The development of vaccines against gastrointestinal nematode parasites, particularly Haemonchus contortus

Parasitology Today

Volumn 15, Issue 3, 1999, Pages 116-122

  Newton, Sue E ^a   Munn, E A ^b  

^a VIC INSTITUTE OF ANIMAL SCIENCE   (Australia)

^b BABRAHAM INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHELMINTIC AGENT; PARASITE ANTIGEN; VACCINE;

GASTROINTESTINAL INFECTION; GOAT; HAEMONCHUS CONTORTUS; HUMAN; IMMUNE RESPONSE; IMMUNITY; NEMATODIASIS; NONHUMAN; PARASITE CONTROL; REVIEW; SHEEP; VACCINATION;

ANIMALS; ANTIGENS, HELMINTH; DIGESTIVE SYSTEM; HAEMONCHIASIS; HAEMONCHUS; HUMANS; INTESTINAL DISEASES, PARASITIC; NEMATODA; NEMATODE INFECTIONS; VACCINES;

CAPRA HIRCUS; HAEMONCHUS CONTORTUS; NEMATODA; OVIS ARIES;

EID: 0033102205     PISSN: 01694758     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-4758(99)01399-X     Document Type: Review

References (66)

1. Waller P.J.et al. The prevalence of anthelmintic resistance in nematode parasites of sheep in Southern Latin America - general overview. Vet. Parasitol. 62:1996;181-187.
2. van Wyk J.A.et al. How long before resistance makes it impossible to control some field strains of Haemonchus contortus in South Africa with any of the modern anthelmintics? Vet. Parasitol. 70:1997;111-122.
3. Smith T.S., Munn E.A. Strategies for vaccination against gastrointestinal nematodes. Rev. Sci. Tech. Off. Int. Epiz. 9:1990;577-595.
4. Emery D.L., Wagland B.M. Vaccines against gastrointestinal nematode parasites of ruminants. Parasitol. Today. 7:1991;347-349.
5. Munn E.A. Rational design of nematode vaccines: hidden antigens. Int. J. Parasitol. 27:1997;359-366.
6. Peacock R., Poynter D. Field experience with a bovine lungworm vaccine. Symp. Br. Soc. Parasitol. 18:1980;141-148.
7. Johnson K.S.et al. Vaccination against ovine cysticercosis using a defined recombinant antigen. Nature. 338:1989;585-587.
8. Harrison G.B.L.et al. Identification and cDNA cloning of two novel low molecular weight host-protective antigens from Taenia ovis oncospheres. Int. J. Parasitol. 26:1996;195-204.
9. Rickard M.D.et al. Taenia ovis recombinant vaccine - 'quo vadit'. Parasitology. 110:1995;S5-S9.
10. Emery D.L.et al. Production of vaccines against gastrointestinal nematodes of livestock. Immunol. Cell Biol. 71:1993;463-472.
11. Emery D.L. Vaccination against worm parasites of animals. Vet. Parasitol. 64:1996;31-45.
12. Smith W.D., Angus K.W. Haemonchus contortus: attempts to immunise lambs with irradiated larvae. Res. Vet. Sci. 29:1980;45-50.
13. Neilson J.T.M., van de Walle M.J. Partial protection of lambs against Haemonchus contortus by vaccination with a fractionated preparation of the parasite. Vet. Parasitol. 23:1987;211-221.
14. Smith W.D. Serum and mucus antibodies in sheep immunised with larval antigens of Haemonchus contortus. Res. Vet. Sci. 22:1977;128-129.
15. Meeusen E.et al. Lymphocyte subpopulations of sheep in protective immunity to Taenia hydatigena. Parasite Immunol. 11:1989;169-181.
16. Meeusen E.et al. Cysticercosis: cellular immune responses during primary and secondary infection. Parasite Immunol. 12:1990;403-418.
17. Lee C.S.et al. Local immunity in the mammary gland. Vet. Immunol. Immunopathol. 32:1992;1-11.
18. Meeusen E.N.T., Brandon M.R. Antibody secreting cells as specific probes for antigen identification. J. Immunol. Methods. 172:1994;71-76.
19. Meeusen E.N.T. Rational design of nematode vaccines: natural antigens. Int. J. Parasitol. 26:1996;813-818.
20. Bowles V.M.et al. Characterization of local antibody responses to the gastrointestinal parasite Haemonchus contortus. Immunology. 84:1995;669-674.
21. Jacobs H.J.et al. Vaccination against the gastrointestinal nematode Haemonchus contortus using a purified larval surface antigen. Vaccine. 17:1999;362-368.
