메뉴 건너뛰기




Volumn 179, Issue 2, 2011, Pages 725-732

Inhibition of fas ligand in NOD mice unmasks a protective role for IL-10 against insulitis development

Author keywords

[No Author keywords available]

Indexed keywords

CD5 ANTIGEN; FAS LIGAND; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR;

EID: 80052501666     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.04.016     Document Type: Article
Times cited : (26)

References (47)
  • 1
    • 0033571320 scopus 로고    scopus 로고
    • Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway
    • D. Ashany, A. Savir, N. Bhardwaj, and K.B. Elkon Dendritic cells are resistant to apoptosis through the Fas (CD95/APO-1) pathway J Immunol 163 1999 5303 5311
    • (1999) J Immunol , vol.163 , pp. 5303-5311
    • Ashany, D.1    Savir, A.2    Bhardwaj, N.3    Elkon, K.B.4
  • 2
    • 0344737674 scopus 로고    scopus 로고
    • Fas ligation induces IL-1β-dependent maturation and IL-1β-independent survival of dendritic cells: Different roles of ERK and NF-κB signaling pathways
    • DOI 10.1182/blood-2002-11-3420
    • Z. Guo, M. Zhang, H. An, W. Chen, S. Liu, J. Guo, Y. Yu, and X. Cao Fas ligation induces IL-1beta-dependent maturation and IL-1beta-independent survival of dendritic cells: different roles of ERK and NF-kappaB signaling pathways Blood 102 2003 4441 4447 (Pubitemid 37494108)
    • (2003) Blood , vol.102 , Issue.13 , pp. 4441-4447
    • Guo, Z.1    Zhang, M.2    An, H.3    Chen, W.4    Liu, S.5    Guo, J.6    Yu, Y.7    Cao, X.8
  • 3
    • 24744434621 scopus 로고    scopus 로고
    • Fas signal links innate and adaptive immunity by promoting dendritic-cell secretion of CC and CXC chemokines
    • DOI 10.1182/blood-2004-12-4831
    • Z. Guo, M. Zhang, H. Tang, and X. Cao Fas signal links innate and adaptive immunity by promoting dendritic-cell secretion of CC and CXC chemokines Blood 106 2005 2033 2041 (Pubitemid 41291717)
    • (2005) Blood , vol.106 , Issue.6 , pp. 2033-2041
    • Quo, Z.1    Zhang, M.2    Tang, H.3    Cao, X.4
  • 5
    • 0034606290 scopus 로고    scopus 로고
    • Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL)-1beta, and the production of interferon gamma in the absence of IL-12 during DC-T cell cognate interaction: A new role for Fas ligand in inflammatory responses
    • M. Rescigno, V. Piguet, B. Valzasina, S. Lens, R. Zubler, L. French, V. Kindler, J. Tschopp, and P. Ricciardi-Castagnoli Fas engagement induces the maturation of dendritic cells (DCs), the release of interleukin (IL)-1beta, and the production of interferon gamma in the absence of IL-12 during DC-T cell cognate interaction: a new role for Fas ligand in inflammatory responses J Exp Med 192 2000 1661 1668
    • (2000) J Exp Med , vol.192 , pp. 1661-1668
    • Rescigno, M.1    Piguet, V.2    Valzasina, B.3    Lens, S.4    Zubler, R.5    French, L.6    Kindler, V.7    Tschopp, J.8    Ricciardi-Castagnoli, P.9
  • 7
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
    • DOI 10.1146/annurev.immunol.17.1.221
    • M. Lenardo, F. Chan, F. Hornug, H. McFarland, R. Siegel, J. Wang, and L. Zheng Mature T lymphocytes apoptosis-immune regulation in a dynamic and unpredictable antigenic environment Annu Rev Immunol 17 1999 221 253 (Pubitemid 29241124)
    • (1999) Annual Review of Immunology , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, F.K.-M.2    Hornung, F.3    McFarland, H.4    Siegel, R.5    Wang, J.6    Zheng, L.7
  • 8
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • DOI 10.1016/0092-8674(94)90375-1
    • T. Takahashi, M. Tanaka, C.I. Brannan, N.A. Jenkins, N.G. Copeland, T. Suda, and S. Nagata Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand Cell 76 1994 969 976 (Pubitemid 24106378)
    • (1994) Cell , vol.76 , Issue.6 , pp. 969-976
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 9
