell, S.3
  • 41
    • 4944238853 scopus 로고    scopus 로고
    • Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortus
    • Redmond DL, Knox DP. Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortus. Vaccine 2004; 22:4252-4261
    • (2004) Vaccine , vol.22 , pp. 4252-4261
    • Redmond, D.L.1    Knox, D.P.2
  • 42
    • 33645839305 scopus 로고    scopus 로고
    • Further protection studies using recombinant forms of Haemonchus contortus cysteine proteinases
    • Redmond DL, Knox DP. Further protection studies using recombinant forms of Haemonchus contortus cysteine proteinases. Parasite Immunol 2006; 28:213-219
    • (2006) Parasite Immunol , vol.28 , pp. 213-219
    • Redmond, D.L.1    Knox, D.P.2
  • 43
    • 0027332107 scopus 로고
    • Haemonchus contortus: Identification of proteases with diverse characteristics in adult worm excretory-secretory products
    • Karanu FN, Rurangirwa FR, McGuire TC et al. Haemonchus contortus: identification of proteases with diverse characteristics in adult worm excretory-secretory products. Exp Parasitol 1993; 77:362-371
    • (1993) Exp Parasitol , vol.77 , pp. 362-371
    • Karanu, F.N.1    Rurangirwa, F.R.2    McGuire, T.C.3
  • 44
    • 0031148845 scopus 로고    scopus 로고
    • Haemonchus contortus: Inter- and intrageographic isolate heterogeneity of proteases in adult worm excretory-secretory products
    • Karanu FN, Rurangirwa FR, McGuire TC et al. Haemonchus contortus: inter- and intrageographic isolate heterogeneity of proteases in adult worm excretory-secretory products. Exp Parasitol 1997; 86:89-91
    • (1997) Exp Parasitol , vol.86 , pp. 89-91
    • Karanu, F.N.1    Rurangirwa, F.R.2    McGuire, T.C.3
  • 45
    • 0035951780 scopus 로고    scopus 로고
    • Cathepsin B-like cysteine proteases confer intestinal cysteine protease activity in Haemonchus contortus
    • Shompole S, Jasmer DP. Cathepsin B-like cysteine proteases confer intestinal cysteine protease activity in Haemonchus contortus. J Biol Chem 2001:276:2928-2934
    • (2001) J Biol Chem , vol.276 , pp. 2928-2934
    • Shompole, S.1    Jasmer, D.P.2
  • 46
    • 2542498963 scopus 로고    scopus 로고
    • Genetic variability in cysteine protease genes of Haemonchus contortus
    • Ruiz A, Molina JM, Njue A et al. Genetic variability in cysteine protease genes of Haemonchus contortus. Parasitology 2004; 128:549-559
    • (2004) Parasitology , vol.128 , pp. 549-559
    • Ruiz, A.1    Molina, J.M.2    Njue, A.3
  • 47
    • 0032811124 scopus 로고    scopus 로고
    • Defined characteristics of cathepsin B-like proteins from nematodes: Inferred functional diversity and phylogenetic relationships
    • Rehman A, Jasmer DP. Defined characteristics of cathepsin B-like proteins from nematodes: inferred functional diversity and phylogenetic relationships. Mol Biochem Parasitol 1999; 102:297-310
    • (1999) Mol Biochem Parasitol , vol.102 , pp. 297-310
    • Rehman, A.1    Jasmer, D.P.2
  • 48
    • 4644337865 scopus 로고    scopus 로고
    • MRNA sequences for Haemonchus contortus intestinal cathepsin B-like cysteine proteases display an extreme in abundance and diversity compared with other adult mammalian parasitic nematodes
    • Jasmer DP, Mitreva MD, McCarter JP. mRNA sequences for Haemonchus contortus intestinal cathepsin B-like cysteine proteases display an extreme in abundance and diversity compared with other adult mammalian parasitic nematodes. Mol Biochem Parasitol 2004; 137:297-305
    • (2004) Mol Biochem Parasitol , vol.137 , pp. 297-305
    • Jasmer, D.P.1    Mitreva, M.D.2    McCarter, J.P.3
  • 49
    • 33644774003 scopus 로고    scopus 로고
    • Identification of secreted cysteine proteases from the parasitic nematode Haemonchus contortus detected by biotinylated inhibitors
    • Yatsuda AP, Bakker N, Krijgsveld J et al. Identification of secreted cysteine proteases from the parasitic nematode Haemonchus contortus detected by biotinylated inhibitors. Infect Immun 2006; 74:1989-1993
    • (2006) Infect Immun , vol.74 , pp. 1989-1993
