-
1
-
-
38049098496
-
Stability and structure studies on alisol A 24-acetate
-
B. Makabel, Y. Y. Zhao, B. Wang, Y. J. Bai, Q. Y. Zhang, L. Wu, Y. Lv. Stability and structure studies on alisol A 24-acetate. Chem. Pharm. Bull. 2008, 56, 41.
-
(2008)
Chem. Pharm. Bull.
, vol.56
, pp. 41
-
-
Makabel, B.1
Zhao, Y.Y.2
Wang, B.3
Bai, Y.J.4
Zhang, Q.Y.5
Wu, L.6
Lv, Y.7
-
2
-
-
33846397852
-
Reversal of multidrug resistance in cancer cells by rhizoma alismatis extract
-
W. F. Fong, C. Wang, G. Y. Zhu, C. H. Leung, M. S. Yang. Reversal of multidrug resistance in cancer cells by rhizoma alismatis extract. Phytomedicine 2007, 14, 160.
-
(2007)
Phytomedicine
, vol.14
, pp. 160
-
-
Fong, W.F.1
Wang, C.2
Zhu, G.Y.3
Leung, C.H.4
Yang, M.S.5
-
3
-
-
85159252834
-
The pharmaco-research of rhizoma alismatis on lowing blood-fat
-
Institute of Materia Medica, Zhejiang Province People's Health Administration
-
Institute of Materia Medica, Zhejiang Province People's Health Administration. The pharmaco-research of rhizoma alismatis on lowing blood-fat. Chin. Tradit. Herbal. Drugs 1976, 7, 26.
-
(1976)
Chin. Tradit. Herbal. Drugs
, vol.7
, pp. 26
-
-
-
4
-
-
77954097336
-
-
China Press of Traditional Chinese Medicine, Beijing
-
T. Ding, Adverse Reactions, Prevention, and Cures of Chinese Herbal Medicine, China Press of Traditional Chinese Medicine, Beijing, 1992.
-
(1992)
Adverse Reactions, Prevention, and Cures of Chinese Herbal Medicine
-
-
Ding, T.1
-
5
-
-
67049173139
-
Discovery of metabolomics biomarkers for early detectionof nephrotoxicity
-
K. J. Boudonck, M. W. Mitchell, L. Német, L. Keresztes, A. Nyska, D. Shinar, M. Rosenstock. Discovery of metabolomics biomarkers for early detectionof nephrotoxicity. Toxicol. Pathol. 2009, 37, 280.
-
(2009)
Toxicol. Pathol.
, vol.37
, pp. 280
-
-
Boudonck, K.J.1
Mitchell, M.W.2
Német, L.3
Keresztes, L.4
Nyska, A.5
Shinar, D.6
Rosenstock, M.7
-
6
-
-
0032694577
-
'Metabonomics' understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
-
J. K. Nicholson, J. C. Lindon, E. Holmes. 'Metabonomics' understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data. Xenobiotica 1999, 29, 1181.
-
(1999)
Xenobiotica
, vol.29
, pp. 1181
-
-
Nicholson, J.K.1
Lindon, J.C.2
Holmes, E.3
-
7
-
-
77949417518
-
Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity
-
R. D. Beger, J. Sun, L. K. Schnackenberg. Metabolomics approaches for discovering biomarkers of drug-induced hepatotoxicity and nephrotoxicity. Toxicol. Appl. Pharmacol. 2010, 243, 154.
-
(2010)
Toxicol. Appl. Pharmacol.
, vol.243
, pp. 154
-
-
Beger, R.D.1
Sun, J.2
Schnackenberg, L.K.3
-
8
-
-
85151350509
-
-
Amsterdam
-
J. C. Lindon, J. K. Nicholson, E. Holmes, The Handbook of Metabonomics and Metabolomics, Elsevier, Amsterdam, 2007.
-
(2007)
The Handbook of Metabonomics and Metabolomics, Elsevier
-
-
Lindon, J.C.1
Nicholson, J.K.2
Holmes, E.3
-
9
-
-
72049115542
-
Effect of mitiglinide on Streptozotocin-induced experimental type 2 diabetic rats: A urinary metabonomics study based on ultra-performance liquid chromatography-tandem mass spectrometry
-
S. Cai, T. G. Huo, J. H. Xu, X. M. Lu, S. N. Zheng, F. M. Li. Effect of mitiglinide on Streptozotocin-induced experimental type 2 diabetic rats: a urinary metabonomics study based on ultra-performance liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 2009, 877, 3619.
