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Volumn 8, Issue , 2011, Pages

The "Alzheimer's disease signature": Potential perspectives for novel biomarkers

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ALPHA 1 ANTICHYMOTRYPSIN; ALPHA 2 MACROGLOBULIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E2; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; BETA SECRETASE 1; BRAIN DERIVED NEUROTROPHIC FACTOR; CHROMOGRANIN A; CLATHRIN ASSEMBLY PROTEIN; CLUSTERIN; COMPLEMENT FACTOR H; CYCLIN DEPENDENT KINASE 5; EPHRIN RECEPTOR A1; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUROMODULIN; PITTSBURGH COMPOUND B; PRESENILIN 1; PRESENILIN 2; SORTILIN; TAU PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNINDEXED DRUG; VASCULOTROPIN; VISININ;

EID: 80053172278     PISSN: None     EISSN: 17424933     Source Type: Journal    
DOI: 10.1186/1742-4933-8-7     Document Type: Review
Times cited : (17)

References (94)
  • 1
    • 77949336151 scopus 로고    scopus 로고
    • 2010 Alzheimer's disease facts and figures
    • Alzheimer's Association
    • Alzheimer's Association 2010 Alzheimer's disease facts and figures. Alzheimers Dement 2010, 6:158-94. Alzheimer's Association.
    • (2010) Alzheimers Dement , vol.6 , pp. 158-194
  • 2
    • 72149110396 scopus 로고    scopus 로고
    • Alzheimer's disease biomarker discovery in symptomatic and asymptomatic patients: experimental approaches and future clinical applications
    • 10.1016/j.exger.2009.09.007, 2840994, 19796674
    • Ho L, Fivecoat H, Wang J, Pasinetti GM. Alzheimer's disease biomarker discovery in symptomatic and asymptomatic patients: experimental approaches and future clinical applications. Exp Gerontol 2010, 45:15-22. 10.1016/j.exger.2009.09.007, 2840994, 19796674.
    • (2010) Exp Gerontol , vol.45 , pp. 15-22
    • Ho, L.1    Fivecoat, H.2    Wang, J.3    Pasinetti, G.M.4
  • 3
    • 0037045836 scopus 로고    scopus 로고
    • Uses and abuses of screening tests
    • 10.1016/S0140-6736(02)07948-5, 11897304
    • Grimes DA, Schulz KF. Uses and abuses of screening tests. Lancet 2002, 359:881-4. 10.1016/S0140-6736(02)07948-5, 11897304.
    • (2002) Lancet , vol.359 , pp. 881-884
    • Grimes, D.A.1    Schulz, K.F.2
  • 4
    • 75449102536 scopus 로고    scopus 로고
    • Alzheimer's disease
    • 10.1056/NEJMra0909142, 20107219
    • Querfurth HW, LaFerla FM. Alzheimer's disease. N Engl J Med 2010, 362:329-44. 10.1056/NEJMra0909142, 20107219.
    • (2010) N Engl J Med , vol.362 , pp. 329-344
    • Querfurth, H.W.1    LaFerla, F.M.2
  • 6
    • 0026597063 scopus 로고
    • Alzheimer's disease: the amyloid cascade hypothesis
    • 10.1126/science.1566067, 1566067
    • Hardy JA, Higgins GA. Alzheimer's disease: the amyloid cascade hypothesis. Science 1992, 256:184-185. 10.1126/science.1566067, 1566067.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 7
    • 33746310315 scopus 로고    scopus 로고
    • Alzheimer's disease
    • 10.1016/S0140-6736(06)69113-7, 16876668
    • Blennow K, de Leon MJ, Zetterberg H. Alzheimer's disease. Lancet 2006, 368:387-403. 10.1016/S0140-6736(06)69113-7, 16876668.
    • (2006) Lancet , vol.368 , pp. 387-403
    • Blennow, K.1    de Leon, M.J.2    Zetterberg, H.3
  • 8
    • 49449108546 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease
    • 10.1001/archneur.65.8.1102, 18695061
    • Zetterberg H, Andreasson U, Hansson O, Wu G, Sankaranarayanan S, Andersson ME, et al. Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease. Arch Neurol 2008, 65:1102-1107. 10.1001/archneur.65.8.1102, 18695061.
    • (2008) Arch Neurol , vol.65 , pp. 1102-1107
    • Zetterberg, H.1    Andreasson, U.2    Hansson, O.3    Wu, G.4    Sankaranarayanan, S.5    Andersson, M.E.6
  • 9
    • 34249942064 scopus 로고    scopus 로고
    • Levels of β-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment
    • 10.1001/archpsyc.64.6.718, 17548753
    • Zhong Z, Ewers M, Teipel S, Bürger K, Wallin A, Blennow K, et al. Levels of β-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment. Arch Gen Psychiatry 2007, 64:718-726. 10.1001/archpsyc.64.6.718, 17548753.
    • (2007) Arch Gen Psychiatry , vol.64 , pp. 718-726
    • Zhong, Z.1    Ewers, M.2    Teipel, S.3    Bürger, K.4    Wallin, A.5    Blennow, K.6
  • 10
    • 77956470750 scopus 로고    scopus 로고
    • Alzheimer disease
    • 10.1016/j.disamonth.2010.06.001, 2941917, 20831921
    • Castellani RJ, Rolston RK, Smith MA. Alzheimer disease. Dis Mon 2010, 56:484-546. 10.1016/j.disamonth.2010.06.001, 2941917, 20831921.
    • (2010) Dis Mon , vol.56 , pp. 484-546
    • Castellani, R.J.1    Rolston, R.K.2    Smith, M.A.3
  • 11
    • 60349125886 scopus 로고    scopus 로고
    • Reassessing the amyloid cascade hypothesis of Alzheimer's disease
    • 10.1016/j.biocel.2008.12.015, 2680505, 19124085
    • Pimplikar SW. Reassessing the amyloid cascade hypothesis of Alzheimer's disease. Int J Biochem Cell Biol 2009, 41:1261-68. 10.1016/j.biocel.2008.12.015, 2680505, 19124085.
    • (2009) Int J Biochem Cell Biol , vol.41 , pp. 1261-1268
    • Pimplikar, S.W.1
  • 12
    • 71849099881 scopus 로고    scopus 로고
    • Amyloid beta and APP as biomarkers for Alzheimer's disease
    • 10.1016/j.exger.2009.08.002, 19698775
    • Zetterberg H, Blennow K, Hanse E. Amyloid beta and APP as biomarkers for Alzheimer's disease. Exp Gerontol 2010, 45:23-9. 10.1016/j.exger.2009.08.002, 19698775.
    • (2010) Exp Gerontol , vol.45 , pp. 23-29
    • Zetterberg, H.1    Blennow, K.2    Hanse, E.3
  • 13
    • 3543095180 scopus 로고    scopus 로고
    • Identification of post-mortem cerebrospinal fluid proteins as potential biomarkers of ischemia and neurodegeneration
    • 10.1002/pmic.200300822, 15274117
    • Lescuyer P, Allard L, Zimmermann-Ivol CG, Burgess JA, Hughes-Frutiger S, Burkhard PR, et al. Identification of post-mortem cerebrospinal fluid proteins as potential biomarkers of ischemia and neurodegeneration. Proteomics 2004, 4:2234-2241. 10.1002/pmic.200300822, 15274117.
