CRIP1a switches cannabinoid receptor agonist/antagonist-mediated protection from glutamate excitotoxicity

Neuroscience Letters

Volumn 503, Issue 3, 2011, Pages 224-228

  Stauffer, Brandon ^a   Wallis, Kathleen T ^a   Wilson, Steven P ^b   Egertová, Michaela ^c   Elphick, Maurice R ^c   Lewis, Deborah L ^a   Hardy, Lori Redmond ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF SOUTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

CB 1 cannabinoid receptor; Cell death; CRIP1a; Glutamate toxicity; Neuroprotection

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; CANNABINOID 1 RECEPTOR; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; GLUTAMIC ACID; NEUROPROTECTIVE AGENT; PROTEIN CRIP1A; RIMONABANT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL COUNT; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; EXCITOTOXICITY; IN VITRO STUDY; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BENZOXAZINES; BLOTTING, WESTERN; CARRIER PROTEINS; CELL COUNT; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; EXCITATORY AMINO ACIDS; GENETIC VECTORS; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; LENTIVIRUS; MORPHOLINES; NAPHTHALENES; NEUROPROTECTIVE AGENTS; PIPERIDINES; PLASMIDS; PYRAZOLES; RATS; RATS, LONG-EVANS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, CANNABINOID, CB1; RECEPTORS, CANNABINOID; SYNAPSINS;

EID: 80053227258     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2011.08.041     Document Type: Article

References (33)

