Egg allergens

Chemical and Biological Properties of Food Allergens

Volumn , Issue , 2009, Pages 213-222

  Baumgartner, Sabine ^a   Schubert Ullrich, Patricia ^a  

^a UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIES; PROTEINS;

ADVERSE REACTIONS; ALLERGIC REACTIONS; ALLERGIC SYMPTOMS; EGG ALLERGY; IGE BINDINGS; ORAL EXPOSURE; PROTEIN LEVEL; THRESHOLD DOSE;

ALLERGENS;

EID: 80053052942     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (60)

1. Anet, J., Back, J.F., Baker, R.S., Barnett, D., Burley, R.W., Howden, M.E. 1985. Allergens in the white and yolk of hen’s egg. A study of IgE binding by egg proteins. Int Arch Allergy Appl Immunol 77:364–371.
2. Anibarro Bausela, B., Besler, M., Rancé, F., Szépfalusi, Z. 2000. Allergen data collection— Update: Bird-egg syndrome. Internet Symp Food Allergens 2(5):1–12. Available at: http://www.food-allergens.de.
3. Anton, M., Martinet, V., Dalgalarrondo, M., Beaumal, V., David-Briand, E., Rabesona, H. 2003. Chemical and structural characterisation of low-density lipoproteins purified from hen egg yolk. Food Chem 83:175–183.
4. Astwood, J.D., Leach, L.N., Fuchs, R.L. 1996. Stability of food allergens to digestion in vitro. Nat Biotechnol 14:1269–1273.
5. Awade, A.C. 1996. On hen egg fractionation: Applications of liquid chromatography to the isolation and the purification of hen egg white and egg yolk proteins. Z Lebensm Unters Forsch 202:1–14.
6. Awade, A.C., Efstathiou, T. 1999. Comparison of three liquid chromatographic methods for egg-white protein analysis. J Chromatogr B 723:69–74.
7. Bernhisel-Broadbent, J., Dintzis, H.M., Dintzis, R.Z., Sampson, H.A. 1994. Allergenicity and antigenicity of chicken egg ovomucoid (Gal d III) compared with ovalbumin (Gal d I) in children with egg allergy and in mice. J Allergy Clin Immunol 93:1047–1059.
8. Besler, M. 1999. Allergen data collection—Bird-egg syndrome (egg yolk, feathers). Internet Symp Food Allergens 1(2):81–92. Available at: http://www.food-allergens.de.
9. Besler, M., Mine, Y. 1999. Major hen’s egg white allergen: Ovomucoid (Gal d 1). Internet Symp Food Allergens 1(4):137–146. Available at: http://www.food-allergens.de.
10. Besler, M., Steinhart, H., Paschke, A. 1997. Allergenicity of hen’s egg-white proteins: IgE binding of native and deglycosylated ovomucoid. Food Agric Immunol 9:277–288.
11. Besler, M., Steinhart, H., Paschke, A. 1998. Immunological characterization of egg white allergens collected by capillary electrophoresis. Food Agric Immunol 10:157–160.
12. Besler, M., Steinhart, H., Paschke, A. 2001. Stability of food allergens and allergenicity of processed foods. J Chromatogr B 756:207–228.
13. Boyano Martínez, T., García-Ara, C., Díaz-Pena, J.M., Muñoz, F.M., García Sánchez, G., Esteban, M.M. 2001. Validity of specific IgE antibodies in children with egg allergy. Clin Exp Allergy 31:1464–1469.
14. Canfield, R. 1963. The amino acid sequence of egg white lysozyme. J Biol Chem 238:2698–2707.
15. Carraro Alleoni, A.C. 2006. Albumen protein and functional properties of gelation and foaming. Sci Agric (Piracicaba, Braz.) 63(3):291–298.
16. Cooke, S.K., Sampson, H.A. 1997. Allergenic properties of ovomucoid in man. J Immunol 159:2026–2032.
17. Donovan, J.W., Davis, J.G., White, L.M. 1970. Chemical and physical characterization of ovomucin, a sulfated glycoprotein complex from chicken eggs. Biochim Biophys Acta 207:190–201.
18. Ebbehoj, K., Dahl, A.M., Frokiaer, H., Norgaard, A., Poulsen, L.K., Barkholt, V. 1995. Purification of egg-white allergens. Allergy 50:133–141.
19. Eigenmann, P.A. 2000. Anaphylactic reactions to raw eggs after negative challenges with cooked eggs. J Allergy Clin Immunol 105:587–588.
