Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs

PLoS Medicine

Volumn 2, Issue 10, 2005, Pages 1008-1017

  Loukas, Alex ^a   Bethony, Jeffrey M ^b   Mendez, Susana ^b   Fujiwara, Ricardo T ^b   Goud, Gaddam Narsa ^b   Ranjit, Najju ^a   Zhan, Bin ^b   Jones, Karen ^b   Bottazzi, Maria Elena ^b   Hotez, Peter J ^b  

^a QIMR BERGHOFER MEDICAL RESEARCH INSTITUTE   (Australia)

^b GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME PRECURSOR; IMMUNOGLOBULIN G; RECOMBINANT ASPARTIC HEMOGLOBINASE; RECOMBINANT ENZYME; RECOMBINANT VACCINE; UNCLASSIFIED DRUG; ASPARTIC PROTEINASE; PLASMEPSIN; RECOMBINANT PROTEIN;

ANCYLOSTOMA CANINUM; ANEMIA; ARTICLE; BLEEDING; CATALYSIS; DISEASE COURSE; DOG; FECES ANALYSIS; HOOKWORM INFECTION; HUMAN; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IRON DEFICIENCY ANEMIA; PROTEIN DEGRADATION; REDUCTION; VACCINATION; AMINO ACID SEQUENCE; ANCYLOSTOMA; ANIMAL; ANIMAL DISEASE; ANTIBODY PRODUCTION; CLINICAL TRIAL; MALE; MOLECULAR GENETICS; PATHOGENICITY; PATHOLOGY;

AMINO ACID SEQUENCE; ANCYLOSTOMA; ANEMIA; ANIMALS; ANTIBODY FORMATION; ASPARTIC ACID ENDOPEPTIDASES; DOGS; HEMORRHAGE; HOOKWORM INFECTIONS; IMMUNOGLOBULIN G; MALE; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; VACCINATION;

EID: 27644550925     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.0020295     Document Type: Article

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