메뉴 건너뛰기




Volumn 72, Issue 4, 2011, Pages 604-618

Current concepts of platelet activation: Possibilities for therapeutic modulation of heterotypic vs. homotypic aggregation

Author keywords

Aspirin; Heterotypic aggregation; Homotypic aggregation; Platelet activation; Thienopyridines

Indexed keywords

ACETYLSALICYLIC ACID; ADENYLATE CYCLASE; CANGRELOR; CLOPIDOGREL; PRASUGREL; TICAGRELOR; TICLOPIDINE;

EID: 80052623218     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2011.03906.x     Document Type: Review
Times cited : (20)

References (152)
  • 1
    • 0032483550 scopus 로고    scopus 로고
    • Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow
    • Savage B, Almus-Jacobs F, Ruggeri ZM. Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow. Cell 1998; 94: 657-66.
    • (1998) Cell , vol.94 , pp. 657-666
    • Savage, B.1    Almus-Jacobs, F.2    Ruggeri, Z.M.3
  • 2
    • 0015993803 scopus 로고
    • Decreased adhesion of platelet to subendothelium in von Willebrand's disease
    • Tschopp TB, Weiss HJ, Baumgartner HR. Decreased adhesion of platelet to subendothelium in von Willebrand's disease. J Lab Clin Med 1973; 83: 296-300.
    • (1973) J Lab Clin Med , vol.83 , pp. 296-300
    • Tschopp, T.B.1    Weiss, H.J.2    Baumgartner, H.R.3
  • 3
    • 0018118813 scopus 로고
    • Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate-dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome
    • Weiss HJ, Turitto VT, Baumgartner HR. Effect of shear rate on platelet interaction with subendothelium in citrated and native blood. I. Shear rate-dependent decrease of adhesion in von Willebrand's disease and the Bernard-Soulier syndrome. J Lab Clin Med 1978; 92: 750-64.
    • (1978) J Lab Clin Med , vol.92 , pp. 750-764
    • Weiss, H.J.1    Turitto, V.T.2    Baumgartner, H.R.3
  • 4
    • 0023185957 scopus 로고
    • The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering
    • Isenberg WM, McEver RP, Phillips DR, Shuman MA, Bainton DF. The platelet fibrinogen receptor: an immunogold-surface replica study of agonist-induced ligand binding and receptor clustering. J Cell Biol 1987; 104: 1655-63.
    • (1987) J Cell Biol , vol.104 , pp. 1655-1663
    • Isenberg, W.M.1    McEver, R.P.2    Phillips, D.R.3    Shuman, M.A.4    Bainton, D.F.5
  • 5
    • 0024532116 scopus 로고
    • Molecular mechanisms of platelet activation
    • Siess W. Molecular mechanisms of platelet activation. Physiol Rev 1989; 69: 58-178.
    • (1989) Physiol Rev , vol.69 , pp. 58-178
    • Siess, W.1
  • 8
    • 0037035464 scopus 로고    scopus 로고
    • Platelet-monocyte aggregates: bridging thrombosis and inflammation
    • Freedeman JE, Loscalzo J. Platelet-monocyte aggregates: bridging thrombosis and inflammation. Circulation 2002; 105: 2130-2.
    • (2002) Circulation , vol.105 , pp. 2130-2132
    • Freedeman, J.E.1    Loscalzo, J.2
  • 9
    • 0035949524 scopus 로고    scopus 로고
    • Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet P-selectin: studies in baboons, human coronary intervention, and human myocardial infarction
    • Michelson D, Barnard MR, Krueger LA, Valeri CR, Furman MI. Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet P-selectin: studies in baboons, human coronary intervention, and human myocardial infarction. Circulation 2001; 104: 1533-7.
    • (2001) Circulation , vol.104 , pp. 1533-1537
    • Michelson, D.1    Barnard, M.R.2    Krueger, L.A.3    Valeri, C.R.4    Furman, M.I.5
  • 10
    • 0037035461 scopus 로고    scopus 로고
    • Increased platelet binding to circulating monocytes in acute coronary syndromes
    • Sarma J, Laan CA, Alam S, Jha A, Fox KA, Dransfield I. Increased platelet binding to circulating monocytes in acute coronary syndromes. Circulation 2002; 105: 2166-71.
    • (2002) Circulation , vol.105 , pp. 2166-2171
    • Sarma, J.1    Laan, C.A.2    Alam, S.3    Jha, A.4    Fox, K.A.5    Dransfield, I.6
  • 13
    • 0035726226 scopus 로고    scopus 로고
    • Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis
    • Joseph JE, Harrison P, Mackie IJ, Isenberg DA, Machin SJ. Increased circulating platelet-leucocyte complexes and platelet activation in patients with antiphospholipid syndrome, systemic lupus erythematosus and rheumatoid arthritis. Br J Haematol 2001; 115: 451-9.
    • (2001) Br J Haematol , vol.115 , pp. 451-459
    • Joseph, J.E.1    Harrison, P.2    Mackie, I.J.3    Isenberg, D.A.4    Machin, S.J.5
  • 14
    • 0035061393 scopus 로고    scopus 로고
    • Increased circulating platelet-leukocyte aggregates in myeloproliferative disorders is correlated to previous thrombosis, platelet activation and platelet count
    • Jensen MK, de Nully Brown P, Lund BV, Nielsen OJ, Hasselbalch HC. Increased circulating platelet-leukocyte aggregates in myeloproliferative disorders is correlated to previous thrombosis, platelet activation and platelet count. Eur J Haematol 2001; 66: 143-51.
    • (2001) Eur J Haematol , vol.66 , pp. 143-151
    • Jensen, M.K.1    de Nully Brown, P.2    Lund, B.V.3    Nielsen, O.J.4    Hasselbalch, H.C.5
  • 15
    • 0036042517 scopus 로고    scopus 로고
    • Activated monocytes and platelet-monocyte aggregates in patients with sickle cell disease
    • Wun T, Cordoba M, Rangaswami A, Cheung AW, Paglieroni T. Activated monocytes and platelet-monocyte aggregates in patients with sickle cell disease. Clin Lab Haematol 2002; 24: 81-8.
    • (2002) Clin Lab Haematol , vol.24 , pp. 81-88
    • Wun, T.1    Cordoba, M.2    Rangaswami, A.3    Cheung, A.W.4    Paglieroni, T.5
  • 19
    • 0037374428 scopus 로고    scopus 로고
    • Clopidogrel but not aspirin reduces P-selectin expression and formation of platelet-leukocyte aggregates in patients with atherosclerotic vascular disease
    • Klinkhardt U, Bauersachs R, Adams J, Graff J, Lindhoff-Last E, Harder S. Clopidogrel but not aspirin reduces P-selectin expression and formation of platelet-leukocyte aggregates in patients with atherosclerotic vascular disease. Clin Pharmacol Ther 2003; 73: 232-41.
    • (2003) Clin Pharmacol Ther , vol.73 , pp. 232-241
    • Klinkhardt, U.1    Bauersachs, R.2    Adams, J.3    Graff, J.4    Lindhoff-Last, E.5    Harder, S.6
  • 20
    • 31044445108 scopus 로고    scopus 로고
    • Thrombus formation in vivo
    • Furie B, Furie BC. Thrombus formation in vivo. J Clin Invest 2005; 115: 3355-62.
