-
1
-
-
0033760391
-
2T receptor in amplification of human platelet activation, aggregation, secretion and procoagulant activity
-
2T receptor in amplification of human platelet activation, aggregation, secretion and procoagulant activity. Br J Haematol. 2000;110:925-934.
-
(2000)
Br J Haematol
, vol.110
, pp. 925-934
-
-
Storey, R.F.1
Sanderson, H.M.2
May, J.A.3
White, A.E.4
Cameron, K.E.5
Heptinstall, S.6
-
3
-
-
33750069428
-
Nu-cleotide receptor signaling in platelets
-
Kahner BN, Shankar H, Murugappan S, Prasad GL, Kunapuli SP. Nu-cleotide receptor signaling in platelets. J Thromb Haemost. 2006;4: 2317-2326.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 2317-2326
-
-
Kahner, B.N.1
Shankar, H.2
Murugappan, S.3
Prasad, G.L.4
Kunapuli, S.P.5
-
4
-
-
42249102617
-
P2 receptors, platelet function and pharmacological implications
-
Gachet C. P2 receptors, platelet function and pharmacological implications. Thromb Haemostasis. 2008;99:466-472.
-
(2008)
Thromb Haemostasis
, vol.99
, pp. 466-472
-
-
Gachet, C.1
-
7
-
-
77749289646
-
12 receptor antagonist pharmacoki-netics and pharmacodynamics: A foundation for distinguishing mechanisms of bleeding and anticipated risk for platelet-directed therapies
-
12 receptor antagonist pharmacoki-netics and pharmacodynamics: a foundation for distinguishing mechanisms of bleeding and anticipated risk for platelet-directed therapies. Thromb Haemostasis. 2010;103:535-544.
-
(2010)
Thromb Haemostasis
, vol.103
, pp. 535-544
-
-
Becker, R.C.1
Gurbel, P.A.2
-
8
-
-
75949128633
-
Antiplatelet therapies for the treatment of cardiovascular disease
-
Michelson AD. Antiplatelet therapies for the treatment of cardiovascular disease. Nat Rev Drug Discov. 2010;9:154-169.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 154-169
-
-
Michelson, A.D.1
-
9
-
-
0024455052
-
Metabolism of adenine nucleotides in human blood
-
Coade SB, Pearson JD. Metabolism of adenine nucleotides in human blood. Circ Res. 1989;65:531-537.
-
(1989)
Circ Res
, vol.65
, pp. 531-537
-
-
Coade, S.B.1
Pearson, J.D.2
-
10
-
-
0033766981
-
Extracellular metabolism of ATP and other nucleotides
-
Zimmermann H. Extracellular metabolism of ATP and other nucleotides. Naunyn Schmiedeberg's Arch Pharmacol. 2000;362:299-309.
-
(2000)
Naunyn Schmiedeberg's Arch Pharmacol
, vol.362
, pp. 299-309
-
-
Zimmermann, H.1
-
11
-
-
28444462118
-
Adenine nucleotide metabolism in human blood-important roles for leukocytes and eryth-rocytes
-
Heptinstall S, Johnson A, Glenn JR, White AE. Adenine nucleotide metabolism in human blood-important roles for leukocytes and eryth-rocytes. J Thromb Haemost. 2005;3:2331-2339.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 2331-2339
-
-
Heptinstall, S.1
Johnson, A.2
Glenn, J.R.3
White, A.E.4
-
12
-
-
0029018128
-
Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryp-tamine release in human platelets
-
Cooper JA, Hill SJ, Alexander SPH, Rubin PC, Horn EH. Adenosine receptor-induced cyclic AMP generation and inhibition of 5-hydroxytryp-tamine release in human platelets. Br J Clin Pharmacol. 1995;40:43-50.
-
(1995)
Br J Clin Pharmacol
, vol.40
, pp. 43-50
-
-
Cooper, J.A.1
Hill, S.J.2
Alexander, S.P.H.3
Rubin, P.C.4
Horn, E.H.5
-
13
-
-
42649146229
-
Gene expression profiling for the identification of G-protein coupled receptors in human platelets
-
Amisten S, Braun OO, Bengtsson A, Erlinge D. Gene expression profiling for the identification of G-protein coupled receptors in human platelets. Thromb Res. 2008;122:47-57.
