-
1
-
-
58149489177
-
Ovarian carcinoma subtypes are different diseases: implications for biomarker studies
-
Kobel M, Kalloger SE, Boyd N, et al. Ovarian carcinoma subtypes are different diseases: implications for biomarker studies. PLoS Med 2008, 5:e232.
-
(2008)
PLoS Med
, vol.5
-
-
Kobel, M.1
Kalloger, S.E.2
Boyd, N.3
-
2
-
-
56749103412
-
The cell of origin of ovarian epithelial tumours
-
Dubeau L The cell of origin of ovarian epithelial tumours. Lancet Oncol 2008, 9:1191-1197.
-
(2008)
Lancet Oncol
, vol.9
, pp. 1191-1197
-
-
Dubeau, L.1
-
3
-
-
55949089955
-
New insights into the pathogenesis of serous ovarian cancer and its clinical impact
-
Levanon K, Crum C, Drapkin R New insights into the pathogenesis of serous ovarian cancer and its clinical impact. J Clin Oncol 2008, 26:5284-5293.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5284-5293
-
-
Levanon, K.1
Crum, C.2
Drapkin, R.3
-
4
-
-
77950965840
-
Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
-
Ahmed AA, Etemadmoghadam D, Temple J, et al. Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary. J Pathol 2010, 221:49-56.
-
(2010)
J Pathol
, vol.221
, pp. 49-56
-
-
Ahmed, A.A.1
Etemadmoghadam, D.2
Temple, J.3
-
5
-
-
77957946398
-
ARID1A mutations in endometriosis-associated ovarian carcinomas
-
Wiegand KC, Shah SP, Al-Agha OM, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med 2010, 363:1532-1543.
-
(2010)
N Engl J Med
, vol.363
, pp. 1532-1543
-
-
Wiegand, K.C.1
Shah, S.P.2
Al-Agha, O.M.3
-
6
-
-
77950352170
-
Ovarian cancer: markers of response
-
Na YJ, Farley J, Zeh A, et al. Ovarian cancer: markers of response. Int J Gynecol Cancer 2009, 19(suppl 2):S21-S29.
-
(2009)
Int J Gynecol Cancer
, vol.19
, Issue.SUPPL. 2
-
-
Na, Y.J.1
Farley, J.2
Zeh, A.3
-
7
-
-
33645225423
-
The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome
-
Medeiros F, Muto MG, Lee Y, et al. The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol 2006, 30:230-236.
-
(2006)
Am J Surg Pathol
, vol.30
, pp. 230-236
-
-
Medeiros, F.1
Muto, M.G.2
Lee, Y.3
-
8
-
-
33750312322
-
Mechanisms of transcoelomic metastasis in ovarian cancer
-
Tan DS, Agarwal R, Kaye SB Mechanisms of transcoelomic metastasis in ovarian cancer. Lancet Oncol 2006, 7:925-934.
-
(2006)
Lancet Oncol
, vol.7
, pp. 925-934
-
-
Tan, D.S.1
Agarwal, R.2
Kaye, S.B.3
-
9
-
-
34548099690
-
High-resolution single nucleotide polymorphism array analysis of epithelial ovarian cancer reveals numerous microdeletions and amplifications
-
Gorringe KL, Jacobs S, Thompson ER, et al. High-resolution single nucleotide polymorphism array analysis of epithelial ovarian cancer reveals numerous microdeletions and amplifications. Clin Cancer Res 2007, 13:4731-4739.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4731-4739
-
-
Gorringe, K.L.1
Jacobs, S.2
Thompson, E.R.3
-
10
-
-
34548525798
-
Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction
-
Callahan MJ, Crum CP, Medeiros F, et al. Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction. J Clin Oncol 2007, 25:3985-3990.
-
(2007)
J Clin Oncol
, vol.25
, pp. 3985-3990
-
-
Callahan, M.J.1
Crum, C.P.2
Medeiros, F.3
-
11
-
-
0026517086
-
Responses to salvage chemotherapy in ovarian cancer: a critical need for precise definitions of the treated population
-
Markman M, Hoskins W Responses to salvage chemotherapy in ovarian cancer: a critical need for precise definitions of the treated population. J Clin Oncol 1992, 10:520-528.
-
(1992)
J Clin Oncol
, vol.10
, pp. 520-528
-
-
Markman, M.1
Hoskins, W.2
-
12
-
-
0032910470
-
Extending the platinum-free interval in recurrent ovarian cancer: the role of topotecan in second-line chemotherapy
-
Bookman MA Extending the platinum-free interval in recurrent ovarian cancer: the role of topotecan in second-line chemotherapy. Oncologist 1999, 4:87-94.