    • Yatsuda, A.P.1    Bakker, N.2    Krijgsveld, J.3
  • 50
    • 1642493623 scopus 로고    scopus 로고
    • Vaccination against the nematode Haemonchus contortus with a thiol-binding fraction from the excretory/secretory products (ES)
    • Bakker N, Vervelde L, Kanobana K et al. Vaccination against the nematode Haemonchus contortus with a thiol-binding fraction from the excretory/secretory products (ES). Vaccine 2004; 22:618-628
    • (2004) Vaccine , vol.22 , pp. 618-628
    • Bakker, N.1    Vervelde, L.2    Kanobana, K.3
  • 51
    • 67650705620 scopus 로고    scopus 로고
    • An AC-5 cathepsin B-like protease purified from Haemonchus contortus excretory secretory products shows protective antigen potential for lambs
    • De Vries E, Bakker N, Krijgsveld J et al. An AC-5 cathepsin B-like protease purified from Haemonchus contortus excretory secretory products shows protective antigen potential for lambs. Vet Res 2009; 40:41
    • (2009) Vet Res , vol.40 , pp. 41
    • De Vries, E.1    Bakker, N.2    Krijgsveld, J.3
  • 52
    • 0036628339 scopus 로고    scopus 로고
    • A novel cathepsin B active site motif is shared by helminth bloodfeeders
    • Baig S, Damian RT, Peterson DS. A novel cathepsin B active site motif is shared by helminth bloodfeeders. Exp Parasitol 2002; 101:83-89
    • (2002) Exp Parasitol , vol.101 , pp. 83-89
    • Baig, S.1    Damian, R.T.2    Peterson, D.S.3
  • 53
    • 0030026910 scopus 로고    scopus 로고
    • Isolation and characterization of four developmentally regulated cathepsin B-like cysteine protease genes from the nematode Caenorhabditis elegans
    • Larminie CG, Johnstone IL. Isolation and characterization of four developmentally regulated cathepsin B-like cysteine protease genes from the nematode Caenorhabditis elegans. DNA Cell Biol 1996; 15:75-82
    • (1996) DNA Cell Biol , vol.15 , pp. 75-82
    • Larminie, C.G.1    Johnstone, I.L.2
  • 54
    • 0034883828 scopus 로고    scopus 로고
    • Cathepsin B-like cysteine proteases and Caenorhabditis elegans homologues dominate gene products expressed in adult Haemonchus contortus intestine
    • Jasmer DP, Roth J, Myler PJ. Cathepsin B-like cysteine proteases and Caenorhabditis elegans homologues dominate gene products expressed in adult Haemonchus contortus intestine. Mol Biochem Parasitol 2001; 116:159-169
    • (2001) Mol Biochem Parasitol , vol.116 , pp. 159-169
    • Jasmer, D.P.1    Roth, J.2    Myler, P.J.3
  • 55
    • 28044458583 scopus 로고    scopus 로고
    • Combinatorial RNAi on intestinal cathepsin B-like proteinases in Caenorhabditis elegans questions the perception oftheir role in nematode biology
    • Geldhof P, Molloy C, Knox DP. Combinatorial RNAi on intestinal cathepsin B-like proteinases in Caenorhabditis elegans questions the perception oftheir role in nematode biology. Mol Biochem Parasitol 2006; 145:128-132
    • (2006) Mol Biochem Parasitol , vol.145 , pp. 128-132
    • Geldhof, P.1    Molloy, C.2    Knox, D.P.3
  • 56
    • 59349096661 scopus 로고    scopus 로고
    • The enigmatic asparaginyl endopeptidase of helminth parasites
    • Dalton JP, Brindley PJ, Donnelly S et al. The enigmatic asparaginyl endopeptidase of helminth parasites. Trends Parasitol 2009; 25:59-61
    • (2009) Trends Parasitol , vol.25 , pp. 59-61
    • Dalton, J.P.1    Brindley, P.J.2    Donnelly, S.3
  • 57
    • 33746238440 scopus 로고    scopus 로고
    • Identification and characterization of an asparaginyl proteinase (legumain) from the parasitic nematode, Haemonchus contortus
    • Oliver EM, Skuce PJ, McNair CM et al. Identification and characterization of an asparaginyl proteinase (legumain) from the parasitic nematode, Haemonchus contortus. Parasitology 2006; 133:237-244
    • (2006) Parasitology , vol.133 , pp. 237-244
    • Oliver, E.M.1    Skuce, P.J.2    McNair, C.M.3
  • 58
    • 53349174410 scopus 로고    scopus 로고
    • The intestinal contortin structure in Haemonchus contortus: An Immobilised Anticoagulant?