-
(2008)
Thromb Res
, vol.122
, pp. 47-57
-
-
Amisten, S.1
Braun, O.O.2
Bengtsson, A.3
Erlinge, D.4
-
14
-
-
77952703085
-
A new role for the A2b adenosine receptor regulating platelet function
-
Yang D, Chen H, Koupenova M, Carroll SH, Eliades A, Freedman JE, Toselli P, Ravid K. A new role for the A2b adenosine receptor regulating platelet function. J Throm Haemost. 2010;8:817-827.
-
(2010)
J Throm Haemost.
, vol.8
, pp. 817-827
-
-
Yang, D.1
Chen, H.2
Koupenova, M.3
Carroll, S.H.4
Eliades, A.5
Freedman, J.E.6
Toselli, P.7
Ravid, K.8
-
15
-
-
0025937656
-
Endogenous adenosine inhibits platelet aggregation during myocardial ischemia in dogs
-
Kitakaze M, Hori M, Sato H, Takashima S, Inoue M, Kitabatake A, Kamada T. Endogenous adenosine inhibits platelet aggregation during myocardial ischemia in dogs. Circ Res. 1991;69:1402-1408.
-
(1991)
Circ Res
, vol.69
, pp. 1402-1408
-
-
Kitakaze, M.1
Hori, M.2
Sato, H.3
Takashima, S.4
Inoue, M.5
Kitabatake, A.6
Kamada, T.7
-
16
-
-
0030945186
-
The endothelial cells Ecto-ADPase responsible for inhibition of platelet function is CD39
-
Marcus AJ, Broekman MJ, Drosopoulos JHF, Islam N, Alyonycheva TN, Saffer LB, Hajjar KA, Posnett DN, Schoenborn MA, Schooley KA, Gayle RB, Maliszewski CR. The endothelial cells Ecto-ADPase responsible for inhibition of platelet function is CD39. J Clin Invest. 1997;99:1351-1360.
-
(1997)
J Clin Invest
, vol.99
, pp. 1351-1360
-
-
Marcus, A.J.1
Broekman, M.J.2
Jhf, D.3
Islam, N.4
Alyonycheva, T.N.5
Saffer, L.B.6
Hajjar, K.A.7
Posnett, D.N.8
Schoenborn, M.A.9
Schooley, K.A.10
Gayle, R.B.11
Maliszewski, C.R.12
-
17
-
-
0035146418
-
Thromboregulation by endothelial cells: Significance for occlusive vascular disesases
-
Marcus AJ, Broekman MJ, Drosopoulos JHF, Pinsky DJ, Islam N, Gayle RB III, Maliszewski CR. Thromboregulation by endothelial cells: significance for occlusive vascular disesases. Arterioscler Throm Vasc Biol. 2001;21:178-182.
-
(2001)
Arterioscler Throm Vasc Biol
, vol.21
, pp. 178-182
-
-
Marcus, A.J.1
Broekman, M.J.2
Drosopoulos, J.H.F.3
Pinsky, D.J.4
Islam, N.5
Gayle Iii, R.B.6
Maliszewski, C.R.7
-
18
-
-
6344283049
-
Targeted disruption of cd73/ecto-5'-nucelotidase alters thromboregulation and augments vascular inflammatory response
-
Koszalka P, Ozüyaman B, Huo Y, Zernecke A, Flogel U, Braun N, Buchheiser A, Decking UK, Smith ML, Sevigny J, Gear A, Weber AA, Molojavyi A, Ding Z, Weber C, Ley K, Zimmermann H, Godecke A, Schrader J. Targeted disruption of cd73/ecto-5'-nucelotidase alters thromboregulation and augments vascular inflammatory response. Circ Res. 2004;95:814-821.