    • (2005) J Clin Invest , vol.115 , pp. 3355-3362
    • Furie, B.1    Furie, B.C.2
  • 22
    • 59649100859 scopus 로고    scopus 로고
    • Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases
    • van Gils JM, Zwaginga JJ, Hordijk PL. Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases. J Leukoc Biol 2009; 85: 195-204.
    • (2009) J Leukoc Biol , vol.85 , pp. 195-204
    • van Gils, J.M.1    Zwaginga, J.J.2    Hordijk, P.L.3
  • 24
    • 33846240313 scopus 로고    scopus 로고
    • Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation
    • Maxwell MJ, Westein E, Nesbitt WS, Giuliano S, Dopheide SM, Jackson SP. Identification of a 2-stage platelet aggregation process mediating shear-dependent thrombus formation. Blood 2007; 109: 566-76.
    • (2007) Blood , vol.109 , pp. 566-576
    • Maxwell, M.J.1    Westein, E.2    Nesbitt, W.S.3    Giuliano, S.4    Dopheide, S.M.5    Jackson, S.P.6
  • 25
    • 13344295095 scopus 로고    scopus 로고
    • Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor
    • Savage B, Saldivar E, Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell 1996; 84: 289-97.
    • (1996) Cell , vol.84 , pp. 289-297
    • Savage, B.1    Saldivar, E.2    Ruggeri, Z.M.3
  • 27
    • 33748704252 scopus 로고    scopus 로고
    • Activation-independent platelet adhesion and aggregation under elevated shear stress
    • Ruggeri ZM, Orje JN, Habermann R, Federici AB, Reininger AJ. Activation-independent platelet adhesion and aggregation under elevated shear stress. Blood 2006; 108: 1903-10.
    • (2006) Blood , vol.108 , pp. 1903-1910
    • Ruggeri, Z.M.1    Orje, J.N.2    Habermann, R.3    Federici, A.B.4    Reininger, A.J.5
  • 28
    • 0020035003 scopus 로고
    • Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen
    • Nachman RL, Leung LL. Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen. J Clin Invest 1982; 69: 263-9.
    • (1982) J Clin Invest , vol.69 , pp. 263-269
    • Nachman, R.L.1    Leung, L.L.2
  • 30
    • 0030748125 scopus 로고    scopus 로고
    • Mechanisms initiating platelet thrombus formation
    • Ruggeri ZM. Mechanisms initiating platelet thrombus formation. Thromb Haemost 1997; 78: 611-6.
    • (1997) Thromb Haemost , vol.78 , pp. 611-616
    • Ruggeri, Z.M.1
  • 31
    • 0033838314 scopus 로고    scopus 로고
    • Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen
    • Ni H, Denis CV, Subbarao S, Degen JL, Sato TN, Hynes RO, Wagner DD. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest 2000; 106: 385-92.
    • (2000) J Clin Invest , vol.106 , pp. 385-392
    • Ni, H.1    Denis, C.V.2    Subbarao, S.3    Degen, J.L.4    Sato, T.N.5    Hynes, R.O.6    Wagner, D.D.7
  • 32
    • 34147139988 scopus 로고    scopus 로고
    • Thrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model
    • Dubois C, Panicot-Dubois L, Gainor JF, Furie BC, Furie B. Thrombin-initiated platelet activation in vivo is vWF independent during thrombus formation in a laser injury model. J Clin Invest 2007; 117: 953-60.
    • (2007) J Clin Invest , vol.117 , pp. 953-960
    • Dubois, C.1    Panicot-Dubois, L.2    Gainor, J.F.3    Furie, B.C.4    Furie, B.5
  • 34
    • 0036913378 scopus 로고    scopus 로고
    • The vulnerable plaque and acute coronary syndromes
    • Corti R, Farkouh ME, Badimon JJ. The vulnerable plaque and acute coronary syndromes. Am J Med 2002; 113: 668-80.
    • (2002) Am J Med , vol.113 , pp. 668-680
    • Corti, R.1    Farkouh, M.E.2    Badimon, J.J.3
  • 35
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 2002; 420: 868-74.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 37
    • 33947322186 scopus 로고    scopus 로고
    • Glycoprotein Ibα inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques
    • Penz SM, Reininger AJ, Toth O, Deckmyn H, Brandl R, Siess W. Glycoprotein Ibα inhibition and ADP receptor antagonists, but not aspirin, reduce platelet thrombus formation in flowing blood exposed to atherosclerotic plaques. Thromb Haemost 2007; 97: 435-43.
    • (2007) Thromb Haemost , vol.97 , pp. 435-443
    • Penz, S.M.1    Reininger, A.J.2    Toth, O.3    Deckmyn, H.4    Brandl, R.5    Siess, W.6
  • 38
    • 33750941414 scopus 로고    scopus 로고
    • The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis
    • Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD. The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proc Natl Acad Sci USA 2007; 103: 16900-5.
    • (2007) Proc Natl Acad Sci USA , vol.103 , pp. 16900-16905
    • Bergmeier, W.1    Piffath, C.L.2    Goerge, T.3    Cifuni, S.M.4    Ruggeri, Z.M.5    Ware, J.6    Wagner, D.D.7
  • 39
    • 34447593677 scopus 로고
    • Über einen neuen Formbestandteil des Blutes und dessen Rolle bei der Thrombose und Blutgerinnung
    • Bizzozero J. Über einen neuen Formbestandteil des Blutes und dessen Rolle bei der Thrombose und Blutgerinnung. Virchow's Arch Path Anat Physiol Klin Med 1882; 90: 261-332.
    • (1882) Virchow's Arch Path Anat Physiol Klin Med , vol.90 , pp. 261-332
    • Bizzozero, J.1
  • 40
    • 33645450196 scopus 로고    scopus 로고
    • Max Schultze (1865), G. Bizzozero (1882) and the discovery of the platelet
    • Brewer DB. Max Schultze (1865), G. Bizzozero (1882) and the discovery of the platelet. Br J Haematol 2006; 133: 251-8.
    • (2006) Br J Haematol , vol.133 , pp. 251-258
    • Brewer, D.B.1
  • 41
    • 0030221129 scopus 로고    scopus 로고
    • Leukocyte activation with platelet adhesion after coronary angioplasty: a mechanism for recurrent disease
    • Mickelson JK, Lakkis NM, Villarreal-Levy G, Hughes BJ, Smith CW. Leukocyte activation with platelet adhesion after coronary angioplasty: a mechanism for recurrent disease. J Am Coll Cardiol 1996; 28: 345-53.
    • (1996) J Am Coll Cardiol , vol.28 , pp. 345-353
    • Mickelson, J.K.1    Lakkis, N.M.2    Villarreal-Levy, G.3    Hughes, B.J.4    Smith, C.W.5
  • 42
    • 33846118743 scopus 로고    scopus 로고
    • Platelets as immune cells: bridging inflammation and cardiovascular disease
    • von Hundelshausen P, Weber C. Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ Res 2007; 100: 27-40.
    • (2007) Circ Res , vol.100 , pp. 27-40
    • von Hundelshausen, P.1    Weber, C.2
  • 44
    • 0346672401 scopus 로고    scopus 로고
    • P-selectin, tissue factor and CD40 ligand expression on platelet-leucocyte conjugates in the presence of a GPIIb/IIIa antagonist
    • Zhao L, Bath PM, May J, Lösche W, Heptinstall S. P-selectin, tissue factor and CD40 ligand expression on platelet-leucocyte conjugates in the presence of a GPIIb/IIIa antagonist. Platelets 2003; 14: 473-80.
