메뉴 건너뛰기




Volumn 13, Issue 5, 2013, Pages

Suppression of apoptosis inhibitor c-FLIP selectively eliminates breast cancer stem cell activity in response to the anti-cancer agent, TRAIL

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INHIBITOR; FLICE INHIBITORY PROTEIN; RECOMBINANT TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; SMALL INTERFERING RNA; CFLAR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN; ESTROGEN RECEPTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

EID: 80052662217     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr2945     Document Type: Article
Times cited : (81)

References (60)
  • 1
    • 58349104775 scopus 로고    scopus 로고
    • Oestrogen-receptor-positive breast cancer: towards bridging histopathological and molecular classifications
    • Badve S, Nakshatri H: Oestrogen-receptor-positive breast cancer: towards bridging histopathological and molecular classifications. J Clin Pathol 2009, 62:6-12.
    • (2009) J Clin Pathol , vol.62 , pp. 6-12
    • Badve, S.1    Nakshatri, H.2
  • 2
    • 56949108012 scopus 로고    scopus 로고
    • Her2-positive breast cancer: herceptin and beyond
    • Dean-Colomb W, Esteva FJ: Her2-positive breast cancer: herceptin and beyond. Eur J Cancer 2008, 44:2806-2812.
    • (2008) Eur J Cancer , vol.44 , pp. 2806-2812
    • Dean-Colomb, W.1    Esteva, F.J.2
  • 3
    • 54849434450 scopus 로고    scopus 로고
    • Current research topics in endocrine therapy for breast cancer
    • Yamashita H: Current research topics in endocrine therapy for breast cancer. Int J Clin Oncol 2008, 13:380-383.
    • (2008) Int J Clin Oncol , vol.13 , pp. 380-383
    • Yamashita, H.1
  • 4
    • 52549087785 scopus 로고    scopus 로고
    • Cancer stem cells in solid tumours: accumulating evidence and unresolved questions
    • Visvader JE, Lindeman GJ: Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 2008, 8:755-768.
    • (2008) Nat Rev Cancer , vol.8 , pp. 755-768
    • Visvader, J.E.1    Lindeman, G.J.2
  • 10
    • 34548758597 scopus 로고    scopus 로고
    • Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-induced mammary tumors
    • Liu JC, Deng T, Lehal RS, Kim J, Zacksenhaus E: Identification of tumorsphere- and tumor-initiating cells in HER2/Neu-induced mammary tumors. Cancer Res 2007, 67:8671-8681.
    • (2007) Cancer Res , vol.67 , pp. 8671-8681
    • Liu, J.C.1    Deng, T.2    Lehal, R.S.3    Kim, J.4    Zacksenhaus, E.5
  • 11
    • 34648821257 scopus 로고    scopus 로고
    • Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
    • Stingl J, Caldas C: Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat Rev Cancer 2007, 7:791-799.
    • (2007) Nat Rev Cancer , vol.7 , pp. 791-799
    • Stingl, J.1    Caldas, C.2
  • 12
    • 54249086214 scopus 로고    scopus 로고
    • The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis
    • Vaillant F, Asselin-Labat ML, Shackleton M, Forrest NC, Lindeman GJ, Visvader JE: The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis. Cancer Res 2008, 68:7711-7717.
    • (2008) Cancer Res , vol.68 , pp. 7711-7717
    • Vaillant, F.1    Asselin-Labat, M.L.2    Shackleton, M.3    Forrest, N.C.4    Lindeman, G.J.5    Visvader, J.E.6
  • 13
    • 72749103664 scopus 로고    scopus 로고
    • Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis
    • Visvader JE: Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis. Genes Dev 2009, 23:2563-2577.
    • (2009) Genes Dev , vol.23 , pp. 2563-2577
    • Visvader, J.E.1
  • 16
    • 41049112098 scopus 로고    scopus 로고
    • TRAIL and cancer therapy
    • Kruyt FA: TRAIL and cancer therapy. Cancer Lett 2008, 263:14-25.
    • (2008) Cancer Lett , vol.263 , pp. 14-25
    • Kruyt, F.A.1
  • 17
    • 34548132882 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its therapeutic potential in breast and gynecologic cancers
    • Kendrick JE, Estes JM, Straughn JM Jr, Alvarez RD, Buchsbaum DJ: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its therapeutic potential in breast and gynecologic cancers. Gynecol Oncol 2007, 106:614-621.
