Hepatitis E virus ORF2 protein activates the pro-apoptotic gene CHOP and anti-apoptotic heat shock proteins

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  John, Lijo ^a   Thomas, Saijo ^a,b   Herchenröder, Ottmar ^a   Pützer, Brigitte M ^a   Schaefer, Stephan ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; CAPSID PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70B'; HEAT SHOCK PROTEIN 72; INITIATION FACTOR 2ALPHA; MESSENGER RNA; OPEN READING FRAME 2 PROTEIN; PROTEIN BAX; UNCLASSIFIED DRUG; DDIT3 PROTEIN, HUMAN; HEAT SHOCK PROTEIN 70; HSP70B' PROTEIN, HUMAN; INITIATION FACTOR 2; ORF2 PROTEIN, HEPATITIS E VIRUS; VIRUS PROTEIN;

AMINO ACID RESPONSE ELEMENT; APOPTOSIS; ARTICLE; CHOP GENE; DNA RESPONSIVE ELEMENT; ENDOPLASMIC RETICULUM STRESS; ENDOPLASMIC RETICULUM STRESS RESPONSE ELEMENT; GENE; GENE ACTIVATION; HEPATITIS E VIRUS; MICROARRAY ANALYSIS; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RNA TRANSLATION; CELL LINE; DNA MICROARRAY; GENETICS; HUMAN; IMMUNOPRECIPITATION; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EUKARYOTA; HEPATITIS E VIRUS; MIRIDAE; RNA VIRUSES;

ACTIVATING TRANSCRIPTION FACTOR 4; BLOTTING, WESTERN; CELL LINE; EUKARYOTIC INITIATION FACTOR-2; HEPATITIS E VIRUS; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HSP72 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPRECIPITATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REAL-TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTOR CHOP; VIRAL PROTEINS;

EID: 80053097433     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025378     Document Type: Article

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