    • (2003) Platelets , vol.14 , pp. 473-480
    • Zhao, L.1    Bath, P.M.2    May, J.3    Lösche, W.4    Heptinstall, S.5
  • 45
    • 0022612914 scopus 로고
    • Platelet-leukocyte interaction: selective binding of thrombin-stimulated platelets to human monocytes, polymorphonuclear leukocytes, and related cell lines
    • Jungi TW, Spycher MO, Nydegger UE, Barandun S. Platelet-leukocyte interaction: selective binding of thrombin-stimulated platelets to human monocytes, polymorphonuclear leukocytes, and related cell lines. Blood 1986; 67: 629-36.
    • (1986) Blood , vol.67 , pp. 629-636
    • Jungi, T.W.1    Spycher, M.O.2    Nydegger, U.E.3    Barandun, S.4
  • 46
    • 0026045724 scopus 로고
    • Activated and unactivated platelet adhesion to monocytes and neutrophils
    • Rinder HM, Bonan JL, Rinder CS, Ault KA, Smith BR. Activated and unactivated platelet adhesion to monocytes and neutrophils. Blood 1991; 78: 1760-9.
    • (1991) Blood , vol.78 , pp. 1760-1769
    • Rinder, H.M.1    Bonan, J.L.2    Rinder, C.S.3    Ault, K.A.4    Smith, B.R.5
  • 47
    • 0025090039 scopus 로고
    • GMP-140 mediates adhesion of stimulated platelets to neutrophils
    • Hamburger SA, McEver RP. GMP-140 mediates adhesion of stimulated platelets to neutrophils. Blood 1990; 75: 550-4.
    • (1990) Blood , vol.75 , pp. 550-554
    • Hamburger, S.A.1    McEver, R.P.2
  • 48
    • 0024357563 scopus 로고
    • PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes
    • Larsent E, Celi A, Gilbert GE, Furie BC, Erban JK, Bonfanti R, Wagner DD, Furie' B. PADGEM protein: a receptor that mediates the interaction of activated platelets with neutrophils and monocytes. Cell 1989; 59: 305-12.
    • (1989) Cell , vol.59 , pp. 305-312
    • Larsent, E.1    Celi, A.2    Gilbert, G.E.3    Furie, B.C.4    Erban, J.K.5    Bonfanti, R.6    Wagner, D.D.7    Furie', B.8
  • 49
    • 0032949518 scopus 로고    scopus 로고
    • The biology of P-selectin glycoprotein ligand-1: its role as a selectin counterreceptor in leukocyte-endothelial and leukocyte-platelet interaction
    • Yang J, Furie BC, Furie B. The biology of P-selectin glycoprotein ligand-1: its role as a selectin counterreceptor in leukocyte-endothelial and leukocyte-platelet interaction. Thromb Haemost 1999; 81: 1-7.
    • (1999) Thromb Haemost , vol.81 , pp. 1-7
    • Yang, J.1    Furie, B.C.2    Furie, B.3
  • 50
    • 0035676677 scopus 로고    scopus 로고
    • Identification of P-selectin glycoprotein ligand-1 as a useful marker in acute myeloid leukaemias
    • Kappelmayer J, Kiss A, Karaaszi E, Veszpreami A, Jako J, Kiss C. Identification of P-selectin glycoprotein ligand-1 as a useful marker in acute myeloid leukaemias. Br J Haematol 2001; 115: 903-9.
    • (2001) Br J Haematol , vol.115 , pp. 903-909
    • Kappelmayer, J.1    Kiss, A.2    Karaaszi, E.3    Veszpreami, A.4    Jako, J.5    Kiss, C.6
  • 51
    • 0028035107 scopus 로고
    • Induction of superoxide anion production from monocytes and neutrophils by activated platelets through the P-selectin-sialyl Lewis X interaction
    • Tsuji T, Nagata K, Koike J, Todoroki N, Irimura T. Induction of superoxide anion production from monocytes and neutrophils by activated platelets through the P-selectin-sialyl Lewis X interaction. J Leukoc Biol 1994; 56: 583-7.
    • (1994) J Leukoc Biol , vol.56 , pp. 583-587
    • Tsuji, T.1    Nagata, K.2    Koike, J.3    Todoroki, N.4    Irimura, T.5
  • 52
    • 0030661712 scopus 로고    scopus 로고
    • Engagement of P-selectin glycoprotein ligand-1 enhances tyrosine phosphorylation and activates mitogen-activated protein kinases in human neutrophils
    • Hidari KI, Weyrich AS, Zimmerman GA, McEver RP. Engagement of P-selectin glycoprotein ligand-1 enhances tyrosine phosphorylation and activates mitogen-activated protein kinases in human neutrophils. J Biol Chem 1997; 272: 28750-6.
    • (1997) J Biol Chem , vol.272 , pp. 28750-28756
    • Hidari, K.I.1    Weyrich, A.S.2    Zimmerman, G.A.3    McEver, R.P.4
  • 54
    • 0031066763 scopus 로고    scopus 로고
    • T cell adhesion to P-selectin induces tyrosine phosphorylation of pp125 focal adhesion kinase and other substrates
    • Haller H, Kunzendorf U, Sacherer K, Lindschau C, Walz G, Distler A, Luft FC. T cell adhesion to P-selectin induces tyrosine phosphorylation of pp125 focal adhesion kinase and other substrates. J Immunol 1997; 158: 1061-7.
    • (1997) J Immunol , vol.158 , pp. 1061-1067
    • Haller, H.1    Kunzendorf, U.2    Sacherer, K.3    Lindschau, C.4    Walz, G.5    Distler, A.6    Luft, F.C.7
  • 56
    • 59649100859 scopus 로고    scopus 로고
    • Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases
    • van Gils JM, Zwaginga JJ, Hordijk PL. Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases. J Leukoc Biol 2009; 85: 195-204.
    • (2009) J Leukoc Biol , vol.85 , pp. 195-204
    • van Gils, J.M.1    Zwaginga, J.J.2    Hordijk, P.L.3
  • 58
    • 0024514869 scopus 로고
    • Immunocytochemical localization of platelet granule proteins
    • Sixma JJ, Slot J-W, Geuze HJ. Immunocytochemical localization of platelet granule proteins. Methods Enzymology 1989; 169: 301-11.
    • (1989) Methods Enzymology , vol.169 , pp. 301-311
    • Sixma, J.J.1    Slot, J.-W.2    Geuze, H.J.3
  • 59
    • 0017599334 scopus 로고
    • Contractile proteins in platelet activation and contraction
    • Pollard TD, Fujiwara K, Handin R, Weiss G. Contractile proteins in platelet activation and contraction. Ann N Y Acad Sci 1977; 283: 218-36.
    • (1977) Ann N Y Acad Sci , vol.283 , pp. 218-236
    • Pollard, T.D.1    Fujiwara, K.2    Handin, R.3    Weiss, G.4
  • 60
    • 0018297817 scopus 로고
    • Interaction of microtubules and microfilaments in platelet contractile physiology
    • White JG, Gerrard JM. Interaction of microtubules and microfilaments in platelet contractile physiology. Methods Achiev Exp Pathol 1979; 9: 1-39.
    • (1979) Methods Achiev Exp Pathol , vol.9 , pp. 1-39
    • White, J.G.1    Gerrard, J.M.2
  • 61
    • 0021257306 scopus 로고
    • Platelet activation and cytoskeletal reorganization high voltage electron microscopic examination of intact and Triton-extracted whole mounts
    • Loftus JC, Choate J, Albrecht RM. Platelet activation and cytoskeletal reorganization high voltage electron microscopic examination of intact and Triton-extracted whole mounts. J Cell Biol 1989; 98: 2019-25.