-
(2009)
J. Chromatogr. B
, vol.877
, pp. 3619
-
-
Cai, S.1
Huo, T.G.2
Xu, J.H.3
Lu, X.M.4
Zheng, S.N.5
Li, F.M.6
-
10
-
-
39149086688
-
Aristolochic acid induced changes in the metabolic profile of rat urine
-
W. Chan, Z. W. Cai. Aristolochic acid induced changes in the metabolic profile of rat urine. J. Pharm. Biomed. Anal. 2008, 46, 757.
-
(2008)
J. Pharm. Biomed. Anal.
, vol.46
, pp. 757
-
-
Chan, W.1
Cai, Z.W.2
-
11
-
-
85159251166
-
-
KEGG. Available: http://www.genome.jp/kegg/.
-
-
-
-
12
-
-
85159246699
-
-
MassBank. Available: http://www.massbank.jp/
-
MassBank
-
-
-
13
-
-
85159251524
-
-
HMDB. Available: http://www.hmdb.ca/search/spectra? type=ms-ms search.
-
-
-
-
14
-
-
85159256562
-
-
METLIN. Available: http://metlin. scripps.edu/.
-
-
-
-
15
-
-
77954315742
-
Plasma metabolic profiling of Alzheimer's disease by liquid chromatography/mass spectrometry
-
N. J. Li, W. T. Liu, W. Li, S. Q. Li, X. H. Chen, K. S. Bi, P. He. Plasma metabolic profiling of Alzheimer's disease by liquid chromatography/mass spectrometry. Clin. Biochem. 2010, 43, 992.
-
(2010)
Clin. Biochem.
, vol.43
, pp. 992
-
-
Li, N.J.1
Liu, W.T.2
Li, W.3
Li, S.Q.4
Chen, X.H.5
Bi, K.S.6
He, P.7
-
16
-
-
77956344105
-
A serum and kidney metabolic changes of rat nephrotoxicity induced by Morning Glory Seed
-
C. Ma, K. S. Bi, D. Su, W. Ji, M. Zhang, X. X. Fan, C. Wang, X. H. Chen. A serum and kidney metabolic changes of rat nephrotoxicity induced by Morning Glory Seed. Food Chem. Toxicol. 2010, 48, 2988.
-
(2010)
Food Chem. Toxicol.
, vol.48
, pp. 2988
-
-
Ma, C.1
Bi, K.S.2
Su, D.3
Ji, W.4
Zhang, M.5
Fan, X.X.6
Wang, C.7
Chen, X.H.8
-
17
-
-
34548356352
-
Metabolomic and genetic analysis of biomarkers for peroxisome proliferator activated receptor {alpha} expression and activation
-
Y. Y. Zhen, K. W. Krausz, C. Chen, J. R. Idle, F. J. Gonzalez. Metabolomic and genetic analysis of biomarkers for peroxisome proliferator activated receptor {alpha} expression and activation. Mol. Endocrinol. 2007, 21, 2136.
-
(2007)
Mol. Endocrinol.
, vol.21
, pp. 2136
-
-
Zhen, Y.Y.1
Krausz, K.W.2
Chen, C.3
Idle, J.R.4
Gonzalez, F.J.5
-
18
-
-
74449084552
-
Systems toxicology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics
-
J. Wang, T. Reijmers, L. J. Chen, R. V. D. Heijden, M. Wang, S. Q. Peng, T. Hankemeier, G. W. Xu, J. Van der Greef. Systems toxicology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics. Metabolomics 2009, 5, 407.
