FTY720 prevents ischemia/reperfusion injury-associated arrhythmias in an ex vivo rat heart model via activation of Pak1/Akt signaling

Journal of Molecular and Cellular Cardiology

Volumn 48, Issue 2, 2010, Pages 406-414

  Egom, E Eroume A ^a   Ke, Yunbo ^b   Musa, Hanny ^a   Mohamed, Tamer M A ^a   Wang, Tao ^a   Cartwright, Elizabeth ^a   Solaro, R John ^b   Lei, Ming ^a  

^a Maternal and Fetal Health Research Centre   (United Kingdom)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

Akt; FTY720; Pak1; S1P

Indexed keywords

FINGOLIMOD; P21 ACTIVATED KINASE 1; PROTEIN KINASE B; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR CONDUCTION; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME ACTIVATION; EX VIVO STUDY; HEART ARRHYTHMIA; HEART ATRIUM; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART STRESS; HEART VENTRICLE; HEART VENTRICLE EXTRASYSTOLE; HEART VENTRICLE TACHYCARDIA; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; SINUS BRADYCARDIA; SINUS NODE; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; ARRHYTHMIAS, CARDIAC; DISEASE MODELS, ANIMAL; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; INTRACELLULAR SPACE; MALE; P21-ACTIVATED KINASES; PERTUSSIS TOXIN; PHOSPHORYLATION; PROPYLENE GLYCOLS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, WISTAR; RECEPTORS, LYSOSPHINGOLIPID; REPERFUSION INJURY; RNA, MESSENGER; SIGNAL TRANSDUCTION; SINOATRIAL NODE; SPHINGOSINE; TIME FACTORS;

RATTUS;

EID: 74149086892     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2009.10.009     Document Type: Article

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