    • (1989) J Cell Biol , vol.98 , pp. 2019-2025
    • Loftus, J.C.1    Choate, J.2    Albrecht, R.M.3
  • 62
    • 0034669992 scopus 로고    scopus 로고
    • Molecular mechanisms of platelet exocytosis: insights into the 'secrete' life of thrombocytes
    • Reed GL, Fitzgerald ML, Polga J. Molecular mechanisms of platelet exocytosis: insights into the 'secrete' life of thrombocytes. Blood 2000; 96: 3334-42.
    • (2000) Blood , vol.96 , pp. 3334-3342
    • Reed, G.L.1    Fitzgerald, M.L.2    Polga, J.3
  • 63
    • 0038785740 scopus 로고    scopus 로고
    • Molecular Basis of Platelet Granule Secretion
    • Flaumenhaft R. Molecular Basis of Platelet Granule Secretion. Arterioscler Thromb Vasc Biol 2003; 23: 1152-60.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 1152-1160
    • Flaumenhaft, R.1
  • 64
    • 55249092511 scopus 로고    scopus 로고
    • The Platelet Release Reaction: Just when you thought platelet secretion was simple
    • Ren Q, Ye S, Whiteheart SW. The Platelet Release Reaction: Just when you thought platelet secretion was simple. Curr Opin Hematol 2008; 15: 537-41.
    • (2008) Curr Opin Hematol , vol.15 , pp. 537-541
    • Ren, Q.1    Ye, S.2    Whiteheart, S.W.3
  • 65
    • 0021688767 scopus 로고
    • Centripetal myosin redistribution in thrombinstimulated platelets: relationship to platelet factor 4 secretion
    • Painter RG, Ginsberg MH. Centripetal myosin redistribution in thrombinstimulated platelets: relationship to platelet factor 4 secretion. Exp Cell Res 1984; 155: 198-212.
    • (1984) Exp Cell Res , vol.155 , pp. 198-212
    • Painter, R.G.1    Ginsberg, M.H.2
  • 66
    • 0018882072 scopus 로고
    • Differential effects of cytochalasin B on platelet release, aggregation and contractility: evidence against a contractile mechanism for the release of platelet granular contents
    • Kirkpatrick JP, McIntire LV, Moake JL, Cimo PL. Differential effects of cytochalasin B on platelet release, aggregation and contractility: evidence against a contractile mechanism for the release of platelet granular contents. Thromb Haemost 1980; 42: 1483-9.
    • (1980) Thromb Haemost , vol.42 , pp. 1483-1489
    • Kirkpatrick, J.P.1    McIntire, L.V.2    Moake, J.L.3    Cimo, P.L.4
  • 68
    • 0019939953 scopus 로고
    • Effects of a microtubule stabilizing agent on the response of platelets to vincristine
    • White JG, Rao GH. Effects of a microtubule stabilizing agent on the response of platelets to vincristine. Blood 1982; 60: 474-83.
    • (1982) Blood , vol.60 , pp. 474-483
    • White, J.G.1    Rao, G.H.2
  • 69
    • 0023856779 scopus 로고
    • Cytochalasin E enhances the protein kinase C-dependent process of secretion
    • Cox AC. Cytochalasin E enhances the protein kinase C-dependent process of secretion. Biochem Biophys Res Commun 1988; 150: 745-51.
    • (1988) Biochem Biophys Res Commun , vol.150 , pp. 745-751
    • Cox, A.C.1
  • 71
    • 18544374500 scopus 로고    scopus 로고
    • The actin cytoskeleton differentially regulates platelet α-granule and dense-granule secretion
    • Flaumenhaft R, Dilks JR, Rozenvayn N, Monahan-Earley RA, Feng D, Dvorak AM. The actin cytoskeleton differentially regulates platelet α-granule and dense-granule secretion. Blood 2005; 105: 3879-87.
    • (2005) Blood , vol.105 , pp. 3879-3887
    • Flaumenhaft, R.1    Dilks, J.R.2    Rozenvayn, N.3    Monahan-Earley, R.A.4    Feng, D.5    Dvorak, A.M.6
  • 72
    • 77956519683 scopus 로고    scopus 로고
    • Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis
    • Ren Q, Wimmer C, Chicka MC, Ye S, Ren Y, Hughson FM, Whiteheart SW. Munc13-4 is a limiting factor in the pathway required for platelet granule release and hemostasis. Blood 2010; 116: 869-77.
    • (2010) Blood , vol.116 , pp. 869-877
    • Ren, Q.1    Wimmer, C.2    Chicka, M.C.3    Ye, S.4    Ren, Y.5    Hughson, F.M.6    Whiteheart, S.W.7
  • 74
    • 34548823786 scopus 로고    scopus 로고
    • Evidence that differential packaging of the major platelet granule proteins von Willebrand factor and fibrinogen can support their differential release
    • Sehgal S, Storrie B. Evidence that differential packaging of the major platelet granule proteins von Willebrand factor and fibrinogen can support their differential release. J Thromb Haemost 2007; 5: 2009-16.
    • (2007) J Thromb Haemost , vol.5 , pp. 2009-2016
    • Sehgal, S.1    Storrie, B.2
  • 75
    • 38949178835 scopus 로고    scopus 로고
    • Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet {alpha} granules and differentially released
    • Italiano JE, Jr, Richardson JL, Patel-Hett S, Battinelli E, Zaslavsky A, Short S, Ryeom S, Folkman J, Klement GL. Angiogenesis is regulated by a novel mechanism: pro- and antiangiogenic proteins are organized into separate platelet {alpha} granules and differentially released. Blood 2008; 111: 1227-33.
    • (2008) Blood , vol.111 , pp. 1227-1233
    • Italiano Jr, J.E.1    Richardson, J.L.2    Patel-Hett, S.3    Battinelli, E.4    Zaslavsky, A.5    Short, S.6    Ryeom, S.7    Folkman, J.8    Klement, G.L.9
  • 76
    • 34247521816 scopus 로고    scopus 로고
    • Variable platelet response to aspirin and clopidogrel in atherothrombotic disease
    • Maree AO, Fitzgerald DJ. Variable platelet response to aspirin and clopidogrel in atherothrombotic disease. Circulation 2007; 115: 2196-207.
    • (2007) Circulation , vol.115 , pp. 2196-2207
    • Maree, A.O.1    Fitzgerald, D.J.2
  • 77
    • 0027161237 scopus 로고
    • Aspirin does not inhibit adenosine diphosphate-induced platelet a-granule release
    • Rinder CS, Student LA, Bonan JL, Rinder HM, Smith BI. Aspirin does not inhibit adenosine diphosphate-induced platelet a-granule release. Blood 1993; 82: 505- 12.
    • (1993) Blood , vol.82 , pp. 505-512
    • Rinder, C.S.1    Student, L.A.2    Bonan, J.L.3    Rinder, H.M.4    Smith, B.I.5
  • 78
    • 0348110562 scopus 로고    scopus 로고
    • Aspirin treatment does not attenuate platelet or leukocyte activation as monitored by whole blood flow cytometry
    • Li N, Hu H, Hjemdahl P. Aspirin treatment does not attenuate platelet or leukocyte activation as monitored by whole blood flow cytometry. Thromb Res 2003; 111: 165-70.
