Ras inhibition attenuates myocardial ischemia-reperfusion injury

Biochemical Pharmacology

Volumn 77, Issue 10, 2009, Pages 1593-1601

  Pando, Rakefet ^a,b   Cheporko, Yelena ^c   Haklai, Ronit ^b   Maysel Auslender, Sofia ^a   Keren, Gad ^a   George, Jacob ^a   Porat, Eyal ^c   Sagie, Alex ^c   Kloog, Yoel ^b   Hochhauser, Edith ^c  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c RABIN MEDICAL CENTER   (Israel)

Author keywords

C Jun N terminal kinases (JNK); Ischemia reperfusion; Isolated heart; Mammalian sterile 20 like kinase 1 (Mst 1); Ras; S farnesylthiosalicylic acid (FTS)

Indexed keywords

FARNESYLTHIOSALICYLIC ACID; MAMMALIAN STERILE 20 LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE; RAS PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; HEART INFARCTION SIZE; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART MUSCLE PERFUSION; HEART MUSCLE REPERFUSION; HEART PROTECTION; HEART VENTRICLE PERFORMANCE; IN VITRO STUDY; IN VIVO STUDY; ISOLATED HEART; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; THERAPY EFFECT; TREATMENT OUTCOME; TREATMENT RESPONSE; WISTAR RAT;

ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FARNESOL; HEART FUNCTION TESTS; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; RAS PROTEINS; RATS; RATS, INBRED LEW; RATS, WISTAR; SALICYLIC ACIDS;

EID: 64049099833     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.02.010     Document Type: Article

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