Value of immunohistochemical detection of DNA mismatch repair proteins in predicting germline mutation in hereditary colorectal neoplasms

American Journal of Surgical Pathology

Volumn 29, Issue 1, 2005, Pages 96-104

  Shia, Jinru ^a   Klimstra, David S ^a   Nafa, Khedoudja ^a   Offit, Kenneth ^a   Guillem, Jose G ^a   Markowitz, Arnold J ^a   Gerald, William L ^a   Ellis, Nathan A ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Colorectal cancer; Immunohistochemistry; Microsatellite instability

Indexed keywords

DNA; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

ADENOMA; ADULT; AGED; ARTICLE; CANCER SURGERY; COLORECTAL CANCER; COLORECTAL CARCINOMA; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; GENE; GENE MUTATION; GERM LINE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MLH1 GENE; MSH2 GENE; MSH6 GENE; POLYPECTOMY; PROTEIN ANALYSIS;

ADENOCARCINOMA; ADENOMA; ADULT; AGED; BASE PAIR MISMATCH; CARRIER PROTEINS; COLORECTAL NEOPLASMS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; DNA-BINDING PROTEINS; FEMALE; GERM-LINE MUTATION; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MICROSATELLITE REPEATS; MIDDLE AGED; MUTS HOMOLOG 2 PROTEIN; NEOPLASM PROTEINS; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS; TUMOR MARKERS, BIOLOGICAL;

EID: 11144279281     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000146009.85309.3b     Document Type: Article

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