-
(2009)
Metabolomics
, vol.5
, pp. 407
-
-
Wang, J.1
Reijmers, T.2
Chen, L.J.3
Heijden, R.V.D.4
Wang, M.5
Peng, S.Q.6
Hankemeier, T.7
Xu, G.W.8
Van Der Greef, J.9
-
19
-
-
80052597153
-
The role of the liver in hippuric acid synthesis
-
E. Lackner, A. Levinson, W. Morse. The role of the liver in hippuric acid synthesis. Biochem. J. 1918, 12, 184.
-
(1918)
Biochem. J.
, vol.12
, pp. 184
-
-
Lackner, E.1
Levinson, A.2
Morse, W.3
-
20
-
-
0028063899
-
Serum hippuric acid concentration in renal allograft rejection, ureter obstruction, and tubular necrosis
-
A. Knoflach, U. Binswanger. Serum hippuric acid concentration in renal allograft rejection, ureter obstruction, and tubular necrosis. Transpl. Int. 1994, 7, 17.
-
(1994)
Transpl. Int.
, vol.7
, pp. 17
-
-
Knoflach, A.1
Binswanger, U.2
-
21
-
-
0345714918
-
NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats
-
A. W. Nicholls, R. J. Mortishire-Smith, J. K. Nicholson. NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats. Chem. Res. Toxicol. 2003, 16, 1395.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 1395
-
-
Nicholls, A.W.1
Mortishire-Smith, R.J.2
Nicholson, J.K.3
-
22
-
-
12344311533
-
A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion
-
Y. Wang, H. Tang, J. K. Nicholson, P. J. Hylands, J. Sampson, E. Holmes. A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion. J. Agric. Food Chem. 2005, 53, 191.
-
(2005)
J. Agric. Food Chem.
, vol.53
, pp. 191
-
-
Wang, Y.1
Tang, H.2
Nicholson, J.K.3
Hylands, P.J.4
Sampson, J.5
Holmes, E.6
-
23
-
-
26844548140
-
-
State Administration of Traditional Chinese Medicine, Shanghai scientific & Technical Publishers, Shanghai
-
State Administration of Traditional Chinese Medicine. Chinese Materia Medica, Shanghai scientific & Technical Publishers, Shanghai, 2004.
-
(2004)
Chinese Materia Medica
-
-
-
24
-
-
55949097069
-
Temporal metabonomic modeling of L-arginine-induced exocrine pancreatitis
-
E. Bohus, M. Coen, H. C. Keun, T. M. D. Ebbels, J. C. Lindon, E. Holmes, B. Nosza, J. K. Nicholson. Temporal metabonomic modeling of L-arginine-induced exocrine pancreatitis. J. Proteome. Res. 2008, 7, 4435.
-
(2008)
J. Proteome. Res.
, vol.7
, pp. 4435
-
-
Bohus, E.1
Coen, M.2
Keun, H.C.3
Ebbels, T.M.D.4
Lindon, J.C.5
Holmes, E.6
Nosza, B.7
Nicholson, J.K.8
-
25
-
-
0034530607
-
A metabonomic approach to the investigation of drug-induced phospholipidosis: An NMR spectroscopy and pattern recognition study
-
A. W. Nicholls, J. K. Nicholson, J. N. Haselden, C. J. Waterfield. A metabonomic approach to the investigation of drug-induced phospholipidosis: an NMR spectroscopy and pattern recognition study. Biomarkers 2000, 5, 410.
-
(2000)
Biomarkers
, vol.5
, pp. 410
-
-
Nicholls, A.W.1
Nicholson, J.K.2
Haselden, J.N.3
Waterfield, C.J.4
-
26
-
-
0033935979
-
Creatine and creatine metabolism
-
M. Wyss. Creatine and creatine metabolism. Physiol. Rev. 2000, 80, 1107.
-
(2000)
Physiol. Rev.
, vol.80
, pp. 1107
-
-
Wyss, M.1
-
27
-
-
85159254646
-
-
The Human Metabolome Database. http://www.hmdb.ca/metabolites/HMDB00562.
-
-
-
-
28
-
-
0034057069
-
Peroxisome proliferator-activated receptors in the cardiovascular system
-
D. Bishop-Bailey. Peroxisome proliferator-activated receptors in the cardiovascular system. Br. J. Pharmacol. 2000, 129, 823.
