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Volumn 6, Issue 9, 2011, Pages

Iridoid glycosides fraction of folium syringae leaves modulates NF-κB signal pathway and intestinal epithelial cells apoptosis in experimental colitis

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYCLOOXYGENASE 2; DEXTRAN SULFATE; FAS ANTIGEN; FAS LIGAND; FOLIUM SYRINGAE EXTRACT; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 8; IRIDOID; MESSENGER RNA; MYELOPEROXIDASE; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; TRANSCRIPTION FACTOR RELA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; PEROXIDASE;

EID: 80052783370     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024740     Document Type: Article
Times cited : (41)

References (58)
  • 1
  • 2
    • 68049113587 scopus 로고    scopus 로고
    • The evolving epidemiology of inflammatory bowel disease
    • Shanahan F, Bernstein CN, (2009) The evolving epidemiology of inflammatory bowel disease. Curr Opin in Castroenterol 25: 301-305.
    • (2009) Curr Opin in Castroenterol , vol.25 , pp. 301-305
    • Shanahan, F.1    Bernstein, C.N.2
  • 3
    • 33745573362 scopus 로고    scopus 로고
    • Gliotoxin reduces the severity of trinitrobenzene sulfonic acid-induced colitis in mice: evidence of the connection between heme oxygenase-1 and the nuclear factor-κB pathway in vitro and in vivo
    • Jun CD, Kim Y, Choi EY, Kim M, Park B, et al. (2006) Gliotoxin reduces the severity of trinitrobenzene sulfonic acid-induced colitis in mice: evidence of the connection between heme oxygenase-1 and the nuclear factor-κB pathway in vitro and in vivo. Inflamm Bowel Dis 12: 619-629.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 619-629
    • Jun, C.D.1    Kim, Y.2    Choi, E.Y.3    Kim, M.4    Park, B.5
  • 4
    • 33751577977 scopus 로고    scopus 로고
    • Plant sterol guggulsterone inhibits nuclear factor-kappaB signaling in intestinal epithelial cells by blocking IkappaB kinase and ameliorates acute murine colitis
    • Cheon JH, Kim JS, Kim JM, Kim N, Jung HC, et al. (2006) Plant sterol guggulsterone inhibits nuclear factor-kappaB signaling in intestinal epithelial cells by blocking IkappaB kinase and ameliorates acute murine colitis. Inflamm Bowel Dis 12: 1152-1161.
    • (2006) Inflamm Bowel Dis , vol.12 , pp. 1152-1161
    • Cheon, J.H.1    Kim, J.S.2    Kim, J.M.3    Kim, N.4    Jung, H.C.5
  • 5
    • 40049111515 scopus 로고    scopus 로고
    • Treatment of inflammatory bowel disease: a review of medical therapy
    • Kozuch PL, Hanauer SB, (2008) Treatment of inflammatory bowel disease: a review of medical therapy. World J Gastroenterol 14: 354-377.
    • (2008) World J Gastroenterol , vol.14 , pp. 354-377
    • Kozuch, P.L.1    Hanauer, S.B.2
  • 6
    • 59849117799 scopus 로고    scopus 로고
    • Attenuated Apoptosis Response to Fas-ligand in Active Ulcerative Colitis
    • Seidelin JB, Nielsen OH, (2008) Attenuated Apoptosis Response to Fas-ligand in Active Ulcerative Colitis. Inflamm Bowel Dis 14: 1623-1629.
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 1623-1629
    • Seidelin, J.B.1    Nielsen, O.H.2
  • 7
    • 33646572516 scopus 로고    scopus 로고
    • The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model
    • Martin AR, Villegas I, Sanchez-Hidalgo M, de la Lastra CA, (2006) The effects of resveratrol, a phytoalexin derived from red wines, on chronic inflammation induced in an experimentally induced colitis model. Brit J Pharmacol 147: 873-885.