    • (2007) Gynecol Oncol , vol.106 , pp. 614-621
    • Kendrick, J.E.1    Estes, J.M.2    Straughn, J.M.3    Alvarez, R.D.4    Buchsbaum, D.J.5
  • 21
    • 0037273848 scopus 로고    scopus 로고
    • Apo2L/TRAIL and its death and decoy receptors
    • LeBlanc HN, Ashkenazi A: Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 2003, 10:66-75.
    • (2003) Cell Death Differ , vol.10 , pp. 66-75
    • LeBlanc, H.N.1    Ashkenazi, A.2
  • 22
    • 77955850542 scopus 로고    scopus 로고
    • 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells
    • Bijangi-Vishehsaraei K, Saadatzadeh MR, Huang S, Murphy MP, Safa AR: 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide (CMH) targets mRNA of the c-FLIP variants and induces apoptosis in MCF-7 human breast cancer cells. Mol Cell Biochem 2010, 342:133-142.
    • (2010) Mol Cell Biochem , vol.342 , pp. 133-142
    • Bijangi-Vishehsaraei, K.1    Saadatzadeh, M.R.2    Huang, S.3    Murphy, M.P.4    Safa, A.R.5
  • 23
    • 27744526342 scopus 로고    scopus 로고
    • A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells
    • Bockbrader KM, Tan M, Sun Y: A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells. Oncogene 2005, 24:7381-7388.
    • (2005) Oncogene , vol.24 , pp. 7381-7388
    • Bockbrader, K.M.1    Tan, M.2    Sun, Y.3
  • 25
    • 0035874898 scopus 로고    scopus 로고
    • Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2
    • Cuello M, Ettenberg SA, Clark AS, Keane MM, Posner RH, Nau MM, Dennis PA, Lipkowitz S: Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2. Cancer Res 2001, 61:4892-4900.
    • (2001) Cancer Res , vol.61 , pp. 4892-4900
    • Cuello, M.1    Ettenberg, S.A.2    Clark, A.S.3    Keane, M.M.4    Posner, R.H.5    Nau, M.M.6    Dennis, P.A.7    Lipkowitz, S.8
  • 28
    • 76049125661 scopus 로고    scopus 로고
    • The sesquiterpene lactone eupatolide sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression
    • Lee J, Hwangbo C, Lee JJ, Seo J, Lee JH: The sesquiterpene lactone eupatolide sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression. Oncol Rep 2009, 23:229-237.
    • (2009) Oncol Rep , vol.23 , pp. 229-237
    • Lee, J.1    Hwangbo, C.2    Lee, J.J.3    Seo, J.4    Lee, J.H.5
  • 30
    • 44849129481 scopus 로고    scopus 로고
    • Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism
    • Ortiz-Ferron G, Yerbes R, Eramo A, Lopez-Perez AI, De Maria R, Lopez-Rivas A: Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism. Cell Res 2008, 18:664-676.
    • (2008) Cell Res , vol.18 , pp. 664-676
    • Ortiz-Ferron, G.1    Yerbes, R.2    Eramo, A.3    Lopez-Perez, A.I.4    De Maria, R.5    Lopez-Rivas, A.6
  • 31
    • 33749004024 scopus 로고    scopus 로고
    • Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells
    • Palacios C, Yerbes R, Lopez-Rivas A: Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells. Cancer Res 2006, 66:8858-8869.
    • (2006) Cancer Res , vol.66 , pp. 8858-8869
    • Palacios, C.1    Yerbes, R.2    Lopez-Rivas, A.3
  • 32
    • 77950861324 scopus 로고    scopus 로고
    • Mitotic arrest and JNK-induced proteasomal degradation of FLIP and Mcl-1 are key events in the sensitization of breast tumor cells to TRAIL by antimicrotubule agents
    • Sanchez-Perez T, Ortiz-Ferron G, Lopez-Rivas A: Mitotic arrest and JNK-induced proteasomal degradation of FLIP and Mcl-1 are key events in the sensitization of breast tumor cells to TRAIL by antimicrotubule agents. Cell Death Differ 2009, 17:883-894.