    • GeldhofP, Knox D. The intestinal contortin structure in Haemonchus contortus: An immobilised anticoagulant? Int J Parasitol 2008; 38:1579-1588
    • (2008) Int J Parasitol , vol.38 , pp. 1579-1588
    • Geldhofp Knox, D.1
  • 59
    • 0026445849 scopus 로고    scopus 로고
    • Isolation of putative cysteine protease genes of Ostertagia ostertagi
    • Pratt D, Boisvenue RJ, Cox GN. Isolation of putative cysteine protease genes of Ostertagia ostertagi. Mol Biochem Parasitol 1992; 56:39-48
    • Mol Biochem Parasitol , vol.1992 , Issue.56 , pp. 39-48
    • Pratt, D.1    Boisvenue, R.J.2    Cox, G.N.3
  • 60
    • 0036277631 scopus 로고    scopus 로고
    • Vaccination of calves against Ostertagia ostertagi with cysteine proteinase enriched protein fractions
    • Geldhof P, Claerebout E, Knox D et al. Vaccination of calves against Ostertagia ostertagi with cysteine proteinase enriched protein fractions. Parasite Immunol 2002; 24:263-270
    • (2002) Parasite Immunol , vol.24 , pp. 263-270
    • Geldhof, P.1    Claerebout, E.2    Knox, D.3
  • 61
    • 34848896640 scopus 로고    scopus 로고
    • Vaccination against Ostertagia ostertagi with subtractions of the protective ES-thiol fraction
    • Meyvis Y, Geldhof P, Gevaert K et al. Vaccination against Ostertagia ostertagi with subtractions of the protective ES-thiol fraction. Vet Parasitol 2007; 149:239-245
    • (2007) Vet Parasitol , vol.149 , pp. 239-245
    • Meyvis, Y.1    Geldhof, P.2    Gevaert, K.3
  • 62
    • 84961005926 scopus 로고
    • Proteolytic activity in extracts of the esophagus of adults of Ancylostoma caninum and the effect of immune serum on this activity
    • Thorson RE. Proteolytic activity in extracts of the esophagus of adults of Ancylostoma caninum and the effect of immune serum on this activity. J Parasitol 1956:42:21-25
    • (1956) J Parasitol , vol.42 , pp. 21-25
    • Thorson, R.E.1
  • 63
    • 0013954778 scopus 로고
    • Nature of an anticoagulant from the cephalic glands of Ancylostoma caninum
    • Eiff JA. Nature of an anticoagulant from the cephalic glands of Ancylostoma caninum. J Parasitol 1966; 52:833-843
    • (1966) J Parasitol , vol.52 , pp. 833-843
    • Eiff, J.A.1
  • 64
    • 0015043921 scopus 로고
    • Nossel HL Anticoagulant activity of dog hookworm
    • Spellman GG Jr, Nossel HL Anticoagulant activity of dog hookworm. Am J Physiol 1971; 220:922-927
    • (1971) Am J Physiol , vol.220 , pp. 922-927
    • Spellman Jr., G.G.1
  • 65
    • 0020608172 scopus 로고
    • Secretion of a proteolytic anticoagulant by Ancylostoma hookworms
    • Hotez PJ, Cerami A. Secretion of a proteolytic anticoagulant by Ancylostoma hookworms. J Exp Med 1983; 157:1594-1603
    • (1983) J Exp Med , vol.157 , pp. 1594-1603
    • Hotez, P.J.1    Cerami, A.2
  • 66
    • 0021831777 scopus 로고
    • Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum
    • Hotez PJ, Trang NL, McKerrow JH et al. Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum. J Biol Chem 1985; 260:7343-7348
    • (1985) J Biol Chem , vol.260 , pp. 7343-7348
    • Hotez, P.J.1    Trang, N.L.2    McKerrow, J.H.3
  • 67
    • 0028937046 scopus 로고
    • Ancylostoma caninum: Metalloprotease release coincides with activation of infective larvae in vitro
    • Hawdon JM, Jones BF, Perregaux MA et al. Ancylostoma caninum: metalloprotease release coincides with activation of infective larvae in vitro. Exp Parasitol 1995; 80:205-211
    • (1995) Exp Parasitol , vol.80 , pp. 205-211
    • Hawdon, J.M.1    Jones, B.F.2    Perregaux, M.A.3
  • 68
    • 0025607058 scopus 로고
    • Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis
    • Hotez P, Haggerty J, Hawdon J et al. Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis. Infect Immun 1990; 58:3883-3892
    • (1990) Infect Immun , vol.58 , pp. 3883-3892