    • (2006) Brit J Pharmacol , vol.147 , pp. 873-885
    • Martin, A.R.1    Villegas, I.2    Sanchez-Hidalgo, M.3    de la Lastra, C.A.4
  • 8
    • 77649337341 scopus 로고    scopus 로고
    • Anti-inflammatory intestinal activity of Abarema cochliacarpos (Gomes) Barneby & Grimes in TNBS colitis model
    • Da Silva MS, Sánchez-Fidalgo S, Talero E, Cárdeno A, da Silva MA, et al. (2010) Anti-inflammatory intestinal activity of Abarema cochliacarpos (Gomes) Barneby & Grimes in TNBS colitis model. J Ethnopharmacol 128: 467-475.
    • (2010) J Ethnopharmacol , vol.128 , pp. 467-475
    • Da Silva, M.S.1    Sánchez-Fidalgo, S.2    Talero, E.3    Cárdeno, A.4    da Silva, M.A.5
  • 9
    • 0036359580 scopus 로고    scopus 로고
    • Cytokines and autoimmunity
    • O'Shea J, Ma A, Lipsky P, (2002) Cytokines and autoimmunity. Nat Rev 2: 37-45.
    • (2002) Nat Rev , vol.2 , pp. 37-45
    • O'Shea, J.1    Ma, A.2    Lipsky, P.3
  • 10
    • 21044454551 scopus 로고    scopus 로고
    • Probiotic therapy in the prevention of pouchitis onset: decreased interleukin-1β, interleukin-8 and interferon-γ gene expression
    • Lammers KM, Vergopoulos A, Babel N, Rizzello F, Morselli C, et al. (2005) Probiotic therapy in the prevention of pouchitis onset: decreased interleukin-1β, interleukin-8 and interferon-γ gene expression. Inflamm Bowel Dis 11: 447-454.
    • (2005) Inflamm Bowel Dis , vol.11 , pp. 447-454
    • Lammers, K.M.1    Vergopoulos, A.2    Babel, N.3    Rizzello, F.4    Morselli, C.5
  • 11
    • 77954651225 scopus 로고    scopus 로고
    • Anti-oxidant effects of resveratrol on mice with DSS-induced ulcerative colitis
    • Yao J, Wang JY, Liu L, Li YX, Xun AY, et al. (2010) Anti-oxidant effects of resveratrol on mice with DSS-induced ulcerative colitis. Arch Med Res 41: 288-294.
    • (2010) Arch Med Res , vol.41 , pp. 288-294
    • Yao, J.1    Wang, J.Y.2    Liu, L.3    Li, Y.X.4    Xun, A.Y.5
  • 12
    • 54049122543 scopus 로고    scopus 로고
    • Acute and chronic responses associated with adrenomedullin administration in experimental colitis
    • Talero E, Sanchez-Fidalgo S, Alarcon de la Lastra C, Illanes M, Calvo JR, et al. (2008) Acute and chronic responses associated with adrenomedullin administration in experimental colitis. Peptides 29: 2001-2012.
    • (2008) Peptides , vol.29 , pp. 2001-2012
    • Talero, E.1    Sanchez-Fidalgo, S.2    Alarcon de la Lastra, C.3    Illanes, M.4    Calvo, J.R.5
  • 13
    • 0037450721 scopus 로고    scopus 로고
    • Apoptosis in chronic inflammatory bowel disease. The importance for pathogenesis and treatment
    • Seidelin JB, Nielsen OH, (2003) Apoptosis in chronic inflammatory bowel disease. The importance for pathogenesis and treatment. Ugeskr Laeger 165: 790-792.
    • (2003) Ugeskr Laeger , vol.165 , pp. 790-792
    • Seidelin, J.B.1    Nielsen, O.H.2
  • 14
    • 0030981633 scopus 로고    scopus 로고
    • CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: a possible role in ulcerative colitis
    • Strater J, Wellisch I, Riedl S, Walczak H, Koretz K, et al. (1997) CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: a possible role in ulcerative colitis. Gastroenterology 113: 160-167.
