Helicobacter pylori vacuolating cytotoxin A (VacA) engages the mitochondrial fission machinery to induce host cell death

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 38, 2011, Pages 16032-16037

  Jain, Prashant ^a   Luo, Zhao Qing ^b   Blanke, Steven R ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

Cytochrome c; Gastric cancer; Gastric ulcer; Mitochondrial dynamics; Toxin

Indexed keywords

BACTERIAL PROTEIN; DYNAMIN I; PROTEIN BAX; UNCLASSIFIED DRUG; VACUOLATING CYTOTOXIN A;

ARTICLE; CELL DEATH; CELL STRAIN; HELICOBACTER PYLORI; HOST CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BACTERIAL PROTEINS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; CYTOCHROMES C; FIBROBLASTS; FLOW CYTOMETRY; GREEN FLUORESCENT PROTEINS; GTP PHOSPHOHYDROLASES; HELA CELLS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HOST-PATHOGEN INTERACTIONS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUTATION; STOMACH NEOPLASMS;

HELICOBACTER PYLORI;

EID: 80053139817     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105175108     Document Type: Article

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