Telomere length in leukocyte subpopulations of patients with aplastic anemia

Blood

Volumn 97, Issue 4, 2001, Pages 895-900

  Brummendorf T H ^a   Maciejewski, J P ^a   Mak, J ^a   Young, N S ^a   Lansdorp, P M ^a  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; APLASTIC ANEMIA; ARTICLE; BONE MARROW DEPRESSION; CELL PROLIFERATION; CHILD; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; GRANULOCYTE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOSUPPRESSIVE TREATMENT; MAJOR CLINICAL STUDY; MITOSIS; PANCYTOPENIA; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PRIORITY JOURNAL; TELOMERE;

EID: 0035865618     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.4.895     Document Type: Article

References (42)

1. The hematopoietic defect in aplastic anemia assessed by long-term marrow culture
2. Phenotypic and functional analysis of bone marrow progenitor cell compartment in bone marrow failure
3. Haemopoietic progenitor cells are reduced in aplastic anaemia
4. A severe and consistent deficit in marrow and circulating primitive hematopoietic cells (long-term culture-initiating cells) in acquired aplastic anemia
5. Quantitative analysis of cobblestone area-forming cells in bone marrow of patients with aplastic anemia by limiting dilution assay
6. The assessment of the hematopoietic reservoir after immunosuppressive therapy or bone marrow transplantation in severe aplastic anemia
7. Deficient reconstitution of early progenitors after allogeneic bone marrow transplantation
8. Long-term marrow culture in patients with aplastic anemia compared with marrow transplant recipients and normal controls
9. Long-lasting decrease of marrow and circulating long-term culture initiating cells after allogeneic bone marrow transplant
10. Structure and function of telomeres
11. Telomeres: Beginning to understand the end
12. Telomere dynamics and genome instability in human cancer
13. Telomeres shorten during ageing of human fibroblasts
14. Telomere reduction in human colorectal carcinoma and with ageing
15. A theory of marginotomy
16. Origin of concatameric T4 DNA
17. Telomere length regulation
18. Specific association of human telomerase activity with immortal cells and cancer
19. Telomerase activity in human germline and embryonic tissues and cells
20. Telomerase, cell immortality, and cancer
21. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
22. Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice
23. Longevity, stress response, and cancer in aging telomerase-deficient mice
24. Extension of life-span by introduction of telomerase into normal human cells
25. Recenstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
26. Ontogeny-related changes in proliferative potential of human hematopoietic cells
27. Evidence for a mitotic clock in human hematopoietic stem cells: Loss of telomeric DNA with age
28. Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants
29. In vivo telomere dynamics of human hematopoietic stem cells
30. Progressive telomere shortening in aplastic anemia
31. Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
32. Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood
33. Genetic determination of telomere size in humans: A twin study of three age groups
34. Prognostic implications of differences in telomere length between normal and malignant cells from patients with chronic myeloid leukemia measured by flow cytometry
35. Severe aplastic anemia: A prospective study of the effect of early marrow transplantation on acute mortality
36. Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes
37. Terminology and nomenclature for standardization in quantitative fluorescence cytometry
38. The rate of telomere sequence loss in human leukocytes varies with age
39. Asymmetric cell divisions sustain long-term hematopoiesis from single-sorted human fetal liver cells
40. Self-renewal of stem cells
41. Natural history of paroxysmal noctumal hemoglobinuria
42. Sustained long-term hematologic recovery despite a marked quantitative defect in the stem cell compartment of patients with aplastic anemia after immunosuppressive therapy