22. Raleigh J.M.et al. Stage-specific expression of surface molecules by the larval stages of Haemonchus contortus. Parasite Immunol. 18:1996;125-132.
23. Raleigh J.M., Meeusen E.N.T. Developmentally regulated expression of a Haemonchus contortus surface antigen. Int. J. Parasitol. 26:1996;673-675.
24. Ashman K.et al. Isolation of a larval surface glycoprotein from Haemonchus contortus and its possible role in evading host immunity. Mol. Biochem. Parasitol. 70:1995;175-179.
25. Jacobs H.J.et al. Humoral and cellular responses following local immunization with a surface antigen of the gastrointestinal parasite Haemonchus contortus. Vet. Immunol. Immunopathol. 48:1995;323-332.
26. Cox J.C., Coulter A.R. Adjuvants - a classification and review of their modes of action. Vaccine. 15:1997;248-256.
27. Nash A.D.et al. Recombinant cytokines as immunological adjuvants. Immunol. Cell Biol. 71:1993;367-379.
28. Turnbull I.F.et al. Systemic immunization of sheep with surface antigens from Haemonchus contortus larvae. Int. J. Parasitol. 22:1992;537-540.
29. Grencis R.K. T cell and cytokine basis of host variability in response to intestinal nematode infections. Parasitology. 112:1996;S31-S37.
30. Rainbird M.A.et al. Eosinophil-mediated killing of Haemonchus contortus larvae: effect of eosinophil activation and role of antibody, complement and interleukin-5. Parasite Immunol. 20:1998;93-103.
31. Buddle B.M.et al. Association of blood eosinophilia with the expression of resistance in Romney lambs to nematodes. Int. J. Parasitol. 22:1992;955-960.
32. Meeusen, E.N.T. et al. (1995) Production of antigens. Patent No. WO 95/09182.
33. Newton S.E.et al. cDNA cloning of galectins from third stage larvae of the parasitic nematode Teladorsagia circumcincta. Mol. Biochem. Parasitol. 86:1997;143-153.
34. Greenhalgh, C.J. et al. Galectins from sheep gastrointestinal nematode parasites are highly conserved. Mol. Biochem. Parasitol. (in press).
35. Schallig H.D.F.H.et al. Immune responses of Texel sheep to excretory/secretory products of adult Haemonchus contortus. Parasitology. 108:1994;351-357.
36. Schallig H.D.F.H., van Leeuwen M.A.W. Protective immunity to the blood-feeding nematode Haemonchus contortus induced by vaccination with parasite low molecular weight antigens. Parasitology. 114:1997;293-299.
37. Schallig H.D.F.H.et al. Protective immunity induced by vaccination with two Haemonchus contortus excretory secretory proteins in sheep. Parasite Immunol. 19:1997;447-453.
38. Schallig H.D.F.H.et al. Molecular characterization and expression of two putative protective excretory secretory proteins of Haemonchus contortus. Mol. Biochem. Parasitol. 88:1997;203-213.
39. Willadsen P. Novel vaccines for ectoparasites. Vet. Parasitol. 71:1997;209-222.
40. Newton S.E. Progress on vaccination against Haemonchus contortus. Int. J. Parasitol. 25:1995;1281-1289.
41. Tellam R.L., Bowles V.M. Control of blowfly strike in sheep: current strategies and future prospects. Int. J. Parasitol. 27:1997;261-273.
42. Jarmey J.M.et al. Carboxydipeptidase from Boophilus microplus: a 'concealed' antigen with similarity to angiotensin-converting enzyme. Insect Biochem. Mol. Biol. 25:1995;969-974.
43. Willadsen P.et al. Comparative vaccination of cattle against Boophilus microplus with recombinant antigen Bm86 alone or in combination with recombinant Bm91. Parasite Immunol. 18:1996;214-246.
44. Munn E.A. A helical, polymeric extracellular protein associated with the luminal surface of Haemonchus contortus intestinal cells. Tissue Cell. 9:1977;23-34.
45. Munn E.A.et al. Vaccination of young lambs by means of a protein fraction extracted from adult Haemonchus contortus. Parasitology. 94:1987;385-397.
