The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 48, 2006, Pages 18101-18106

  Emirick, Michelle A ^a,c   Lee, Thomas ^a,d   Starkey, Paul J ^a   Mumby, Marc C ^b   Resing, Katheryn A ^a   Ahn, Natalie G ^a  

^a UNIVERSITY OF COLORADO   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Allostery; Autoinhibition; Autophosphorylation; Hydrogen exchange; MAP kinase

Indexed keywords

HYDROGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; MUTANT PROTEIN;

ALLOSTERISM; AMINO TERMINAL SEQUENCE; ARTICLE; AUTOPHOSPHORYLATION; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME REGULATION; HYDROPHOBICITY; MOLECULAR INTERACTION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

ANIMALS; ENZYME ACTIVATION; GLUTAMINE; HYDROPHOBICITY; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MODELS, MOLECULAR; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; RATS;

PYRONIA TITHONUS;

EID: 33845327489     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0608849103     Document Type: Article

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