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • R. Watanabe-Fukunaga, C. Brannan, N. Copeland, N. Jenkins, and S. Nagata Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis Nature 356 1992 314 317
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.2    Copeland, N.3    Jenkins, N.4    Nagata, S.5
  • 11
    • 77953962836 scopus 로고    scopus 로고
    • Analysis of gene profile, steady state proliferation and apoptosis of double-negative T cells in the periphery and gut epithelium provides new insights into the biological functions of the Fas pathway
    • A.R. Hamad Analysis of gene profile, steady state proliferation and apoptosis of double-negative T cells in the periphery and gut epithelium provides new insights into the biological functions of the Fas pathway Immunol Res 47 2010 134 142
    • (2010) Immunol Res , vol.47 , pp. 134-142
    • Hamad, A.R.1
  • 12
    • 0028980902 scopus 로고
    • Fas and Fas ligand: Lpr and gld mutations
    • S. Nagata, and T. Suda Fas and Fas ligand: lpr and gld mutations Immunol Today 16 1995 39 43
    • (1995) Immunol Today , vol.16 , pp. 39-43
    • Nagata, S.1    Suda, T.2
  • 13
    • 0036069819 scopus 로고    scopus 로고
    • Activated T cell death in vivo mediated by proapoptotic Bcl-2 family member Bim
    • DOI 10.1016/S1074-7613(02)00322-9
    • D.A. Hildeman, Y. Zhu, T.C. Mitchell, P. Bouillet, A. Strasser, J. Kappler, and P. Marrack Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim Immunity 16 2002 759 767 (Pubitemid 34786475)
    • (2002) Immunity , vol.16 , Issue.6 , pp. 759-767
    • Hildeman, D.A.1    Zhu, Y.2    Mitchell, T.C.3    Bouillet, P.4    Strasser, A.5    Kappler, J.6    Marrack, P.7
  • 16
    • 0029817246 scopus 로고    scopus 로고
    • T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions
    • B.L. Lohman, E.S. Razvi, and R.M. Welsh T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions J Virol 70 1996 8199 8203 (Pubitemid 26339138)
    • (1996) Journal of Virology , vol.70 , Issue.11 , pp. 8199-8203
    • Lohman, B.L.1    Razvi, E.S.2    Welsh, R.M.3
  • 17
    • 54949112078 scopus 로고    scopus 로고
    • Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells
    • A.S. Mohamood, D. Bargatze, Z. Xiao, C. Jie, H. Yagita, D. Ruben, J. Watson, S. Chakravarti, J.P. Schneck, and A.R. Hamad Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells PLoS One 3 2008 e3465
    • (2008) PLoS One , vol.3 , pp. 3465
    • Mohamood, A.S.1    Bargatze, D.2    Xiao, Z.3    Jie, C.4    Yagita, H.5    Ruben, D.6    Watson, J.7    Chakravarti, S.8    Schneck, J.P.9    Hamad, A.R.10
  • 20
    • 0033178741 scopus 로고    scopus 로고
    • Evidence that β cell death in the nonobese diabetic mouse is Fas independent
    • H.E. Thomas, R. Darwiche, J.A. Corbett, and T.W. Kay Evidence that beta cell death in the nonobese diabetic mouse is Fas independent J Immunol 163 1999 1562 1569 (Pubitemid 29352780)
    • (1999) Journal of Immunology , vol.163 , Issue.3 , pp. 1562-1569
    • Thomas, H.E.1    Darwiche, R.2    Corbett, J.A.3    Kay, T.W.H.4
  • 22
    • 0141993915 scopus 로고    scopus 로고
    • Effective destruction of Fas-deficient insulin-producing β cells in type 1 diabetes
    • DOI 10.1084/jem.20030698
    • I. Apostolou, Z. Hao, K. Rajewsky, and H. von Boehmer Effective destruction of Fas-deficient insulin-producing beta cells in type 1 diabetes J Exp Med 198 2003 1103 1106 (Pubitemid 37248625)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.7 , pp. 1103-1106
    • Apostolou, I.1    Hao, Z.2    Rajewsky, K.3    Von Boehmer, H.4
  • 25
    • 0034733584 scopus 로고    scopus 로고
    • Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations
    • DOI 10.1126/science.288.5475.2354
    • R.M. Siegel, J.K. Frederiksen, D.A. Zacharias, F.K. Chan, M. Johnson, D. Lynch, R.Y. Tsien, and M.J. Lenardo Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations Science 288 2000 2354 2357 (Pubitemid 30448157)