-
(1999)
Oncologist
, vol.4
, pp. 87-94
-
-
Bookman, M.A.1
-
13
-
-
0034604716
-
The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin
-
Bhattacharyya A, Ear US, Koller BH, et al. The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin. J Biol Chem 2000, 275:23899-23903.
-
(2000)
J Biol Chem
, vol.275
, pp. 23899-23903
-
-
Bhattacharyya, A.1
Ear, U.S.2
Koller, B.H.3
-
14
-
-
37849030476
-
Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer
-
Chetrit A, Hirsh-Yechezkel G, Ben-David Y, et al. Effect of BRCA1/2 mutations on long-term survival of patients with invasive ovarian cancer: the national Israeli study of ovarian cancer. J Clin Oncol 2008, 26:20-25.
-
(2008)
J Clin Oncol
, vol.26
, pp. 20-25
-
-
Chetrit, A.1
Hirsh-Yechezkel, G.2
Ben-David, Y.3
-
15
-
-
79955478110
-
Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer
-
Zhang S, Royer R, Li S, et al. Frequencies of BRCA1 and BRCA2 mutations among 1,342 unselected patients with invasive ovarian cancer. Gynecol Oncol 2011, 121:353-357.
-
(2011)
Gynecol Oncol
, vol.121
, pp. 353-357
-
-
Zhang, S.1
Royer, R.2
Li, S.3
-
16
-
-
0037169354
-
Cancer susceptibility and the functions of BRCA1 and BRCA2
-
Venkitaraman AR Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 2002, 108:171-182.
-
(2002)
Cell
, vol.108
, pp. 171-182
-
-
Venkitaraman, A.R.1
-
19
-
-
0038075462
-
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
-
Taniguchi T, Tischkowitz M, Ameziane N, et al. Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors. Nat Med 2003, 9:568-574.
-
(2003)
Nat Med
, vol.9
, pp. 568-574
-
-
Taniguchi, T.1
Tischkowitz, M.2
Ameziane, N.3
-
20
-
-
0028960025
-
Somatic mutations in the BRCA1 gene in sporadic ovarian tumours
-
Merajver SD, Pham TM, Caduff RF, et al. Somatic mutations in the BRCA1 gene in sporadic ovarian tumours. Nat Genet 1995, 9:439-443.
-
(1995)
Nat Genet
, vol.9
, pp. 439-443
-
-
Merajver, S.D.1
Pham, T.M.2
Caduff, R.F.3
-
21
-
-
0034607234
-
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors
-
Esteller M, Silva JM, Dominguez G, et al. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst 2000, 92:564-569.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 564-569
-
-
Esteller, M.1
Silva, J.M.2
Dominguez, G.3
-
22
-
-
42149144580
-
Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer
-
Lim SL, Smith P, Syed N, et al. Promoter hypermethylation of FANCF and outcome in advanced ovarian cancer. Br J Cancer 2008, 98:1452-1456.
-
(2008)
Br J Cancer
, vol.98
, pp. 1452-1456
-
-
Lim, S.L.1
Smith, P.2
Syed, N.3
-
23
-
-
10744233204
-
EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer
-
Hughes-Davies L, Huntsman D, Ruas M, et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer. Cell 2003, 115:523-535.
-
(2003)
Cell
, vol.115
, pp. 523-535
-
-
Hughes-Davies, L.1
Huntsman, D.2
Ruas, M.3
-
24
-
-
79959838081
-
Integrated genomic analyses of ovarian carcinoma
-
The Cancer Genome Atlas Research Network
-
Integrated genomic analyses of ovarian carcinoma. Nature 2011, 474:609-615. The Cancer Genome Atlas Research Network.
-
(2011)
Nature
, vol.474
, pp. 609-615
-
-
-
25
-
-
45749108933
-
How do real tumors become resistant to cisplatin?
-
Borst P, Rottenberg S, Jonkers J How do real tumors become resistant to cisplatin?. Cell Cycle 2008, 7:1353-1359.
-
(2008)
Cell Cycle
, vol.7
, pp. 1353-1359
-
-
Borst, P.1
Rottenberg, S.2
Jonkers, J.3
-
26
-
-
39849106300
-
Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers
-
Sakai W, Swisher EM, Karlan BY, et al. Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers. Nature 2008, 451:1116-1120.
-
(2008)
Nature
, vol.451
, pp. 1116-1120
-
-
Sakai, W.1
Swisher, E.M.2
Karlan, B.Y.3
-
27
-
-
42349096328
-
Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance
-
Swisher EM, Sakai W, Karlan BY, et al. Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance. Cancer Res 2008, 68:2581-2586.