20. Elsayed, S., Stavseng, L. 1994. Epitope mapping of region 11–70 of ovalbumin (Gal d I) using five synthetic peptides. Int Arch Allergy Immunol 104:65–71.
21. Gremel, S., Paschke, A. 2007. Reducing allergens in egg and egg products. In Managing Allergens in Food, eds. C. Mills, H. Wichers, K. Hoffmann-Sommergruber, Woodhead Publishing, Ablington, Cambridge, U.K., pp. 178–186.
22. Hobson, D.J., Rupa, P., Diaz, G.J., Zhang, H., Yang, M., Mine, Y., Turner, P.V., Kirby, G.M. 2007. Proteomic analysis of ovomucoid hypersensitivity in mice by two-dimensional difference gel electrophoresis (2D-DIGE). Food Chem Toxicol 45:2372–2380.
23. Hoffman, D.R. 1983. Immunochemical identification of the allergens in egg white. J Allergy Clin Immunol 71:481–486.
24. Hofmeister, F. 1890. Über die Darstellung von krystallisiertem Eieralbumin. Zeitschr Physiol Chem 14:165–174.
25. Holen, E., Elsayed, S. 1990. Characterization of four major allergens of hen-egg white by IEF/- SDS-PAGE combined with electrophoretic transfer and IgE-immunoautoradiography. Int Arch Allergy Immunol 91:136–141.
26. Holen, E., Bolann, B., Elsayed, S. 2001. Novel B and T cell epitopes of chicken ovomucoid (Gal d 1) induce T cell secretion of IL-6, IL-13, and IFN-gamma. Clin Exp Allergy 31:952–964.
27. Huntington, J.A., Stein, P.E. 2001. Structure and properties of ovalbumin. J Chromatogr B 756:189–198.
28. InformAll Database. 2008. Communicating about food allergies. Available at: http://www.foodallergens.ifr.ac.uk.
29. Järvinen, K.M., Beyer, K., Vila, L., Bardina, L., Mishoe, M., Sampson, H.A. 2007. Specificity of IgE antibodies to sequential epitopes of hen’s egg ovomucoid as a marker for persistence of egg allergy. Allergy 62:758–765.
30. Kahlert, H., Petersen, A., Becker, W.M., Schlaak, M. 1992. Epitope analysis of the allergen ovalbumin (Gal d II) with monoclonal antibodies and patients’ IgE. Mol Immunol 29:1191–1201.
31. Kato, I., Schrode, J., Kohr, W.J., Lakowski, M. Jr. 1987. Chicken ovomucoid: Determination of its amino acid sequence, determination of the trypsin reactive site, and preparation of all three of its domains. Biochemistry 26:193–201.
32. Kato, Y., Oozawa, E., Matsuda, T. 2001. Decrease in antigenic and allergenic potentials of ovomucoid by heating in the presence of wheat flour: Dependence on wheat variety and intermolecular disulfide bridges. J Agric Food Chem 49:3661–3665.
33. Langeland, T. 1982a. A clinical and immunological study of allergy to hen’s egg white. II. Antigens in hen’s egg white studied by crossed immunoelectrophoresis (CIE). Allergy 37:323–333.
34. Langeland, T. 1982b. A clinical and immunological study of allergy to hen’s egg white. III. Allergens in hen’s egg white studied by crossed radio-immunoelectrophoresis (CRIE). Allergy 37:521–530.
35. Leduc, V., Demeulemester, C., Polack, B., Guizard, C., Le-Guern, L., Peltre, G. 1999. Immunochemical detection of egg-white antigens and allergens in meat products. Allergy 54:464–472.
36. Mine, Y., Rupa, P. 2004. Immunological and biochemical properties of egg allergens. Worlds Poult Sci J 60:321–330.
37. Mine, Y., Zhang, J.W. 2002a. Identification and fine mapping of IgG and IgE epitopes in ovomucoid. Biochem Biophys Res Commun 292:1070–1074.
38. Mine, Y., Zhang, J.W. 2002b. Comparative studies on antigenicity and allergenicity of native and denatured egg white proteins. J Agric Food Chem 50:2679–2683.
39. Mine, Y., Sasaki, E., Zhang, J.W. 2003. Reduction of antigenicity and allergenicity of genetically modified egg white allergen, ovomucoid third domain. Biochem Biophys Res Commun 302:133–137.
40. NDA Opinions. 2004. Opinion of the scientific panel on dietetic products, nutrition and allergies on a request from the commission relating to the evaluation of allergenic foods for labelling purposes (Request No. EFSA-Q-2003-016). EFSA J 32:1–197.