-
(2000)
Br. J. Pharmacol.
, vol.129
, pp. 823
-
-
Bishop-Bailey, D.1
-
29
-
-
0036865166
-
Peroxisome proliferator-activated receptors and the regulation of mammalian lipid metabolism
-
S. A. Smith. Peroxisome proliferator-activated receptors and the regulation of mammalian lipid metabolism. Biochem. Soc. Trans. 2002, 30, 1086.
-
(2002)
Biochem. Soc. Trans.
, vol.30
, pp. 1086
-
-
Smith, S.A.1
-
30
-
-
0034951366
-
Peroxisome proliferator-activated receptors (PPARs): Novel therapeutic targets in renal disease
-
Y. Guan, M. D. Breyer. Peroxisome proliferator-activated receptors (PPARs): novel therapeutic targets in renal disease. Kidney Int. 2001, 60, 14.
-
(2001)
Kidney Int.
, vol.60
, pp. 14
-
-
Guan, Y.1
Breyer, M.D.2
-
31
-
-
0035078484
-
Etiopathogenesis of nonalcoholic steatohepatitis
-
S. Chitturi, G. C. Farrell. Etiopathogenesis of nonalcoholic steatohepatitis. Semin. Liver Dis. 2001, 21, 27.
-
(2001)
Semin. Liver Dis.
, vol.21
, pp. 27
-
-
Chitturi, S.1
Farrell, G.C.2
-
33
-
-
0034562783
-
Reactive oxygen species and acute renal failure
-
MB ChB, MD
-
K. A. MB ChB Nath, S. M. MD Norby. Reactive oxygen species and acute renal failure. Am. J. Med. 2000, 109, 665.
-
(2000)
Am. J. Med.
, vol.109
, pp. 665
-
-
Nath, K.A.1
Norby, S.M.2
-
34
-
-
0014117577
-
Effect of administration of the carcinogen dimethylnitrosamine on urinary 7-methylguanine
-
V. M. Craddock, P. N. Magee. Effect of administration of the carcinogen dimethylnitrosamine on urinary 7-methylguanine. Biochem. J. 1967, 104, 435.
-
(1967)
Biochem. J.
, vol.104
, pp. 435
-
-
Craddock, V.M.1
Magee, P.N.2
-
35
-
-
67449097580
-
Effect of age, smoking and other lifestyle factors on urinary 7-methylguanine and 8-hydroxydeoxyguanosine
-
K. Tamae, K. Kawai, S. Yamasaki, K. Kawanami, M. Ikeda, K. Takahashi, T. Miyamoto, N. Kato, H. Kasai. Effect of age, smoking and other lifestyle factors on urinary 7-methylguanine and 8-hydroxydeoxyguanosine. Cancer Sci. 2009, 100, 715.
-
(2009)
Cancer Sci.
, vol.100
, pp. 715
-
-
Tamae, K.1
Kawai, K.2
Yamasaki, S.3
Kawanami, K.4
Ikeda, M.5
Takahashi, K.6
Miyamoto, T.7
Kato, N.8
Kasai, H.9
-
36
-
-
0021959881
-
Urinary hypoxanthine and pseudouridine as indicators of tumor development in mesothelioma-transplanted nude mice
-
L. Buhl, C. Dragsholt, P. Svendsen, E. Hage, M. R. Buhl. Urinary hypoxanthine and pseudouridine as indicators of tumor development in mesothelioma-transplanted nude mice. Cancer Res. 1985, 45, 1159.
-
(1985)
Cancer Res.
, vol.45
, pp. 1159
-
-
Buhl, L.1
Dragsholt, C.2
Svendsen, P.3
Hage, E.4
Buhl, M.R.5
-
37
-
-
3042517107
-
1H NMR and HPLC-TOF/MS: Time dependant changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity
-
1H NMR and HPLC-TOF/MS: time dependant changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity. Analyst 2004, 129, 535.