    • (2009) Cell Death Differ , vol.17 , pp. 883-894
    • Sanchez-Perez, T.1    Ortiz-Ferron, G.2    Lopez-Rivas, A.3
  • 33
    • 20744433491 scopus 로고    scopus 로고
    • Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1
    • Shetty S, Graham BA, Brown JG, Hu X, Vegh-Yarema N, Harding G, Paul JT, Gibson SB: Transcription factor NF-kappaB differentially regulates death receptor 5 expression involving histone deacetylase 1. Mol Cell Biol 2005, 25:5404-5416.
    • (2005) Mol Cell Biol , vol.25 , pp. 5404-5416
    • Shetty, S.1    Graham, B.A.2    Brown, J.G.3    Hu, X.4    Vegh-Yarema, N.5    Harding, G.6    Paul, J.T.7    Gibson, S.B.8
  • 34
    • 32344451665 scopus 로고    scopus 로고
    • Intracellular mechanisms mediating tocotrienol-induced apoptosis in neoplastic mammary epithelial cells
    • Sylvester PW, Shah S: Intracellular mechanisms mediating tocotrienol-induced apoptosis in neoplastic mammary epithelial cells. Asia Pac J Clin Nutr 2005, 14:366-373.
    • (2005) Asia Pac J Clin Nutr , vol.14 , pp. 366-373
    • Sylvester, P.W.1    Shah, S.2
  • 35
    • 33750535200 scopus 로고    scopus 로고
    • Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy
    • Xu J, Zhou JY, Wu GS: Tumor necrosis factor-related apoptosis-inducing ligand is required for tumor necrosis factor alpha-mediated sensitization of human breast cancer cells to chemotherapy. Cancer Res 2006, 66:10092-10099.
    • (2006) Cancer Res , vol.66 , pp. 10092-10099
    • Xu, J.1    Zhou, J.Y.2    Wu, G.S.3
  • 36
    • 41949094367 scopus 로고    scopus 로고
    • FLIP as an anti-cancer therapeutic target
    • Yang JK: FLIP as an anti-cancer therapeutic target. Yonsei Med J 2008, 49:19-27.
    • (2008) Yonsei Med J , vol.49 , pp. 19-27
    • Yang, J.K.1
  • 37
    • 70350228525 scopus 로고    scopus 로고
    • Down-regulation of c-FLIP Enhances death of cancer cells by smac mimetic compound
    • Cheung HH, Mahoney DJ, Lacasse EC, Korneluk RG: Down-regulation of c-FLIP Enhances death of cancer cells by smac mimetic compound. Cancer Res 2009, 69:7729-7738.
    • (2009) Cancer Res , vol.69 , pp. 7729-7738
    • Cheung, H.H.1    Mahoney, D.J.2    Lacasse, E.C.3    Korneluk, R.G.4
  • 38
    • 56549112480 scopus 로고    scopus 로고
    • c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells
    • Day TW, Huang S, Safa AR: c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells. Biochem Pharmacol 2008, 76:1694-1704.
    • (2008) Biochem Pharmacol , vol.76 , pp. 1694-1704
    • Day, T.W.1    Huang, S.2    Safa, A.R.3
  • 39
    • 71949119903 scopus 로고    scopus 로고
    • c-FLIP gene silencing eliminates tumor cells in breast cancer xenografts without affecting stromal cells
    • Day TW, Sinn AL, Huang S, Pollok KE, Sandusky GE, Safa AR: c-FLIP gene silencing eliminates tumor cells in breast cancer xenografts without affecting stromal cells. Anticancer Res 2009, 29:3883-3886.
    • (2009) Anticancer Res , vol.29 , pp. 3883-3886
    • Day, T.W.1    Sinn, A.L.2    Huang, S.3    Pollok, K.E.4    Sandusky, G.E.5    Safa, A.R.6
  • 41
    • 0036598992 scopus 로고    scopus 로고
    • Targeting death and decoy receptors of the tumour-necrosis factor superfamily
    • Ashkenazi A: Targeting death and decoy receptors of the tumour-necrosis factor superfamily. Nat Rev Cancer 2002, 2:420-430.
