-
1
-
-
0033014304
-
MS and leukemia: From basic mechanisms to gene-directed therapy
-
Beaupre DM, Kurzrock R. MS and leukemia: from basic mechanisms to gene-directed therapy. J Clin Oncol. 1999;17:1071-1079.
-
(1999)
J Clin Oncol
, vol.17
, pp. 1071-1079
-
-
Beaupre, D.M.1
Kurzrock, R.2
-
2
-
-
0031937682
-
The molecular pathophysiology of myeloid leukaemias: Ras revisited
-
Byrne JL, Marshall CJ. The molecular pathophysiology of myeloid leukaemias: ras revisited. Br J Haematol. 1998;100:256-264.
-
(1998)
Br J Haematol
, vol.100
, pp. 256-264
-
-
Byrne, J.L.1
Marshall, C.J.2
-
3
-
-
0025711758
-
Ras proteins. Some signal developments
-
Bourne HR, Wrischnik L, Kenyon C. Ras proteins. Some signal developments. Nature. 1990;348:678-679.
-
(1990)
Nature
, vol.348
, pp. 678-679
-
-
Bourne, H.R.1
Wrischnik, L.2
Kenyon, C.3
-
4
-
-
0025078512
-
The cellular functions of small GTP-binding proteins
-
Hall A. The cellular functions of small GTP-binding proteins. Science. 1990;249:635-640.
-
(1990)
Science
, vol.249
, pp. 635-640
-
-
Hall, A.1
-
5
-
-
0026316096
-
Growth factors and cancer
-
Aaronson SA. Growth factors and cancer. Science. 1991;254:1146-1153.
-
(1991)
Science
, vol.254
, pp. 1146-1153
-
-
Aaronson, S.A.1
-
6
-
-
0023880245
-
Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes
-
Farr CJ, Saiki RK, Erlich HA, McCormick F, Marshall CJ. Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes. Proc Natl Acad Sci USA. 1988;85:1629-1633.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 1629-1633
-
-
Farr, C.J.1
Saiki, R.K.2
Erlich, H.A.3
McCormick, F.4
Marshall, C.J.5
-
7
-
-
0024990090
-
N-ras mutations in adult de novo acute myelogenous leukemia: Prevalence and clinical significance
-
Radich JP, Kopecky KJ, Willman CL, et al. N-ras mutations in adult de novo acute myelogenous leukemia: prevalence and clinical significance. Blood. 1990;76:801-807.
-
(1990)
Blood
, vol.76
, pp. 801-807
-
-
Radich, J.P.1
Kopecky, K.J.2
Willman, C.L.3
-
8
-
-
0026578668
-
Multiple point mutation of N-ras and K-ras oncogenes in myelodysplastic syndrome and acute myelogenous leukemia
-
Nakagawa T, Saitoh S, Imoto S, et al. Multiple point mutation of N-ras and K-ras oncogenes in myelodysplastic syndrome and acute myelogenous leukemia. Oncology. 1992;49:114-122.
-
(1992)
Oncology
, vol.49
, pp. 114-122
-
-
Nakagawa, T.1
Saitoh, S.2
Imoto, S.3
-
9
-
-
0028214608
-
Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia
-
Neubauer A, Dodge RK, George SL, et al. Prognostic importance of mutations in the ras proto-oncogenes in de novo acute myeloid leukemia. Blood. 1994;83:1603-1611.
-
(1994)
Blood
, vol.83
, pp. 1603-1611
-
-
Neubauer, A.1
Dodge, R.K.2
George, S.L.3
-
10
-
-
0028114788
-
The incidence and prognostic significance of mutations in codon 13 of the N-ras gene in acute myeloid leukemia
-
Coghlan DW, Morley AA, Matthews JP, Bishop JF. The incidence and prognostic significance of mutations in codon 13 of the N-ras gene in acute myeloid leukemia. Leukemia. 1994;8:1682-1687.
-
(1994)
Leukemia
, vol.8
, pp. 1682-1687
-
-
Coghlan, D.W.1
Morley, A.A.2
Matthews, J.P.3
Bishop, J.F.4
-
11
-
-
0035127543
-
Mutations in ras proto-oncogenes are associated with lower mdr1 gene expression in adult acute myeloid leukaemia
-
Schaich M, Ritter M, Illmer T, et al. Mutations in ras proto-oncogenes are associated with lower mdr1 gene expression in adult acute myeloid leukaemia. Br J Haematol. 2001;112:300-307.
