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Volumn 47, Issue 1-3, 2010, Pages 134-142

Analysis of gene profile, steady state proliferation and apoptosis of double-negative T cells in the periphery and gut epithelium provides new insights into the biological functions of the Fas pathway

Author keywords

Apoptosis; Double negative T cells; Fas; Fas ligand; Immunotherapy; Intraepithelial lymphocytes; Lymphoproliferation; Organ specific autoimmunity; Type 1 diabetes

Indexed keywords

FAS ANTIGEN; FAS LIGAND;

EID: 77953962836     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12026-009-8144-3     Document Type: Review
Times cited : (12)

References (43)
  • 1
    • 0141791068 scopus 로고    scopus 로고
    • Death receptor signaling and autoimmunity
    • DOI 10.1385/IR:27:2-3:499
    • RM Siegel J Muppidi M Roberts M Porter Z Wu 2003 Death receptor signaling and autoimmunity Immunol Res 27 499 512 10.1385/IR:27:2-3:499 1:CAS:528:DC%2BD3sXmvFyhsbk%3D 12857993 (Pubitemid 36995030)
    • (2003) Immunologic Research , vol.27 , Issue.2-3 , pp. 499-512
    • Siegel, R.M.1    Muppidi, J.2    Roberts, M.3    Porter, M.4    Wu, Z.5
  • 2
    • 0038171458 scopus 로고    scopus 로고
    • Activation-induced cell death in T cells
    • DOI 10.1034/j.1600-065X.2003.00051.x
    • DR Green N Droin M Pinkoski 2003 Activation-induced cell death in T cells Immunol Rev 193 70 81 10.1034/j.1600-065X.2003.00051.x 1:CAS:528: DC%2BD3sXkslemsLw%3D 12752672 (Pubitemid 36688041)
    • (2003) Immunological Reviews , vol.193 , pp. 70-81
    • Green, D.R.1    Droin, N.2    Pinkoski, M.3
  • 3
    • 0037833695 scopus 로고    scopus 로고
    • The role of CD95 in the regulation of peripheral T-cell apoptosis
    • DOI 10.1034/j.1600-065X.2003.00047.x
    • A Krueger SC Fas S Baumann PH Krammer 2003 The role of CD95 in the regulation of peripheral T-cell apoptosis Immunol Rev 193 58 69 10.1034/j.1600-065X.2003.00047.x 1:CAS:528:DC%2BD3sXkslemsL8%3D 12752671 (Pubitemid 36688040)
    • (2003) Immunological Reviews , vol.193 , pp. 58-69
    • Krueger, A.1    Fas, S.C.2    Baumann, S.3    Krammer, P.H.4
  • 4
    • 0028983657 scopus 로고
    • Cell autonomous Fas (CD95)/Fas ligand interaction mediates activation induced apoptosis in T cell hybridomas
    • 10.1038/373441a0 1:CAS:528:DyaK2MXjsFCjsL8%3D 7530336
    • T Brunner R Mog D LaFace N Yoo A Mahboubl F Echeverri S Martin W Force D Lynch C Ware D Green 1995 Cell autonomous Fas (CD95)/Fas ligand interaction mediates activation induced apoptosis in T cell hybridomas Nature 373 441 444 10.1038/373441a0 1:CAS:528:DyaK2MXjsFCjsL8%3D 7530336
    • (1995) Nature , vol.373 , pp. 441-444
    • Brunner, T.1    Mog, R.2    Laface, D.3    Yoo, N.4    Mahboubl, A.5    Echeverri, F.6    Martin, S.7    Force, W.8    Lynch, D.9    Ware, C.10    Green, D.11
  • 5
    • 0028795758 scopus 로고
    • Autocrine T cell suicide mediated by APO-1 (Fas/CD95)