    • (2003) Thromb Res , vol.111 , pp. 165-170
    • Li, N.1    Hu, H.2    Hjemdahl, P.3
  • 79
    • 0033866804 scopus 로고    scopus 로고
    • Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: enhanced inhibitory effects of combination therapy
    • Moshfegh K, Redondo M, Julmy F, Wuillemin WA, Gebauer MU, Haeberli A, Meyer BJ. Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: enhanced inhibitory effects of combination therapy. J Am Coll Cardiol 2000; 36: 699-705.
    • (2000) J Am Coll Cardiol , vol.36 , pp. 699-705
    • Moshfegh, K.1    Redondo, M.2    Julmy, F.3    Wuillemin, W.A.4    Gebauer, M.U.5    Haeberli, A.6    Meyer, B.J.7
  • 80
    • 73949093109 scopus 로고    scopus 로고
    • Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization
    • Frelinger AL, Li Y, Linden MD, Barnard MR, Fox ML, Christie DJ, Furman MI, Michelson AD. Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. Circulation 2009; 120: 2586-96.
    • (2009) Circulation , vol.120 , pp. 2586-2596
    • Frelinger, A.L.1    Li, Y.2    Linden, M.D.3    Barnard, M.R.4    Fox, M.L.5    Christie, D.J.6    Furman, M.I.7    Michelson, A.D.8
  • 81
    • 33750700867 scopus 로고    scopus 로고
    • Newer pharmacotherapy in patients undergoing percutaneous coronary interventions: a guide for pharmacists and other health care professionals
    • Levine GN, Berger PB, Cohen DJ, Maree AO, Rosenfield K, Wiggins BS, Spinler SA. Newer pharmacotherapy in patients undergoing percutaneous coronary interventions: a guide for pharmacists and other health care professionals. Pharmacotherapy 2006; 26: 1537-56.
    • (2006) Pharmacotherapy , vol.26 , pp. 1537-1556
    • Levine, G.N.1    Berger, P.B.2    Cohen, D.J.3    Maree, A.O.4    Rosenfield, K.5    Wiggins, B.S.6    Spinler, S.A.7
  • 82
    • 0030590746 scopus 로고    scopus 로고
    • A randomized, blinded, trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE)
    • CAPRIE Steering Committee
    • CAPRIE Steering Committee. A randomized, blinded, trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE). Lancet 1996; 348: 1329-39.
    • (1996) Lancet , vol.348 , pp. 1329-1339
  • 84
    • 24644495673 scopus 로고    scopus 로고
    • Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study
    • Sabatine MS, Cannon CP, Gibson CM, Lopez-Sendon JL, Montalescot G, Theroux P, Lewis BS, Murphy SA, McCabe CH, Braunwald E. Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study. JAMA 2005; 294: 1224-32.
    • (2005) JAMA , vol.294 , pp. 1224-1232
    • Sabatine, M.S.1    Cannon, C.P.2    Gibson, C.M.3    Lopez-Sendon, J.L.4    Montalescot, G.5    Theroux, P.6    Lewis, B.S.7    Murphy, S.A.8    McCabe, C.H.9    Braunwald, E.10
  • 85
    • 3242770664 scopus 로고    scopus 로고
    • Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial
    • MATCH investigators
    • Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, Leys D, Matias-Guiu J, Rupprecht HJ, MATCH investigators. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet 2004; 364: 331-7.
    • (2004) Lancet , vol.364 , pp. 331-337
    • Diener, H.C.1    Bogousslavsky, J.2    Brass, L.M.3    Cimminiello, C.4    Csiba, L.5    Kaste, M.6    Leys, D.7    Matias-Guiu, J.8    Rupprecht, H.J.9
  • 89
    • 18044388905 scopus 로고    scopus 로고
    • Preclinical and clinical studies with selective reversible direct P2Y12 antagonists
    • Van Giezen JJJ, Humphries RG. Preclinical and clinical studies with selective reversible direct P2Y12 antagonists. Sem Thromb Hemost 2005; 31: 195-204.
    • (2005) Sem Thromb Hemost , vol.31 , pp. 195-204
    • Van Giezen, J.J.J.1    Humphries, R.G.2
  • 90
    • 77956885957 scopus 로고    scopus 로고
    • State of the art of new P2Y12 antagonists
    • Cattaneo M, Podda GM. State of the art of new P2Y12 antagonists. Intern Emerg Med 2010; 5: 385-91.
    • (2010) Intern Emerg Med , vol.5 , pp. 385-391
    • Cattaneo, M.1    Podda, G.M.2
  • 91
    • 0036714323 scopus 로고    scopus 로고
    • Inhibition of ADP-induced P-selectin expression and platelet-leukocyte conjugate formation by clopidogrel and the P2Y12 receptor antagonist AR-C69931MX but not aspirin
    • Storey RF, Judge HM, Wilcox RG, Heptinstall S. Inhibition of ADP-induced P-selectin expression and platelet-leukocyte conjugate formation by clopidogrel and the P2Y12 receptor antagonist AR-C69931MX but not aspirin. Thromb Haemost 2002; 88: 488-94.
    • (2002) Thromb Haemost , vol.88 , pp. 488-494
    • Storey, R.F.1    Judge, H.M.2    Wilcox, R.G.3    Heptinstall, S.4
  • 93
    • 65649099288 scopus 로고    scopus 로고
    • Effect of long-term clopidogrel treatment on platelet function and inflammation in patients undergoing coronary arterial stenting
    • Antonino MJ, Mahla E, Bliden KP, Tantry US, Gurbel PA. Effect of long-term clopidogrel treatment on platelet function and inflammation in patients undergoing coronary arterial stenting. Am J Cardiol 2009; 103: 1546-50.
    • (2009) Am J Cardiol , vol.103 , pp. 1546-1550
    • Antonino, M.J.1    Mahla, E.2    Bliden, K.P.3    Tantry, U.S.4    Gurbel, P.A.5
  • 94
    • 33845606632 scopus 로고    scopus 로고
    • Activation of platelet function through G protein-coupled receptors
    • Offermanns S. Activation of platelet function through G protein-coupled receptors. Circ Res 2006; 99: 1293-304.
    • (2006) Circ Res , vol.99 , pp. 1293-1304
    • Offermanns, S.1
  • 95
    • 0030987070 scopus 로고    scopus 로고
    • Regulation of protein kinase C
    • Newton AC. Regulation of protein kinase C. Curr Opin Cell Biol 1997; 9: 161-67.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 161-167
    • Newton, A.C.1
  • 96
    • 0032104245 scopus 로고    scopus 로고
    • The extended protein kinase C superfamily
    • Mellor H, Parker PJ. The extended protein kinase C superfamily. Biochem J 1998; 332: 281-92.
    • (1998) Biochem J , vol.332 , pp. 281-292
    • Mellor, H.1    Parker, P.J.2
  • 97
    • 0032828089 scopus 로고    scopus 로고
    • Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors
    • Paul BZ, Jin J, Kunapuli SP. Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors. J Bio Chem 1999; 274: 29108-14.
    • (1999) J Bio Chem , vol.274 , pp. 29108-29114
    • Paul, B.Z.1    Jin, J.2    Kunapuli, S.P.3
  • 98
    • 0036905073 scopus 로고    scopus 로고
    • Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation
    • Quinton TM, Kim S, Dangelmaier C, Dorsam RT, Jin J, Daniel JL, Kunapuli SP. Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation. Biochem J 2002; 368: 535-53.
