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Volumn 4, Issue 9, 2004, Pages 1399-1407

Attenuation of small-for-size liver graft injury by FTY720: Significance of cell survival Akt signaling pathway

Author keywords

Akt survival pathway; FTY720; Liver transplantation; Small for size graft

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 7; CASPASE 9; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FINGOLIMOD; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAD; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR;

EID: 4344581956     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2004.00527.x     Document Type: Article
Times cited : (40)

References (26)
  • 1
    • 0037444070 scopus 로고    scopus 로고
    • Distinct intragraft response pattern in relation to graft size in liver transplantation
    • Liang TB, Man K, Kin-Wah Lee T et al. Distinct intragraft response pattern in relation to graft size in liver transplantation. Transplantation 2003; 75: 673-678.
    • (2003) Transplantation , vol.75 , pp. 673-678
    • Liang, T.B.1    Man, K.2    Kin-Wah Lee, T.3
  • 2
    • 0035133227 scopus 로고    scopus 로고
    • Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1
    • Kim AH, Khursigara G, Sun X, Franke TF, Chao MV. Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 2001; 21: 893-901.
    • (2001) Mol Cell Biol , vol.21 , pp. 893-901
    • Kim, A.H.1    Khursigara, G.2    Sun, X.3    Franke, T.F.4    Chao, M.V.5
  • 3
    • 0034731449 scopus 로고    scopus 로고
    • Rapid activation of protein kinase B/Akt has a key role in antiapoptotic signaling during liver regeneration
    • Hong F, Nguyen VA, Shen X, Kunos G, Gao B. Rapid activation of protein kinase B/Akt has a key role in antiapoptotic signaling during liver regeneration. Biochem Biophys Res Commun 2000; 279: 974-979.
    • (2000) Biochem Biophys Res Commun , vol.279 , pp. 974-979
    • Hong, F.1    Nguyen, V.A.2    Shen, X.3    Kunos, G.4    Gao, B.5
  • 4
    • 0035902451 scopus 로고    scopus 로고
    • Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
    • Matsui T, Tao J, del Monte F et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation 2001; 104: 330-335.
    • (2001) Circulation , vol.104 , pp. 330-335
    • Matsui, T.1    Tao, J.2    Del Monte, F.3
  • 5
    • 0034651983 scopus 로고    scopus 로고
    • Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart
    • Fujio Y, Nguyen T, Wencker D, Kitsis RN, Walsh K. Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart. Circulation 2000; 101: 660-667.
    • (2000) Circulation , vol.101 , pp. 660-667
    • Fujio, Y.1    Nguyen, T.2    Wencker, D.3    Kitsis, R.N.4    Walsh, K.5
  • 6
    • 17144435270 scopus 로고    scopus 로고
    • Synthesis and immunosuppressive activity of 2-substituted 2-aminopropane-1,3-diols and 2-aminoethanols
    • Kiuchi M, Adachi K, Kohara T et al. Synthesis and immunosuppressive activity of 2-substituted 2-aminopropane-1,3-diols and 2-aminoethanols. J Med Chem 2000; 43: 2946-2961.
    • (2000) J Med Chem , vol.43 , pp. 2946-2961
    • Kiuchi, M.1    Adachi, K.2    Kohara, T.3
  • 7
    • 0038247846 scopus 로고    scopus 로고
    • FTY720 reduces T-cell recruitment into murine intestinal allograft and prevents activation of graft-infiltrating cells
    • Kimura T, Hasegawa T, Nakai H et al. FTY720 reduces T-cell recruitment into murine intestinal allograft and prevents activation of graft-infiltrating cells. Transplantation 2003; 75: 1469-1474.
    • (2003) Transplantation , vol.75 , pp. 1469-1474
    • Kimura, T.1    Hasegawa, T.2    Nakai, H.3
  • 8
    • 0033592304 scopus 로고    scopus 로고
    • FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation
    • Hwang MW, Matsumori A, Furukawa Y et al. FTY720, a new immunosuppressant, promotes long-term graft survival and inhibits the progression of graft coronary artery disease in a murine model of cardiac transplantation. Circulation 1999; 100: 1322-1329.
    • (1999) Circulation , vol.100 , pp. 1322-1329
    • Hwang, M.W.1    Matsumori, A.2    Furukawa, Y.3
  • 9
    • 0035671314 scopus 로고    scopus 로고
    • FTY720, a novel transplantation drug, modulates lymphocyte migratory responses to chemokines
    • Chen S, Bacon KB, Garcia G et al. FTY720, a novel transplantation drug, modulates lymphocyte migratory responses to chemokines. Transplant Proc 2001; 33: 3057-3063.
    • (2001) Transplant Proc , vol.33 , pp. 3057-3063
    • Chen, S.1    Bacon, K.B.2    Garcia, G.3
  • 10
    • 0037077308 scopus 로고    scopus 로고
    • The immune modulator FTY720 targets sphingosine 1-phosphate receptors
    • Brinkmann V, Davis MD, Heise CE et al. The immune modulator FTY720 targets sphingosine 1-phosphate receptors. J Biol Chem 2002; 277: 21453-21457.
    • (2002) J Biol Chem , vol.277 , pp. 21453-21457
    • Brinkmann, V.1    Davis, M.D.2    Heise, C.E.3
  • 11
    • 1642580757 scopus 로고    scopus 로고
    • Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
    • Matloubian M, Lo CG, Cinamon G et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature 2004; 427: 355-360.
    • (2004) Nature , vol.427 , pp. 355-360
    • Matloubian, M.1    Lo, C.G.2    Cinamon, G.3
  • 12
    • 0036820441 scopus 로고    scopus 로고
    • FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration
    • Anselmo DM, Amersi FF, Shen XD et al. FTY720 pretreatment reduces warm hepatic ischemia reperfusion injury through inhibition of T-lymphocyte infiltration. Am J Transplant 2002; 2: 843-849.
    • (2002) Am J Transplant , vol.2 , pp. 843-849
    • Anselmo, D.M.1    Amersi, F.F.2    Shen, X.D.3
  • 13
    • 0035077051 scopus 로고    scopus 로고
    • FTY 720 prevents ischemic reperfusion damage in rat kidneys
    • Troncoso P, Ortiz M, Martinez L, Kahan BD. FTY 720 prevents ischemic reperfusion damage in rat kidneys. Transplant Proc 2001; 33:857-859.
    • (2001) Transplant Proc , vol.33 , pp. 857-859
    • Troncoso, P.1    Ortiz, M.2    Martinez, L.3    Kahan, B.D.4
  • 14
    • 0035097777 scopus 로고    scopus 로고
    • Liver transplantation in rats using small-for-size grafts: A study of hemodynamic and morphological changes
    • Man K, Lo CM, Ng IO et al. Liver transplantation in rats using small-for-size grafts: a study of hemodynamic and morphological changes. Arch Surg 2001; 136: 280-285.
    • (2001) Arch Surg , vol.136 , pp. 280-285
    • Man, K.1    Lo, C.M.2    Ng, I.O.3
  • 15
    • 0037316049 scopus 로고    scopus 로고
    • Graft injury in relation to graft size in right lobe live donor liver transplantation: A study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression
    • Man K, Fan ST, Lo CM et al. Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and intragraft gene expression. Ann Surg 2003; 237: 256-264.
    • (2003) Ann Surg , vol.237 , pp. 256-264
    • Man, K.1    Fan, S.T.2    Lo, C.M.3
  • 16
    • 0037387674 scopus 로고    scopus 로고
    • Intragraft gene expression profiles by cDNA microarray in small-for-size liver grafts
    • Man K, Lo CM, Lee TK, Li XL, Ng IO, Fan ST. Intragraft gene expression profiles by cDNA microarray in small-for-size liver grafts. Liver Transpl 2003; 9: 425-432.
    • (2003) Liver Transpl , vol.9 , pp. 425-432
    • Man, K.1    Lo, C.M.2    Lee, T.K.3    Li, X.L.4    Ng, I.O.5    Fan, S.T.6
  • 17
    • 0038511371 scopus 로고    scopus 로고
    • Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation
    • Lo CM, Liu CL, Fan ST. Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation. Liver Transpl 2003; 9: 626-628.
    • (2003) Liver Transpl , vol.9 , pp. 626-628