-
(2008)
Cancer Res
, vol.68
, pp. 2581-2586
-
-
Swisher, E.M.1
Sakai, W.2
Karlan, B.Y.3
-
28
-
-
69249100461
-
Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma
-
Sakai W, Swisher EM, Jacquemont C, et al. Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma. Cancer Res 2009, 69:6381-6386.
-
(2009)
Cancer Res
, vol.69
, pp. 6381-6386
-
-
Sakai, W.1
Swisher, E.M.2
Jacquemont, C.3
-
29
-
-
34547504504
-
Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer
-
Rottenberg S, Nygren AO, Pajic M, et al. Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer. Proc Natl Acad Sci USA 2007, 104:12117-12122.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12117-12122
-
-
Rottenberg, S.1
Nygren, A.O.2
Pajic, M.3
-
30
-
-
0001641514
-
Mutations of bacteria from virus sensitivity to virus resistance
-
Luria SE, Delbruck M Mutations of bacteria from virus sensitivity to virus resistance. Genetics 1943, 28:491-511.
-
(1943)
Genetics
, vol.28
, pp. 491-511
-
-
Luria, S.E.1
Delbruck, M.2
-
31
-
-
33846693157
-
The role of spontaneous variants in the acquisition of streptomycin resistance by the shigellae
-
Klein M, Kimmelman LJ The role of spontaneous variants in the acquisition of streptomycin resistance by the shigellae. J Bacteriol 1946, 52:471-479.
-
(1946)
J Bacteriol
, vol.52
, pp. 471-479
-
-
Klein, M.1
Kimmelman, L.J.2
-
32
-
-
34547123580
-
Relapse in children with acute lymphoblastic leukemia involving selection of a preexisting drug-resistant subclone
-
Choi S, Henderson MJ, Kwan E, et al. Relapse in children with acute lymphoblastic leukemia involving selection of a preexisting drug-resistant subclone. Blood 2007, 110:632-639.
-
(2007)
Blood
, vol.110
, pp. 632-639
-
-
Choi, S.1
Henderson, M.J.2
Kwan, E.3
-
33
-
-
0001686739
-
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
-
Shah NP, Nicoll JM, Nagar B, et al. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell 2002, 2:117-125.
-
(2002)
Cancer Cell
, vol.2
, pp. 117-125
-
-
Shah, N.P.1
Nicoll, J.M.2
Nagar, B.3
-
34
-
-
0036682481
-
Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment
-
Roche-Lestienne C, Soenen-Cornu V, Grardel-Duflos N, et al. Several types of mutations of the Abl gene can be found in chronic myeloid leukemia patients resistant to STI571, and they can pre-exist to the onset of treatment. Blood 2002, 100:1014-1018.
-
(2002)
Blood
, vol.100
, pp. 1014-1018
-
-
Roche-Lestienne, C.1
Soenen-Cornu, V.2
Grardel-Duflos, N.3
-
35
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004, 350:2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
36
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 2004, 304:1497-1500.
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
37
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004, 101:13306-13311.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
38
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
Maheswaran S, Sequist LV, Nagrath S, et al. Detection of mutations in EGFR in circulating lung-cancer cells. N Engl J Med 2008, 359:366-377.
-
(2008)
N Engl J Med
, vol.359
, pp. 366-377
-
-
Maheswaran, S.1
Sequist, L.V.2
Nagrath, S.3
-
39
-
-
70349969478
-
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
-
Shah SP, Morin RD, Khattra J, et al. Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution. Nature 2009, 461:809-813.
-
(2009)
Nature
, vol.461
, pp. 809-813
-
-
Shah, S.P.1
Morin, R.D.2
Khattra, J.3
-
40
-
-
77956344675
-
Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma
-
Cooke SL, Ng CK, Melnyk N, et al. Genomic analysis of genetic heterogeneity and evolution in high-grade serous ovarian carcinoma. Oncogene 2010, 29:4905-4913.
-
(2010)
Oncogene
, vol.29
, pp. 4905-4913
-
-
Cooke, S.L.1
Ng, C.K.2
Melnyk, N.3
-
41
-
-
33646183071
-
Evolution of resistance during clonal expansion
-
Iwasa Y, Nowak MA, Michor F Evolution of resistance during clonal expansion. Genetics 2006, 172:2557-2566.
-
(2006)
Genetics
, vol.172
, pp. 2557-2566
-
-
Iwasa, Y.1
Nowak, M.A.2
Michor, F.3
-
42
-
-
78049398107
-
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
-
Yachida S, Jones S, Bozic I, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010, 467:1114-1117.