    • (1997) Gastroenterology , vol.113 , pp. 160-167
    • Strater, J.1    Wellisch, I.2    Riedl, S.3    Walczak, H.4    Koretz, K.5
  • 15
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S, (1997) Apoptosis by death factor. Cell 88: 355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 16
    • 34548612724 scopus 로고    scopus 로고
    • Bacteria- and host-derived mechanisms to control intestinal epithelial cell homeostasis: implications for chronic inflammation
    • Clavel T, Haller D, (2007) Bacteria- and host-derived mechanisms to control intestinal epithelial cell homeostasis: implications for chronic inflammation. Inflamm Bowel Dis 13: 1153-1164.
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1153-1164
    • Clavel, T.1    Haller, D.2
  • 17
    • 0030800070 scopus 로고    scopus 로고
    • Inhibition of death receptor signals by cellular FLIP
    • Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, et al. (1997) Inhibition of death receptor signals by cellular FLIP. Nature 388: 190-195.
    • (1997) Nature , vol.388 , pp. 190-195
    • Irmler, M.1    Thome, M.2    Hahne, M.3    Schneider, P.4    Hofmann, K.5
  • 18
    • 0037331535 scopus 로고    scopus 로고
    • Transforming growth factor-β mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells
    • Beck PL, Rosenberg IM, Xavier RJ, Koh T, Wong JF, et al. (2003) Transforming growth factor-β mediates intestinal healing and susceptibility to injury in vitro and in vivo through epithelial cells. Am J Pathol 162: 597-608.
    • (2003) Am J Pathol , vol.162 , pp. 597-608
    • Beck, P.L.1    Rosenberg, I.M.2    Xavier, R.J.3    Koh, T.4    Wong, J.F.5
  • 20
    • 70350165074 scopus 로고    scopus 로고
    • Plasma transforming growth factor-β1 level in inflammatory bowel disease
    • Kilic ZM, Ayaz S, Özin Y, Nadir I, Cakal B, et al. (2009) Plasma transforming growth factor-β1 level in inflammatory bowel disease. Turk J Gastroenterol 20: 165-170.
    • (2009) Turk J Gastroenterol , vol.20 , pp. 165-170
    • Kilic, Z.M.1    Ayaz, S.2    Özin, Y.3    Nadir, I.4    Cakal, B.5
  • 21
    • 29644441714 scopus 로고    scopus 로고
    • NF-κB and Activator Protein 1 Response Elements and the Role of Histone Modifications in IL-β1-Induced TGF-β1 Gene Transcription
    • Lee KY, Ito K, Hayashi R, Jazrawi EP, Barnes PJ, et al. (2006) NF-κB and Activator Protein 1 Response Elements and the Role of Histone Modifications in IL-β1-Induced TGF-β1 Gene Transcription. J Immunol 176: 603-615.
    • (2006) J Immunol , vol.176 , pp. 603-615
    • Lee, K.Y.1    Ito, K.2    Hayashi, R.3    Jazrawi, E.P.4    Barnes, P.J.5
  • 22
    • 0037447804 scopus 로고    scopus 로고
    • Effect of ulcerative colitis treatment on transforming growth factor β1 in plasma and rectal mucosa
    • Wiercińska-Drapalo A, Flisiak R, Prokopowicz D, (2003) Effect of ulcerative colitis treatment on transforming growth factor β1 in plasma and rectal mucosa. Regul Peptides 113: 57-61.
    • (2003) Regul Peptides , vol.113 , pp. 57-61
    • Wiercińska-Drapalo, A.1    Flisiak, R.2    Prokopowicz, D.3
  • 23
    • 33745853832 scopus 로고    scopus 로고
    • Epithelial cell IκB-Kinase β has an important protective role in clostridium difficile toxin A-induced mucosal injury
    • Chae S, Eckmann L, Miyamoto Y, Pothoulakis C, Karin M, et al. (2006) Epithelial cell IκB-Kinase β has an important protective role in clostridium difficile toxin A-induced mucosal injury. J Immunol 177: 1214-1220.
