Importance of domain closure for the autoactivation of ERK2

Biochemistry

Volumn 50, Issue 37, 2011, Pages 8038-8048

  Barr, Daniel ^a,d   Oashi, Taiji ^b   Burkhard, Kimberly ^b   Lucius, Sarah ^a   Samadani, Ramin ^b   Zhang, Jun ^b   Shapiro, Paul ^b   MacKerell, Alexander D ^b   Van Der Vaart, Arjan ^c  

^a ARIZONA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

^d UTICA COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVITY REGULATION; AUTOACTIVATION; AUTOPHOSPHORYLATION; CELL DIVISIONS; CONSTITUTIVELY ACTIVES; EXTRACELLULAR SIGNAL-REGULATED KINASES 1 AND 2; HOMODIMERIZATION; MOLECULAR DYNAMICS SIMULATIONS; PROTEIN SURFACE;

CELL PROLIFERATION; FORECASTING; HYDROGEN BONDS; MOLECULAR DYNAMICS; PHOSPHORYLATION;

ENZYMES;

DOCKING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUTANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DIMERIZATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBSTRATE; HYDROGEN BOND; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING;

ENZYME ACTIVATION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 80052741666     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200503a     Document Type: Article

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