1. 1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity. Neurosci. Lett. 2001, 309:197-201.
2. Berger C., Schmid P.C., Schabitz W.-R., Wolf M., Schwab S., Schmid H.H.O. Massive accumulation of N-acylethanolamines after stroke. Cell signaling in acute cerebral ischemia?. J. Neurochem. 2004, 88:1159-1167.
3. Berrendero F., García-Gil L., Hernández M.L., Romero J., Cebeira M., de Miguel R., Ramos J.A., Fernández-Ruiz J.J. Localization of mRNA expression and activation of signal transduction mechanisms for cannabinoid receptor in rat brain during fetal development. Development 1998, 125:3179-3188.
4. Blázquez C., Chiarlone A., Sagredo O., Aguado T., Pazos M.R., Resel E., Palazuelos J., Julien B., Salazar M., Börner C., Benito C., Carrasco C., Diez-Zaera M., Paoletti P., Díaz-Hernández M., Ruiz C., Sendtner M., Lucas J.J., de Yébenes J.G., Marsicano G., Monory K., Lutz B., Romero J., Alberch J., Ginés S., Kraus J., Fernández-Ruiz J., Galve-Roperh I., Guzmán M. Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease. Brain 2001, 143:119-136.
5. de Almeida L.P., Zala D., Aebischer P., Deglon N. Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease. Neurobiol. Dis. 2001, 8:433-446.
6. de Almeida L.P., Ross C.A., Zala D., Aebischer P., Deglon N. Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length. J. Neurosci. 2002, 22:3473-3483.
7. Déglon N., Tseng J.L., Bensadoun J.C., Zurn A.D., Arsenijevic Y., Pereira D.A., Zufferey R., Trono D., Aebischer P. Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease. Hum. Gene Ther. 2000, 11:179-190.
8. Donello J.E., Loeb J.E., Hope T.J. Woodchuck hepatitis virus contains a tripartite posttranscriptional regulatory element. J. Virol. 1998, 72:5085-5092.
9. 1 receptor. NeuroReport 2001, 12:3973-3978.
10. 1. J. Comp. Neurol. 2000, 422:159-171.
11. 1 receptors with L1 and GAP-43 in forebrain white matter regions during fetal rat brain development: evidence for a role of these receptors in axonal growth and guidance. Neuroscience 2008, 153:687-699.
12. Guggenhuber S., Monory K., Lutz B., Klugmann M. AAV vector-mediated overexpression of CB1 cannabinoid receptor in pyramidal neurons of the hippocampus protects against seizure-induced excitotoxicity. PloS One 2010, 5:e15707.
13. Hampson A.J., Grimaldi M. Cannabinoid receptor activation and elevated cyclic AMP reduce glutamate toxicity. Eur. J. Neurosci. 2001, 13:1529-1536.
14. 1 receptor function protects against in vivo disseminating brain damage following NMDA-induced excitotoxicity. J. Neurochem. 2002, 82:154-158.
15. Herkenham M., Lynn A.B., Little M.D., Johnson M.R., Melvin L.S., de Costa B.R., Rice K.C. Cannabinoid receptor localization in brain. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:1932-1936.
16. Howlett A.C., Barth F., Bonner T.I., Cabral G., Casellas P., Devane W.A., Felder C.C., Herkenham M., Mackie K., Martin B.R., Mechoulam R., Pertwee R.G. International union of pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol. Rev. 2002, 54:161-202.
17. Khaspekov L.G., Brenz Verca M.S., Frumkina L.E., Hermann H., Marsicano G., Lutz B. Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity. Eur. J. Neurosci. 2004, 19:1691-1698.
18. Kugler S., Kilic E., Bahr M. Human synapsin-1 gene promoter confers highly neuron-specific long-term transgene expression from an adenoviral vector in the adult rat brain depending on the transduced area. Gene. Ther. 2003, 10:337-347.
19. Ledent C., Valverde O., Cossu G., Petitet F., Aubert J.F., Beslot F., Bohme G.A., Imperato A., Pedrazzini T., Roques B.P., Vassart G., Fratta W., Parmentier M. Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science 1999, 283:401-404.
20. 1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus. J. Neurosci. 2008, 28:2976-2990.
21. Marsicano G., Wotjak C.T., Azad S.C., Bisogno T., Rammes G., Cascio M.G., Hermann H., Tang J., Hofmann C., Zieglgansberger W., Di Marzo V., Lutz B. The endogenous cannabinoid system controls extinction of aversive memories. Nature 2002, 418:530-534.
22. Marsicano G., Goodenough S., Monory K., Hermann H., Eder M., Cannich A., Azad S.C., Cascio M.G., Gutierrez S.O., van der Stelt M., Lopez-Rodriguez M.L., Casanova E., Schutz G., Zieglgansberger W., Di Marzo V., Behl C., Lutz B. CB1 cannabinoid receptors and on-demand defense against excitotoxicity. Science 2003, 302:84-88.
23. 1 cannabinoid receptor blockade is protective during transient, focal cerebral ischemia. Neuroscience 2004, 129:743-750.
24. Nagayama T., Sinor A.D., Simon R.P., Chen J., Graham S.H., Jin K., Greenberg D.A. Cannabinoids and neuroprotection in global and focal cerebral ischemia and in neuronal cultures. J. Neurosci. 1999, 19:2987-2995.
25. 1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a. Mol. Pharm. 2007, 72:1557-1566.
26. Parmentier-Batteur S., Jin K., Mao X.O., Xie L., Greenberg D.A. Increased severity of stroke in CB1 cannabinoid receptor knock-out mice. J. Neurosci. 2002, 222:9771-9775.
27. L gene expression. J. Neurosci. Res. 2006, 83:1058-1065.
28. Redmond L., Kashani A.H., Ghosh A. Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription. Neuron 2002, 34:999-1010.
29. Shen M., Thayer S.A. Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. Mol. Pharmacol. 1998, 54:459-462.
30. 1 cannabinoid receptor. J. Mol. Endocrinol. 2010, 44:75-85.
31. Wang Q., Peng Y., Chen S., Gou X., Ho B., Du J., Lu Y., Xiong L. Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid system. Stroke 2009, 40:2157-2164.
32. 2 receptor activation during cerebral ischemic/reperfusion injury. Neuroscience 2008, 152:753-760.
33. Zhuang S.Y., Bridges D., Grigorenko E., McCloud S., Boon A., Hampson R.E., Deadwyler S.A. Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores. Neuropharmacology 2005, 48:1086-1096.