Differences in disease severity but similar telomere lengths in genetic subgroups of patients with telomerase and shelterin mutations

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Vulliamy, Tom J ^a   Kirwan, Michael J ^a   Beswick, Richard ^a   Hossain, Upal ^a   Baqai, Charlotte ^b   Ratcliffe, Anna ^a   Marsh, Judith ^c   Walne, Amanda ^a   Dokal, Inderjeet ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOPROTEIN; SHELTERIN; TELOMERASE; UNCLASSIFIED DRUG; SHELTERIN, HUMAN; TELOMERE BINDING PROTEIN; TERT PROTEIN, HUMAN;

ADULT; APLASTIC ANEMIA; BONE MARROW DEPRESSION; CANCER INCIDENCE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE SEVERITY; DKC1 GENE; DYSKERATOSIS CONGENITA; ENZYME ACTIVITY; GENE; GENE MUTATION; HUMAN; IN VITRO STUDY; MAJOR CLINICAL STUDY; ONSET AGE; REVIEW; TELOMERE; TELOMERE LENGTH; TERC GENE; TERT GENE; TINF2 GENE; UNITED KINGDOM; ADOLESCENT; ARTICLE; CHILD; GENETICS; HOSPITALIZATION; INFANT; MIDDLE AGED; MUTATION; PRESCHOOL CHILD; TELOMERE HOMEOSTASIS;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; HUMANS; INFANT; MIDDLE AGED; MUTATION; SEVERITY OF ILLNESS INDEX; TELOMERASE; TELOMERE HOMEOSTASIS; TELOMERE-BINDING PROTEINS; YOUNG ADULT;

EID: 80052725505     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024383     Document Type: Review

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