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Volumn 59, Issue 13, 1999, Pages 3059-3063

Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYCYCLOPHOSPHAMIDE; ACROLEIN; CYCLOPHOSPHAMIDE; CYCLOPHOSPHAMIDE DERIVATIVE; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; PHOSPHORAMIDE MUSTARD; DNA ALKYLTRANSFERASE; DRUG DERIVATIVE; MUTAGENIC AGENT; PERFOSFAMIDE; RECOMBINANT PROTEIN; TRANSFERASE;

EID: 0033153762     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (50)

References (27)
  • 3
    • 0024245628 scopus 로고
    • Acute non-lymphocytic leukemia following short-term, intermittent, intravenous cyclophosphamide treatment of lupus nephritis
    • Gibbons, R. B., and Westerman, E. Acute non-lymphocytic leukemia following short-term, intermittent, intravenous cyclophosphamide treatment of lupus nephritis. Arthritis Rheum., 31: 1552-1554, 1988.
    • (1988) Arthritis Rheum. , vol.31 , pp. 1552-1554
    • Gibbons, R.B.1    Westerman, E.2
  • 4
    • 0026599235 scopus 로고
    • Bladder cancer after cyclophosphamide therapy for lupus nephritis
    • Ortiz, A., Gonzalez-Parra, E., Aloarez-Costa, G., and Egido, J. Bladder cancer after cyclophosphamide therapy for lupus nephritis. Nephron, 60: 378-379, 1992.
    • (1992) Nephron , vol.60 , pp. 378-379
    • Ortiz, A.1    Gonzalez-Parra, E.2    Aloarez-Costa, G.3    Egido, J.4
  • 5
    • 0029154091 scopus 로고
    • Cyclophosphamide. Review of its mutagenicity for an assessment of potential germ cell risks
    • Anderson, D., Bishop, J. B., Garner, R. C., Ostrosky-Wegman, P., and Selby, P. B. Cyclophosphamide. Review of its mutagenicity for an assessment of potential germ cell risks. Mutat. Res., 330: 115-181, 1995.
    • (1995) Mutat. Res. , vol.330 , pp. 115-181
    • Anderson, D.1    Bishop, J.B.2    Garner, R.C.3    Ostrosky-Wegman, P.4    Selby, P.B.5
  • 6
    • 0021319465 scopus 로고
    • 2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde
    • 2-propanodeoxyguanosine adducts in DNA upon reaction with acrolein or crotonaldehyde. Cancer Res., 44: 990-995, 1984.
    • (1984) Cancer Res. , vol.44 , pp. 990-995
    • Chung, F.1    Young, R.2    Hecht, S.S.3
  • 7
    • 0022358539 scopus 로고
    • Binding of metabolites of cyclophosphamide to DNA in a rat liver microsomal system and in vivo in mice
    • Hemminki, K. Binding of metabolites of cyclophosphamide to DNA in a rat liver microsomal system and in vivo in mice. Cancer Res., 45: 4237-4243, 1985.
    • (1985) Cancer Res. , vol.45 , pp. 4237-4243
    • Hemminki, K.1
  • 9
    • 0028177572 scopus 로고
    • 6-Methylguanine-DNA methyltransferase in ovarian malignancy and its correlation with postoperative response to chemotherapy
    • 6-Methylguanine-DNA methyltransferase in ovarian malignancy and its correlation with postoperative response to chemotherapy. Gynecol. Oncol., 52: 172-174, 1994.
    • (1994) Gynecol. Oncol. , vol.52 , pp. 172-174
    • Chen, S.S.1    Citron, M.2    Spiegel, G.3    Yarosh, D.4
  • 10
    • 0031128016 scopus 로고    scopus 로고
    • Expression of genes of potential importance in the response to chemotherapy and DNA repair in patients with ovarian cancer
    • Codegoni, A. M., Broggini, M., Pitelli, M. R., Pantapotto, M., Torri, V., Mangioni, C., and Incalci, M. D. Expression of genes of potential importance in the response to chemotherapy and DNA repair in patients with ovarian cancer, Gynecol. Oncol., 65: 130-137, 1997.
    • (1997) Gynecol. Oncol. , vol.65 , pp. 130-137
    • Codegoni, A.M.1    Broggini, M.2    Pitelli, M.R.3    Pantapotto, M.4    Torri, V.5    Mangioni, C.6    Incalci, M.D.7
  • 12
    • 0021238317 scopus 로고
    • NMR spectroscopic studies of intermediary metabolites of cyclophosphamide. A comprehensive kinetic analysis of the interconversion of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and the concomitant partitioning of aldophosphamide between irreversible fragmentation and reversible conjugation path ways
    • Zon, G., Ludeman, S. M., Brandt, J. A., Boyd, V. L., Ozkan, G., Egan, W., and Shao, K. L. NMR spectroscopic studies of intermediary metabolites of cyclophosphamide. A comprehensive kinetic analysis of the interconversion of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and the concomitant partitioning of aldophosphamide between irreversible fragmentation and reversible conjugation path ways. J. Med. Chem., 27: 466-485, 1984.