    • (2006) J Immunol , vol.177 , pp. 1214-1220
    • Chae, S.1    Eckmann, L.2    Miyamoto, Y.3    Pothoulakis, C.4    Karin, M.5
  • 24
    • 77957957868 scopus 로고    scopus 로고
    • Glial-derived neurotrophic factor regulates intestinal epithelial barrier function and inflammation and is therapeutic for murine colitis
    • Zhang DK, He FQ, Li TK, Pang XH, Cui de J, et al. (2010) Glial-derived neurotrophic factor regulates intestinal epithelial barrier function and inflammation and is therapeutic for murine colitis. J Pathol 22: 213-222.
    • (2010) J Pathol , vol.22 , pp. 213-222
    • Zhang, D.K.1    He, F.Q.2    Li, T.K.3    Pang, X.H.4    de Cui, J.5
  • 25
    • 0031781603 scopus 로고    scopus 로고
    • Inflammatory bowel disease: etiology and pathogenesis
    • Fiocchi C, (1998) Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 115: 182-205.
    • (1998) Gastroenterology , vol.115 , pp. 182-205
    • Fiocchi, C.1
  • 26
    • 0029836444 scopus 로고    scopus 로고
    • Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice
    • Neurath MF, Pettersson S, Meyer zum Büschenfelde KH, Strober W, (1996) Local administration of antisense phosphorothioate oligonucleotides to the p65 subunit of NF-kappa B abrogates established experimental colitis in mice. Nat Med 9: 998-1004.
    • (1996) Nat Med , vol.9 , pp. 998-1004
    • Neurath, M.F.1    Pettersson, S.2    Meyer zum Büschenfelde, K.H.3    Strober, W.4
  • 27
    • 0036234459 scopus 로고    scopus 로고
    • Missing pieces in the NF-κB puzzle
    • Ghosh S, Karin M, (2002) Missing pieces in the NF-κB puzzle. Cell 109: 81-96.
    • (2002) Cell , vol.109 , pp. 81-96
    • Ghosh, S.1    Karin, M.2
  • 28
    • 38849199203 scopus 로고    scopus 로고
    • Shared Principles in NF-κB Signaling
    • Hayden MS, Ghosh S, (2008) Shared Principles in NF-κB Signaling. Cell 132: 344-362.
    • (2008) Cell , vol.132 , pp. 344-362
    • Hayden, M.S.1    Ghosh, S.2
  • 29
    • 33845943499 scopus 로고    scopus 로고
    • Simvastatin inhibits NF-κB signaling in intestinal epithelial cells and ameliorates acute murine colitis
    • Lee JY, Kim JS, Kim JM, Kim N, Jung HC, et al. (2007) Simvastatin inhibits NF-κB signaling in intestinal epithelial cells and ameliorates acute murine colitis. Int Immunopharmacol 7: 241-248.
    • (2007) Int Immunopharmacol , vol.7 , pp. 241-248
    • Lee, J.Y.1    Kim, J.S.2    Kim, J.M.3    Kim, N.4    Jung, H.C.5
  • 31
    • 43549085501 scopus 로고    scopus 로고
    • NF-κB in inflammatory bowel disease
    • Atreya I, Atreya R, Neurath MF, (2008) NF-κB in inflammatory bowel disease. J Intern Med 263: 591-596.
    • (2008) J Intern Med , vol.263 , pp. 591-596
    • Atreya, I.1    Atreya, R.2    Neurath, M.F.3
  • 32
    • 79952210175 scopus 로고    scopus 로고
    • Preparative separation and enrichment of syringopicroside from Folium syringae leaves with macroporous resins
    • accepted 28 November 2010, Article ID 572570, doi:10.1155/2010/572570
    • Liu X, Wang J, Zhou C, Gan L, (2010) Preparative separation and enrichment of syringopicroside from Folium syringae leaves with macroporous resins. J Biomed Biotechnol accepted 28 November 2010, Article ID 572570, doi:10.1155/2010/572570.