-
(2004)
Analyst
, vol.129
, pp. 535
-
-
Lenz, E.M.1
Bright, J.2
Knight, R.3
Wilson, D.4
Major, H.5
-
38
-
-
4444311570
-
Mitochondrially-mediated toxicity of bile acids
-
C. M. Palmeira, A. P. Rolo. Mitochondrially-mediated toxicity of bile acids. Toxicology 2004, 203, 1.
-
(2004)
Toxicology
, vol.203
, pp. 1
-
-
Palmeira, C.M.1
Rolo, A.P.2
-
39
-
-
0000904366
-
-
Eds: N. Tavolin, P. D. Berk. Raven Press, New York
-
J. D. Ostrow, in Hepatic Transport and Bile Secretion: Physiology and Pathophysiology, (Eds: N. Tavolin, P. D. Berk). Raven Press, New York, 1993, pp. 673-712.
-
(1993)
Hepatic Transport and Bile Secretion: Physiology and Pathophysiology
, pp. 673-712
-
-
Ostrow, J.D.1
-
41
-
-
0010670423
-
Renal excretion of bile acids: Taurocholic, glycocholic and cholic acids
-
I. M. Weiner, J. E. Glasser, L. Lack. Renal excretion of bile acids: taurocholic, glycocholic and cholic acids. Am. J. Physiol. 1964, 2076, 964.
-
(1964)
Am. J. Physiol.
, vol.2076
, pp. 964
-
-
Weiner, I.M.1
Glasser, J.E.2
Lack, L.3
-
42
-
-
0017713544
-
The role of tubular reabsorption in the renal excretion of bile acids
-
S. Barnes, J. L. Gollan, B. H. Billing. The role of tubular reabsorption in the renal excretion of bile acids. Biochem. J. 1977, 166, 65.
-
(1977)
Biochem. J.
, vol.166
, pp. 65
-
-
Barnes, S.1
Gollan, J.L.2
Billing, B.H.3
-
43
-
-
5444223495
-
Are bile acids involved in the renal dysfunction of obstructive jaundice? An experimental study in bile duct ligated rats
-
B. Kaler, T. Karram, W. A. Morgan, P. H. Bach, I. M. Yousef, A. Bomzon. Are bile acids involved in the renal dysfunction of obstructive jaundice? An experimental study in bile duct ligated rats. Ren. Fail. 2004, 26, 507.
-
(2004)
Ren. Fail.
, vol.26
, pp. 507
-
-
Kaler, B.1
Karram, T.2
Morgan, W.A.3
Bach, P.H.4
Yousef, I.M.5
Bomzon, A.6
-
44
-
-
0016711425
-
Renal failure in obstructive jaundice-pathogenic factors
-
E. N. Wardle. Renal failure in obstructive jaundice-pathogenic factors. Postgrad. Med. J. 1975, 51, 512.
-
(1975)
Postgrad. Med. J.
, vol.51
, pp. 512
-
-
Wardle, E.N.1
-
45
-
-
0031948346
-
The relationship between sodium chloride concentration and bile acid cytotoxicity in cultured kidney cells
-
W. A. Morgan, Y. Dingg, P. H. Bach. The relationship between sodium chloride concentration and bile acid cytotoxicity in cultured kidney cells. Ren. Fail. 1998, 20, 441.
-
(1998)
Ren. Fail.
, vol.20
, pp. 441
-
-
Morgan, W.A.1
Dingg, Y.2
Bach, P.H.3
-
46
-
-
33745452678
-
Organization and functions of sphingolipid biosynthesis in yeast
-
H. Riezman. Organization and functions of sphingolipid biosynthesis in yeast. Biochem. Soc. Trans. 2006, 34, 367.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 367
-
-
Riezman, H.1
-
47
-
-
0024508863
-
Sphingolipid biosynthesis by rat liver cells: Effects of serine, fatty acids and lipoproteins
-
T. O. Messmer, E. Wang, V. L. Stevens, A. H. Merrill, Jr. Sphingolipid biosynthesis by rat liver cells: effects of serine, fatty acids and lipoproteins. J. Nutr. 1989, 119, 534.
-
(1989)
J. Nutr.
, vol.119
, pp. 534
-
-
Messmer, T.O.1
Wang, E.2
Stevens, V.L.3
Merrill Jr., A.H.4
|