Cyclosporin A inhibits nucleotide excision repair via downregulation of the xeroderma pigmentosum group A and G proteins, which is mediated by calcineurin inhibition

Experimental Dermatology

Volumn 20, Issue 10, 2011, Pages 795-799

  Kuschal, Christiane ^a   Thoms, Kai Martin ^a   Boeckmann, Lars ^a   Laspe, Petra ^a   Apel, Antje ^a   Schön, Michael P ^a   Emmert, Steffen ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Calcineurin; Cyclosporin A; Nucleotide excision repair; UV induced skin cancer; Xeroderma pigmentosum

Indexed keywords

CALCINEURIN; CYCLOSPORIN A; NUCLEIC ACID BINDING PROTEIN; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP A PROTEIN; XERODERMA PIGMENTOSUM GROUP G PROTEIN;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EXCISION REPAIR; FIBROBLAST; GENE; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; RNA INTERFERENCE; WESTERN BLOTTING; XERODERMA PIGMENTOSUM;

CALCINEURIN; CELL LINE; CYCLOSPORINE; DNA REPAIR; DNA-BINDING PROTEINS; DOWN-REGULATION; ENDONUCLEASES; FIBROBLASTS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; NUCLEAR PROTEINS; RNA INTERFERENCE; RNA, MESSENGER; SKIN NEOPLASMS; TRANSCRIPTION FACTORS; TRANSPLANTS; XERODERMA PIGMENTOSUM; XERODERMA PIGMENTOSUM GROUP A PROTEIN;

EID: 80052965032     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2011.01320.x     Document Type: Article

References (42)

1. de Fijter J W. Nephrol Dial Transplant 2007: 22 (Suppl 1): i23-i26.
2. Buell J F, Gross T G, Woodle E S. Transplantation 2005: 80: S254-S264.
3. DiGiovanna J J. Transplant Proc 1998: 30: 2771-2775.
4. Tjon A S, Sint N J, Kwekkeboom J et al. Liver Transpl 2010: 16: 837-846.
5. Wimmer C D, Rentsch M, Crispin A et al. Kidney Int 2007: 71: 1271-1278.
6. Hojo M, Morimoto T, Maluccio M et al. Nature 1999: 397: 530-534.
7. Euvrard S, Ulrich C, Lefrancois N. Dermatol Surg 2004: 30: 628-633.
8. Flanagan W M, Corthesy B, Bram R J et al. Nature 1991: 352: 803-807.
9. Zhang Y, Baumgrass R, Schutkowski M et al. Chembiochem 2004: 5: 1006-1009.
10. Oetjen E, Thoms K M, Laufer Y et al. Br J Pharmacol 2005: 144: 982-993.
11. Yarosh D B, Pena A V, Nay S L et al. J Invest Dermatol 2005: 125: 1020-1025.
12. Herman M, Ori Y, Chagnac A et al. J Lab Clin Med 2002: 140: 255-262.
13. Ori Y, Herman M, Chagnac A et al. Biochem Biophys Res Commun 2005: 336: 842-846.
14. Sugie N, Fujii N, Danno K. Photodermatol Photoimmunol Photomed 2002: 18: 163-168.
15. Thoms K M, Kuschal C, Oetjen E et al. Exp Dermatol 2011: 20: 232-236.
16. Kraemer K H, Lee M M, Scotto J. Arch Dermatol 1987: 123: 241-250.
17. Bootsma D, Kraemer K H, Cleaver J E et al. In: Vogelstein B, Kinzler K W, eds. The Genetic Basis of Human Cancer. New York: McGraw-Hill, 2002: 211-237.
18. Emmert S. In: Allgayer H, Rehder H, Fulda S, eds. Hereditary Tumors. From Genes to Clinical Consequences. Weinheim: Wiley-VCH, 2009: 421-439.
19. Fousteri M, Mullenders L H. Cell Res 2008: 18: 73-84.
20. Coin F, Oksenych V, Mocquet V et al. Mol Cell 2008: 31: 9-20.
21. Stigger E, Drissi R, Lee S H. J Biol Chem 1998: 273: 9337-9343.
22. Qiao Y, Spitz M R, Guo Z et al. Mutat Res 2002: 509: 165-174.
23. Thoms K M, Baesecke J, Emmert B et al. Scand J Clin Lab Invest 2007: 67: 580-588.
24. Emmert S, Slor H, Busch D B et al. J Invest Dermatol 2002: 118: 972-982.
25. Khan S G, Muniz-Medina V, Shahlavi T et al. Nucleic Acids Res 2002: 30: 3624-3631.
26. Levy D D, Saijo M, Tanaka K et al. Carcinogenesis 1995: 16: 1557-1563.
27. Thoms K M, Kuschal C, Emmert S. Exp Dermatol 2007: 16: 532-544.
28. Dantal J, Hourmant M, Cantarovich D et al. Lancet 1998: 351: 623-628.
29. Schwaninger M, Blume R, Oetjen E et al. J Biol Chem 1993: 268: 23111-23115.
30. Schwaninger M, Blume R, Kruger M et al. J Biol Chem 1995: 270: 8860-8866.
31. Schwaninger M, Blume R, Oetjen E et al. Naunyn Schmiedebergs Arch Pharmacol 1993: 348: 541-545.
32. Oetjen E, Grapentin D, Blume R et al. Naunyn Schmiedebergs Arch Pharmacol 2003: 367: 227-236.
33. Kruger M, Schwaninger M, Blume R et al. Naunyn Schmiedebergs Arch Pharmacol 1997: 356: 433-440.
34. Mi J, Bolesta E, Brautigan D L et al. Mol Cancer Ther 2009: 8: 135-140.
35. Coin F, Auriol J, Tapias A et al. EMBO J 2004: 23: 4835-4846.
36. Wu X, Shell S M, Yang Z et al. Cancer Res 2006: 66: 2997-3005.
37. Bartels C L, Lambert M W. Biochem Biophys Res Commun 2007: 356: 219-225.
38. Miura N, Miyamoto I, Asahina H et al. J Biol Chem 1991: 266: 19786-19789.
39. Iakoucheva L M, Kimzey A L, Masselon C D et al. Protein Sci 2001: 10: 1353-1362.
40. Yang Z G, Liu Y, Mao L Y et al. Biochemistry 2002: 41: 13012-13020.
41. Bito T, Sumita N, Masaki T et al. Exp Dermatol 2010: 19: 654-660.
42. van Kesteren P C E, Beems R B, Luijten M et al. Carcinogenesis 2009: 30: 538-543.