    • (2010) J Biomed Biotechnol
    • Liu, X.1    Wang, J.2    Zhou, C.3    Gan, L.4
  • 33
    • 78651380339 scopus 로고    scopus 로고
    • Anti-inflammatory effects of iridoid glycosides fraction of Folium syringae leaves on TNBS-induced colitis in rats
    • Liu X, Wang JM, (2011) Anti-inflammatory effects of iridoid glycosides fraction of Folium syringae leaves on TNBS-induced colitis in rats. J Ethnopharmacol 133: 780-787.
    • (2011) J Ethnopharmacol , vol.133 , pp. 780-787
    • Liu, X.1    Wang, J.M.2
  • 34
    • 0027224059 scopus 로고
    • Clinicopathlolgic study of dextran sulfate sodium experimental murine colitis
    • Cooper HS, Murthy SN, Shah RS, Sedergran DJ, (1993) Clinicopathlolgic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69: 238-249.
    • (1993) Lab Invest , vol.69 , pp. 238-249
    • Cooper, H.S.1    Murthy, S.N.2    Shah, R.S.3    Sedergran, D.J.4
  • 35
    • 0026556835 scopus 로고
    • Exacerbation of experimental colitis by non-steroidal antinflammatory drugs is not related to elevate leukotriene B4 synthesis
    • Wallace JL, Keenan CM, Gale D, Shoupe TS, (1992) Exacerbation of experimental colitis by non-steroidal antinflammatory drugs is not related to elevate leukotriene B4 synthesis. Gastroenterology 102: 18-27.
    • (1992) Gastroenterology , vol.102 , pp. 18-27
    • Wallace, J.L.1    Keenan, C.M.2    Gale, D.3    Shoupe, T.S.4
  • 36
    • 0035834506 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-α synthesis inhibitors on rat trinitrobenzene sulphonic acid-induced chronic colitis
    • Bobin-Dubigeon C, Collin X, Grimaud N, Robert JM, Le Baut G, et al. (2001) Effects of tumor necrosis factor-α synthesis inhibitors on rat trinitrobenzene sulphonic acid-induced chronic colitis. Eur J Pharmacol 421: 103-110.
    • (2001) Eur J Pharmacol , vol.421 , pp. 103-110
    • Bobin-Dubigeon, C.1    Collin, X.2    Grimaud, N.3    Robert, J.M.4    Le Baut, G.5
  • 37
    • 0021742157 scopus 로고
    • Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models
    • Krawisz JE, Sharon P, Stenson WF, (1984) Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 87: 1344-1350.
    • (1984) Gastroenterology , vol.87 , pp. 1344-1350
    • Krawisz, J.E.1    Sharon, P.2    Stenson, W.F.3
  • 38
    • 33749365523 scopus 로고    scopus 로고
    • Melatonin modulates signal transduction pathways and apoptosis in experimental colitis
    • Mazzon E, Esposito E, Crisafulli C, Riccardi L, Muià C, et al. (2006) Melatonin modulates signal transduction pathways and apoptosis in experimental colitis. J Pineal Res 41: 363-373.
    • (2006) J Pineal Res , vol.41 , pp. 363-373
    • Mazzon, E.1    Esposito, E.2    Crisafulli, C.3    Riccardi, L.4    Muià, C.5
  • 39
    • 38949148964 scopus 로고    scopus 로고
    • DA-6034, a derivative of flavonoid, prevents and ameliorates dextran sulfate sodium-induced colitis and inhibits colon carcinogenesis
    • Nam SY, Kim JS, Kim JM, Lee JY, Kim N, et al. (2008) DA-6034, a derivative of flavonoid, prevents and ameliorates dextran sulfate sodium-induced colitis and inhibits colon carcinogenesis. Exp Biol Med (Maywood) 233: 180-191.
