Beneficial effects of ethyl pyruvate through inhibiting high-mobility group box 1 expression and TLR4/NF-κB pathway after traumatic brain injury in the rat

Mediators of Inflammation

Volumn 2011, Issue , 2011, Pages

  Wang, Handong ^a   Su, Xingfen ^a   Zhao, Jinbing ^a   Pan, Hao ^a   Mao, Lei ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; PYRUVIC ACID DERIVATIVE; PYRUVIC ACID ETHYL ESTER; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; NEUROPROTECTIVE AGENT;

ADRENAL CORTEX CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BEAM WALKING TEST; BRAIN EDEMA; CELL COUNT; CLINICAL EVALUATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BINDING; DRUG MECHANISM; ENZYME INHIBITION; EXPERIMENTAL TEST; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRAUMATIC BRAIN INJURY; ANIMAL; BRAIN INJURY; DRUG ANTAGONISM; GENETICS; METABOLISM; NEUROPSYCHOLOGICAL TEST; NICK END LABELING; PATHOLOGY; PATHOPHYSIOLOGY; RANDOMIZATION; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BRAIN EDEMA; BRAIN INJURIES; HMGB1 PROTEIN; IN SITU NICK-END LABELING; MALE; NEUROPROTECTIVE AGENTS; NEUROPSYCHOLOGICAL TESTS; NF-KAPPA B; PYRUVATES; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY;

EID: 80052669019     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2011/807142     Document Type: Article

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