    • (2004) Proteomics , vol.4 , pp. 2234-2241
    • Lescuyer, P.1    Allard, L.2    Zimmermann-Ivol, C.G.3    Burgess, J.A.4    Hughes-Frutiger, S.5    Burkhard, P.R.6
  • 14
    • 33749120499 scopus 로고    scopus 로고
    • Proteomic analysis of cerebrospinal fluid changes related to postmortem interval
    • 10.1373/clinchem.2006.070508, 16887899
    • Finehout EJ, Franck Z, Relkin N, Lee KH. Proteomic analysis of cerebrospinal fluid changes related to postmortem interval. Clin Chem 2006, 52:1906-1913. 10.1373/clinchem.2006.070508, 16887899.
    • (2006) Clin Chem , vol.52 , pp. 1906-1913
    • Finehout, E.J.1    Franck, Z.2    Relkin, N.3    Lee, K.H.4
  • 15
    • 34548301393 scopus 로고    scopus 로고
    • Tauopathies
    • 10.1007/s00018-007-7220-x, 17604998
    • Hernandez F, Avila J. Tauopathies. Cell Mol Life Sci 2007, 64:2219-2233. 10.1007/s00018-007-7220-x, 17604998.
    • (2007) Cell Mol Life Sci , vol.64 , pp. 2219-2233
    • Hernandez, F.1    Avila, J.2
  • 16
    • 34548191034 scopus 로고    scopus 로고
    • Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis
    • 10.1074/jbc.M703269200, 17562708
    • Hanger DP, Byers HL, Wray S, Leung KY, Saxton MJ, Seereeram A, et al. Novel phosphorylation sites in tau from Alzheimer brain support a role for casein kinase 1 in disease pathogenesis. J Biol Chem 2007, 282:23645-23654. 10.1074/jbc.M703269200, 17562708.
    • (2007) J Biol Chem , vol.282 , pp. 23645-23654
    • Hanger, D.P.1    Byers, H.L.2    Wray, S.3    Leung, K.Y.4    Saxton, M.J.5    Seereeram, A.6
  • 18
    • 56349119351 scopus 로고    scopus 로고
    • Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis
    • 10.1016/j.neuron.2008.11.007, 2692134, 19038212
    • Small SA, Duff K. Linking Abeta and tau in late-onset Alzheimer's disease: a dual pathway hypothesis. Neuron 2008, 60:534-42. 10.1016/j.neuron.2008.11.007, 2692134, 19038212.
    • (2008) Neuron , vol.60 , pp. 534-542
    • Small, S.A.1    Duff, K.2
  • 19
    • 68949150683 scopus 로고    scopus 로고
    • Amyloid-beta, tau, and dementia
    • Takashima A. Amyloid-beta, tau, and dementia. J Alzheimers Dis 2009, 17:729-36.
    • (2009) J Alzheimers Dis , vol.17 , pp. 729-736
    • Takashima, A.1
  • 20
    • 67651180986 scopus 로고    scopus 로고
    • The amyloid hypothesis for Alzheimer's disease: a critical reappraisal
    • 10.1111/j.1471-4159.2009.06181.x, 19457065
    • Hardy J. The amyloid hypothesis for Alzheimer's disease: a critical reappraisal. J Neurochem 2009, 110:1129-1134. 10.1111/j.1471-4159.2009.06181.x, 19457065.
    • (2009) J Neurochem , vol.110 , pp. 1129-1134
    • Hardy, J.1
  • 21
    • 71949090833 scopus 로고    scopus 로고
    • Mitochondrial trafficking of APP and alpha synuclein: relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases
    • 2790550, 19619643
    • Devi L, Anandatheerthavarada HK. Mitochondrial trafficking of APP and alpha synuclein: relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases. Biochim Biophys Acta 2010, 1802:11-19. 2790550, 19619643.
    • (2010) Biochim Biophys Acta , vol.1802 , pp. 11-19
    • Devi, L.1    Anandatheerthavarada, H.K.2
  • 22
    • 34248187134 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders
    • 10.2741/2130, 17127365
    • Mancuso C, Scapagnini G, Currò D, Giuffrida Stella AM, De Marco C, Butterfield DA, Calabrese V. Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders. Front Biosci 2007, 12:1107-1123. 10.2741/2130, 17127365.
    • (2007) Front Biosci , vol.12 , pp. 1107-1123
    • Mancuso, C.1    Scapagnini, G.2    Currò, D.3    Giuffrida Stella, A.M.4    De Marco, C.5    Butterfield, D.A.6    Calabrese, V.7
  • 24
    • 78651061790 scopus 로고    scopus 로고
    • The role of DYRK1A in neurodegenerative diseases
    • 10.1111/j.1742-4658.2010.07955.x, 21156028
    • Wegiel J, Gong CX, Hwang YW. The role of DYRK1A in neurodegenerative diseases. FEBS J 2011, 278:236-45. 10.1111/j.1742-4658.2010.07955.x, 21156028.
    • (2011) FEBS J , vol.278 , pp. 236-245
    • Wegiel, J.1    Gong, C.X.2    Hwang, Y.W.3
  • 25
    • 33846533244 scopus 로고    scopus 로고
    • The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease
    • Kimura R, Kamino K, Yamamoto M, Nuripa A, Kida T, Kazui H, et al. The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease. Hum Mol Genet 2007, 16:15-23.
    • (2007) Hum Mol Genet , vol.16 , pp. 15-23
    • Kimura, R.1    Kamino, K.2    Yamamoto, M.3    Nuripa, A.4    Kida, T.5    Kazui, H.6
  • 26
    • 0029065685 scopus 로고
    • Apolipoprotein E and Alzheimer disease
    • 10.1073/pnas.92.11.4725, 41779, 7761390
    • Strittmatter WJ, Roses AD. Apolipoprotein E and Alzheimer disease. Proc Natl Acad Sci USA 1995, 92:4725-4727. 10.1073/pnas.92.11.4725, 41779, 7761390.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4725-4727
    • Strittmatter, W.J.1    Roses, A.D.2
  • 27
    • 0027194791 scopus 로고
    • Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
    • 10.1126/science.8346443, 8346443
    • Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 1993, 261:921-923. 10.1126/science.8346443, 8346443.