    • (2008) Exp Biol Med (Maywood) , vol.233 , pp. 180-191
    • Nam, S.Y.1    Kim, J.S.2    Kim, J.M.3    Lee, J.Y.4    Kim, N.5
  • 40
    • 0031902251 scopus 로고    scopus 로고
    • Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease
    • Singer II, Kawka DW, Schloemann S, Tessner T, Riehl T, et al. (1998) Cyclooxygenase 2 is induced in colonic epithelial cells in inflammatory bowel disease. Gastroenterology 115: 297-306.
    • (1998) Gastroenterology , vol.115 , pp. 297-306
    • Singer, I.I.1    Kawka, D.W.2    Schloemann, S.3    Tessner, T.4    Riehl, T.5
  • 41
    • 0037851769 scopus 로고    scopus 로고
    • IKKbeta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide
    • Yang F, Tang E, Guan K, Wang CY, (2003) IKKbeta plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. J Immunol 170: 5630-5635.
    • (2003) J Immunol , vol.170 , pp. 5630-5635
    • Yang, F.1    Tang, E.2    Guan, K.3    Wang, C.Y.4
  • 42
    • 0031017618 scopus 로고    scopus 로고
    • MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1
    • Malinin NL, Boldin MP, Kovalenko AV, Wallach D, (1997) MAP3K-related kinase involved in NF-κB induction by TNF, CD95 and IL-1. Nature 385: 540-544.
    • (1997) Nature , vol.385 , pp. 540-544
    • Malinin, N.L.1    Boldin, M.P.2    Kovalenko, A.V.3    Wallach, D.4
  • 43
    • 0033568674 scopus 로고    scopus 로고
    • Curcumin blocks cytokine-mediated NF-κB activation and proinflammatory gene expression by inhibiting inhibitory factor I-κB kinase activity
    • Jobin C, Bradham CA, Russo MP, Juma B, Narula AS, et al. (1999) Curcumin blocks cytokine-mediated NF-κB activation and proinflammatory gene expression by inhibiting inhibitory factor I-κB kinase activity. J Immunol 163: 3474-3483.
    • (1999) J Immunol , vol.163 , pp. 3474-3483
    • Jobin, C.1    Bradham, C.A.2    Russo, M.P.3    Juma, B.4    Narula, A.S.5
  • 44
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden MS, Ghosh S, (2004) Signaling to NF-κB. Genes Dev 18: 2195-2224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 45
    • 1642553460 scopus 로고    scopus 로고
    • To be, or not to be: NF-κB is the answer-role of Rel/NF-κB in the regulation of apoptosis
    • Kucharczak J, Simmons MJ, Fan Y, Gélinas C, (2003) To be, or not to be: NF-κB is the answer-role of Rel/NF-κB in the regulation of apoptosis. Oncogene 22: 8961-8982.
    • (2003) Oncogene , vol.22 , pp. 8961-8982
    • Kucharczak, J.1    Simmons, M.J.2    Fan, Y.3    Gélinas, C.4
  • 46
    • 7344245990 scopus 로고    scopus 로고
    • High Fas ligand expression on lymphocytes in lesions of ulcerative colitis
    • Ueyama H, Kiyohara T, Sawada N, Isozaki K, Kitamura S, et al. (1998) High Fas ligand expression on lymphocytes in lesions of ulcerative colitis. Gut 43: 48-55.
    • (1998) Gut , vol.43 , pp. 48-55
    • Ueyama, H.1    Kiyohara, T.2    Sawada, N.3    Isozaki, K.4    Kitamura, S.5
  • 48
    • 11844283279 scopus 로고    scopus 로고
    • CD95 apoptosis resistance in certain cells can be overcome by noncanonical activation of caspase-8
    • Barnhart BC, Pietras EM, Geciras-Schimnich A, Salmena L, Sayama K, et al. (2005) CD95 apoptosis resistance in certain cells can be overcome by noncanonical activation of caspase-8. Cell Death Differ 12: 25-37.