-
(2004)
Circ Res
, vol.95
, pp. 814-821
-
-
Koszalka, P.1
Ozüyaman, B.2
Huo, Y.3
Zernecke, A.4
Flogel, U.5
Braun, N.6
Buchheiser, A.7
Decking, U.K.8
Smith, M.L.9
Sevigny, J.10
Gear, A.11
Weber, A.A.12
Molojavyi, A.13
Ding, Z.14
Weber, C.15
Ley, K.16
Zimmermann, H.17
Godecke, A.18
Schrader, J.19
-
19
-
-
18044384409
-
Role of CD39 (NTPDase-1) in thromboregulation, cerebro-protection and cardioprotection
-
Marcus AJ, Broekman MJ, Drosopoulos JHF, Olson KE, Islam N, Pinsky D, Levi R. Role of CD39 (NTPDase-1) in thromboregulation, cerebro-protection and cardioprotection. Semin Thromb Hemost. 2005;31: 234-246.
-
(2005)
Semin Thromb Hemost
, vol.31
, pp. 234-246
-
-
Marcus, A.J.1
Broekman, M.J.2
Drosopoulos, J.H.F.3
Olson, K.E.4
Islam, N.5
Pinsky, D.6
Levi, R.7
-
20
-
-
38649139068
-
Raised levels of CD39 in leucocytosis result in marked inhibition of ADP-induced aggregation via rapid hydrolysis
-
Glenn JR, White AE, Johnson AJ, Fox SC, Myers B, Heptinstall S. Raised levels of CD39 in leucocytosis result in marked inhibition of ADP-induced aggregation via rapid hydrolysis. Platelets. 2008;19: 59-69.
-
(2008)
Platelets
, vol.19
, pp. 59-69
-
-
Glenn, J.R.1
White, A.E.2
Johnson, A.J.3
Fox, S.C.4
Myers, B.5
Heptinstall, S.6
-
22
-
-
34247566600
-
12 receptor by adenosine diphosphate potentiates the antiplatelet effects of prostacyclin
-
12 receptor by adenosine diphosphate potentiates the antiplatelet effects of prostacyclin. J Thromb Haemost. 2007;5:577-582.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 577-582
-
-
Cattaneo, M.1
Lecchi, A.2
-
23
-
-
0030606020
-
Nucleoside and nucleobase transport systems of mammalian cells
-
Griffith DA, Jarvis SM. Nucleoside and nucleobase transport systems of mammalian cells. Biochim Biophys Acta. 1996;1286:153-181.
-
(1996)
Biochim Biophys Acta
, vol.1286
, pp. 153-181
-
-
Griffith, D.A.1
Jarvis, S.M.2
-
24
-
-
34247334945
-
Physiological roles of vascular nucleoside transporters
-
Loffler M, Morote-Garcia JC, Eltzschig SA, Coe IR, Eltzschig HK. Physiological roles of vascular nucleoside transporters. Arterioscler Thromb Vasc Biol. 2007;27:1004-1013.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 1004-1013
-
-
Loffler, M.1
Morote-Garcia, J.C.2
Eltzschig, S.A.3
Coe, I.R.4
Eltzschig, H.K.5
-
25
-
-
0020564405
-
Dipyridamole inhibition of adenosine metabolism in human blood
-
Klabunde RE. Dipyridamole inhibition of adenosine metabolism in human blood. Eur J Pharmacol. 1983;93:21-26.
-
(1983)
Eur J Pharmacol
, vol.93
, pp. 21-26
-
-
Klabunde, R.E.1
-
26
-
-
0022374265
-
Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine
-
Dawicki DD, Agarwal KC, Parks RE. Role of adenosine uptake and metabolism by blood cells in the antiplatelet actions of dipyridamole, dilazep and nitrobenzylthioinosine. Biochem Pharmacol. 1985;34: 3965-3972.
-
(1985)
Biochem Pharmacol
, vol.34
, pp. 3965-3972
-
-
Dawicki, D.D.1
Agarwal, K.C.2
Parks, R.E.3
-
27
-
-
26444498539
-
Role of adenosine and nitric oxide on the mechanisms of action of dipyridamole
-
Gamboa A, Abraham R, Diedrich A, Shibao C, Paranjape SY, Farley G, Biaggioni I. Role of adenosine and nitric oxide on the mechanisms of action of dipyridamole. Stroke. 2005;36:2170-2175.
