-
1
-
-
69049110868
-
Leukocyte adhesion deficiency syndrome: A controversy solved
-
Abram CL, Lowell CA (2009) Leukocyte adhesion deficiency syndrome: a controversy solved. Immunol Cell Biol 87:440-2
-
(2009)
Immunol Cell Biol
, vol.87
, pp. 440-442
-
-
Abram, C.L.1
Lowell, C.A.2
-
2
-
-
33749354937
-
The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1
-
DOI 10.1158/1078-0432.CCR-06-0792
-
Barkan B, Starinsky S, Friedman E et al. (2006) The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1. Clin Cancer Res 12:5533-42 (Pubitemid 44497271)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.18
, pp. 5533-5542
-
-
Barkan, B.1
Starinsky, S.2
Friedman, E.3
Stein, R.4
Kloog, Y.5
-
3
-
-
0024521004
-
Contact allergic dermatitis
-
Bergstresser PR (1989) Contact allergic dermatitis. Arch Dermatol 125: 276-9
-
(1989)
Arch Dermatol
, vol.125
, pp. 276-279
-
-
Bergstresser, P.R.1
-
4
-
-
32444441115
-
PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis
-
DOI 10.1016/j.molcel.2006.01.012, PII S1097276506000323
-
Bivona TG, Quatela SE, Bodemann BO et al. (2006) PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis. Mol Cell 21:481-93 (Pubitemid 43228004)
-
(2006)
Molecular Cell
, vol.21
, Issue.4
, pp. 481-493
-
-
Bivona, T.G.1
Quatela, S.E.2
Bodemann, B.O.3
Ahearn, I.M.4
Soskis, M.J.5
Mor, A.6
Miura, J.7
Wiener, H.H.8
Wright, L.9
Saba, S.G.10
Yim, D.11
Fein, A.12
Perez De Castro, I.13
Li, C.14
Thompson, C.B.15
Cox, A.D.16
Philips, M.R.17
-
5
-
-
27744571333
-
Analysis of Ras and Rap activation in living cells using fluorescent Ras binding domains
-
DOI 10.1016/j.ymeth.2005.05.022, PII S1046202305001283, GTPases
-
Bivona TG, Philips MR (2005) Analysis of Ras and Rap activation in living cells using fluorescent Ras binding domains. Methods 37:138-45 (Pubitemid 41587422)
-
(2005)
Methods
, vol.37
, Issue.2
, pp. 138-145
-
-
Bivona, T.G.1
Philips, M.R.2
-
6
-
-
0842266583
-
Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion
-
DOI 10.1083/jcb.200311093
-
Bivona TG, Wiener HH, Ahearn IM et al. (2004) Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. J Cell Biol 164:461-70 (Pubitemid 38174773)
-
(2004)
Journal of Cell Biology
, vol.164
, Issue.3
, pp. 461-470
-
-
Bivona, T.G.1
Wiener, H.H.2
Ahearn, I.M.3
Silletti, J.4
Chiu, V.K.5
Philips, M.R.6
-
7
-
-
1842684988
-
Immune sensitization in the skin is enhanced by antigen-independent effects of IgE
-
DOI 10.1016/S1074-7613(04)00080-9, PII S1074761304000809
-
Bryce PJ, Miller ML, Miyajima I et al. (2004) Immune sensitization in the skin is by antigen-independent effects of IgE. Immunity 20:381-92 (Pubitemid 38482117)
-
(2004)
Immunity
, vol.20
, Issue.4
, pp. 381-392
-
-
Bryce, P.J.1
Miller, M.L.2
Miyajima, I.3
Tsai, M.4
Galli, S.J.5
Oettgen, H.C.6
-
8
-
-
0033756553
-
CD28 and the tyrosine kinase Lck stimulate mitogen activated protein kinase activity in T cells via inhibition of the small G protein Rap1
-
Carey KD, Dillon TJ, Schmitt JM et al. (2000) CD28 and the tyrosine kinase Lck stimulate mitogen activated protein kinase activity in T cells via inhibition of the small G protein Rap1. Mol Cell Biol 20:8409-19
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8409-8419
-
-
Carey, K.D.1
Dillon, T.J.2
Schmitt, J.M.3
-
10
-
-
0021013010
-
Desensitization of contact allergy to DNFB in mice
-
Claman H, Jaffee BD (1983) Desensitization of contact allergy to DNFB in mice. J Immunol 131:2682-6
-
(1983)
J Immunol
, vol.131
, pp. 2682-2686
-
-
Claman, H.1
Jaffee, B.D.2
-
11
-
-
18044405159
-
Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4
-
DOI 10.1128/MCB.25.10.4117-4128.2005
-
Dillon TJ, Carey KD, Wetzel SA et al. (2005) Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4. Mol Cell Biol 25:4117-28 (Pubitemid 40617658)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.10
, pp. 4117-4128
-
-
Dillon, T.J.1
Carey, K.D.2
Wetzel, S.A.3
Parker, D.C.4
Stork, P.J.S.5
-
12
-
-
0032717429
-