46. Smith T.S.et al. Cloning and characterization of a microsomal aminopeptidase from the intestine of the nematode Haemonchus contortus. Biochim. Biophys. Acta. 1338:1997;295-306.
47. Graham, M. et al. (1993) Recombinant DNA molecules encoding aminopeptidase enzymes and their use in the preparation of vaccines against helminth infections. Patent No. WO 93/23542.
48. Andrews S.J.et al. Duration of protective immunity against ovine haemonchosis following vaccination with the nematode gut membrane antigen H11. Res. Vet. Sci. 62:1997;223-227.
49. Andrews S.J.et al. Vaccination of sheep against haemonchosis with H11, a gut membrane-derived protective antigen from the adult parasite: prevention of the periparturient rise and colostral transfer of protective immunity. Int. J. Parasitol. 25:1995;839-846.
50. Smith W.D., Smith S.K. Evaluation of aspects of the protection afforded to sheep immunised with a gut membrane protein of Haemonchus contortus. Res. Vet. Sci. 55:1993;1-9.
51. Tavernor A.S.et al. Immune response of Clun Forest sheep to vaccination with membrane glycoproteins from Haemonchus contortus. Parasite Immunol. 14:1992;671-675.
52. Munn E.A.et al. Vaccination against Haemonchus contortus with denatured forms of the protective antigen H11. Parasite Immunol. 19:1997;243-248.
53. Smith W.D.et al. Protection studies with integral membrane fractions of Haemonchus contortus. Parasite Immunol. 16:1994;231-241.
54. Redmond D.L.et al. Molecular cloning and characterisation of a developmentally regulated putative metallopeptidase present in a host protective extract of Haemonchus contortus. Mol. Biochem. Parasitol. 85:1997;77-87.
55. Longbottom D.et al. Molecular cloning and characterisation of a putative aspartate proteinase associated with a gut membrane protein complex from adult Haemonchus contortus. Mol. Biochem. Parasitol. 88:1997;63-72.
56. Smith S.K., Smith W.D. Immunisation of sheep with an integral membrane glycoprotein complex of Haemonchus contortus and with its major polypeptide components. Res. Vet. Sci. 60:1996;1-6.
57. Jasmer D.P.et al. Protective immunity to Haemonchus contortus induced by immunoaffinity isolated antigens that share a phylogenetically conserved carbohydrate gut surface epitope. J. Immunol. 151:1993;5450-5460.
58. Jasmer D.P.et al. Haemonchus contortus GA1 antigens: related, phospholipase C-sensitive, apical gut membrane proteins encoded as a polyprotein and released from the nematode during infection. Proc. Natl. Acad. Sci. U. S. A. 93:1996;8642-8647.
59. Smith T.S.et al. Purification and evaluation of the integral membrane protein H11 as a protective antigen against Haemonchus contortus. Int. J. Parasitol. 23:1993;271-280.
60. Cox G.N.et al. Molecular cloning and primary sequence of a cysteine protease expressed by Haemonchus contortus adult worms. Mol. Biochem. Parasitol. 41:1990;25-34.
61. Boisvenue R.J.et al. Fibrinogen-degrading proteins from Haemonchus contortus used to vaccinate sheep. Am. J. Vet. Res. 53:1992;1263-1265.
62. Knox, D.P. et al. (1995) Vaccines against helminthic parasites. Patent No. WO 95/26402.
63. Munn E.A.et al. The potential value of integral membrane proteins in the vaccination of lambs against Haemonchus contortus. Int. J. Parasitol. 23:1993;261-269.
64. Munn E.A.et al. Vaccination of merino lambs against haemonchosis with membrane-associated proteins from the adult parasite. Parasitology. 106:1993;63-66.
65. Tavernor A.S.et al. Vaccination of young Dorset lambs against haemonchosis. Parasite Immunol. 14:1992;625-655.
66. Newton S.E.et al. Protection against multiply drug- resistant and geographically distant strains of Haemonchus contortus by vaccination with H11, a gut membrane-derived protective antigen. Int. J. Parasitol. 25:1995;511-521.