    • (1993) Science , vol.261 , pp. 921-923
    • Corder, E.H.1    Saunders, A.M.2    Strittmatter, W.J.3    Schmechel, D.E.4    Gaskell, P.C.5    Small, G.W.6
  • 28
    • 77953431148 scopus 로고    scopus 로고
    • Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer disease
    • 10.1073/pnas.1001412107, 2890481, 20479234, Alzheimer's Disease Neuroimaging Initiative
    • Wolk DA, Dickerson BC, . Alzheimer's Disease Neuroimaging Initiative Apolipoprotein E (APOE) genotype has dissociable effects on memory and attentional-executive network function in Alzheimer disease. Proc Natl Acad Sci USA 2010, 107:10256-10261. 10.1073/pnas.1001412107, 2890481, 20479234, Alzheimer's Disease Neuroimaging Initiative.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 10256-10261
    • Wolk, D.A.1    Dickerson, B.C.2
  • 29
    • 70349558522 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
    • 10.1038/ng.440, 2845877, 19734902
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, Hamshere ML, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nature Genet 2009, 41:1088-93. 10.1038/ng.440, 2845877, 19734902.
    • (2009) Nature Genet , vol.41 , pp. 1088-1093
    • Harold, D.1    Abraham, R.2    Hollingworth, P.3    Sims, R.4    Gerrish, A.5    Hamshere, M.L.6
  • 30
    • 0036678856 scopus 로고    scopus 로고
    • Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease
    • 10.1073/pnas.162228299, 125060, 12145324
    • DeMattos RB, O'dell MA, Parsadanian M, Taylor JW, Harmony JA, Bales KR, et al. Clusterin promotes amyloid plaque formation and is critical for neuritic toxicity in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 2002, 99:10843-10848. 10.1073/pnas.162228299, 125060, 12145324.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 10843-10848
    • DeMattos, R.B.1    O'dell, M.A.2    Parsadanian, M.3    Taylor, J.W.4    Harmony, J.A.5    Bales, K.R.6
  • 31
    • 9144224765 scopus 로고    scopus 로고
    • ApoE and clusterin cooperatively suppress Abeta levels and deposition: Evidence that ApoE regulates extracellular Abeta metabolism in vivo
    • 10.1016/S0896-6273(03)00850-X, 14741101
    • DeMattos RB, Cirrito JR, Parsadanian M, May PC, O'Dell MA, Taylor JW. ApoE and clusterin cooperatively suppress Abeta levels and deposition: Evidence that ApoE regulates extracellular Abeta metabolism in vivo. Neuron 2004, 41:193-202. 10.1016/S0896-6273(03)00850-X, 14741101.
    • (2004) Neuron , vol.41 , pp. 193-202
    • DeMattos, R.B.1    Cirrito, J.R.2    Parsadanian, M.3    May, P.C.4    O'Dell, M.A.5    Taylor, J.W.6
  • 32
    • 0032807691 scopus 로고    scopus 로고
    • Clathrin assembly lymphoid myeloid leukemia (CALM) protein: Localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic
    • 25500, 10436022
    • Tebar F, Bohlander SK, Sorkin A. Clathrin assembly lymphoid myeloid leukemia (CALM) protein: Localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic. Mol Biol Cell 1999, 10:2687-2702. 25500, 10436022.
    • (1999) Mol Biol Cell , vol.10 , pp. 2687-2702
    • Tebar, F.1    Bohlander, S.K.2    Sorkin, A.3
  • 33
    • 38849199843 scopus 로고    scopus 로고
    • Evidence for CALM in directing VAMP2 trafficking
    • 10.1111/j.1600-0854.2007.00694.x, 18182011
    • Harel A, Wu F, Mattson MP, Morris CM, Yao PJ. Evidence for CALM in directing VAMP2 trafficking. Traffic 2008, 9:417-429. 10.1111/j.1600-0854.2007.00694.x, 18182011.
    • (2008) Traffic , vol.9 , pp. 417-429
    • Harel, A.1    Wu, F.2    Mattson, M.P.3    Morris, C.M.4    Yao, P.J.5
  • 34
    • 9644278100 scopus 로고    scopus 로고
    • Synaptic distribution of the endocytic accessory proteins AP180 and CALM
    • 10.1002/cne.20362, 15558718
    • Yao PJ, Petralia RS, Bushlin I, Wang Y, Furukawa K. Synaptic distribution of the endocytic accessory proteins AP180 and CALM. J Comp Neurol 2005, 481:58-69. 10.1002/cne.20362, 15558718.
    • (2005) J Comp Neurol , vol.481 , pp. 58-69
    • Yao, P.J.1    Petralia, R.S.2    Bushlin, I.3    Wang, Y.4    Furukawa, K.5
  • 35
    • 34250304714 scopus 로고    scopus 로고
    • Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling
    • 10.1074/jbc.M610146200, 17314098
    • Nizzari M, Venezia V, Repetto E, Caorsi V, Magrassi R, Gagliani MC, et al. Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling. J Biol Chem 2007, 282:13833-13844. 10.1074/jbc.M610146200, 17314098.
    • (2007) J Biol Chem , vol.282 , pp. 13833-13844
    • Nizzari, M.1    Venezia, V.2    Repetto, E.3    Caorsi, V.4    Magrassi, R.5    Gagliani, M.C.6
  • 36
    • 34249745769 scopus 로고    scopus 로고
    • GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers
    • 10.1016/j.neuron.2007.05.022, 2587162, 17553421
    • Reiman EM, Webster JA, Myers AJ, Hardy J, Dunckley T, Zismann VL, et al. GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers. Neuron 2007, 54:713-720. 10.1016/j.neuron.2007.05.022, 2587162, 17553421.
    • (2007) Neuron , vol.54 , pp. 713-720
    • Reiman, E.M.1    Webster, J.A.2    Myers, A.J.3    Hardy, J.4    Dunckley, T.5    Zismann, V.L.6
  • 37
    • 77955036445 scopus 로고    scopus 로고
    • Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals
    • 10.1093/hmg/ddq221, 2908469, 20534741
    • Corneveaux JJ, Myers AJ, Allen AN, Pruzin JJ, Ramirez M, Engel A, et al. Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum Mol Genet 2010, 19:3295-3301. 10.1093/hmg/ddq221, 2908469, 20534741.
    • (2010) Hum Mol Genet , vol.19 , pp. 3295-3301
    • Corneveaux, J.J.1    Myers, A.J.2    Allen, A.N.3    Pruzin, J.J.4    Ramirez, M.5    Engel, A.6
  • 38
    • 59249097049 scopus 로고    scopus 로고
    • Complement Receptor 1: Disease associations and therapeutic implications
    • 10.1016/j.molimm.2008.09.026, 19004497
    • Khera R, Das N. Complement Receptor 1: Disease associations and therapeutic implications. Mol Immunol 2009, 46:761-772. 10.1016/j.molimm.2008.09.026, 19004497.
    • (2009) Mol Immunol , vol.46 , pp. 761-772
    • Khera, R.1    Das, N.2
  • 39
    • 77952307991 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic loci associated with Alzheimer disease
    • 10.1001/jama.2010.574, 2989531, 20460622
    • Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010, 303:1832-1840. 10.1001/jama.2010.574, 2989531, 20460622.