Targeting of K-Ras 4B by S-trans, trans-farnesyl thiosalicylic acid
-
Elad G, Paz A, Haklai R et al. (1999) Targeting of K-Ras 4B by S-trans, trans-farnesyl thiosalicylic acid. Biochim Biophys Acta 1452:228-42
-
(1999)
Biochim Biophys Acta
, vol.1452
, pp. 228-242
-
-
Elad, G.1
Paz, A.2
Haklai, R.3
-
13
-
-
1042302752
-
Inhibition of Intimal Thickening in the Rat Carotid Artery Injury Model by a Nontoxic Ras Inhibitor
-
DOI 10.1161/01.ATV.0000112021.98971.f0
-
George J, Sack J, Barshack I et al. (2004) Inhibition of intimal thickening in the rat carotid artery injury model by a nontoxic Ras inhibitor. Arterioscler Thromb Vasc Biol 24:363-8 (Pubitemid 38197591)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.2
, pp. 363-368
-
-
George, J.1
Sack, J.2
Barshack, I.3
Keren, P.4
Goldberg, I.5
Haklai, R.6
Elad-Sfadia, G.7
Kloog, Y.8
Keren, G.9
-
14
-
-
33846205171
-
A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration
-
DOI 10.1158/0008-5472.CAN-06-1878
-
Goldberg L, Kloog Y (2006) A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration. Cancer Res 66:11709-17 (Pubitemid 46094183)
-
(2006)
Cancer Research
, vol.66
, Issue.24
, pp. 11709-11717
-
-
Goldberg, L.1
Kloog, Y.2
-
15
-
-
56249112315
-
Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: A convection-enhanced drug delivery study in rats
-
Goldberg L, Ocherashvilli A, Daniels D et al. (2008) Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats. Mol Cancer Ther 7:3609-16
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3609-3616
-
-
Goldberg, L.1
Ocherashvilli, A.2
Daniels, D.3
-
16
-
-
59449084596
-
New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: Farnesyl-thiosalicylamide inhibits tumor growth in nude mice models
-
Goldberg L, Haklai R, Bauer V et al. (2009) New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesyl-thiosalicylamide inhibits tumor growth in nude mice models. J Med Chem 52:197-205
-
(2009)
J Med Chem
, vol.52
, pp. 197-205
-
-
Goldberg, L.1
Haklai, R.2
Bauer, V.3
-
17
-
-
34848874825
-
Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice
-
DOI 10.1007/s00280-007-0451-6
-
Haklai R, Elad-Sfadia G, Egozi Y et al. (2008) Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice. Cancer Chemother Pharmacol 61:89-96 (Pubitemid 47512630)
-
(2008)
Cancer Chemotherapy and Pharmacology
, vol.61
, Issue.1
, pp. 89-96
-
-
Haklai, R.1
Elad-Sfadia, G.2
Egozi, Y.3
Kloog, Y.4
-
19
-
-
25844440047
-
Inhibition of Ras attenuates the course of experimental autoimmune neuritis
-
DOI 10.1016/j.jneuroim.2005.07.008, PII S0165572805003073
-
Kafri M, Kloog Y, Korczyn AD et al. (2005) Inhibition of Ras attenuates the course of experimental autoimmune neuritis. J Neuroimmunol 168:46-55 (Pubitemid 41398186)
-
(2005)
Journal of Neuroimmunology
, vol.168
, Issue.1-2
, pp. 46-55
-
-
Kafri, M.1
Kloog, Y.2
Korczyn, A.D.3
Ferdman-Aronovich, R.4
Drory, V.5
Katzav, A.6
Wirguin, I.7
Chapman, J.8
-
20
-
-
0035652626
-
Treatment of MRL/lpr mice, a genetic autoimmune model, with the ras inhibitor, farnesylthiosalicylate (FTS)
-
DOI 10.1046/j.1365-2249.2001.01674.x
-
Katzav A, Kloog Y, Korczyn AD et al. (2001) Treatment of MRL/lpr mice, a genetic autoimmune model, with the Ras inhibitor, farnesylthiosalicylate (FTS). Clin Exp Immunol 126:570-7 (Pubitemid 34008734)
-
(2001)
Clinical and Experimental Immunology
, vol.126
, Issue.3
, pp. 570-577
-
-
Katzav, A.1
Kloog, Y.2
Korczyn, A.D.3
Niv, H.4
Karussis, D.M.5
Wang, N.6
Rabinowitz, R.7
Blank, M.8
Shoenfeld, Y.9
Chapman, J.10
-
21
-
-
0028981375
-
Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid
-
Marom M, Haklai R, Ben-Baruch G et al. (1995) Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid. J Biol Chem 270:22263-70
-
(1995)
J Biol Chem
, vol.270
, pp. 22263-22270
-
-
Marom, M.1
Haklai, R.2
Ben-Baruch, G.3
-
22
-
-
34447301486
-
Small GTPases and LFA-1 reciprocally modulate adhesion and signaling
-
DOI 10.1111/j.1600-065X.2007.00538.x
-