    • (2000) Science , vol.288 , Issue.5475 , pp. 2354-2357
    • Siegel, R.M.1    Frederiksen, J.K.2    Zacharias, D.A.3    Chan, F.K.-M.4    Johnson, M.5    Lynch, D.6    Tsien, R.Y.7    Lenardo, M.J.8
  • 26
    • 34547651331 scopus 로고    scopus 로고
    • Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically
    • DOI 10.2353/ajpath.2007.070148
    • A.S. Mohamood, M.L. Guler, Z. Xiao, D. Zheng, A. Hess, Y. Wang, H. Yagita, J.P. Schneck, and A.R. Hamad Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically Am J Pathol 171 2007 97 106 (Pubitemid 47339230)
    • (2007) American Journal of Pathology , vol.171 , Issue.1 , pp. 97-106
    • Mohamood, A.S.1    Guler, M.L.2    Xiao, Z.3    Zheng, D.4    Hess, A.5    Wang, Y.6    Yagita, H.7    Schneck, J.P.8    Hamad, A.R.A.9
  • 28
    • 2542449195 scopus 로고    scopus 로고
    • T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis
    • DOI 10.1084/jem.20032196
    • Z. Hao, B. Hampel, H. Yagita, and K. Rajewsky T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis J Exp Med 199 2004 1355 1365 (Pubitemid 38685727)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.10 , pp. 1355-1365
    • Hao, Z.1    Hampel, B.2    Yagita, H.3    Rajewsky, K.4
  • 30
    • 54949141219 scopus 로고    scopus 로고
    • Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression
    • T. Matsushita, K. Yanaba, J.D. Bouaziz, M. Fujimoto, and T.F. Tedder Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression J Clin Invest 118 2008 3420 3430
    • (2008) J Clin Invest , vol.118 , pp. 3420-3430
    • Matsushita, T.1    Yanaba, K.2    Bouaziz, J.D.3    Fujimoto, M.4    Tedder, T.F.5
  • 31
    • 0033579875 scopus 로고    scopus 로고
    • Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes
    • DOI 10.1084/jem.189.2.331
    • P. Hoglund, J. Mintern, C. Waltzinger, W. Heath, C. Benoist, and D. Mathis Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes J Exp Med 189 1999 331 339 (Pubitemid 29063254)
    • (1999) Journal of Experimental Medicine , vol.189 , Issue.2 , pp. 331-339
    • Hoglund, P.1    Mintern, J.2    Waltzinger, C.3    Heath, W.4    Benoist, C.5    Mathis, D.6
  • 32
    • 0027378612 scopus 로고
    • Following a diabetogenic T cell from genesis through pathogenesis
    • DOI 10.1016/0092-8674(93)90730-E
    • J.D. Katz, B. Wang, K. Haskins, C. Benoist, and D. Mathis Following a diabetogenic T cell from genesis through pathogenesis Cell 74 1993 1089 1100 (Pubitemid 23289465)
    • (1993) Cell , vol.74 , Issue.6 , pp. 1089-1100
    • Katz, J.D.1    Wang, B.2    Haskins, K.3    Benoist, C.4    Mathis, D.5
  • 33
    • 0037450740 scopus 로고    scopus 로고
    • Prevention of arthritis by interleukin 10-producing B cells
    • DOI 10.1084/jem.20021293
    • C. Mauri, D. Gray, N. Mushtaq, and M. Londei Prevention of arthritis by interleukin 10-producing B cells J Exp Med 197 2003 489 501 (Pubitemid 36278604)
    • (2003) Journal of Experimental Medicine , vol.197 , Issue.4 , pp. 489-501
    • Mauri, C.1    Gray, D.2    Mushtaq, N.3    Londei, M.4
  • 34
    • 0036197923 scopus 로고    scopus 로고
    • Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
    • DOI 10.1016/S1074-7613(02)00274-1
    • A. Mizoguchi, E. Mizoguchi, H. Takedatsu, R.S. Blumberg, and A.K. Bhan Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation Immunity 16 2002 219 230 (Pubitemid 34211962)
    • (2002) Immunity , vol.16 , Issue.2 , pp. 219-230
    • Mizoguchi, A.1    Mizoguchi, E.2    Takedatsu, H.3    Blumberg, R.S.4    Bhan, A.K.5
  • 35
    • 47249134619 scopus 로고    scopus 로고
    • Strategies for use of IL-10 or its antagonists in human disease
    • DOI 10.1111/j.1600-065X.2008.00635.x
    • A. O'Garra, F.J. Barrat, A.G. Castro, A. Vicari, and C. Hawrylowicz Strategies for use of IL-10 or its antagonists in human disease Immunol Rev 223 2008 114 131 (Pubitemid 351986180)