    • Lo, C.M.1    Liu, C.L.2    Fan, S.T.3
  • 18
    • 3042660567 scopus 로고    scopus 로고
    • FK409 ameliorates small-for-size graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway
    • in press
    • Man K, Lee TK, Liang TB et al. FK409 ameliorates small-for-size graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway. Ann Surg, 2004, in press.
    • (2004) Ann Surg
    • Man, K.1    Lee, T.K.2    Liang, T.B.3
  • 19
    • 0033857388 scopus 로고    scopus 로고
    • Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo
    • Luo Z, Fujio Y, Kureishi Y et al. Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo. J Clin Invest 2000; 106: 493-499.
    • (2000) J Clin Invest , vol.106 , pp. 493-499
    • Luo, Z.1    Fujio, Y.2    Kureishi, Y.3
  • 20
    • 0037013179 scopus 로고    scopus 로고
    • Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion
    • Scotland RS, Morales-Ruiz M, Chen Y et al. Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circ Res 2002; 90: 904-910.
    • (2002) Circ Res , vol.90 , pp. 904-910
    • Scotland, R.S.1    Morales-Ruiz, M.2    Chen, Y.3
  • 21
    • 0032720683 scopus 로고    scopus 로고
    • Lessons from genetically engineered animal models. IV. Nitric oxide synthase gene knockout mice
    • Mashimo H, Goyal RK. Lessons from genetically engineered animal models. IV. Nitric oxide synthase gene knockout mice. Am J Physiol 1999; 277: G745-G750.
    • (1999) Am J Physiol , vol.277
    • Mashimo, H.1    Goyal, R.K.2
  • 22
    • 0034889062 scopus 로고    scopus 로고
    • Endothelial exposure to hypoxia induces Egr-1 expression involving PKCalpha-mediated Ras/Raf-1/ERK1/2 pathway
    • Lo LW, Cheng JJ, Chiu JJ, Wung BS, Liu YC, Wang DL. Endothelial exposure to hypoxia induces Egr-1 expression involving PKCalpha-mediated Ras/Raf-1/ERK1/2 pathway. J Cell Physiol 2001; 188: 304-312.
    • (2001) J Cell Physiol , vol.188 , pp. 304-312
    • Lo, L.W.1    Cheng, J.J.2    Chiu, J.J.3    Wung, B.S.4    Liu, Y.C.5    Wang, D.L.6
  • 23
    • 0037784056 scopus 로고    scopus 로고
    • Hyperoxia induces Egr-1 expression through activation of extracellular signal-regulated kinase 1/2 pathway
    • Jones N, Agani FH. Hyperoxia induces Egr-1 expression through activation of extracellular signal-regulated kinase 1/2 pathway. J Cell Physiol 2003; 196: 326-333.
    • (2003) J Cell Physiol , vol.196 , pp. 326-333
    • Jones, N.1    Agani, F.H.2
  • 24
    • 0035110655 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice
    • Sass G, Koerber K, Bang R, Guehring H, Tiegs G. Inducible nitric oxide synthase is critical for immune-mediated liver injury in mice. J Clin Invest 2001; 107: 439-447.
    • (2001) J Clin Invest , vol.107 , pp. 439-447
    • Sass, G.1    Koerber, K.2    Bang, R.3    Guehring, H.4    Tiegs, G.5
  • 25
    • 0038689038 scopus 로고    scopus 로고
    • Effect of mesocaval shunt on survival of small-for-size liver grafts: Experimental study in pigs
    • Smyrniotis VE, Kostopanagiotou G, Theodoraki K et al. Effect of mesocaval shunt on survival of small-for-size liver grafts: experimental study in pigs. Transplantation 2003; 75: 1737-1740.
    • (2003) Transplantation , vol.75 , pp. 1737-1740
    • Smyrniotis, V.E.1    Kostopanagiotou, G.2    Theodoraki, K.3
  • 26
    • 1842775489 scopus 로고    scopus 로고
    • Persistence of impaired hepatic microcirculation after nonarterialized liver transplantation in the rat
    • Tawadrous MN, Zimmermann A, Zhang XY, Wheatley AM. Persistence of impaired hepatic microcirculation after nonarterialized liver transplantation in the rat. Microcirculation 2002; 9: 363-375.
    • (2002) Microcirculation , vol.9 , pp. 363-375
    • Tawadrous, M.N.1    Zimmermann, A.2    Zhang, X.Y.3    Wheatley, A.M.4


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