-
(2010)
Nature
, vol.467
, pp. 1114-1117
-
-
Yachida, S.1
Jones, S.2
Bozic, I.3
-
43
-
-
78049380554
-
The patterns and dynamics of genomic instability in metastatic pancreatic cancer
-
Campbell PJ, Yachida S, Mudie LJ, et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer. Nature 2010, 467:1109-1113.
-
(2010)
Nature
, vol.467
, pp. 1109-1113
-
-
Campbell, P.J.1
Yachida, S.2
Mudie, L.J.3
-
44
-
-
0037125582
-
Paclitaxel plus carboplatin versus standard chemotherapy with either single-agent carboplatin or cyclophosphamide, doxorubicin, and cisplatin in women with ovarian cancer: the ICON3 randomised trial
-
The International Collaborative Ovarian Neoplasm (ICON) Group
-
Paclitaxel plus carboplatin versus standard chemotherapy with either single-agent carboplatin or cyclophosphamide, doxorubicin, and cisplatin in women with ovarian cancer: the ICON3 randomised trial. Lancet 2002, 360:505-515. The International Collaborative Ovarian Neoplasm (ICON) Group.
-
(2002)
Lancet
, vol.360
, pp. 505-515
-
-
-
45
-
-
0025103224
-
Treatment of relapsed carcinoma of the ovary with cisplatin or carboplatin following initial treatment with these compounds
-
Gore ME, Fryatt I, Wiltshaw E, et al. Treatment of relapsed carcinoma of the ovary with cisplatin or carboplatin following initial treatment with these compounds. Gynecol Oncol 1990, 36:207-211.
-
(1990)
Gynecol Oncol
, vol.36
, pp. 207-211
-
-
Gore, M.E.1
Fryatt, I.2
Wiltshaw, E.3
-
46
-
-
78649467513
-
Does tumour dormancy offer a therapeutic target?
-
Goss PE, Chambers AF Does tumour dormancy offer a therapeutic target?. Nat Rev Cancer 2010, 10:871-877.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 871-877
-
-
Goss, P.E.1
Chambers, A.F.2
-
47
-
-
16844368698
-
Tumour stem cells and drug resistance
-
Dean M, Fojo T, Bates S Tumour stem cells and drug resistance. Nat Rev Cancer 2005, 5:275-284.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 275-284
-
-
Dean, M.1
Fojo, T.2
Bates, S.3
-
48
-
-
21744462100
-
Dynamics of chronic myeloid leukaemia
-
Michor F, Hughes TP, Iwasa Y, et al. Dynamics of chronic myeloid leukaemia. Nature 2005, 435:1267-1270.
-
(2005)
Nature
, vol.435
, pp. 1267-1270
-
-
Michor, F.1
Hughes, T.P.2
Iwasa, Y.3
-
49
-
-
78751661556
-
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells
-
Notta F, Mullighan CG, Wang JC, et al. Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. Nature 2011, 469:362-367.
-
(2011)
Nature
, vol.469
, pp. 362-367
-
-
Notta, F.1
Mullighan, C.G.2
Wang, J.C.3
-
50
-
-
78751644099
-
Genetic variegation of clonal architecture and propagating cells in leukaemia
-
Anderson K, Lutz C, van Delft FW, et al. Genetic variegation of clonal architecture and propagating cells in leukaemia. Nature 2011, 469:356-361.
-
(2011)
Nature
, vol.469
, pp. 356-361
-
-
Anderson, K.1
Lutz, C.2
van Delft, F.W.3
-
51
-
-
15744372810
-
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
-
Pao W, Wang TY, Riely GJ, et al. KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2005, 2:e17.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
-
52
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W, Miller VA, Politi KA, et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2005, 2:e73.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
-
53
-
-
63149190291
-
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas
-
Etemadmoghadam D, deFazio A, Beroukhim R, et al. Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas. Clin Cancer Res 2009, 15:1417-1427.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 1417-1427
-
-
Etemadmoghadam, D.1
deFazio, A.2
Beroukhim, R.3
-
54
-
-
4944229642
-
Hallmarks of 'BRCAness' in sporadic cancers
-
Turner N, Tutt A, Ashworth A Hallmarks of 'BRCAness' in sporadic cancers. Nat Rev Cancer 2004, 4:814-819.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 814-819
-
-
Turner, N.1
Tutt, A.2
Ashworth, A.3
-
55
-
-
0033575920
-
Deregulated cyclin E induces chromosome instability
-
Spruck CH, Won KA, Reed SI Deregulated cyclin E induces chromosome instability. Nature 1999, 401:297-300.
-
(1999)
Nature
, vol.401
, pp. 297-300
-
-
Spruck, C.H.1
Won, K.A.2
Reed, S.I.3
|