    • 10.1038/373438a0 1:CAS:528:DyaK2MXjsFCjsL4%3D 7530335
    • J Dhein H Walczack C Baumler KM Debatin P Krammer 1995 Autocrine T cell suicide mediated by APO-1 (Fas/CD95) Nature 373 438 441 10.1038/373438a0 1:CAS:528:DyaK2MXjsFCjsL4%3D 7530335
    • (1995) Nature , vol.373 , pp. 438-441
    • Dhein, J.1    Walczack, H.2    Baumler, C.3    Debatin, K.M.4    Krammer, P.5
  • 6
    • 0028893078 scopus 로고
    • Fas (CD95)/FasL interactions required for programmed cell death after T cell activation
    • 10.1038/373444a0 1:CAS:528:DyaK2MXjsFCjsLw%3D 7530337
    • S Ju D Panks H Cul R Ettingor M Elkhatib D Sherr B Stanger A Marshak-Rothstein 1995 Fas (CD95)/FasL interactions required for programmed cell death after T cell activation Nature 373 444 448 10.1038/373444a0 1:CAS:528:DyaK2MXjsFCjsLw%3D 7530337
    • (1995) Nature , vol.373 , pp. 444-448
    • Ju, S.1    Panks, D.2    Cul, H.3    Ettingor, R.4    Elkhatib, M.5    Sherr, D.6    Stanger, B.7    Marshak-Rothstein, A.8
  • 7
    • 0028980902 scopus 로고
    • Fas and Fas ligand: Lpr and gld mutations
    • 10.1016/0167-5699(95)80069-7 1:CAS:528:DyaK2MXjsVyjtrc%3D 7533498
    • S Nagata T Suda 1995 Fas and Fas ligand: lpr and gld mutations Immunol Today 16 39 43 10.1016/0167-5699(95)80069-7 1:CAS:528:DyaK2MXjsVyjtrc%3D 7533498
    • (1995) Immunol Today , vol.16 , pp. 39-43
    • Nagata, S.1    Suda, T.2
  • 8
    • 0024209920 scopus 로고
    • - T cells of lpr mice
    • DOI 10.1084/jem.168.6.2221
    • BL Kotzin SK Babcock LR Herron 1988 Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice J Exp Med 168 2221 2229 10.1084/jem.168.6.2221 1:STN:280:DyaL1M%2Fmslyhug%3D%3D 3264325 (Pubitemid 19020901)
    • (1988) Journal of Experimental Medicine , vol.168 , Issue.6 , pp. 2221-2229
    • Kotzin, B.L.1    Babcock, S.K.2    Herron, L.R.3
  • 9
    • 0024331976 scopus 로고
    • + and abnormal lpr and gld cell populations
    • DOI 10.1084/jem.170.6.1869
    • PA Singer RS Balderas RJ McEvilly M Bobardt AN Theofilopoulos 1989 Tolerance-related V beta clonal deletions in normal CD4-8-, TCR-alpha/beta+ and abnormal lpr and gld cell populations J Exp Med 170 1869 1877 10.1084/jem.170.6.1869 1:CAS:528:DyaK3cXnsFWgtA%3D%3D 2511266 (Pubitemid 20010070)
    • (1989) Journal of Experimental Medicine , vol.170 , Issue.6 , pp. 1869-1877
    • Singer, P.A.1    Balderas, R.S.2    McEvilly, R.J.3    Bobardt, M.4    Theofilopoulos, A.N.5
  • 10
    • 0025214415 scopus 로고
    • Altered expression of self-reactive T cell receptor v beta regions in autoimmune mice
    • 1:CAS:528:DyaK3cXitFCqu7o%3D 1690237
    • JD Mountz TM Smith KS Toth 1990 Altered expression of self-reactive T cell receptor V beta regions in autoimmune mice J Immunol 144 2159 2166 1:CAS:528:DyaK3cXitFCqu7o%3D 1690237
    • (1990) J Immunol , vol.144 , pp. 2159-2166
    • Mountz, J.D.1    Smith, T.M.2    Toth, K.S.3
  • 11
    • 0026671268 scopus 로고
    • Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice
    • 10.1084/jem.176.4.1063 1:CAS:528:DyaK38Xls12gsbw%3D 1402652
    • T Zhou H Bluethmann J Zhang CK Edwards JD Mountz 1992 Defective maintenance of T cell tolerance to a superantigen in MRL-lpr/lpr mice J Exp Med 176 1063 1072 10.1084/jem.176.4.1063 1:CAS:528:DyaK38Xls12gsbw%3D 1402652
    • (1992) J Exp Med , vol.176 , pp. 1063-1072
    • Zhou, T.1    Bluethmann, H.2    Zhang, J.3    Edwards, C.K.4    Mountz, J.D.5
  • 12
    • 0028206753 scopus 로고
    • A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice
    • 10.1002/eji.1830240526 1:CAS:528:DyaK2cXktVOis7c%3D 8181528
    • I Gillette-Ferguson CL Sidman 1994 A specific intercellular pathway of apoptotic cell death is defective in the mature peripheral T cells of autoimmune lpr and gld mice Eur J Immunol 24 1181 1185 10.1002/eji.1830240526 1:CAS:528:DyaK2cXktVOis7c%3D 8181528
    • (1994) Eur J Immunol , vol.24 , pp. 1181-1185
    • Gillette-Ferguson, I.1    Sidman, C.L.2
  • 13
    • 0029097729 scopus 로고
    • Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo
    • 10.1093/intimm/7.9.1451 1:CAS:528:DyaK2MXot1SgsLs%3D 7495753
    • RJ Mogil L Radvanyi R Gonzalez-Quintial R Miller G Mills AN Theofilopoulos DR Green 1995 Fas (CD95) participates in peripheral T cell deletion and associated apoptosis in vivo Int Immunol 7 1451 1458 10.1093/intimm/7.9.1451 1:CAS:528:DyaK2MXot1SgsLs%3D 7495753
    • (1995) Int Immunol , vol.7 , pp. 1451-1458
    • Mogil, R.J.1    Radvanyi, L.2    Gonzalez-Quintial, R.3    Miller, R.4    Mills, G.5    Theofilopoulos, A.N.6    Green, D.R.7
  • 14
    • 0036069819 scopus 로고    scopus 로고
    • Activated T cell death in vivo mediated by proapoptotic Bcl-2 family member Bim
    • DOI 10.1016/S1074-7613(02)00322-9
    • DA Hildeman Y Zhu TC Mitchell P Bouillet A Strasser J Kappler P Marrack 2002 Activated T cell death in vivo mediated by proapoptotic bcl-2 family member bim Immunity 16 759 767 10.1016/S1074-7613(02)00322-9 1:CAS:528: DC%2BD38XltF2gtb0%3D 12121658 (Pubitemid 34786475)
    • (2002) Immunity , vol.16 , Issue.6 , pp. 759-767
    • Hildeman, D.A.1    Zhu, Y.2    Mitchell, T.C.3    Bouillet, P.4    Strasser, A.5    Kappler, J.6    Marrack, P.7
  • 15
    • 0028179019 scopus 로고
    • A single injection of Staphylococcus aureus enterotoxin B reduces autoimmunity in MRL/lpr mice
    • 10.1006/clin.1994.1069 1:CAS:528:DyaK2cXlsVyqu7Y%3D 8181186
    • JA Gonzalo R Tarazona HJ Schuurman F Uytdehaag G Wick C Martinez G Kroemer 1994 A single injection of Staphylococcus aureus enterotoxin B reduces autoimmunity in MRL/lpr mice Clin Immunol Immunopathol 71 176 182 10.1006/clin.1994.1069 1:CAS:528:DyaK2cXlsVyqu7Y%3D 8181186
    • (1994) Clin Immunol Immunopathol , vol.71 , pp. 176-182
    • Gonzalo, J.A.1    Tarazona, R.2    Schuurman, H.J.3    Uytdehaag, F.4    Wick, G.5    Martinez, C.6    Kroemer, G.7
  • 16
    • 0029817246 scopus 로고    scopus 로고