    • Hotez, P.1    Haggerty, J.2    Hawdon, J.3
  • 69
    • 0026484149 scopus 로고
    • Secretion of metalloproteases by living infective larvae of Necator americanus
    • Kumar S, Pritchard DI Secretion of metalloproteases by living infective larvae of Necator americanus. J Parasitol 1992; 78:917-919
    • (1992) J Parasitol , vol.78 , pp. 917-919
    • Kumar, S.1    Pritchard, D.I.2
  • 70
    • 0034547887 scopus 로고    scopus 로고
    • Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo
    • Culley FJ, Brown A, Conroy DM et al. Eotaxin is specifically cleaved by hookworm metalloproteases preventing its action in vitro and in vivo. J Immunol 2000; 165:6447-6453
    • (2000) J Immunol , vol.165 , pp. 6447-6453
    • Culley, F.J.1    Brown, A.2    Conroy, D.M.3
  • 71
    • 0028029313 scopus 로고
    • Secretion of cysteine proteinase activity by the zoonotic hookworm Ancylostoma caninum
    • Dowd AJ, Dalton JP, Loukas AC et al. Secretion of cysteine proteinase activity by the zoonotic hookworm Ancylostoma caninum. Am J Trop Med Hyg 1994; 51:341-347
    • (1994) Am J Trop Med Hyg , vol.51 , pp. 341-347
    • Dowd, A.J.1    Dalton, J.P.2    Loukas, A.C.3
  • 72
    • 0029069029 scopus 로고
    • Characterization and localization of cathepsin B proteinases expressed by adult Ancylostoma caninum hookworms
    • Harrop SA, Sawangjaroen N, Prociv P et al. Characterization and localization of cathepsin B proteinases expressed by adult Ancylostoma caninum hookworms. Mol Biochem Parasitol 1995; 71:163-171
    • (1995) Mol Biochem Parasitol , vol.71 , pp. 163-171
    • Harrop, S.A.1    Sawangjaroen, N.2    Prociv, P.3
  • 73
    • 0029822501 scopus 로고    scopus 로고
    • Structural analysis of the catalytic site of AcCP-1, a cysteine proteinase secreted by the hookworm Ancylostoma caninum
    • Brinkworth RI, Brindley PJ, Harrop SA. Structural analysis of the catalytic site of AcCP-1, a cysteine proteinase secreted by the hookworm Ancylostoma caninum. Biochim Biophys Acta 1996:1298:4-8
    • (1996) Biochim Biophys Acta , vol.1298 , pp. 4-8
    • Brinkworth, R.I.1    Brindley, P.J.2    Harrop, S.A.3
  • 74
    • 2442680125 scopus 로고    scopus 로고
    • Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms
    • Loukas A, Bethony JM, Williamson AL et al. Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms. J Infect Dis 2004; 189:1952-1961
    • (2004) J Infect Dis , vol.189 , pp. 1952-1961
    • Loukas, A.1    Bethony, J.M.2    Williamson, A.L.3
  • 75
    • 50049136204 scopus 로고    scopus 로고
    • A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus
    • Ranjit N, Zhan B, Stenzel DJ et al. A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Mol Biochem Parasitol 2008; 160:90-99
    • (2008) Mol Biochem Parasitol , vol.160 , pp. 90-99
    • Ranjit, N.1    Zhan, B.2    Stenzel, D.J.3
  • 76
    • 0141632879 scopus 로고    scopus 로고
    • Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae
    • Hotez PJ, Ashcom J, Zhan B et al. Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae. J Parasitol 2003; 89:853-855
    • (2003) J Parasitol , vol.89 , pp. 853-855
    • Hotez, P.J.1    Ashcom, J.2    Zhan, B.3
  • 77
    • 27644550925 scopus 로고    scopus 로고
    • Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs
    • Loukas A, Bethony JM, Mendez S et al. Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. PLoS Med 2005; 2:e295
    • (2005) PLoS Med , vol.2
    • Loukas, A.1    Bethony, J.M.2    Mendez, S.3
  • 78
    • 70349324805 scopus 로고    scopus 로고
    • An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection
    • Pearson MS, Bethony JM, Pickering DA et al. An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB J 2009; 23:3007-3019
    • (2009) FASEB J , vol.23 , pp. 3007-3019
    • Pearson, M.S.1    Bethony, J.M.2    Pickering, D.A.3