    • (2010) JAMA , vol.303 , pp. 1832-1840
    • Seshadri, S.1    Fitzpatrick, A.L.2    Ikram, M.A.3    DeStefano, A.L.4    Gudnason, V.5    Boada, M.6
  • 40
    • 73349097586 scopus 로고    scopus 로고
    • AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling
    • 10.1038/ncb1986, 2788952, 19915558
    • Pant S, Sharma M, Patel K, Caplan S, Carr CM, Grant BD. AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling. Nat Cell Biol 2009, 11:1399-1410. 10.1038/ncb1986, 2788952, 19915558.
    • (2009) Nat Cell Biol , vol.11 , pp. 1399-1410
    • Pant, S.1    Sharma, M.2    Patel, K.3    Caplan, S.4    Carr, C.M.5    Grant, B.D.6
  • 41
    • 77955463899 scopus 로고    scopus 로고
    • Replication of CLU, CR1, and PICALM associations with alzheimer disease
    • 10.1001/archneurol.2010.147, 2919638, 20554627
    • Carrasquillo MM, Belbin O, Hunter TA, Ma L, Bisceglio GD, Zou F, et al. Replication of CLU, CR1, and PICALM associations with alzheimer disease. Arch Neurol 2010, 67:961-964. 10.1001/archneurol.2010.147, 2919638, 20554627.
    • (2010) Arch Neurol , vol.67 , pp. 961-964
    • Carrasquillo, M.M.1    Belbin, O.2    Hunter, T.A.3    Ma, L.4    Bisceglio, G.D.5    Zou, F.6
  • 42
    • 79955484414 scopus 로고    scopus 로고
    • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
    • 10.1038/ng.803, 21460840
    • Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet 2011, 43:429-35. 10.1038/ng.803, 21460840.
    • (2011) Nat Genet , vol.43 , pp. 429-435
    • Hollingworth, P.1    Harold, D.2    Sims, R.3    Gerrish, A.4    Lambert, J.C.5    Carrasquillo, M.M.6
  • 43
    • 79955464911 scopus 로고    scopus 로고
    • Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
    • 10.1038/ng.801, 21460841
    • Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet 2011, 43:436-41. 10.1038/ng.801, 21460841.
    • (2011) Nat Genet , vol.43 , pp. 436-441
    • Naj, A.C.1    Jun, G.2    Beecham, G.W.3    Wang, L.S.4    Vardarajan, B.N.5    Buros, J.6
  • 44
    • 0033836368 scopus 로고    scopus 로고
    • Association of an interleukin 1 alpha polymorphism with Alzheimer's disease
    • Du Y, Dodel RC, Eastwood BJ, Bales KR, Gao F, Lohmüller F, et al. Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. Neurology 2000, 55:480-483.
    • (2000) Neurology , vol.55 , pp. 480-483
    • Du, Y.1    Dodel, R.C.2    Eastwood, B.J.3    Bales, K.R.4    Gao, F.5    Lohmüller, F.6
  • 45
    • 79951473930 scopus 로고    scopus 로고
    • The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease
    • 10.1001/archgenpsychiatry.2010.194, 21300947
    • Voineskos AN, Lerch JP, Felsky D, Shaikh S, Rajji TK, Miranda D, et al. The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease. Arch Gen Psychiatry 2011, 68:198-206. 10.1001/archgenpsychiatry.2010.194, 21300947.
    • (2011) Arch Gen Psychiatry , vol.68 , pp. 198-206
    • Voineskos, A.N.1    Lerch, J.P.2    Felsky, D.3    Shaikh, S.4    Rajji, T.K.5    Miranda, D.6
  • 46
    • 79551474326 scopus 로고    scopus 로고
    • SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk
    • 10.1002/ana.22308, 21280075
    • Reitz C, Tokuhiro S, Clark LN, Conrad C, Vonsattel JP, Hazrati LN, et al. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. Ann Neurol 2011, 69:47-64. 10.1002/ana.22308, 21280075.
    • (2011) Ann Neurol , vol.69 , pp. 47-64
    • Reitz, C.1    Tokuhiro, S.2    Clark, L.N.3    Conrad, C.4    Vonsattel, J.P.5    Hazrati, L.N.6
  • 47
    • 78751635081 scopus 로고    scopus 로고
    • Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort
    • 10.1212/WNL.0b013e318204a397, 21123754
    • Kim S, Swaminathan S, Shen L, Risacher SL, Nho K, Foroud T, et al. Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort. Neurology 2011, 76:69-79. 10.1212/WNL.0b013e318204a397, 21123754.
    • (2011) Neurology , vol.76 , pp. 69-79
    • Kim, S.1    Swaminathan, S.2    Shen, L.3    Risacher, S.L.4    Nho, K.5    Foroud, T.6
  • 48
    • 70349481490 scopus 로고    scopus 로고
    • Systematic review by meta-analyses on the possible role of TNF-alpha polymorphisms in association with Alzheimer's disease
    • 10.1016/j.brainresrev.2009.05.001, 19445962
    • Di Bona D, Candore G, Franceschi C, Licastro F, Colonna-Romano G, Cammà C, et al. Systematic review by meta-analyses on the possible role of TNF-alpha polymorphisms in association with Alzheimer's disease. Brain Res Rev 2009, 61:60-68. 10.1016/j.brainresrev.2009.05.001, 19445962.
    • (2009) Brain Res Rev , vol.61 , pp. 60-68
    • Di Bona, D.1    Candore, G.2    Franceschi, C.3    Licastro, F.4    Colonna-Romano, G.5    Cammà, C.6
  • 49
    • 65249159879 scopus 로고    scopus 로고
    • Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
    • 10.1002/ana.21610, 2696350, 19296504
    • Shaw LM, Vanderstichele H, Knapik-Czajka M, Clark CM, Aisen PS, Petersen RC, et al. Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects. Ann Neurol 2009, 65:403-413. 10.1002/ana.21610, 2696350, 19296504.
    • (2009) Ann Neurol , vol.65 , pp. 403-413
    • Shaw, L.M.1    Vanderstichele, H.2    Knapik-Czajka, M.3    Clark, C.M.4    Aisen, P.S.5    Petersen, R.C.6
  • 50
    • 35948933394 scopus 로고    scopus 로고
    • Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
    • 10.1038/nm1653, 17934472
    • Ray S, Britschgi M, Herbert C, Takeda-Uchimura Y, Boxer A, Blennow K, et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat Med 2007, 13:1359-1362. 10.1038/nm1653, 17934472.
    • (2007) Nat Med , vol.13 , pp. 1359-1362
    • Ray, S.1    Britschgi, M.2    Herbert, C.3    Takeda-Uchimura, Y.4    Boxer, A.5    Blennow, K.6
  • 51
    • 58449133739 scopus 로고    scopus 로고
    • S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10
    • 10.1371/journal.pone.0004183, 2613557, 19159013
    • Qin W, Ho L, Wang J, Peskind E, Pasinetti GM. S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. PLoS One 2009, 4:e4183. 10.1371/journal.pone.0004183, 2613557, 19159013.