    • (2002) Biochem J , vol.368 , pp. 535-553
    • Quinton, T.M.1    Kim, S.2    Dangelmaier, C.3    Dorsam, R.T.4    Jin, J.5    Daniel, J.L.6    Kunapuli, S.P.7
  • 99
    • 0034682816 scopus 로고    scopus 로고
    • Protein kinase C phosphorylation of syntaxin 4 in thrombin-activated human platelets
    • Chung SH, Polgar J, Reed GL. Protein kinase C phosphorylation of syntaxin 4 in thrombin-activated human platelets. J Biol Chem 2000; 275: 25286-91.
    • (2000) J Biol Chem , vol.275 , pp. 25286-25291
    • Chung, S.H.1    Polgar, J.2    Reed, G.L.3
  • 101
    • 1642535447 scopus 로고    scopus 로고
    • Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets
    • Murugappan S, Tuluc F, Dorsam RT, Shankar H, Kunapuli SP. Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets. J Biol Chem 2004; 279: 2360-7.
    • (2004) J Biol Chem , vol.279 , pp. 2360-2367
    • Murugappan, S.1    Tuluc, F.2    Dorsam, R.T.3    Shankar, H.4    Kunapuli, S.P.5
  • 103
    • 0042733338 scopus 로고    scopus 로고
    • Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases
    • Li Z, Zhang G, Le Breton GC, Gao X, Malik AB, Du X. Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. J Biol Chem 2003; 278: 30725-31.
    • (2003) J Biol Chem , vol.278 , pp. 30725-30731
    • Li, Z.1    Zhang, G.2    Le Breton, G.C.3    Gao, X.4    Malik, A.B.5    Du, X.6
  • 104
    • 0032828089 scopus 로고    scopus 로고
    • Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors
    • Paul BZ, Jin J, Kunapuli SP. Molecular mechanism of thromboxane A(2)-induced platelet aggregation. Essential role for p2t(ac) and alpha(2a) receptors. J Biol Chem 1999; 274: 29108-14.
    • (1999) J Biol Chem , vol.274 , pp. 29108-29114
    • Paul, B.Z.1    Jin, J.2    Kunapuli, S.P.3
  • 107
    • 0022379083 scopus 로고
    • Relationship between cytosplasmic free calcium and myosin light chain phosphorylation in intact platelets
    • Hallam TJ, Daniel JL, Kendrick Jones J, Rink TJ. Relationship between cytosplasmic free calcium and myosin light chain phosphorylation in intact platelets. Biochem J 1985; 232: 373-7.
    • (1985) Biochem J , vol.232 , pp. 373-377
    • Hallam, T.J.1    Daniel, J.L.2    Kendrick Jones, J.3    Rink, T.J.4
  • 108
    • 0028303913 scopus 로고
    • cAMP and cGMP-dependent protein kinase [hosphorylation sites of the focal vasodilator-stimulated phosphoprotein (VASP) in vitro in intact human plateltes
    • Butt E, Abel K, Krieger M, Palm D, Hoppe V, Hoppe J, Walter J. cAMP and cGMP-dependent protein kinase [hosphorylation sites of the focal vasodilator-stimulated phosphoprotein (VASP) in vitro in intact human plateltes. J Biol Chem 1994; 269: 14509-17.
    • (1994) J Biol Chem , vol.269 , pp. 14509-14517
    • Butt, E.1    Abel, K.2    Krieger, M.3    Palm, D.4    Hoppe, V.5    Hoppe, J.6    Walter, J.7
  • 109
    • 5644249326 scopus 로고    scopus 로고
    • A platelet secretion pathway mediated by cGMP-dependent protein kinase
    • Li Z, Zhang G, Marjanovic JA, Ruan C, Du X. A platelet secretion pathway mediated by cGMP-dependent protein kinase. J Biol Chem 2004; 279: 42469-75.
    • (2004) J Biol Chem , vol.279 , pp. 42469-42475
    • Li, Z.1    Zhang, G.2    Marjanovic, J.A.3    Ruan, C.4    Du, X.5
  • 111
    • 0014829353 scopus 로고
    • Uptake, metabolism and release of (3H)-adrenalin by human platelets
    • Born GV, Smith JB. Uptake, metabolism and release of (3H)-adrenalin by human platelets. Br J Pharmacol 1970; 39: 765-78.
    • (1970) Br J Pharmacol , vol.39 , pp. 765-778
    • Born, G.V.1    Smith, J.B.2
  • 112
    • 0030605978 scopus 로고    scopus 로고
    • Evidence for separate serotonin and catecholamine compartments in human platelets
    • Smith CC. Evidence for separate serotonin and catecholamine compartments in human platelets. Biochim Biophys Acta 1996; 1291: 1-4.
    • (1996) Biochim Biophys Acta , vol.1291 , pp. 1-4
    • Smith, C.C.1
  • 113
    • 0018163875 scopus 로고
    • Platelet function is essential in thrmbocythemia: decreased epinephrine responsiveness of platelets associated with a deficiency in alpha-adrenergic receptors
    • Kaywin P, McDonough M, Insel PA, Shattil SJ. Platelet function is essential in thrmbocythemia: decreased epinephrine responsiveness of platelets associated with a deficiency in alpha-adrenergic receptors. N Engl J Med 1978; 299: 505-9.
    • (1978) N Engl J Med , vol.299 , pp. 505-509
    • Kaywin, P.1    McDonough, M.2    Insel, P.A.3    Shattil, S.J.4
  • 115
    • 0027955746 scopus 로고
    • Epinephrine sensitizes human platelets in vivo and in vitro as studied by fibrinogen binding and P-selectin expression
    • Hjemdahl P, Chronos NA, Wilson DJ, Bouloux P, Goodall AH. Epinephrine sensitizes human platelets in vivo and in vitro as studied by fibrinogen binding and P-selectin expression. Arterioscler Thromb Vasc Biol 1994; 14: 77-84.
    • (1994) Arterioscler Thromb Vasc Biol , vol.14 , pp. 77-84
    • Hjemdahl, P.1    Chronos, N.A.2    Wilson, D.J.3    Bouloux, P.4    Goodall, A.H.5
  • 117
    • 77954791521 scopus 로고    scopus 로고
    • The role of prostanoid receptors in mediating the effects of PGE(2) on human platelet function
    • Iyú D, Glenn JR, White AE, Johnson AJ, Fox SC, Heptinstall S. The role of prostanoid receptors in mediating the effects of PGE(2) on human platelet function. Platelets 2010; 21: 329-42.
    • (2010) Platelets , vol.21 , pp. 329-342
    • Iyú, D.1    Glenn, J.R.2    White, A.E.3    Johnson, A.J.4    Fox, S.C.5    Heptinstall, S.6
  • 119
    • 0035806894 scopus 로고    scopus 로고
    • Increased bleeding tendency and decrease susceptibility to thromboembolism in mice lacking the prostaglandin E2 receptor subtype EP(3)
    • Ma H, Hara A, Xiao CY, Okada Y, Takahata O, Nakaya K, Sugimoto Y, Ichikawa A, Narumiya S, Ushikubi F. Increased bleeding tendency and decrease susceptibility to thromboembolism in mice lacking the prostaglandin E2 receptor subtype EP(3). Circulation 2001; 104: 1176-80.
