Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: Enhanced inhibitory effects of combination therapy

Journal of the American College of Cardiology

Volumn 36, Issue 3, 2000, Pages 699-705

  Moshfegh, Khatereh ^a   Redondo, Maurice ^a   Julmy, Friedgard ^a   Wuillemin, Walter A ^a   Gebauer, Mathias U ^a   Haeberli, André ^a   Meyer, Beat J ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; CD63 ANTIGEN; CLOPIDOGREL; PADGEM PROTEIN;

ACUTE HEART INFARCTION; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG POTENTIATION; HEART INFARCTION; HUMAN; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; UNSTABLE ANGINA PECTORIS;

ADENOSINE DIPHOSPHATE; ADULT; AGED; ANTIGENS, CD; ASPIRIN; BLOOD; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG THERAPY, COMBINATION; HUMANS; MIDDLE AGED; MYOCARDIAL INFARCTION; P-SELECTIN; PEPTIDE FRAGMENTS; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET MEMBRANE GLYCOPROTEINS; PROSPECTIVE STUDIES; PROTEIN-TYROSINE-PHOSPHATASE; TICLOPIDINE;

EID: 0033866804     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(00)00817-2     Document Type: Article

References (32)

1. Collaborative overview of randomized trials of antiplatelet therapy - I: Prevention of death, myocardial infarction and stroke by prolonged antiplatelet therapy in various categories of patients
2. Prior aspirin use predicts worse outcomes in patients with non-ST elevation acute coronary syndromes
3. Differential suppression of thromboxane biosynthesis by indobufen and aspirin in patients with unstable angina
4. Platelet GPIIb-IIIa blockers
5. A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary artery stents
6. A clinical trial comparing three antithrombotic-drug regimens after coronary artery stenting
7. Randomized multicenter comparison of conventional anticoagulation versus antiplatelet therapy in unplanned and elective coronary stenting. The full anticoagulation versus aspirin and ticlopidine (FANTASTIC) study
8. Randomized evaluation of anticoagulation versus antiplatelet therapy after coronary stent implantation in high-risk patients. The multicenter aspirin and ticlopidine trial after intracoronary stenting (MATTIS)
9. Effectiveness of clopidogrel and aspirin versus ticlopidine and aspirin in preventing stent thrombosis after coronary stent implantation
10. A randomized, blinded, trial of clopidogrel versus aspirin in patients at risk of ischemic events (CAPRIE)
11. Clopidogrel inhibition of stent, graft and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates
12. The antiaggregating and antithrombotic activity of clopidogrel is potentiated by aspirin in several experimental models in the rabbit
13. Effects of clopidogrel, aspirin and combined therapy in a porcine ex vivo model of high-shear induced stent thrombosis
14. Biochemical and pharmacological properties of clopidogrel: A new ADP receptor antagonist
15. Flow cytometry: A clinical test of platelet function
16. Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: An explanation for the thrombotic complications of heparin-induced thrombocytopenia
17. Mechanisms of cerebrovascular events as assessed by procoagulant activity, cerebral microemboli and platelet microparticles in patients with prosthetic heart valves
18. Platelet activation by thrombin can be directly measured in whole blood through the use of the peptide GPRP and flow cytometry: Methods and clinical applications
19. Flow cytometric analysis of platelet activation by different collagen types present in the vessel wall
20. Early potent antithrombotic effect with combined aspirin and a loading dose of clopidogrel on experimental arterial thrombogenesis in humans
21. Single dose clopidogrel inhibition of platelet adenosine receptor function in patients with atherosclerotic coronary artery disease
22. Platelet antiaggregating activity and tolerance of clopidogrel in atherosclerotic patients
23. Comparison of anti-platelet effects of aspirin, ticlopidine or their combination after stent implantation
24. Platelet function in acute myocardial infarction treated with direct angioplasty
25. Platelet membrane activation markers are predictive for increased risk of acute ischemic events after PTCA
26. Platelet activation and coronary stent implantation. Effect of antithrombotic therapy
27. Platelet activation in patients after an acute coronary syndrome: Results from the TIMI-12 Trial
28. Dissolution of mural thrombus by specific thrombin inhibition with r-hirudin: Comparison with heparin and aspirin
29. Antiplatelet drugs. A comparative review
30. Clopidogrel as adjunctive antiplatelet therapy during coronary stenting
31. Clopidogrel versus ticlopidine after intracoronary stent placement
32. Meeting highlights. Highlights of the 48th Scientific Sessions of the American College of Cardiology