    • (2009) PLoS One , vol.4
    • Qin, W.1    Ho, L.2    Wang, J.3    Peskind, E.4    Pasinetti, G.M.5
  • 52
    • 19944432197 scopus 로고    scopus 로고
    • Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents
    • 10.1074/mcp.M400129-MCP200, 15385600
    • Ross PL, Huang YN, Marchese JN, Williamson B, Parker K, Hattan S, et al. Multiplexed protein quantitation in Saccharomyces cerevisiae using amine-reactive isobaric tagging reagents. Mol Cell Proteomics 2004, 3:1154-69. 10.1074/mcp.M400129-MCP200, 15385600.
    • (2004) Mol Cell Proteomics , vol.3 , pp. 1154-1169
    • Ross, P.L.1    Huang, Y.N.2    Marchese, J.N.3    Williamson, B.4    Parker, K.5    Hattan, S.6
  • 53
    • 12444345515 scopus 로고    scopus 로고
    • Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS
    • 10.1021/ac0262560, 12713048
    • Thompson A, Schäfer J, Kuhn K, Kienle S, Schwarz J, Schmidt G, et al. Tandem mass tags: a novel quantification strategy for comparative analysis of complex protein mixtures by MS/MS. Anal Chem 2003, 75:1895-904. 10.1021/ac0262560, 12713048.
    • (2003) Anal Chem , vol.75 , pp. 1895-1904
    • Thompson, A.1    Schäfer, J.2    Kuhn, K.3    Kienle, S.4    Schwarz, J.5    Schmidt, G.6
  • 54
    • 0032875697 scopus 로고    scopus 로고
    • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    • 10.1038/13690, 10504701
    • Gygi SP, Rist B, Gerber SA, Turecek F, Gelb MH, Aebersold R. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat Biotechnol 1999, 17:994-999. 10.1038/13690, 10504701.
    • (1999) Nat Biotechnol , vol.17 , pp. 994-999
    • Gygi, S.P.1    Rist, B.2    Gerber, S.A.3    Turecek, F.4    Gelb, M.H.5    Aebersold, R.6
  • 55
    • 13244260803 scopus 로고    scopus 로고
    • Novel strategy for quantitative proteomics using isotope-coded protein labels
    • Schmidt A, Kellermann J, Lottspeich F. novel strategy for quantitative proteomics using isotope-coded protein labels. A Proteomics 2005, 5:4-15.
    • (2005) A Proteomics , vol.5 , pp. 4-15
    • Schmidt, A.1    Kellermann, J.2    Lottspeich, F.3
  • 56
    • 37849014569 scopus 로고    scopus 로고
    • Alzheimer's disease diagnosis in individual subjects using structural MR images: validation studies
    • 10.1016/j.neuroimage.2007.09.073, 2390889, 18054253
    • Vemuri P, Gunter JL, Senjem ML, Whitwell JL, Kantarci K, Knopman DS, et al. Alzheimer's disease diagnosis in individual subjects using structural MR images: validation studies. Neuroimage 2008, 39:1186-97. 10.1016/j.neuroimage.2007.09.073, 2390889, 18054253.
    • (2008) Neuroimage , vol.39 , pp. 1186-1197
    • Vemuri, P.1    Gunter, J.L.2    Senjem, M.L.3    Whitwell, J.L.4    Kantarci, K.5    Knopman, D.S.6
  • 57
    • 54249139075 scopus 로고    scopus 로고
    • Tensor-based morphometry as a neuroimaging biomarker for Alzheimer's disease: an MRI study of 676 AD, MCI, and normal subjects
    • 10.1016/j.neuroimage.2008.07.013, 18691658
    • Hua X, Leow AD, Parikshak N, Lee S, Chiang MC, Toga AW, et al. Tensor-based morphometry as a neuroimaging biomarker for Alzheimer's disease: an MRI study of 676 AD, MCI, and normal subjects. Neuroimage 2008, 43:458-69. 10.1016/j.neuroimage.2008.07.013, 18691658.
    • (2008) Neuroimage , vol.43 , pp. 458-469
    • Hua, X.1    Leow, A.D.2    Parikshak, N.3    Lee, S.4    Chiang, M.C.5    Toga, A.W.6
  • 58
    • 78650413213 scopus 로고    scopus 로고
    • Diagnosis and biomarkers of predementia in Alzheimer's disease
    • 10.1186/1741-7015-8-89, 3022870, 21176189
    • Forlenza OV, Diniz BS, Gattaz WF. Diagnosis and biomarkers of predementia in Alzheimer's disease. BMC Med 2010, 8:89. 10.1186/1741-7015-8-89, 3022870, 21176189.
    • (2010) BMC Med , vol.8 , pp. 89
    • Forlenza, O.V.1    Diniz, B.S.2    Gattaz, W.F.3
  • 59
    • 59849112270 scopus 로고    scopus 로고
    • Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease
    • 10.1007/s00702-008-0177-6, 19142572
    • Welge V, Fiege O, Lewczuk P, Mollenhauer B, Esselmann H, Klafki HW, et al. Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease. Journal of Neural Transmission 2009, 116:203-12. 10.1007/s00702-008-0177-6, 19142572.
    • (2009) Journal of Neural Transmission , vol.116 , pp. 203-212
    • Welge, V.1    Fiege, O.2    Lewczuk, P.3    Mollenhauer, B.4    Esselmann, H.5    Klafki, H.W.6
  • 60
    • 77953029039 scopus 로고    scopus 로고
    • Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment
    • 10.1007/s00401-010-0667-0, 2880811, 20232070
    • Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, et al. Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment. Acta Neuropathol 2010, 119:669-78. 10.1007/s00401-010-0667-0, 2880811, 20232070.
    • (2010) Acta Neuropathol , vol.119 , pp. 669-678
    • Hu, W.T.1    Chen-Plotkin, A.2    Arnold, S.E.3    Grossman, M.4    Clark, C.M.5    Shaw, L.M.6
  • 61
    • 77955483685 scopus 로고    scopus 로고
    • Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects
    • 10.1016/j.jalz.2010.03.008, 2867838, 20451871
    • Trojanowski JQ, Vandeerstichele H, Korecka M, Clark CM, Aisen PS, Petersen RC, et al. Update on the biomarker core of the Alzheimer's Disease Neuroimaging Initiative subjects. Alzheimers Dement 2010, 6:230-238. 10.1016/j.jalz.2010.03.008, 2867838, 20451871.
    • (2010) Alzheimers Dement , vol.6 , pp. 230-238
    • Trojanowski, J.Q.1    Vandeerstichele, H.2    Korecka, M.3    Clark, C.M.4    Aisen, P.S.5    Petersen, R.C.6
  • 62
    • 75149128305 scopus 로고    scopus 로고
    • Alzheimer's disease and CSF biomarkers: key challenges for broad clinical applications
    • 10.2217/bmm.09.65, 20477711
    • Mattsson N, Zetterberg H. Alzheimer's disease and CSF biomarkers: key challenges for broad clinical applications. Biomark Med 2009, 3:735-737. 10.2217/bmm.09.65, 20477711.