    • (2002) Nat Rev Cancer , vol.2 , pp. 420-430
    • Ashkenazi, A.1
  • 42
    • 23744456144 scopus 로고    scopus 로고
    • An essential role for c-FLIP in the efficient development of mature T lymphocytes
    • Zhang N, He YW: An essential role for c-FLIP in the efficient development of mature T lymphocytes. J Exp Med 2005, 202:395-404.
    • (2005) J Exp Med , vol.202 , pp. 395-404
    • Zhang, N.1    He, Y.W.2
  • 44
    • 33750470097 scopus 로고    scopus 로고
    • CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells
    • Sleeman KE, Kendrick H, Ashworth A, Isacke CM, Smalley MJ: CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells. Breast Cancer Res 2006, 8:R7.
    • (2006) Breast Cancer Res , vol.8 , pp. R7
    • Sleeman, K.E.1    Kendrick, H.2    Ashworth, A.3    Isacke, C.M.4    Smalley, M.J.5
  • 47
    • 77957591579 scopus 로고    scopus 로고
    • Targeting breast cancer stem cells
    • Liu S, Wicha MS: Targeting breast cancer stem cells. J Clin Oncol 2010, 28:4006-4012.
    • (2010) J Clin Oncol , vol.28 , pp. 4006-4012
    • Liu, S.1    Wicha, M.S.2
  • 48
    • 54049096261 scopus 로고    scopus 로고
    • HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion
    • Korkaya H, Paulson A, Iovino F, Wicha MS: HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 2008, 27:6120-6130.
    • (2008) Oncogene , vol.27 , pp. 6120-6130
    • Korkaya, H.1    Paulson, A.2    Iovino, F.3    Wicha, M.S.4
  • 51
    • 12744261484 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies
    • Inoue S, MacFarlane M, Harper N, Wheat LM, Dyer MJ, Cohen GM: Histone deacetylase inhibitors potentiate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in lymphoid malignancies. Cell Death Differ 2004, 11:S193-206.
    • (2004) Cell Death Differ , vol.11 , pp. S193-206
    • Inoue, S.1    MacFarlane, M.2    Harper, N.3    Wheat, L.M.4    Dyer, M.J.5    Cohen, G.M.6
  • 53
    • 35348877298 scopus 로고    scopus 로고
    • Barriers to effective TRAIL-targeted therapy of malignancy
    • Dyer MJ, MacFarlane M, Cohen GM: Barriers to effective TRAIL-targeted therapy of malignancy. J Clin Oncol 2007, 25:4505-4506.
    • (2007) J Clin Oncol , vol.25 , pp. 4505-4506
    • Dyer, M.J.1    MacFarlane, M.2    Cohen, G.M.3
  • 58
    • 42549144516 scopus 로고    scopus 로고
    • Chemotherapy-resistant side-population of colon cancer cells has a higher sensitivity to TRAIL than the non-SP, a higher expression of c-Myc and TRAIL-receptor DR4
    • Sussman RT, Ricci MS, Hart LS, Sun SY, El-Deiry WS: Chemotherapy-resistant side-population of colon cancer cells has a higher sensitivity to TRAIL than the non-SP, a higher expression of c-Myc and TRAIL-receptor DR4. Cancer Biol Ther 2007, 6:1490-1495.
    • (2007) Cancer Biol Ther , vol.6 , pp. 1490-1495
    • Sussman, R.T.1    Ricci, M.S.2    Hart, L.S.3    Sun, S.Y.4    El-Deiry, W.S.5
  • 60
    • 27644573005 scopus 로고    scopus 로고
    • Cellular IAP1 regulates TRAIL-induced apoptosis in human fetal cortical neural progenitor cells
    • Peng H, Huang Y, Duan Z, Erdmann N, Xu D, Herek S, Zheng J: Cellular IAP1 regulates TRAIL-induced apoptosis in human fetal cortical neural progenitor cells. J Neurosci Res 2005, 82:295-305.
    • (2005) J Neurosci Res , vol.82 , pp. 295-305
    • Peng, H.1    Huang, Y.2    Duan, Z.3    Erdmann, N.4    Xu, D.5    Herek, S.6    Zheng, J.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.