    • (2005) Cell Death Differ , vol.12 , pp. 25-37
    • Barnhart, B.C.1    Pietras, E.M.2    Geciras-Schimnich, A.3    Salmena, L.4    Sayama, K.5
  • 49
    • 0037427412 scopus 로고    scopus 로고
    • Mechanisms of cytochrome C release by proapoptotic Bcl-2 family members
    • Scorrano L, Korsmeyer SJ, (2003) Mechanisms of cytochrome C release by proapoptotic Bcl-2 family members. Biochem Biophys Res Commun 304: 437-444.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 437-444
    • Scorrano, L.1    Korsmeyer, S.J.2
  • 50
    • 0033565302 scopus 로고    scopus 로고
    • Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance
    • Ina K, Itoh J, Fukushima K, Kusugami K, Yamaguchi T, et al. (1999) Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. J Immunol 63: 1081-1090.
    • (1999) J Immunol , vol.63 , pp. 1081-1090
    • Ina, K.1    Itoh, J.2    Fukushima, K.3    Kusugami, K.4    Yamaguchi, T.5
  • 52
    • 70350165074 scopus 로고    scopus 로고
    • Plasma transforming growth factor-β1 level in inflammatory bowel disease
    • Kilic ZMY, Ayaz S, Özin Y, Nadir I, Cakal B, et al. (2009) Plasma transforming growth factor-β1 level in inflammatory bowel disease. Turk J Gastroenterol 20: 165-170.
    • (2009) Turk J Gastroenterol , vol.20 , pp. 165-170
    • Kilic, Z.M.Y.1    Ayaz, S.2    Özin, Y.3    Nadir, I.4    Cakal, B.5
  • 54
    • 78650250592 scopus 로고    scopus 로고
    • Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways
    • Gorina R, Font-Nieves M, Márquez-Kisinousky L, Santalucia T, Planas AM, (2011) Astrocyte TLR4 activation induces a proinflammatory environment through the interplay between MyD88-dependent NFκB signaling, MAPK, and Jak1/Stat1 pathways. Glia 59: 242-255.
    • (2011) Glia , vol.59 , pp. 242-255
    • Gorina, R.1    Font-Nieves, M.2    Márquez-Kisinousky, L.3    Santalucia, T.4    Planas, A.M.5
  • 55
    • 26444605834 scopus 로고    scopus 로고
    • IKK/NF-κB signaling: balancing life and death-a new approach to cancer therapy
    • Luo JL, Kamata H, Karin M, (2005) IKK/NF-κB signaling: balancing life and death-a new approach to cancer therapy. J Clin Invest 115: 2625-2632.
    • (2005) J Clin Invest , vol.115 , pp. 2625-2632
    • Luo, J.L.1    Kamata, H.2    Karin, M.3
  • 56
    • 4043088499 scopus 로고    scopus 로고
    • IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer
    • Greten FR, Eckmann L, Greten TF, Park JM, Li ZW, et al. (2004) IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer. Cell 118: 285-296.
    • (2004) Cell , vol.118 , pp. 285-296
    • Greten, F.R.1    Eckmann, L.2    Greten, T.F.3    Park, J.M.4    Li, Z.W.5
  • 57
    • 0034322370 scopus 로고    scopus 로고
    • Suppression of NF-κB activity by sulfasalazine is mediated by direct inhibition of IκB kinases α and β
    • Weber CK, Liptay S, Wirth T, Adler G, Schmid RM, (2000) Suppression of NF-κB activity by sulfasalazine is mediated by direct inhibition of IκB kinases α and β. Gastroenterology 119: 1209-1218.
    • (2000) Gastroenterology , vol.119 , pp. 1209-1218
    • Weber, C.K.1    Liptay, S.2    Wirth, T.3    Adler, G.4    Schmid, R.M.5
  • 58
    • 78651391043 scopus 로고    scopus 로고
    • The research progress of Folium syringae leaves
    • Zhang LX, (2009) The research progress of Folium syringae leaves. Strait Pharmaceutical Journal 21: 20-23.
    • (2009) Strait Pharmaceutical Journal , vol.21 , pp. 20-23
    • Zhang, L.X.1


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