Vectorial ligand transport through mammalian choroid plexus

Pharmaceutical Research

Volumn 27, Issue 10, 2010, Pages 2054-2062

  Spector, Reynold ^a   Johanson, Conrad E ^b  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b Brown University Program in Neurosurgery   (United States)

Author keywords

brain nourishment; cerebrospinal fluid; multidrug resistance proteins; neuroprotection; organic acid transporting polypeptides

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; CARRIER PROTEIN; CONCENTRATIVE NUCLEOSIDE TRANSPORTER 3; DIGOXIN; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; FOLATE RECEPTOR; FOLATE RECEPTOR ALPHA; LEUKOTRIENE C4; LIGAND; MEMBRANE PROTEIN; METHOTREXATE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 4; NUCLEOSIDE; ORGANIC ACID TRANSPORTING POLYPEPTIDE 2; ORGANIC ACID TRANSPORTING POLYPEPTIDE 3; ORGANIC ACID TRANSPORTING POLYPEPTIDE D; PROSTAGLANDIN; PROSTAGLANDIN TRANSPORT PROTEIN; PROTON COUPLED FOLATE TRANSPORTER; REDUCED FOLATE CARRIER; THIAMINE PHOSPHATE; UNCLASSIFIED DRUG;

BLOOD BRAIN BARRIER; CEREBROSPINAL FLUID; CHOROID PLEXUS; DRUG UPTAKE; HUMAN; KNOCKOUT GENE; LIGAND BINDING; MEMBRANE TRANSPORT; MOLECULAR DYNAMICS; NEUROCHEMISTRY; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN POLYMORPHISM; REVIEW; SIGNAL TRANSDUCTION; TRANSPORT KINETICS;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CHOROID PLEXUS; HUMANS; LIGANDS; MEMBRANE TRANSPORT PROTEINS; PHARMACEUTICAL PREPARATIONS; SUBSTRATE SPECIFICITY;

EID: 77957328846     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-010-0162-2     Document Type: Review

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