-
(2005)
Stroke
, vol.36
, pp. 2170-2175
-
-
Gamboa, A.1
Abraham, R.2
Diedrich, A.3
Shibao, C.4
Paranjape, S.Y.5
Farley, G.6
Biaggioni, I.7
-
28
-
-
43849097254
-
Dipyridamole, cerebrovascular disease and the vasculature
-
Chakrabarti S, Freedman JE. Dipyridamole, cerebrovascular disease and the vasculature. Vasc Pharmacol. 2008;48:143-149.
-
(2008)
Vasc Pharmacol
, vol.48
, pp. 143-149
-
-
Chakrabarti, S.1
Freedman, J.E.2
-
29
-
-
71849097646
-
AZD6140 inhibits adenosine uptake into erythrocytes and enhances coronary blood flow after local ischemia or intracoronary adenosine infusion
-
Abstract 245
-
Bjorkman JA, Kirk I, van Giezen JJ. AZD6140 inhibits adenosine uptake into erythrocytes and enhances coronary blood flow after local ischemia or intracoronary adenosine infusion. Circulation. 2007;116(suppl):II-28 [Abstract 245].
-
(2007)
Circulation
, vol.116
, Issue.SUPPL.
-
-
Bjorkman, J.A.1
Kirk, I.2
Van Giezen, J.J.3
-
30
-
-
0028303913
-
CAMP-and cGMP-protein kinase phosphorylation sites of the focal adhesion vasodilator- stimulated phosphoprotein (VASP) in vitro and in intact human platelets
-
Butt E, Abel K, Krieger M, Palm D, Hoppe V, Hoppe J, Walter U. cAMP-and cGMP-protein kinase phosphorylation sites of the focal adhesion vasodilator- stimulated phosphoprotein (VASP) in vitro and in intact human platelets. J Biol Chem. 1994;269:14509-14517.
-
(1994)
J Biol Chem
, vol.269
, pp. 14509-14517
-
-
Butt, E.1
Abel, K.2
Krieger, M.3
Palm, D.4
Hoppe, V.5
Hoppe, J.6
Walter, U.7
-
32
-
-
0031822884
-
Evidence that adenosine diphosphate can activate adenylate cyclase via conversion to adenosine in platelet-rich plasma containing magnesium
-
Glenn JR, Heptinstall S. Evidence that adenosine diphosphate can activate adenylate cyclase via conversion to adenosine in platelet-rich plasma containing magnesium. Thromb Haemostasis. 1998;80:321-325.
-
(1998)
Thromb Haemostasis
, vol.80
, pp. 321-325
-
-
Glenn, J.R.1
Heptinstall, S.2
-
33
-
-
0042386007
-
Coordinated adenine nucleotide phosphohy-drolysis and nucleoside signaling in posthypoxic endothelium: Role of ectonucleotidases and adenosine A(2B) receptors
-
Eltzschig HK, Ibla JC, Furuta GT, Leonard MO, Jacobson KA, Enjyoji K, Robson SC, Colgan SP. Coordinated adenine nucleotide phosphohy-drolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A(2B) receptors. J Exp Med. 2003;198: 783-796.
-
(2003)
J Exp Med
, vol.198
, pp. 783-796
-
-
Eltzschig, H.K.1
Ibla, J.C.2
Furuta, G.T.3
Leonard, M.O.4
Jacobson, K.A.5
Enjyoji, K.6
Robson, S.C.7
Colgan, S.P.8
-
34
-
-
0037968292
-
Hypoxia enhances ecto-5'-nucleotidase activity and cell surface expression in endothelial cells: Role of membrane lipids
-
Ledoux L, Runembert I, Koumanov K, Michel JB, Trugnan G, Fried-lander G. Hypoxia enhances ecto-5'-nucleotidase activity and cell surface expression in endothelial cells: role of membrane lipids. Circ Res. 2003; 92:848-855.
-
(2003)
Circ Res
, vol.92
, pp. 848-855
-
-
Ledoux, L.1
Runembert, I.2
Koumanov, K.3
Michel, J.B.4
Trugnan, G.5
Fried-Lander, G.6
-
35
-
-
28544446113
-
HIF-1-dependent repression of endothelial equilibrative nucleoside transporter (ENT) in hypoxia
-
Eltzschig HK, Abdulla P, Hoffman E, Hamilton KE, Daniels D, Schonfeld C, Loffler M, Reyes G, Duszenko M, Karhausen J, Robinson A, Westerman KA, Coe IR, Colgan SP. HIF-1-dependent repression of endothelial equilibrative nucleoside transporter (ENT) in hypoxia. J Exp Med. 2005;202:1493-1505.