  • 79
    • 77951908006 scopus 로고    scopus 로고
    • Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: Implications for a multivalent vaccine against hookworm infection and schistosomiasis
    • Pearson MS, Pickering DA, Tribolet L et al. Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis. J Infect Dis 2010; 201:1561-1569
    • (2010) J Infect Dis , vol.201 , pp. 1561-1569
    • Pearson, M.S.1    Pickering, D.A.2    Tribolet, L.3
  • 80
    • 49449092450 scopus 로고    scopus 로고
    • A Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis
    • Hotez PJ, Bethony JM, Oliveira SC et al. A. Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Exp Rev Vaccines 2008; 7:745-752
    • (2008) Exp Rev Vaccines , vol.7 , pp. 745-752
    • Hotez, P.J.1    Bethony, J.M.2    Oliveira, S.C.3
  • 81
    • 0036139151 scopus 로고    scopus 로고
    • Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms
    • Jones BF, Hotez PJ. Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Mol Biochem Parasitol 2002; 119:107-116
    • (2002) Mol Biochem Parasitol , vol.119 , pp. 107-116
    • Jones, B.F.1    Hotez, P.J.2
  • 82
    • 0036718532 scopus 로고    scopus 로고
    • Cleavage ofhemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity
    • Williamson AL, Brindley PJ, Abbenante G et al. Cleavage ofhemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity FASEB J 2002; 16 :1458-1460
    • (2002) FASEB J , vol.16 , pp. 1458-1460
    • Williamson, A.L.1    Brindley, P.J.2    Abbenante, G.3
  • 83
    • 0037312504 scopus 로고    scopus 로고
    • Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion
    • Williamson AL, Brindley PJ, Abbenante G et al. Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. J Infect Dis 2003; 187:484-494
    • (2003) J Infect Dis , vol.187 , pp. 484-494
    • Williamson, A.L.1    Brindley, P.J.2    Abbenante, G.3
  • 84
    • 0345118193 scopus 로고    scopus 로고
    • Hookworm cathepsin D aspartic proteases: Contributing roles in the host-specific degradation of serum proteins and skin macromolecules
    • Williamson AL, Brindley PJ, Loukas A. Hookworm cathepsin D aspartic proteases: contributing roles in the host-specific degradation of serum proteins and skin macromolecules. Parasitology 2003; 126:179-185
    • (2003) Parasitology , vol.126 , pp. 179-185
    • Williamson, A.L.1    Brindley, P.J.2    Loukas, A.3
  • 85
    • 0028211978 scopus 로고
    • Order and specificity ofthe Plasmodium falciparum hemoglobin degradation pathway
    • Gluzman IY, Francis SE, Oksman A et al. Order and specificity ofthe Plasmodium falciparum hemoglobin degradation pathway. J Clin Invest 1994; 93:1602-1608
    • (1994) J Clin Invest , vol.93 , pp. 1602-1608
    • Gluzman, I.Y.1    Francis, S.E.2    Oksman, A.3
  • 86
    • 65649122615 scopus 로고    scopus 로고
    • Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus
    • Ranjit N, Zhan B, Hamilton B et al. Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus. J Infect Dis 2009; 199:904-912
    • (2009) J Infect Dis , vol.199 , pp. 904-912
    • Ranjit, N.1    Zhan, B.2    Hamilton, B.3
  • 87
    • 0037046107 scopus 로고    scopus 로고
    • A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases
    • Zhan B, Hotez PJ, Wang Y et al. A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases. Mol Biochem Parasitol 2002; 120:291-296
    • (2002) Mol Biochem Parasitol , vol.120 , pp. 291-296
    • Zhan, B.1    Hotez, P.J.2    Wang, Y.3
  • 88
    • 0029016839 scopus 로고
    • The astacin family of metalloendopeptidases
    • Bond JS, Beynon RJ. The astacin family of metalloendopeptidases. Protein Sci 1995; 4:1247-1261
    • (1995) Protein Sci , vol.4 , pp. 1247-1261
    • Bond, J.S.1    Beynon, R.J.2
  • 89
    • 0141632879 scopus 로고    scopus 로고