41. Perlmann, G.E. 1952. Enzymatic dephosphorylation of ovalbumin and plakalbumin. J Gen Physiol 35:711–726.
42. Petersen, S.B., Jonson, V., Fojan, P., Wimmer, R., Pedersen, S. 2004. Sorbitol prevents the selfaggregation of unfolded lysozyme leading to and up to 13 degrees C stabilisation of the folded form. J Biotechnol 114:269–278.
43. Poulsen, L.K., Hansen, T.K., Noregaard, A., Verstergaard, H., Stahl Skov, P., Bindslev-Jensen, C. 2001. Allergens from fish and egg. Allergy 56(s67):39–42.
44. Proctor, V.A., Cunningham, F.E. 1988. The chemistry of lysozyme and its use as a food preservative and a pharmaceutical. CRC Crit Rev Food Sci Nutr 26:359–395.
45. Quirce, S., Diez-Gomez, M.L., Eiras, P., Cuevas, M., Baz, G., Losada, E. 1998. Inhalant allergy to egg yolk and egg white proteins. Clin Exp Allergy 28:478–485.
46. Rupa, P., Hamilton, K., Cirinna, M., Wilkie, B.N. 2007. A neonatal swine model of allergy induced by the major food allergen chicken ovomucoid (Gal d 1). Int Arch Allergy Immunol 146:11–18.
47. Sakai, K., Matsuoka, A., Ushiyama, Y., Shimoda, T., Ueda, N. 1998. Appearance of ovomucoid in coagulated egg yolk passing through from soluble fraction of coagulated egg white in boiled egg. Arerugi 47:1176–1181.
48. Sampson, H.A., Cooke, S. 1992. The antigenicity and allergenicity of microparticulated proteins: Simplesse®. Clin Exp Allergy 22:963–969.
49. Sava, G. 1996. Pharmacological aspects and therapeutic applications of lysozymes. EXS 75:433–449.
50. Shimojo, N., Katsuki, T., Coligan, J.E., Nishimura, Y., Sasazuki, T., Tsunoo, H., Sakamaki, T., Kohno, Y., Niimi, H. 1994. Identification of the disease-related T cell epitope of ovalbumin and epitope-targeted T cell inactivation in egg allergy. Int Arch Allergy Immunol 105:155–161.
51. So, T., Ito, H.O., Koga, T., Watanabe, S., Ueda, T., Imoto, T. 1997. Depression of T-cell epitope generation by stabilizing hen lysozyme. J Biol Chem 272:32136–32140.
52. So, T., Ito, H., Hirata, M., Ueda, T., Imoto, T. 2001. Contribution of conformational stability of hen lysozyme to induction of type 2 T-helper immune responses. Immunology 104:259–268.
53. Szepfalusi, Z., Ebner, C., Pandjaitan, R., Orlicek, F., Scheiner, O., Boltz-Nitulescu, G., Kraft, D., Ebner, H. 1994. Egg yolk alpha-livetin (chicken serum albumin) is a cross-reactive allergen in the bird-egg syndrome. J Allergy Clin Immunol 93:932–942.
54. Urisu, A., Ando, H., Morita, Y., Wada, E., Yasaki, T., Yamada, K., Komada, K., Torii, S., Goto, M., Wakamatsu, T. 1997. Allergenic activity of heated and ovomucoid-depleted egg white. J Allergy Clin Immunol 100:171–176.
55. van Toorenenbergen, A.W., Huijskesheins, M.I.E., Van Wijk, R.G. 1994. Different pattern of IgE binding to chicken egg yolk between patients with inhalant allergy to birds and food-allergic children. Int Arch Allergy Immunol 104:199–203.
56. Walsh, B.J., Barnett, D., Burley, R.W., Elliott, C., Hill, D.J., Howden, M.E.H. 1988. New allergens from hen’s egg white and egg yolk. In vitro study of ovomucin, apovitellenin I and VI, and phosvitin. Int Arch Allergy Immunol 87:81–86.
57. Walsh, B.J., Hill, D.J., Macoun, P., Cairns, D., Howden, M.E.H. 2005. Detection of four distinct groups of hen egg allergens binding IgE in the sera of children with egg allergy. Allergol Immunopathol 33(4):183–191.
58. Williams, J. 1962. Serum proteins and the livetins in hen’s-egg yolk. Biochem J 83:346–355.
59. Williams, J., Elleman, T.C., Kingston, I.B., Wilkins, A.G., Kuhn, K.A. 1982. The primary structure of hen ovotransferrin. Eur J Biochem 122:275–278.
60. Zhang, J.W., Mine, Y. 1998. Characterization of IgE and IgG epitopes on ovomucoid using egg-white-allergic patients’ sera. Biochem Biophys Res Commun 253:124–127.