Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 4, 2009, Pages 1187-1192

  Calado, Rodrigo T ^a,g   Regal, Joshua A ^a   Hills, Mark ^e   Yewdell, William T ^a   Dalmazzo, Leandro F ^c   Zago, Marco A ^c   Lansdorp, Peter M ^e,f   Hogge, Donna ^e,f   Chanock, Stephen J ^b   Estey, Elihu H ^d   Falcão, Roberto P ^c   Young, Neal S ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e BRITISH COLUMBIA CANCER AGENCY   (Canada)

^f UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^g NONE   (United States)

Author keywords

Cancer; Dyskeratosis congenita; Risk factor; Telomere

Indexed keywords

TELOMERASE;

ACUTE GRANULOCYTIC LEUKEMIA; ADOLESCENT; ADULT; AGED; ARTICLE; BONE MARROW; CELL PROLIFERATION; CHILD; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; FEMALE; GENE MUTATION; GENETIC VARIABILITY; GENOMIC INSTABILITY; GERM LINE; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK FACTOR; STEM CELL; TELOMERE; TRISOMY 8;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMINO ACID SEQUENCE; CASE-CONTROL STUDIES; CELL LINE; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTATION; TELOMERASE; TELOMERE;

EID: 59049087610     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0807057106     Document Type: Article

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