    • (2008) Immunological Reviews , vol.223 , Issue.1 , pp. 114-131
    • O'Garra, A.1    Barrat, F.J.2    Castro, A.G.3    Vicari, A.4    Hawrylowicz, C.5
  • 36
    • 0034659113 scopus 로고    scopus 로고
    • IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse
    • DOI 10.1006/cimm.2000.1658
    • B. Balasa, K. Van Gunst, N. Jung, J.D. Katz, and N. Sarvetnick IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse Cell Immunol 202 2000 97 102 (Pubitemid 30612716)
    • (2000) Cellular Immunology , vol.202 , Issue.2 , pp. 97-102
    • Balasa, B.1    Van Gunst, K.2    Jung, N.3    Katz, J.D.4    Sarvetnick, N.5
  • 37
    • 0028222756 scopus 로고
    • Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse
    • DOI 10.1006/clin.1994.1068
    • K.J. Pennline, E. Roque-Gaffney, and M. Monahan Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse Clin Immunol Immunopathol 71 1994 169 175 (Pubitemid 24147233)
    • (1994) Clinical Immunology and Immunopathology , vol.71 , Issue.2 , pp. 169-175
    • Pennline, K.J.1    Roque-Gaffney, E.R.2    Monahan, M.3
  • 38
    • 38849192507 scopus 로고    scopus 로고
    • Intravenous transfusion of BCR-activated B cells protects NOD mice from type 1 diabetes in an IL-10-dependent manner
    • S. Hussain, and T.L. Delovitch Intravenous transfusion of BCR-activated B cells protects NOD mice from type 1 diabetes in an IL-10-dependent manner J Immunol 179 2007 7225 7232
    • (2007) J Immunol , vol.179 , pp. 7225-7232
    • Hussain, S.1    Delovitch, T.L.2
  • 40
    • 0035863721 scopus 로고    scopus 로고
    • Th1 to Th2 cytokine shifts in nonobese diabetic mice: Sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation
    • D.V. Serreze, H.D. Chapman, C.M. Post, E.A. Johnson, W.L. Suarez-Pinzon, and A. Rabinovitch Th1 to Th2 cytokine shifts in nonobese diabetic mice: sometimes an outcome, rather than the cause, of diabetes resistance elicited by immunostimulation J Immunol 166 2001 1352 1359 (Pubitemid 32060298)
    • (2001) Journal of Immunology , vol.166 , Issue.2 , pp. 1352-1359
    • Serreze, D.V.1    Chapman, H.D.2    Post, C.M.3    Johnson, E.A.4    Suarez-Pinzon, W.L.5    Rabinovitch, A.6
  • 43
    • 33846085452 scopus 로고    scopus 로고
    • Cardiovascular disease risk in youth with diabetes mellitus
    • DOI 10.1007/s11154-006-9016-y, Special issue on Pediatric Diabetes
    • R.P. Wadwa Cardiovascular disease risk in youth with diabetes mellitus Rev Endocr Metab Disord 7 2006 197 204 (Pubitemid 46072643)
    • (2006) Reviews in Endocrine and Metabolic Disorders , vol.7 , Issue.3 , pp. 197-204
    • Wadwa, R.P.1
  • 44
    • 33845648357 scopus 로고    scopus 로고
    • Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies
    • DOI 10.1080/17402520600800721, PII H533716777715225
    • M. Ejrnaes, M.G. von Herrath, and U. Christen Cure of chronic viral infection and virus-induced type 1 diabetes by neutralizing antibodies Clin Dev Immunol 13 2006 337 347 (Pubitemid 44950049)
    • (2006) Clinical and Developmental Immunology , vol.13 , Issue.2-4 , pp. 337-347
    • Ejrnaes, M.1    Von Herrath, M.G.2    Christen, U.3
  • 45
    • 70249121089 scopus 로고    scopus 로고
    • The road not taken: A path to curing type 1 diabetes
    • M.J. Haller, M.A. Atkinson, and D.A. Schatz The road not taken: a path to curing type 1 diabetes Eur J Immunol 39 2009 2054 2058
    • (2009) Eur J Immunol , vol.39 , pp. 2054-2058
    • Haller, M.J.1    Atkinson, M.A.2    Schatz, D.A.3
  • 46
    • 77953392562 scopus 로고    scopus 로고
    • Combination therapies for type 1 diabetes: Why not now
    • M. von Herrath Combination therapies for type 1 diabetes: why not now Immunotherapy 2 2010 289 291
    • (2010) Immunotherapy , vol.2 , pp. 289-291
    • Von Herrath, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.