    • (2009) Biomark Med , vol.3 , pp. 735-737
    • Mattsson, N.1    Zetterberg, H.2
  • 63
    • 79955953179 scopus 로고    scopus 로고
    • A novel pathway for amyloid precursor protein processing
    • 10.1016/j.neurobiolaging.2009.06.002, 19604603
    • Portelius E, Price E, Brinkmalm G, Stiteler M, Olsson M, Persson R, et al. A novel pathway for amyloid precursor protein processing. Neurobiol Aging 2011, 32:1090-1098. 10.1016/j.neurobiolaging.2009.06.002, 19604603.
    • (2011) Neurobiol Aging , vol.32 , pp. 1090-1098
    • Portelius, E.1    Price, E.2    Brinkmalm, G.3    Stiteler, M.4    Olsson, M.5    Persson, R.6
  • 64
    • 44649183443 scopus 로고    scopus 로고
    • Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides
    • 10.1159/000119457, 18309230
    • Höglund K, Hansson O, Buchhave P, Zetterberg H, Lewczuk P, Londos E, et al. Prediction of Alzheimer's disease using a cerebrospinal fluid pattern of C-terminally truncated beta-amyloid peptides. Neurodegener Dis 2008, 5:268-76. 10.1159/000119457, 18309230.
    • (2008) Neurodegener Dis , vol.5 , pp. 268-276
    • Höglund, K.1    Hansson, O.2    Buchhave, P.3    Zetterberg, H.4    Lewczuk, P.5    Londos, E.6
  • 65
    • 54049133348 scopus 로고    scopus 로고
    • The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients
    • 10.1373/clinchem.2008.104497, 2672199, 18703769
    • Lee JM, Blennow K, Andreasen N, Laterza O, Modur V, Olander J, et al. The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients. Clin Chem 2008, 54:1617-23. 10.1373/clinchem.2008.104497, 2672199, 18703769.
    • (2008) Clin Chem , vol.54 , pp. 1617-1623
    • Lee, J.M.1    Blennow, K.2    Andreasen, N.3    Laterza, O.4    Modur, V.5    Olander, J.6
  • 66
    • 17744366169 scopus 로고    scopus 로고
    • The cerebrospinal fluid levels of tau, growth-associated protein-43 and soluble amyloid precursor protein correlate in Alzheimer's disease, reflecting a common pathophysiological process
    • 10.1159/000051268, 11351137
    • Sjögren M, Davidsson P, Gottfries J, Vanderstichele H, Edman A, Vanmechelen E, et al. The cerebrospinal fluid levels of tau, growth-associated protein-43 and soluble amyloid precursor protein correlate in Alzheimer's disease, reflecting a common pathophysiological process. Dement Geriatr Cogn Disord 2001, 12:257-64. 10.1159/000051268, 11351137.
    • (2001) Dement Geriatr Cogn Disord , vol.12 , pp. 257-264
    • Sjögren, M.1    Davidsson, P.2    Gottfries, J.3    Vanderstichele, H.4    Edman, A.5    Vanmechelen, E.6
  • 67
    • 70449628747 scopus 로고    scopus 로고
    • Identification of the apolipoprotein E4 isoform in cerebrospinal fluid with preparative two-dimensional electrophoresis and matrix assisted laser desorption/ionization-time of flight-mass spectrometry
    • 10.1002/1522-2683(200105)22:9<1834::AID-ELPS1834>3.0.CO;2-V, 11425239
    • Hesse C, Nilsson CL, Blennow K, Davidsson P. Identification of the apolipoprotein E4 isoform in cerebrospinal fluid with preparative two-dimensional electrophoresis and matrix assisted laser desorption/ionization-time of flight-mass spectrometry. Electrophoresis 2001, 22:1834-1837. 10.1002/1522-2683(200105)22:9<1834::AID-ELPS1834>3.0.CO;2-V, 11425239.
    • (2001) Electrophoresis , vol.22 , pp. 1834-1837
    • Hesse, C.1    Nilsson, C.L.2    Blennow, K.3    Davidsson, P.4
  • 68
    • 0037117721 scopus 로고    scopus 로고
    • Proteome analysis of cerebrospinal fluid proteins in Alzheimer patients
    • 10.1097/00001756-200204160-00015, 11973456
    • Davidsson P, Westman-Brinkmalm A, Nilsson CL, Lindbjer M, Paulson L, et al. Proteome analysis of cerebrospinal fluid proteins in Alzheimer patients. Neuroreport 2002, 13:611-615. 10.1097/00001756-200204160-00015, 11973456.
    • (2002) Neuroreport , vol.13 , pp. 611-615
    • Davidsson, P.1    Westman-Brinkmalm, A.2    Nilsson, C.L.3    Lindbjer, M.4    Paulson, L.5
  • 70
    • 34147221048 scopus 로고    scopus 로고
    • Multiplexed proteomic analysis of oxidation and concentrations of cerebrospinal fluid proteins in Alzheimer disease
    • 10.1373/clinchem.2006.078014, 17289803
    • Korolainen MA, Nyman TA, Nyyssönen P, Hartikainen ES, Pirttilä T. Multiplexed proteomic analysis of oxidation and concentrations of cerebrospinal fluid proteins in Alzheimer disease. Clin Chem 2007, 53:657-65. 10.1373/clinchem.2006.078014, 17289803.
    • (2007) Clin Chem , vol.53 , pp. 657-665
    • Korolainen, M.A.1    Nyman, T.A.2    Nyyssönen, P.3    Hartikainen, E.S.4    Pirttilä, T.5
  • 71
    • 44549087658 scopus 로고    scopus 로고
    • Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer's disease patients and healthy individuals
    • 10.1007/s11064-008-9588-x, 18288611
    • Sihlbom C, Davidsson P, Sjögren M, Wahlund LO, Nilsson CL. Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer's disease patients and healthy individuals. Neurochem Res 2008, 33:1332-40. 10.1007/s11064-008-9588-x, 18288611.
    • (2008) Neurochem Res , vol.33 , pp. 1332-1340
    • Sihlbom, C.1    Davidsson, P.2    Sjögren, M.3    Wahlund, L.O.4    Nilsson, C.L.5
  • 73
    • 57349192880 scopus 로고    scopus 로고
    • Apolipoprotein E highly correlates with AbetaPP- and tau-related markers in human cerebrospinal fluid
    • 2667787, 18997294
    • Vuletic S, Li G, Peskind ER, Kennedy H, Marcovina SM, Leverenz JB, et al. Apolipoprotein E highly correlates with AbetaPP- and tau-related markers in human cerebrospinal fluid. J Alzheimers Dis 2008, 15:409-17. 2667787, 18997294.
    • (2008) J Alzheimers Dis , vol.15 , pp. 409-417
    • Vuletic, S.1    Li, G.2    Peskind, E.R.3    Kennedy, H.4    Marcovina, S.M.5    Leverenz, J.B.6
  • 74
    • 35348817935 scopus 로고    scopus 로고
    • F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease
    • 10.1007/s12031-007-0044-1, 17901555
    • Montine TJ, Quinn J, Kaye J, Morrow JD. F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease. J Mol Neurosci 2007, 33:114-119. 10.1007/s12031-007-0044-1, 17901555.