    • (2001) Circulation , vol.104 , pp. 1176-1180
    • Ma, H.1    Hara, A.2    Xiao, C.Y.3    Okada, Y.4    Takahata, O.5    Nakaya, K.6    Sugimoto, Y.7    Ichikawa, A.8    Narumiya, S.9    Ushikubi, F.10
  • 121
    • 0034617072 scopus 로고    scopus 로고
    • B2-adrenoreceptors activate nitric oxide synthase in human platelets
    • Queen LR, Xu B, Horinouchi K, Fisher I, Ferro A. B2-adrenoreceptors activate nitric oxide synthase in human platelets. Circ Res 2000; 87: 39-44.
    • (2000) Circ Res , vol.87 , pp. 39-44
    • Queen, L.R.1    Xu, B.2    Horinouchi, K.3    Fisher, I.4    Ferro, A.5
  • 123
    • 34547770795 scopus 로고    scopus 로고
    • Age decreases nitric oxide synthesis and responsiveness in human platelets and increases formation of monocyte-platelet aggregates
    • Goubareva I, Gkaliagkousi E, Shah A, Queen L, Ferro A. Age decreases nitric oxide synthesis and responsiveness in human platelets and increases formation of monocyte-platelet aggregates. Cardiovasc Res 2007; 75: 793-802.
    • (2007) Cardiovasc Res , vol.75 , pp. 793-802
    • Goubareva, I.1    Gkaliagkousi, E.2    Shah, A.3    Queen, L.4    Ferro, A.5
  • 124
    • 0037428145 scopus 로고    scopus 로고
    • A stimulatory role for cGMP-dependent protein kinase in platelet activation
    • Li Z, Xi X, Gu M, Feil R, Ye RD, Eigenthaler M, Hofman F, Du X. A stimulatory role for cGMP-dependent protein kinase in platelet activation. Cell 2003; 112: 77-86.
    • (2003) Cell , vol.112 , pp. 77-86
    • Li, Z.1    Xi, X.2    Gu, M.3    Feil, R.4    Ye, R.D.5    Eigenthaler, M.6    Hofman, F.7    Du, X.8
  • 125
    • 0038142355 scopus 로고    scopus 로고
    • A predominant role for cAMP-dependent protein kinase in cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans
    • Li Z, Ajdic J, Eigenthaler M, Du X. A predominant role for cAMP-dependent protein kinase in cGMP-induced phosphorylation of vasodilator-stimulated phosphoprotein and platelet inhibition in humans. Blood 2003; 101: 4423-9.
    • (2003) Blood , vol.101 , pp. 4423-4429
    • Li, Z.1    Ajdic, J.2    Eigenthaler, M.3    Du, X.4
  • 126
    • 0035868374 scopus 로고    scopus 로고
    • Inhibition of platelet aggregation and the release of P-selectin from platelets by cilostazol
    • Kariyazono H, Nakamra K, Shinkawa T, Yamaguchi T, Sakata R, Yamada K. Inhibition of platelet aggregation and the release of P-selectin from platelets by cilostazol. Thrombosis Res 2001; 101: 445-53.
    • (2001) Thrombosis Res , vol.101 , pp. 445-453
    • Kariyazono, H.1    Nakamra, K.2    Shinkawa, T.3    Yamaguchi, T.4    Sakata, R.5    Yamada, K.6
  • 127
    • 3843061338 scopus 로고    scopus 로고
    • Cilostazol inhibits platelet leukocyte interaction by suppression of platelet activation
    • Ito H, Miyakoda G, Mori T. Cilostazol inhibits platelet leukocyte interaction by suppression of platelet activation. Platelets 2004; 15: 293-301.
    • (2004) Platelets , vol.15 , pp. 293-301
    • Ito, H.1    Miyakoda, G.2    Mori, T.3
  • 128
    • 34548633702 scopus 로고    scopus 로고
    • Comparison of triple versus dual anti-platelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial)
    • Lee SW, Park SW, Kim YH. Comparison of triple versus dual anti-platelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial). Am J Cardiol 2007; 100: 1103-8.
    • (2007) Am J Cardiol , vol.100 , pp. 1103-1108
    • Lee, S.W.1    Park, S.W.2    Kim, Y.H.3
  • 129
    • 0041967519 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin
    • Serebruany VL, Glassman AH, Malinin AI, Atar D, Sane DC, Oshrine BR, Ferguson JJ, O'Connor CM. Selective serotonin reuptake inhibitors yield additional antiplatelet protection in patients with congestive heart failure treated with antecedent aspirin. Eur J Heart Fail 2003; 5: 517-21.
    • (2003) Eur J Heart Fail , vol.5 , pp. 517-521
    • Serebruany, V.L.1    Glassman, A.H.2    Malinin, A.I.3    Atar, D.4    Sane, D.C.5    Oshrine, B.R.6    Ferguson, J.J.7    O'Connor, C.M.8
  • 131
    • 0031681434 scopus 로고    scopus 로고
    • Novel therapeutic approaches beyond the serotonin receptor
    • Duman RS. Novel therapeutic approaches beyond the serotonin receptor. Biol Psychiatry 1998; 44: 324-35.
    • (1998) Biol Psychiatry , vol.44 , pp. 324-335
    • Duman, R.S.1
  • 132
    • 39749181656 scopus 로고    scopus 로고
    • Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents
    • Xu Q, Yi LT, Pan Y, Wang X, Li YC, Li JM, Wang CP, Kong LD. Antidepressant-like effects of the mixture of honokiol and magnolol from the barks of Magnolia officinalis in stressed rodents. Prog Neuropsychopharmacol Biol Psychiatry 2008; 32: 715-25.
    • (2008) Prog Neuropsychopharmacol Biol Psychiatry , vol.32 , pp. 715-725
    • Xu, Q.1    Yi, L.T.2    Pan, Y.3    Wang, X.4    Li, Y.C.5    Li, J.M.6    Wang, C.P.7    Kong, L.D.8
  • 133
    • 62849090443 scopus 로고    scopus 로고
    • Antidepressant-like effects of curcumin on serotonergic receptor-coupled AC-cAMP pathway in chronic unpredictable mild stress of rats
    • Li YC, Wang FM, Pan Y, Qiang LQ, Cheng G, Zhang WY, Kong LD. Antidepressant-like effects of curcumin on serotonergic receptor-coupled AC-cAMP pathway in chronic unpredictable mild stress of rats. Prog Neuropsychopharmacol Biol Psychiatry 2009; 33: 435-4.
    • (2009) Prog Neuropsychopharmacol Biol Psychiatry , vol.33 , pp. 435-434
    • Li, Y.C.1    Wang, F.M.2    Pan, Y.3    Qiang, L.Q.4    Cheng, G.5    Zhang, W.Y.6    Kong, L.D.7
  • 134
    • 77957963730 scopus 로고    scopus 로고
    • Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes
    • CD002130.
    • Bosch X, Marrugat J, Sanchis J. Platelet glycoprotein IIb/IIIa blockers during percutaneous coronary intervention and as the initial medical treatment of non-ST segment elevation acute coronary syndromes. Cochrane Database Syst Rev 2010; (9): CD002130.