    • (1984) J. Med. Chem. , vol.27 , pp. 466-485
    • Zon, G.1    Ludeman, S.M.2    Brandt, J.A.3    Boyd, V.L.4    Ozkan, G.5    Egan, W.6    Shao, K.L.7
  • 14
    • 0025196019 scopus 로고
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents
    • 6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents. Proc. Natl. Acad. Sci. USA, 87: 5368-5372, 1990.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5368-5372
    • Dolan, M.E.1    Moschel, R.C.2    Pegg, A.E.3
  • 15
    • 0025924488 scopus 로고
    • 6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents
    • 6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents. Cancer Res., 51: 3367-3372, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 3367-3372
    • Dolan, M.E.1    Mitchell, R.B.2    Mummert, C.3    Moschel, R.C.4    Pegg, A.E.5
  • 16
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72: 248-254, 1976.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 17
    • 0021646476 scopus 로고
    • 6-methylguanine DNA-methyltransferase activity and resistance of human cells to the cytotoxic and mutagenic effect of N-methyl-N′-nitro-N-nitrosoguanidine
    • 6-methylguanine DNA-methyltransferase activity and resistance of human cells to the cytotoxic and mutagenic effect of N-methyl-N′-nitro-N-nitrosoguanidine. Carcinogenesis (Lond.), 5: 1641-1647, 1984.
    • (1984) Carcinogenesis (Lond.) , vol.5 , pp. 1641-1647
    • Domoradzki, J.1    Pegg, A.E.2    Dolan, M.E.3    Maher, V.M.4    McCormick, J.J.5
  • 18
    • 0031594831 scopus 로고    scopus 로고
    • 6-Methylguanine-DNA methyltransferase activity and sensitivity to cyclophosphamide and cisplatin in human lung tumor xenografts
    • 6-Methylguanine-DNA methyltransferase activity and sensitivity to cyclophosphamide and cisplatin in human lung tumor xenografts. Int. J. Cancer, 77: 919-922, 1998.
    • (1998) Int. J. Cancer , vol.77 , pp. 919-922
    • Mattern, J.1    Eichhorn, U.2    Kaina, B.3    Volm, M.4
  • 19
    • 0029664534 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs
    • 6-methylguanine-DNA methyltransferase (MGMT) on the cytotoxic and recombinogenic activity of different antineoplastic drugs. Int. J. Cancer, 65: 506-512, 1996.
    • (1996) Int. J. Cancer , vol.65 , pp. 506-512
    • Preuss, I.1    Thust, R.2    Kaina, B.3
  • 21
    • 0022444380 scopus 로고
    • Glutathione depletion as a determinant of sensitivity of human leukemia cells to cyclophosphamide
    • Crook, T. R., Souhami, R. L., Whyman, G. D., and Mclean, A. E. M. Glutathione depletion as a determinant of sensitivity of human leukemia cells to cyclophosphamide. Cancer Res., 46: 5035-5038, 1986.
    • (1986) Cancer Res. , vol.46 , pp. 5035-5038
    • Crook, T.R.1    Souhami, R.L.2    Whyman, G.D.3    Mclean, A.E.M.4
  • 22
    • 0026766227 scopus 로고
    • Acrolein initiates rat urinary bladder carcinogenesis
    • Cohen, S. M., Garland, E. M., John, M., Okamura, T., and Smith, R. Acrolein initiates rat urinary bladder carcinogenesis. Cancer Res., 52: 3577-3581, 1992.
    • (1992) Cancer Res. , vol.52 , pp. 3577-3581
    • Cohen, S.M.1    Garland, E.M.2    John, M.3    Okamura, T.4    Smith, R.5
  • 24
    • 0023818614 scopus 로고
    • 6-alkylguanine DNA alkyltransferase activity in the peripheral blood lymphocytes of patients with therapy-related acute nonlymphocytic leukemia
    • 6-alkylguanine DNA alkyltransferase activity in the peripheral blood lymphocytes of patients with therapy-related acute nonlymphocytic leukemia. Cancer Res., 48: 3084-3089, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 3084-3089
    • Sagher, D.1    Karrison, T.2    Schwartz, J.L.3    Larson, R.4    Meier, P.5    Strauss, B.6
  • 27
    • 0024210285 scopus 로고
    • The reaction of sulfhydryl groups with carbonyl compounds
    • Wlodek, L. The reaction of sulfhydryl groups with carbonyl compounds. Acta Biochim. Pol., 35: 307-317, 1988.
    • (1988) Acta Biochim. Pol. , vol.35 , pp. 307-317
    • Wlodek, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.