Mycobacterial PIMs inhibit host inflammatory responses through CD14-dependent and CD14-independent mechanisms

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Court, Nathalie ^a,b   Rose, Stéphanie ^a,b   Bourigault, Marie Laure ^a,b   Front, Sophie ^a,b   Martin, Olivier R ^c,d   Dowling, Jennifer K ^e   Kenny, Elaine F ^e   O'Neill, Luke ^e   Erard, François ^a,b   Quesniaux, Valerie F J ^a,b  

^a UNIVERSITÉ D'ORLÉANS   (France)

^b CNRS   (France)

^c Université d'Orléans   (France)

^d CNRS UMR6005   (France)

^e TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

1 O ALPHA DEXTRO MANNOPYRANOSYL 2 O PHOSPHATIDYL DEXTRO MYO INOSITOL; 2 O ALPHA DEXTRO MANNOPYRANOSYL 1 O PHOSPHATIDYL DEXTRO MYO INOSITOL; [1,3 BIS (ALPHA DEXTRO MANNOPYRANOSYL) 2 O PHOSPHATIDYL GLYCEROL]; ANTIINFLAMMATORY AGENT; CD14 ANTIGEN; INTERLEUKIN 12P40; LIPOPOLYSACCHARIDE; MYCOBACTERIUM ANTIGEN; PHOSPHATIDYLINOSITOL; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; INTERLEUKIN 12; MANNOSIDE; PACLITAXEL; SURFACTANT; TOLL LIKE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; ACYLATION; ANIMAL; C57BL MOUSE; CELL STRAIN HEK293; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MYCOBACTERIUM; PATHOLOGY; SECRETION; SOLUBILITY;

CORYNEBACTERINEAE; MURINAE;

ACYLATION; ANIMALS; ANTIGENS, CD14; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLAMMATION; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; MACROPHAGES; MANNOSIDES; MICE; MICE, INBRED C57BL; MYCOBACTERIUM; PACLITAXEL; SIGNAL TRANSDUCTION; SOLUBILITY; SURFACE-ACTIVE AGENTS; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80052861988     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024631     Document Type: Article

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