    • (2007) J Mol Neurosci , vol.33 , pp. 114-119
    • Montine, T.J.1    Quinn, J.2    Kaye, J.3    Morrow, J.D.4
  • 75
    • 74149091007 scopus 로고    scopus 로고
    • In vivo oxidative stress in brain of Alzheimer disease transgenic mice: requirement for methionine 35 in amyloid β-peptide of APP
    • 10.1016/j.freeradbiomed.2009.10.035, 2818480, 19854267
    • Butterfield DA, Galvan V, Lange MB, Tang H, Sowell RA, Spilman P, et al. In vivo oxidative stress in brain of Alzheimer disease transgenic mice: requirement for methionine 35 in amyloid β-peptide of APP. Free Radic Biol Med 2010, 48:136-144. 10.1016/j.freeradbiomed.2009.10.035, 2818480, 19854267.
    • (2010) Free Radic Biol Med , vol.48 , pp. 136-144
    • Butterfield, D.A.1    Galvan, V.2    Lange, M.B.3    Tang, H.4    Sowell, R.A.5    Spilman, P.6
  • 76
    • 0032868874 scopus 로고    scopus 로고
    • Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia
    • 10.1023/A:1020568013953, 10471976
    • Tarkowski E, Blennow K, Wallin A, Tarkowski A. Intracerebral production of tumor necrosis factor-alpha, a local neuroprotective agent, in Alzheimer disease and vascular dementia. J Clin Immunol 1999, 19:223-230. 10.1023/A:1020568013953, 10471976.
    • (1999) J Clin Immunol , vol.19 , pp. 223-230
    • Tarkowski, E.1    Blennow, K.2    Wallin, A.3    Tarkowski, A.4
  • 77
    • 24944522343 scopus 로고    scopus 로고
    • Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias
    • 10.1159/000089137, 16244482
    • Blasko I, Lederer W, Oberbauer H, Walch T, Kemmler G, Hinterhuber H, et al. Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias. Dement Geriatr Cogn Disord 2006, 21:9-15. 10.1159/000089137, 16244482.
    • (2006) Dement Geriatr Cogn Disord , vol.21 , pp. 9-15
    • Blasko, I.1    Lederer, W.2    Oberbauer, H.3    Walch, T.4    Kemmler, G.5    Hinterhuber, H.6
  • 78
    • 33645731581 scopus 로고    scopus 로고
    • Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease
    • 10.1001/archneur.63.4.538, 16606766
    • Galimberti D, Schoonenboom N, Scheltens P, Fenoglio C, Bouwman F, Venturelli E, et al. Intrathecal chemokine synthesis in mild cognitive impairment and Alzheimer disease. Arch Neurol 2006, 63:538-43. 10.1001/archneur.63.4.538, 16606766.
    • (2006) Arch Neurol , vol.63 , pp. 538-543
    • Galimberti, D.1    Schoonenboom, N.2    Scheltens, P.3    Fenoglio, C.4    Bouwman, F.5    Venturelli, E.6
  • 79
    • 0042421736 scopus 로고    scopus 로고
    • Cerebrospinal fluid markers in dementia with lewy bodies compared with Alzheimer disease
    • 10.1001/archneur.60.9.1218, 12975286
    • Gómez-Tortosa E, Gonzalo I, Fanjul S, Sainz MJ, Cantarero S, Cemillán C. Cerebrospinal fluid markers in dementia with lewy bodies compared with Alzheimer disease. Arch Neurol 2003, 60:1218-1222. 10.1001/archneur.60.9.1218, 12975286.
    • (2003) Arch Neurol , vol.60 , pp. 1218-1222
    • Gómez-Tortosa, E.1    Gonzalo, I.2    Fanjul, S.3    Sainz, M.J.4    Cantarero, S.5    Cemillán, C.6
  • 80
    • 33745252827 scopus 로고    scopus 로고
    • Increased intrathecal TGF-beta1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients
    • 10.1007/s10072-006-0562-6, 16688597
    • Rota E, Bellone G, Rocca P, Bergamasco B, Emanuelli G, Ferrero P. Increased intrathecal TGF-beta1, but not IL-12, IFN-gamma and IL-10 levels in Alzheimer's disease patients. Neurol Sci 2006, 27:33-39. 10.1007/s10072-006-0562-6, 16688597.
    • (2006) Neurol Sci , vol.27 , pp. 33-39
    • Rota, E.1    Bellone, G.2    Rocca, P.3    Bergamasco, B.4    Emanuelli, G.5    Ferrero, P.6
  • 81
    • 79955506338 scopus 로고    scopus 로고
    • Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease
    • 10.1371/journal.pone.0016032, 3020224, 21264269
    • Perrin RJ, Craig-Schapiro R, Malone JP, Shah AR, Gilmore P, Davis AE, et al. Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease. PLoS One 2011, 6:e16032. 10.1371/journal.pone.0016032, 3020224, 21264269.
    • (2011) PLoS One , vol.6
    • Perrin, R.J.1    Craig-Schapiro, R.2    Malone, J.P.3    Shah, A.R.4    Gilmore, P.5    Davis, A.E.6
  • 82
    • 73949119890 scopus 로고    scopus 로고
    • Inhibition of phospholipase A2 increases tau phosphorylation at Ser214 in embryonic rat hippocampal neurons
    • 10.1016/j.plefa.2009.07.006, 19726172
    • De-Paula VJ, Schaeffer EL, Talib LL, Gattaz WF, Forlenza OV. Inhibition of phospholipase A2 increases tau phosphorylation at Ser214 in embryonic rat hippocampal neurons. Prostaglandins Leukot Essent Fatty Acids 2010, 82:57-60. 10.1016/j.plefa.2009.07.006, 19726172.
    • (2010) Prostaglandins Leukot Essent Fatty Acids , vol.82 , pp. 57-60
    • De-Paula, V.J.1    Schaeffer, E.L.2    Talib, L.L.3    Gattaz, W.F.4    Forlenza, O.V.5
  • 83
    • 0033590975 scopus 로고    scopus 로고
    • High levels of circulating Abeta42 are sequestered by plasma proteins in Alzheimer's disease
    • 10.1006/bbrc.1999.0552, 10208861
    • Kuo YM, Emmerling MR, Lampert HC, Hempelman SR, Kokjohn TA. High levels of circulating Abeta42 are sequestered by plasma proteins in Alzheimer's disease. Biochem Biophys Res Commun 1999, 257:787-91. 10.1006/bbrc.1999.0552, 10208861.