    • Effect of vaccination with a recombinant fusion protein encoding an astacin-like metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae
    • Hotez PJ, Ashcom J, Zhan B et al. Effect of vaccination with a recombinant fusion protein encoding an astacin-like metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae. J Parasitol 2003; 89:853-855
    • (2003) J Parasitol , vol.89 , pp. 853-855
    • Hotez, P.J.1    Ashcom, J.2    Zhan, B.3
  • 90
    • 20144387080 scopus 로고    scopus 로고
    • Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum
    • Mendez S, Zhan B, Goud G et al. Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine 2005; 23:3123-3130
    • (2005) Vaccine , vol.23 , pp. 3123-3130
    • Mendez, S.1    Zhan, B.2    Goud, G.3
  • 91
    • 33847258857 scopus 로고    scopus 로고
    • Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum
    • Feng J, Zhan B, Liu Y et al. Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum. Mol Biochem Parasitol 2007; 152:132-138
    • (2007) Mol Biochem Parasitol , vol.152 , pp. 132-138
    • Feng, J.1    Zhan, B.2    Liu, Y.3
  • 92
    • 0035071090 scopus 로고    scopus 로고
    • Characterisation of Haemonchus contortus-derived cell populations propagated in vitro in a tissue culture environment and their potential to induce protective immunity in sheep
    • Coyne CP, Brake D. Characterisation of Haemonchus contortus-derived cell populations propagated in vitro in a tissue culture environment and their potential to induce protective immunity in sheep. Int J Parasitol 2001; 31:359-376
    • (2001) Int J Parasitol , vol.31 , pp. 359-376
    • Coyne, C.P.1    Brake, D.2
  • 93
    • 77952261552 scopus 로고    scopus 로고
    • Attempts to immunize sheep against Haemonchus contortus using a cocktail of recombinant proteases derived from the protective antigen, H-gal-GP
    • Cachat E, Newlands GF, Ekoja SE et al. Attempts to immunize sheep against Haemonchus contortus using a cocktail of recombinant proteases derived from the protective antigen, H-gal-GP. Parasite Immunol 2010; 32:414-419
    • (2010) Parasite Immunol , vol.32 , pp. 414-419
    • Cachat, E.1    Newlands, G.F.2    Ekoja, S.E.3
  • 94
    • 34447303347 scopus 로고    scopus 로고
    • Expression and purification of an active cysteine protease ofHaemonchus contortus using Caenorhabditis elegans
    • Murray L, GeldhofP, Clark D et al. Expression and purification of an active cysteine protease ofHaemonchus contortus using Caenorhabditis elegans. Int J Parasitol 2007; 37:1117-1125
    • (2007) Int J Parasitol , vol.37 , pp. 1117-1125
    • Murray, L.1    Geldhofp Clark, D.2
  • 95
    • 54349101052 scopus 로고    scopus 로고
    • Induction of immunity in sheep to Fasciola hepatica with mimotopes of cathepsin L selected from a phage display library
    • Villa-Mancera A, Quiroz-Romero H, Correa D et al. Induction of immunity in sheep to Fasciola hepatica with mimotopes of cathepsin L selected from a phage display library. Parasitology 2008; 135:1437-1445
    • (2008) Parasitology , vol.135 , pp. 1437-1445
    • Villa-Mancera, A.1    Quiroz-Romero, H.2    Correa, D.3
  • 96
    • 0038725897 scopus 로고    scopus 로고
    • Genome-wide RNAi screening in Caenorhabditis elegans
    • Kamath RS, Ahringer J. Genome-wide RNAi screening in Caenorhabditis elegans. Methods 2003; 30:313-321
    • (2003) Methods , vol.30 , pp. 313-321
    • Kamath, R.S.1    Ahringer, J.2
  • 97
    • 33745009743 scopus 로고    scopus 로고
    • Testing the efficacy of RNA interference in Haemonchus contortus
    • GeldhofP, Murray L, Couthier A et al. Testing the efficacy of RNA interference in Haemonchus contortus. Int J Parasitol 2006; 36:801-810
    • (2006) Int J Parasitol , vol.36 , pp. 801-810
    • Geldhofp Murray, L.1    Couthier, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.