-
(2001)
Br J Haematol
, vol.112
, pp. 300-307
-
-
Schaich, M.1
Ritter, M.2
Illmer, T.3
-
12
-
-
0024520075
-
Acute myeloid leukemia: Analysis of ras gene mutations and clonality defined by polymorphic X-linked loci
-
Bartram CR, Ludwig WD, Hiddemann W, et al. Acute myeloid leukemia: analysis of ras gene mutations and clonality defined by polymorphic X-linked loci. Leukemia. 1989;3:247-256.
-
(1989)
Leukemia
, vol.3
, pp. 247-256
-
-
Bartram, C.R.1
Ludwig, W.D.2
Hiddemann, W.3
-
13
-
-
0026578223
-
Prevalence of N-ras mutations in children with myelodysplastic syndromes and acute myeloid leukemia
-
Lübbert M, Mirro J Jr., Kitchingman G, et al. Prevalence of N-ras mutations in children with myelodysplastic syndromes and acute myeloid leukemia. Oncogene. 1992;7:263-268.
-
(1992)
Oncogene
, vol.7
, pp. 263-268
-
-
Lübbert, M.1
Mirro Jr., J.2
Kitchingman, G.3
-
14
-
-
0024994577
-
RAS gene mutations in childhood acute myeloid leukemia: A Pediatric Oncology Group study
-
Vogelstein B, Civin CI, Preisinger AC, et al. RAS gene mutations in childhood acute myeloid leukemia: a Pediatric Oncology Group study. Genes Chromosomes Cancer. 1990;2:159-162.
-
(1990)
Genes Chromosomes Cancer
, vol.2
, pp. 159-162
-
-
Vogelstein, B.1
Civin, C.I.2
Preisinger, A.C.3
-
15
-
-
0025254225
-
N-ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis
-
Lübbert M, Mirro J, Miller CW, et al. N-ras gene point mutations in childhood acute lymphocytic leukemia correlate with a poor prognosis. Blood. 1990;75:1163-1169.
-
(1990)
Blood
, vol.75
, pp. 1163-1169
-
-
Lübbert, M.1
Mirro, J.2
Miller, C.W.3
-
16
-
-
0031870590
-
Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: A study of 125 Japanese pediatric cases
-
Yokota S, Nakao M, Horiike S, et al. Mutational analysis of the N-ras gene in acute lymphoblastic leukemia: a study of 125 Japanese pediatric cases. Int J Hematol. 1998;67:379-387.
-
(1998)
Int J Hematol
, vol.67
, pp. 379-387
-
-
Yokota, S.1
Nakao, M.2
Horiike, S.3
-
17
-
-
20144374673
-
RAS mutation is associated with hyperdiploidy and parental characteristics in pediatric acute lymphoblastic leukemia
-
Wiemels JL, Zhang Y, Chang J, et al. RAS mutation is associated with hyperdiploidy and parental characteristics in pediatric acute lymphoblastic leukemia. Leukemia. 2005;19:415-419.
-
(2005)
Leukemia
, vol.19
, pp. 415-419
-
-
Wiemels, J.L.1
Zhang, Y.2
Chang, J.3
-
18
-
-
13544268759
-
RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia
-
Perentesis JP, Bhatia S, Boyle E, et al. RAS oncogene mutations and outcome of therapy for childhood acute lymphoblastic leukemia. Leukemia. 2004;18:685-692.
-
(2004)
Leukemia
, vol.18
, pp. 685-692
-
-
Perentesis, J.P.1
Bhatia, S.2
Boyle, E.3
-
19
-
-
0036720398
-
The roles of FLT3 in hematopoiesis and leukemia
-
Gilliland DG, Griffin JD. The roles of FLT3 in hematopoiesis and leukemia. Blood. 2002;100:1532-1542.
-
(2002)
Blood
, vol.100
, pp. 1532-1542
-
-
Gilliland, D.G.1
Griffin, J.D.2
-
20
-
-
16844380787
-
Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis
-
Ono R, Nakajima H, Ozaki K, et al. Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis. J Clin Invest. 2005;115:919-929.