    • (1999) Biochem Biophys Res Commun , vol.257 , pp. 787-791
    • Kuo, Y.M.1    Emmerling, M.R.2    Lampert, H.C.3    Hempelman, S.R.4    Kokjohn, T.A.5
  • 84
    • 0036250622 scopus 로고    scopus 로고
    • Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid
    • 10.1016/S0197-4580(01)00328-1, 12009495
    • Teunissen CE, de Vente J, Steinbusch HW, De Bruijn C. Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid. Neurobiol Aging 2002, 23(4):485-508. 10.1016/S0197-4580(01)00328-1, 12009495.
    • (2002) Neurobiol Aging , vol.23 , Issue.4 , pp. 485-508
    • Teunissen, C.E.1    de Vente, J.2    Steinbusch, H.W.3    De Bruijn, C.4
  • 85
    • 34249784822 scopus 로고    scopus 로고
    • Inflammatory markers and the risk of Alzheimer disease: the Framingham Study
    • 10.1212/01.wnl.0000263217.36439.da, 17536046
    • Tan ZS, Beiser AS, Vasan RS, Roubenoff R, Dinarello CA, Harris TB, et al. Inflammatory markers and the risk of Alzheimer disease: the Framingham Study. Neurology 2007, 68:1902-8. 10.1212/01.wnl.0000263217.36439.da, 17536046.
    • (2007) Neurology , vol.68 , pp. 1902-1908
    • Tan, Z.S.1    Beiser, A.S.2    Vasan, R.S.3    Roubenoff, R.4    Dinarello, C.A.5    Harris, T.B.6
  • 86
    • 36148965162 scopus 로고    scopus 로고
    • Use of proteomic approaches to identify disease biomarkers
    • 10.1016/S1474-4422(07)70276-4, 18031700
    • Teunissen CE, Scheltens P. Use of proteomic approaches to identify disease biomarkers. Lancet Neurol 2007, 6(12):1036-7. 10.1016/S1474-4422(07)70276-4, 18031700.
    • (2007) Lancet Neurol , vol.6 , Issue.12 , pp. 1036-1037
    • Teunissen, C.E.1    Scheltens, P.2
  • 87
    • 2442684094 scopus 로고    scopus 로고
    • Cholesterol and APOE genotype interact to influence Alzheimer disease progression
    • Evans RM, Hui S, Perkins A, Lahiri DK, Poirier J, Farlow MR. Cholesterol and APOE genotype interact to influence Alzheimer disease progression. Neurology 2004, 62:1869-71.
    • (2004) Neurology , vol.62 , pp. 1869-1871
    • Evans, R.M.1    Hui, S.2    Perkins, A.3    Lahiri, D.K.4    Poirier, J.5    Farlow, M.R.6
  • 88
    • 48649110601 scopus 로고    scopus 로고
    • Cholesterol as a risk factor for dementia and cognitive decline: a systematic review of prospective studies with meta-analysis
    • Anstey KJ, Lipnicki DM, Low LF. Cholesterol as a risk factor for dementia and cognitive decline: a systematic review of prospective studies with meta-analysis. Am J Geriatr Psychiatry 2008, 16:343-54.
    • (2008) Am J Geriatr Psychiatry , vol.16 , pp. 343-354
    • Anstey, K.J.1    Lipnicki, D.M.2    Low, L.F.3
  • 89
    • 71849106317 scopus 로고    scopus 로고
    • Soluble cell adhesion molecules in monocytes of Alzheimer's disease and mild cognitive impairment
    • 10.1016/j.exger.2009.10.005, 19836440
    • Hochstrasser T, Weiss E, Marksteiner J, Humpel C. Soluble cell adhesion molecules in monocytes of Alzheimer's disease and mild cognitive impairment. Exp Gerontol 2010, 45:70-74. 10.1016/j.exger.2009.10.005, 19836440.
    • (2010) Exp Gerontol , vol.45 , pp. 70-74
    • Hochstrasser, T.1    Weiss, E.2    Marksteiner, J.3    Humpel, C.4
  • 90
    • 72149095179 scopus 로고    scopus 로고
    • Blood-based biomarkers of microvascular pathology in Alzheimer's disease
    • 10.1016/j.exger.2009.09.005, 2815204, 19782124
    • Ewers M, Mielke MM, Hampel H. Blood-based biomarkers of microvascular pathology in Alzheimer's disease. Exp Gerontol 2010, 45:75-79. 10.1016/j.exger.2009.09.005, 2815204, 19782124.
    • (2010) Exp Gerontol , vol.45 , pp. 75-79
    • Ewers, M.1    Mielke, M.M.2    Hampel, H.3
  • 91
    • 70149093189 scopus 로고    scopus 로고
    • Postischemic PKC activation rescues retrograde and anterograde long-term memory
    • 10.1073/pnas.0907842106, 2732881, 19667190
    • Sun MK, Hongpaisan J, Alkon DL. Postischemic PKC activation rescues retrograde and anterograde long-term memory. Proc Natl Acad Sci USA 2009, 106:14676-80. 10.1073/pnas.0907842106, 2732881, 19667190.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 14676-14680
    • Sun, M.K.1    Hongpaisan, J.2    Alkon, D.L.3
  • 92
    • 71849092119 scopus 로고    scopus 로고
    • Protein kinase C as a peripheral biomarker for Alzheimer's disease
    • 10.1016/j.exger.2009.10.015, 19895879
    • de Barry J, Liégeois CM, Janoshazi A. Protein kinase C as a peripheral biomarker for Alzheimer's disease. Exp Gerontol 2010, 45:64-69. 10.1016/j.exger.2009.10.015, 19895879.
    • (2010) Exp Gerontol , vol.45 , pp. 64-69
    • de Barry, J.1    Liégeois, C.M.2    Janoshazi, A.3
  • 93
    • 0034709459 scopus 로고    scopus 로고
    • Dual effects of PKNalpha and protein kinase C on phosphorylation of tau protein by glycogen synthase kinase-3beta
    • 10.1006/bbrc.2000.2926, 10873588
    • Isagawa T, Mukai H, Oishi K, Taniguchi T, Hasegawa H, Kawamata T, et al. Dual effects of PKNalpha and protein kinase C on phosphorylation of tau protein by glycogen synthase kinase-3beta. Biochem Biophys Res Commun 2000, 273:209-12. 10.1006/bbrc.2000.2926, 10873588.
    • (2000) Biochem Biophys Res Commun , vol.273 , pp. 209-212
    • Isagawa, T.1    Mukai, H.2    Oishi, K.3    Taniguchi, T.4    Hasegawa, H.5    Kawamata, T.6
  • 94
    • 77249179997 scopus 로고    scopus 로고
    • An update on clinical proteomics in Alzheimer's research
    • 10.1111/j.1471-4159.2009.06558.x, 20050976
    • Korolainen MA, Nyman TA, Aittokallio T, Pirttilä T. An update on clinical proteomics in Alzheimer's research. J Neurochem 2010, 112:1386-414. 10.1111/j.1471-4159.2009.06558.x, 20050976.
    • (2010) J Neurochem , vol.112 , pp. 1386-1414
    • Korolainen, M.A.1    Nyman, T.A.2    Aittokallio, T.3    Pirttilä, T.4


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