    • (2010) Cochrane Database Syst Rev , Issue.9
    • Bosch, X.1    Marrugat, J.2    Sanchis, J.3
  • 135
    • 0034604123 scopus 로고    scopus 로고
    • Long-term treatment with a platelet glycoprotein-receptor antagonist after percutaneous coronary revascularization. EXCITE Trial Investigators. Evaluation of Oral Xemilofiban in Controlling Thrombotic Events
    • O'Neill WW, Serruys P, Knudtson M, van Es GA, Timmis GC, van der Zwaan C, Kleiman J, Gong J, Roecker EB, Dreiling R, Alexander J, Anders R. Long-term treatment with a platelet glycoprotein-receptor antagonist after percutaneous coronary revascularization. EXCITE Trial Investigators. Evaluation of Oral Xemilofiban in Controlling Thrombotic Events. N Engl J Med 2000; 342: 1316-24.
    • (2000) N Engl J Med , vol.342 , pp. 1316-1324
    • O'Neill, W.W.1    Serruys, P.2    Knudtson, M.3    van Es, G.A.4    Timmis, G.C.5    van der Zwaan, C.6    Kleiman, J.7    Gong, J.8    Roecker, E.B.9    Dreiling, R.10    Alexander, J.11    Anders, R.12
  • 136
    • 0034728088 scopus 로고    scopus 로고
    • Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: a randomised trial. The SYMPHONY Investigators. Sibrafiban versus Aspirin to Yield Maximum Protection from Ischemic Heart Events Post-acute Coronary Syndromes
    • Comparison of sibrafiban with aspirin for prevention of cardiovascular events after acute coronary syndromes: a randomised trial. The SYMPHONY Investigators. Sibrafiban versus Aspirin to Yield Maximum Protection from Ischemic Heart Events Post-acute Coronary Syndromes. Lancet 2000; 355: 337-45.
    • (2000) Lancet , vol.355 , pp. 337-345
  • 137
    • 0035799340 scopus 로고    scopus 로고
    • Randomized trial of aspirin, sibrafiban, or both for secondary prevention after acute coronary syndromes
    • SYMPHONY II Investigators
    • SYMPHONY II Investigators. Randomized trial of aspirin, sibrafiban, or both for secondary prevention after acute coronary syndromes. Circulation 2001; 103: 1727-33.
    • (2001) Circulation , vol.103 , pp. 1727-1733
  • 138
  • 139
    • 0038495927 scopus 로고    scopus 로고
    • Targeting of the collagen-binding site on glycoprotein VI is not essential for in vivo depletion of the receptor
    • Schulte V, Rabie T, Prostredna M, Aktas B, Gruner S, Nieswandt B. Targeting of the collagen-binding site on glycoprotein VI is not essential for in vivo depletion of the receptor. Blood 2003; 101: 3948-52.
    • (2003) Blood , vol.101 , pp. 3948-3952
    • Schulte, V.1    Rabie, T.2    Prostredna, M.3    Aktas, B.4    Gruner, S.5    Nieswandt, B.6
  • 140
    • 9144271618 scopus 로고    scopus 로고
    • IJsseldijk MJ, De Groot PG, Watkins NA, Farndale RW, Ouwehand WH. Identification of the primary collagen binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody
    • Smethurst PA, Joutsi-Korhonen L, O'Connor MN, Wilson E, Jennings NS, Garner SF, Zhang Y, Knight CG, Dafforn TR, Buckle A. IJsseldijk MJ, De Groot PG, Watkins NA, Farndale RW, Ouwehand WH. Identification of the primary collagen binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody. Blood 2004; 103: 903-11.
    • (2004) Blood , vol.103 , pp. 903-911
    • Smethurst, P.A.1    Joutsi-Korhonen, L.2    O'Connor, M.N.3    Wilson, E.4    Jennings, N.S.5    Garner, S.F.6    Zhang, Y.7    Knight, C.G.8    Dafforn, T.R.9    Buckle, A.10
  • 143
    • 40649107818 scopus 로고    scopus 로고
    • Aptamers as candidate therapeutics for cardiovascular indications
    • Keefe AD, Shaub RG. Aptamers as candidate therapeutics for cardiovascular indications. Curr Opin Pharm 2008; 8: 147-52.
    • (2008) Curr Opin Pharm , vol.8 , pp. 147-152
    • Keefe, A.D.1    Shaub, R.G.2
  • 144
    • 0028641293 scopus 로고
    • Abolition of cyclic flow variations in stenosed, endothelium-injured coronary arteries in nonhuman primates with a peptide fragment (VCL) derived from human plasma von Willebrand factor-glycoprotein Ib binding domain
    • McGhie AI, McNatt J, Ezov N, Cui K, Lowell K, Mower LK, Hagay Y, Buja LM, Garfinkel LI, Gorecki M, Willerson JT. Abolition of cyclic flow variations in stenosed, endothelium-injured coronary arteries in nonhuman primates with a peptide fragment (VCL) derived from human plasma von Willebrand factor-glycoprotein Ib binding domain. Circulation 1994; 90: 2976-81.
    • (1994) Circulation , vol.90 , pp. 2976-2981
    • McGhie, A.I.1    McNatt, J.2    Ezov, N.3    Cui, K.4    Lowell, K.5    Mower, L.K.6    Hagay, Y.7    Buja, L.M.8    Garfinkel, L.I.9    Gorecki, M.10    Willerson, J.T.11
  • 147
    • 0036308072 scopus 로고    scopus 로고
    • Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins
    • Wang L, Brown JR, Varki A, Esko JD. Heparin's anti-inflammatory effects require glucosamine 6-O-sulfation and are mediated by blockade of L- and P-selectins. J Clin Invest 2002; 110: 127-36.
    • (2002) J Clin Invest , vol.110 , pp. 127-136
    • Wang, L.1    Brown, J.R.2    Varki, A.3    Esko, J.D.4
  • 148
    • 34547669348 scopus 로고    scopus 로고
    • Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions
    • Oostingh GJ, Pozgajova M, Ludwig RJ, Krahn T, Boehncke WH, Nieswandt B, Schön MP. Diminished thrombus formation and alleviation of myocardial infarction and reperfusion injury through antibody- or small-molecule-mediated inhibition of selectin-dependent platelet functions. Haematologica 2007; 92: 502-12.
    • (2007) Haematologica , vol.92 , pp. 502-512
    • Oostingh, G.J.1    Pozgajova, M.2    Ludwig, R.J.3    Krahn, T.4    Boehncke, W.H.5    Nieswandt, B.6    Schön, M.P.7
  • 150
    • 0033605120 scopus 로고    scopus 로고
    • Inhibition of L-selectin-mediated leukocyte rolling by synthetic glycoprotein mimics
    • Sanders WJ, Gordon EJ, Dwir O, Beck PJ, Alon R, Kiessling LL. Inhibition of L-selectin-mediated leukocyte rolling by synthetic glycoprotein mimics. J Biol Chem 1999; 274: 5271-8.
    • (1999) J Biol Chem , vol.274 , pp. 5271-5278
    • Sanders, W.J.1    Gordon, E.J.2    Dwir, O.3    Beck, P.J.4    Alon, R.5    Kiessling, L.L.6
  • 151
    • 0032959372 scopus 로고    scopus 로고
    • Recombinant soluble P-selectin glycoprotein ligand-1 protects against myocardial ischemic reperfusion injury in cats
    • Hayward R, Campbell B, Shin YK, Scalia R, Lefer AM. Recombinant soluble P-selectin glycoprotein ligand-1 protects against myocardial ischemic reperfusion injury in cats. Cardiovasc Res 1999; 41: 65-76.
    • (1999) Cardiovasc Res , vol.41 , pp. 65-76
    • Hayward, R.1    Campbell, B.2    Shin, Y.K.3    Scalia, R.4    Lefer, A.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.