-
(2005)
J Exp Med
, vol.202
, pp. 1493-1505
-
-
Eltzschig, H.K.1
Abdulla, P.2
Hoffman, E.3
Hamilton, K.E.4
Daniels, D.5
Schonfeld, C.6
Loffler, M.7
Reyes, G.8
Duszenko, M.9
Karhausen, J.10
Robinson, A.11
Westerman, K.A.12
Coe, I.R.13
Colgan, S.P.14
-
36
-
-
0034781382
-
Effects of combining three different antiplatelet agents on platelets and leukocytes in whole blood in vitro
-
Zhao L, Bath P, Heptinstall S. Effects of combining three different antiplatelet agents on platelets and leukocytes in whole blood in vitro. Br J Pharmacol. 2001;134:253-258.
-
(2001)
Br J Pharmacol
, vol.134
, pp. 253-258
-
-
Zhao, L.1
Bath, P.2
Heptinstall, S.3
-
37
-
-
3042715252
-
Triple antiplatelet therapy for secondary prevention of recurrent ischemic stroke
-
Willmot M, Zhao L, Heptinstall S, Bath P. Triple antiplatelet therapy for secondary prevention of recurrent ischemic stroke. J Stroke Cerebrovasc Dis. 2004;13:138-140.
-
(2004)
J Stroke Cerebrovasc Dis
, vol.13
, pp. 138-140
-
-
Willmot, M.1
Zhao, L.2
Heptinstall, S.3
Bath, P.4
-
38
-
-
15344342087
-
Effects of aspirin, clopidogrel and dipyridamole administered singly and in combination on platelet and leucocyte function in normal volunteers and patients with prior ischaemic stroke
-
Zhao L, Fletcher S, Weaver C, Leonardi-Bee J, May J, Fox S, Willmot M, Heptinstall S, Bath O. Effects of aspirin, clopidogrel and dipyridamole administered singly and in combination on platelet and leucocyte function in normal volunteers and patients with prior ischaemic stroke. Thromb Haemostasis. 2005;93:527-534.
-
(2005)
Thromb Haemostasis
, vol.93
, pp. 527-534
-
-
Zhao, L.1
Fletcher, S.2
Weaver, C.3
Leonardi-Bee, J.4
May, J.5
Fox, S.6
Willmot, M.7
Heptinstall, S.8
Bath, O.9
-
39
-
-
51349157097
-
A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: Safety, tolerability and feasibility
-
Sprigg N, Gray LJ, England T, Willmot MR, Zhao L, Sare GM, Bath PM. A randomised controlled trial of triple antiplatelet therapy (aspirin, clopidogrel and dipyridamole) in the secondary prevention of stroke: safety, tolerability and feasibility. PLoS One. 2008;3:e2852.
-
(2008)
PLoS One
, vol.3
-
-
Sprigg, N.1
Gray, L.J.2
England, T.3
Willmot, M.R.4
Zhao, L.5
Sare, G.M.6
Bath, P.M.7
-
40
-
-
77950259992
-
Effect of combined aspirin and extended-release dipyridamole versus clopidogrel on functional outcome and recurrence in acute, mild ischemic stroke: PRoFESS subgroup analysis
-
PRoFESS Study Group
-
Bath PM, Cotton D, Martin RH, Palesch Y, Yusuf S, Sacco R, Diener HC, Estol C, Roberts R; PRoFESS Study Group. Effect of combined aspirin and extended-release dipyridamole versus clopidogrel on functional outcome and recurrence in acute, mild ischemic stroke: PRoFESS subgroup analysis. Stroke. 2010;41:732-738.
-
(2010)
Stroke
, vol.41
, pp. 732-738
-
-
Bath, P.M.1
Cotton, D.2
Martin, R.H.3
Palesch, Y.4
Yusuf, S.5
Sacco, R.6
Diener, H.C.7
Estol, C.8
Roberts, R.9
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