Mor A, Dustin ML, Philips MR (2007a) Small GTPases and LFA-1 reciprocally modulate adhesion and signaling. Immunol Rev 218:114-25 (Pubitemid 47052308)
-
(2007)
Immunological Reviews
, vol.218
, Issue.1
, pp. 114-125
-
-
Mor, A.1
Dustin, M.L.2
Philips, M.R.3
-
23
-
-
34447579251
-
The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2
-
DOI 10.1038/ncb1592, PII NCB1592
-
Mor A, Campi G, Du G et al. (2007b) The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospho-lipase D2. Nat Cell Biol 9:713-9 (Pubitemid 47214735)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.6
, pp. 713-719
-
-
Mor, A.1
Campi, G.2
Du, G.3
Zheng, Y.4
Foster, D.A.5
Dustin, M.L.6
Philips, M.R.7
-
24
-
-
67649198206
-
Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane
-
Mor A, Wynne JP, Ahearn IM et al. (2009) Phospholipase D1 regulates lymphocyte adhesion via upregulation of Rap1 at the plasma membrane. Mol Cell Biol 29:3297-306
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3297-3306
-
-
Mor, A.1
Wynne, J.P.2
Ahearn, I.M.3
-
25
-
-
75149197691
-
The Ras antagonist farnesylthiosa-licylic acid ameliorates experimental myocarditis in the rat
-
Pando R, Barshack I, Raz A et al. (2010) The Ras antagonist farnesylthiosa-licylic acid ameliorates experimental myocarditis in the rat. Cardiovasc Pathol 19:94-101
-
(2010)
Cardiovasc Pathol
, vol.19
, pp. 94-101
-
-
Pando, R.1
Barshack, I.2
Raz, A.3
-
26
-
-
64049099833
-
Ras inhibition attenuates myocardial ischemia-reperfusion injury
-
Pando R, Cheporko Y, Haklai R et al. (2009) Ras inhibition attenuates myocardial ischemia-reperfusion injury. Biochem Pharmacol 77: 1593-601
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 1593-1601
-
-
Pando, R.1
Cheporko, Y.2
Haklai, R.3
-
27
-
-
34447312705
-
Signaling by small GTPases in the immune system
-
DOI 10.1111/j.1600-065X.2007.00530.x
-
Scheele JS, Marks RE, Boss GR (2007) Signaling by small GTP in the immune system. Immunol Rev 218:92-101 (Pubitemid 47052300)
-
(2007)
Immunological Reviews
, vol.218
, Issue.1
, pp. 92-101
-
-
Scheele, J.S.1
Marks, R.E.2
Boss, G.R.3
-
28
-
-
35248880520
-
The epidemiology of contact allergy in the general population - Prevalence and main findings
-
DOI 10.1111/j.1600-0536.2007.01220.x
-
Thyssen JP, Linneberg A, Menné T et al. (2007) The epidemiology of contact allergy in the general population-prevalence and main findings. Contact Dermatitis 57:287-99 (Pubitemid 47568789)
-
(2007)
Contact Dermatitis
, vol.57
, Issue.5
, pp. 287-299
-
-
Thyssen, J.P.1
Linneberg, A.2
Menne, T.3
Johansen, J.D.4
-
29
-
-
0013227128
-
A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice
-
DOI 10.1038/sj.onc.1202602
-
Weisz B, Giehl K, Gana-Weisz M et al. (1999) A new functional Ras antagonist inhibits human pancreatic tumor growth in nude mice. Oncogene 18:2579-88 (Pubitemid 29216680)
-
(1999)
Oncogene
, vol.18
, Issue.16
, pp. 2579-2588
-
-
Weisz, B.1
Giehl, K.2
Gana-Weisz, M.3
Egozi, Y.4
Ben-Baruch, G.5
Marciano, D.6
Gierschik, P.7
Kloog, Y.8
-
31
-
-
0020038524
-
Differential inhibition of contact sensitivity by suppressor T cells and suppressor factor induced by combined treatment with dinitrobenzenesulphonate and dinitrofluorobenzene
-
Zimber C, Ben-Efraim S, Weiss DW (1982) Differential inhibition of contact sensitivity by suppressor T cells and suppressor factor induced by combined treatment with dinitrobenzenesulphonate and dinitro-fluorobenzene. Immunology 45:449-57 (Pubitemid 12165609)
-
(1982)
Immunology
, vol.45
, Issue.3
, pp. 449-457
-
-
Zimber, C.1
Ben-Efraim, S.2
Weiss, D.W.3
-
32
-
-
34250726637
-
Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid)
-
DOI 10.1158/1535-7163.MCT-06-0706
-
Zundelevich A, Elad-Sfadia G, Haklai R et al. (2007) Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid). Mol Cancer Ther 6:1765-73 (Pubitemid 46954053)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.6
, pp. 1765-1773
-
-
Zundelevich, A.1
Elad-Sfadia, G.2
Haklai, R.3
Kloog, Y.4
|