GSK-3β inhibition by lithium confers resistance to chemotherapy-induced apoptosis through the repression of CD95 (Fas/APO-1) expression

Experimental Cell Research

Volumn 300, Issue 2, 2004, Pages 354-364

  Beurel, Eléonore ^a   Kornprobst, Michel ^b   Blivet Van Eggelpoël, Marie José ^a   Ruiz Ruiz, Carmen ^c   Cadoret, Axelle ^a   Capeau, Jacqueline ^a   Desbois Mouthon, Christèle ^a  

^a INSERM   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITY OF GRANADA   (Spain)

Author keywords

Apoptosis; Caspase 8; CD95; Chemotherapy; GSK 3 ; Lithium; p53

Indexed keywords

2 (3 CHLORO 4 HYDROXYANILINO) 3 (2 NITROPHENYL)MALEIMIDE; ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CASPASE 8; ETOPOSIDE; FAS ANTIGEN; GLYCOGEN SYNTHASE KINASE 3; LITHIUM; LUCIFERASE; MUTANT PROTEIN; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN P53; SERINE; UNCLASSIFIED DRUG; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); GLYCOGEN SYNTHASE KINASE 3 BETA;

ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL STRAIN HEPG2; CELL SURFACE; DRUG SENSITIVITY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PLASMID; PRIORITY JOURNAL; REPORTER GENE; SIGNAL TRANSDUCTION; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; PROMOTER REGION;

ANTIGENS, CD95; APOPTOSIS; CAMPTOTHECIN; DNA TOPOISOMERASES, TYPE I; DNA TOPOISOMERASES, TYPE II; ETOPOSIDE; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; LITHIUM; PROMOTER REGIONS (GENETICS); TUMOR SUPPRESSOR PROTEIN P53;

EID: 4744375264     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yexcr.2004.08.001     Document Type: Article

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