-
(2005)
J Clin Invest
, vol.115
, pp. 919-929
-
-
Ono, R.1
Nakajima, H.2
Ozaki, K.3
-
21
-
-
0031881426
-
RAS mutations in pediatric leukemias with MLL gene rearrangements
-
Mahgoub N, Parker RI, Hosler MR, et al. RAS mutations in pediatric leukemias with MLL gene rearrangements. Genes Chromosomes Caracer. 1998;21:270-275.
-
(1998)
Genes Chromosomes Caracer
, vol.21
, pp. 270-275
-
-
Mahgoub, N.1
Parker, R.I.2
Hosler, M.R.3
-
22
-
-
0022135739
-
Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group
-
Bennett JM, Catovsky D, Daniel MT, et al. Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group. Ann Intern Med. 1985;103:620-625.
-
(1985)
Ann Intern Med
, vol.103
, pp. 620-625
-
-
Bennett, J.M.1
Catovsky, D.2
Daniel, M.T.3
-
23
-
-
0021971421
-
Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7). A report of the French-American-British Cooperative Group
-
Bennett JM, Catovsky D, Daniel MT, et al. Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7). A report of the French-American-British Cooperative Group. Ann Intern Med. 1985;103:460-462.
-
(1985)
Ann Intern Med
, vol.103
, pp. 460-462
-
-
Bennett, J.M.1
Catovsky, D.2
Daniel, M.T.3
-
24
-
-
0026725060
-
Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-MO)
-
Bennett JM, Catovsky D, Daniel MT, et al. Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-MO). Br J Haematol. 1992;81:458-459.
-
(1992)
Br J Haematol
, vol.81
, pp. 458-459
-
-
Bennett, J.M.1
Catovsky, D.2
Daniel, M.T.3
-
25
-
-
0035180774
-
Molecular analysis of fusion transcripts in childhood acute myeloid leukemia in Taiwan
-
Liang DC, Shih LY, Yang CP, Hung IJ, Chen SH, Liu HC. Molecular analysis of fusion transcripts in childhood acute myeloid leukemia in Taiwan. Med Pediatr Oncol. 2001;37:555-556.
-
(2001)
Med Pediatr Oncol
, vol.37
, pp. 555-556
-
-
Liang, D.C.1
Shih, L.Y.2
Yang, C.P.3
Hung, I.J.4
Chen, S.H.5
Liu, H.C.6
-
26
-
-
0036100793
-
Multiplex RT-PCR assay for the detection of major fusion transcripts in Taiwanese children with B-lineage acute lymphoblastic leukemia
-
Liang DC, Shih LY, Yang CP, et al. Multiplex RT-PCR assay for the detection of major fusion transcripts in Taiwanese children with B-lineage acute lymphoblastic leukemia. Med Pediatr Oncol. 2002;39:12-17.
-
(2002)
Med Pediatr Oncol
, vol.39
, pp. 12-17
-
-
Liang, D.C.1
Shih, L.Y.2
Yang, C.P.3
-
27
-
-
0036786289
-
Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: A comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse
-
Shih LY, Huang CF, Wu JH, et al. Internal tandem duplication of FLT3 in relapsed acute myeloid leukemia: a comparative analysis of bone marrow samples from 108 adult patients at diagnosis and relapse. Blood. 2002;100:2387-2392.
-
(2002)
Blood
, vol.100
, pp. 2387-2392
-
-
Shih, L.Y.1
Huang, C.F.2
Wu, J.H.3
-
28
-
-
0027279628
-
Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations
-
Thirman MJ, Gill HJ, Burnett RC, et al. Rearrangement of the MLL gene in acute lymphoblastic and acute myeloid leukemias with 11q23 chromosomal translocations. N Engl J Med. 1993;329:909-914.
-
(1993)
N Engl J Med
, vol.329
, pp. 909-914
-
-
Thirman, M.J.1
Gill, H.J.2
Burnett, R.C.3
-
29
-
-
0141889928
-
Molecular analysis of t(X;11)(q24;q23) in an infant with AML-M4
-
Fu JF, Liang DC, Yang CP, Hsu JJ, Shih LY. Molecular analysis of t(X;11)(q24;q23) in an infant with AML-M4. Genes Chromosomes Cancer. 2003;38:253-259.
-
(2003)
Genes Chromosomes Cancer
, vol.38
, pp. 253-259
-
-
Fu, J.F.1
Liang, D.C.2
Yang, C.P.3
Hsu, J.J.4
Shih, L.Y.5
-
30
-
-
0030003918
-
Molecular analysis of t(11;19) breakpoints in childhood acute leukemias
-
Rubnitz JE, Behm FG, Curcio-Brint AM, et al. Molecular analysis of t(11;19) breakpoints in childhood acute leukemias. Blood. 1996;87:4804-4808.
