PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation

Blood

Volumn 113, Issue 18, 2009, Pages 4370-4380

  Yan, Pengrong ^a,b   Fu, Jing ^a,b   Qu, Zhaoxia ^a,b   Li, Shirong ^a,b   Tanaka, Takashi ^c   Grusby, Michael J ^d   Xiao, Gutian ^a,b  

^a UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c RIKEN Center for Integrative Medical Sciences   (Japan)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; LYSINE; MESSENGER RNA; PDLIM 2 PROTEIN; PROTEASOME; REGULATOR PROTEIN; TAX PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VIRUS PROTEIN; ACTIN BINDING PROTEIN; PDLIM2 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL NUCLEUS MATRIX; CELL TRANSFORMATION; CELLULAR DISTRIBUTION; COLONY FORMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOWN REGULATION; ENZYME DEGRADATION; FEMALE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS INFECTION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LEUKEMOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; SCID MOUSE; SIGNAL TRANSDUCTION; STABLE TRANSFECTION; T CELL LEUKEMIA; T LYMPHOCYTE; UBIQUITINATION; ANIMAL; ANIMAL EMBRYO; CELL NUCLEUS; CLONOGENIC ASSAY; CYTOLOGY; CYTOPLASM; EXPERIMENTAL NEOPLASM; FIBROBLAST; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY; RAT; RETROVIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY; VIRUS CELL TRANSFORMATION;

ANIMALS; CELL NUCLEUS; CELL TRANSFORMATION, VIRAL; COLONY-FORMING UNITS ASSAY; CYTOPLASM; EMBRYO, MAMMALIAN; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, VIRAL; GENE PRODUCTS, TAX; HTLV-I INFECTIONS; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; LUCIFERASES; MICE; MICE, SCID; MICROFILAMENT PROTEINS; NEOPLASMS, EXPERIMENTAL; NUCLEAR MATRIX; PROTEASOME ENDOPEPTIDASE COMPLEX; RATS; RETROVIRIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UBIQUITINATION;

EID: 66149089133     PISSN: 00064971     EISSN: 15280020     Source Type: None    
DOI: 10.1182/blood-2008-10-185660     Document Type: Article

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