The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier

Molecular Pharmacology

Volumn 80, Issue 4, 2011, Pages 621-629

  Halwachs, Sandra ^a   Lakoma, Cathleen ^a   Schäfer, Ingo ^a   Seibel, Peter ^a   Honscha, Walther ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CARBAMAZEPINE; FOLIC ACID; GABAPENTIN; MESSENGER RNA; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 3; MULTIDRUG RESISTANCE PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; ORGANIC ANION TRANSPORTER 3; PHENOBARBITAL; REDUCED FOLATE CARRIER;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD CEREBROSPINAL FLUID BARRIER; CELLULAR DISTRIBUTION; CHOROID PLEXUS; CONFOCAL MICROSCOPY; DOWN REGULATION; DRUG UPTAKE; GENE EXPRESSION; IN VITRO STUDY; LIVER; NEUROTOXICITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTICONVULSANTS; BIOLOGICAL TRANSPORT; CARBAMAZEPINE; CELL LINE, TRANSFORMED; CHOROID PLEXUS; DOWN-REGULATION; MALE; METHOTREXATE; PHENOBARBITAL; RATS; RATS, SPRAGUE-DAWLEY; REDUCED FOLATE CARRIER PROTEIN;

EID: 80053195753     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.072421     Document Type: Article

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