Intrinsic determinants of Aβ 12-24 pH-dependent self-assembly revealed by combined computational and experimental studies

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Xu, Weixin ^a,b   Zhang, Ce ^c   Derreumaux, Philippe ^d   Gräslund, Astrid ^e   Morozova Roche, Ludmilla ^c   Mu, Yuguang ^b  

^a EAST CHINA NORMAL UNIVERSITY   (China)

^b NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^c UMEÅ UNIVERSITY   (Sweden)

^d INST DE BIOLOGIE PHYSICO CHIMIQUE   (France)

^e STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[12-24]; UNCLASSIFIED DRUG; WATER;

AMYLOIDOSIS; ARTICLE; ATOMIC FORCE MICROSCOPY; BETA SHEET; CONTROLLED STUDY; DIMERIZATION; ENERGY; EXPERIMENTAL STUDY; FLUORESCENCE; HYDRATION; HYDROPHOBICITY; MATHEMATICAL ANALYSIS; MOLECULAR RECOGNITION; PH; PROBABILITY; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; SOLVATION; STATIC ELECTRICITY; AMINO ACID SEQUENCE; CHEMICAL PHENOMENA; CHEMISTRY; HYDROGEN BOND; KINETICS; METABOLISM; MOLECULAR DYNAMICS; PROTEIN MULTIMERIZATION; THERMODYNAMICS;

AMINO ACID SEQUENCE; AMYLOID BETA-PEPTIDES; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MICROSCOPY, ATOMIC FORCE; MOLECULAR DYNAMICS SIMULATION; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; THERMODYNAMICS; WATER;

EID: 80053045958     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024329     Document Type: Article

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