-
(1996)
Blood
, vol.87
, pp. 4804-4808
-
-
Rubnitz, J.E.1
Behm, F.G.2
Curcio-Brint, A.M.3
-
31
-
-
0028938999
-
Detection of four different 11q23 chromosomal abnormalities by multiplex-PCR and fluorescence-based automatic DNA-fragment analysis
-
Repp R, Borkhardt A, Haupt E, et al. Detection of four different 11q23 chromosomal abnormalities by multiplex-PCR and fluorescence-based automatic DNA-fragment analysis. Leukemia. 1995;9:210-215.
-
(1995)
Leukemia
, vol.9
, pp. 210-215
-
-
Repp, R.1
Borkhardt, A.2
Haupt, E.3
-
32
-
-
13344249756
-
Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11
-
Caligiuri MA, Strout MP, Schichman SA, et al. Partial tandem duplication of ALL1 as a recurrent molecular defect in acute myeloid leukemia with trisomy 11. Cancer Res. 1996;56:1418-1425.
-
(1996)
Cancer Res
, vol.56
, pp. 1418-1425
-
-
Caligiuri, M.A.1
Strout, M.P.2
Schichman, S.A.3
-
33
-
-
12944259142
-
Detection of leukemia-associated MIL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors
-
Megonigal MD, Cheung NK, Rappaport EF, et al. Detection of leukemia-associated MIL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors. Proc Natl Acad Sci USA. 2000;97:2814-2819.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 2814-2819
-
-
Megonigal, M.D.1
Cheung, N.K.2
Rappaport, E.F.3
-
34
-
-
1542503817
-
Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia
-
Shih LY, Huang CF, Wang PN, et al. Acquisition of FLT3 or N-ras mutations is frequently associated with progression of myelodysplastic syndrome to acute myeloid leukemia. Leukemia. 2004;18:466-475.
-
(2004)
Leukemia
, vol.18
, pp. 466-475
-
-
Shih, L.Y.1
Huang, C.F.2
Wang, P.N.3
-
35
-
-
26944447953
-
Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia
-
Goemans BF, Zwaan CM, Miller M, et al. Mutations in KIT and RAS are frequent events in pediatric core-binding factor acute myeloid leukemia. Leukemia. 2005;19:1536-1542.
-
(2005)
Leukemia
, vol.19
, pp. 1536-1542
-
-
Goemans, B.F.1
Zwaan, C.M.2
Miller, M.3
-
36
-
-
23744498520
-
Mutations in the receptor tyrosine kinase pathway are associated with clinical outcome in patients with acute myeloblastic leukemia harboring t(8;21)(q22;q22)
-
Nanri T, Matsuno N, Kawakita T, et al. Mutations in the receptor tyrosine kinase pathway are associated with clinical outcome in patients with acute myeloblastic leukemia harboring t(8;21)(q22;q22). Leukemia. 2005;19:1361-1366.
-
(2005)
Leukemia
, vol.19
, pp. 1361-1366
-
-
Nanri, T.1
Matsuno, N.2
Kawakita, T.3
-
37
-
-
0013312329
-
Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification
-
Armstrong SA, Rung AL, Mabon ME, et al. Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification. Cancer Cell. 2003;3:173-183.
-
(2003)
Cancer Cell
, vol.3
, pp. 173-183
-
-
Armstrong, S.A.1
Rung, A.L.2
Mabon, M.E.3
-
38
-
-
9144244169
-
FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy
-
Taketani T, Taki T, Sugita K, et al. FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy. Blood. 2004;103:1085-1088.
-
(2004)
Blood
, vol.103
, pp. 1085-1088
-
-
Taketani, T.1
Taki, T.2
Sugita, K.3
-
39
-
-
3142620903
-
Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia
-
Tartaglia M, Martinelli S, Cazzaniga G, et al. Genetic evidence for lineage-related and differentiation stage-related contribution of somatic PTPN11 mutations to leukemogenesis in childhood acute leukemia. Blood. 2004;104:307-313.
-
(2004)
Blood
, vol.104
, pp. 307-313
-
-
Tartaglia, M.1
Martinelli, S.2
Cazzaniga, G.3
|