    • T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions
    • 1:CAS:528:DyaK28XmtlSlsrc%3D 8892953
    • BL Lohman ES Razvi RM Welsh 1996 T-lymphocyte downregulation after acute viral infection is not dependent on CD95 (Fas) receptor-ligand interactions J Virol 70 8199 8203 1:CAS:528:DyaK28XmtlSlsrc%3D 8892953
    • (1996) J Virol , vol.70 , pp. 8199-8203
    • Lohman, B.L.1    Razvi, E.S.2    Welsh, R.M.3
  • 17
    • 0029901780 scopus 로고    scopus 로고
    • Mechanisms of peripheral T cell deletion: Anergized T cells are Fas resistant but undergo proliferation-associated apoptosis
    • DOI 10.1002/eji.1830260709
    • T Miethke R Vabulas R Bittlingmaier K Heeg H Wagner 1996 Mechanisms of peripheral T cell deletion: anergized T cells are Fas resistant but undergo proliferation-associated apoptosis Eur J Immunol 26 1459 1467 10.1002/eji.1830260709 1:CAS:528:DyaK28Xkt1ChtLo%3D 8766547 (Pubitemid 26229989)
    • (1996) European Journal of Immunology , vol.26 , Issue.7 , pp. 1459-1467
    • Miethke, T.1    Vabulas, R.2    Bittlingmaier, R.3    Heeg, K.4    Wagner, H.5
  • 18
    • 67649884532 scopus 로고    scopus 로고
    • CD95, BIM and T cell homeostasis
    • 10.1038/nri2570 1:CAS:528:DC%2BD1MXnsVylur8%3D 19543226
    • P Bouillet LA O'Reilly 2009 CD95, BIM and T cell homeostasis Nat Rev Immunol 9 514 519 10.1038/nri2570 1:CAS:528:DC%2BD1MXnsVylur8%3D 19543226
    • (2009) Nat Rev Immunol , vol.9 , pp. 514-519
    • Bouillet, P.1    O'Reilly, L.A.2
  • 20
    • 0031405867 scopus 로고    scopus 로고
    • + T cells
    • DOI 10.1016/S1074-7613(00)80406-9
    • CA Chambers TJ Sullivan JP Allison 1997 Lymphoproliferation in CTLA-4-deficient mice is mediated by costimulation-dependent activation of CD4+ T cells Immunity 7 885 895 10.1016/S1074-7613(00)80406-9 1:CAS:528: DyaK1cXjsFaqsQ%3D%3D 9430233 (Pubitemid 28064901)
    • (1997) Immunity , vol.7 , Issue.6 , pp. 885-895
    • Chambers, C.A.1    Sullivan, T.J.2    Allison, J.P.3
  • 21
    • 0026043866 scopus 로고
    • Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: Potential model for thymic education
    • 10.1073/pnas.88.13.5528 1:STN:280:DyaK3M3ovVCqtQ%3D%3D 2062835
    • VL Godfrey JE Wilkinson EM Rinchik LB Russell 1991 Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education Proc Natl Acad Sci USA 88 5528 5532 10.1073/pnas.88.13.5528 1:STN:280:DyaK3M3ovVCqtQ%3D%3D 2062835
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 5528-5532
    • Godfrey, V.L.1    Wilkinson, J.E.2    Rinchik, E.M.3    Russell, L.B.4
  • 23
    • 0031253737 scopus 로고    scopus 로고
    • Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis
    • 1:CAS:528:DyaK2sXmtlOjtrw%3D 9317104
    • H Waldner RA Sobel E Howard VK Kuchroo 1997 Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis J Immunol 159 3100 3103 1:CAS:528:DyaK2sXmtlOjtrw%3D 9317104
    • (1997) J Immunol , vol.159 , pp. 3100-3103
    • Waldner, H.1    Sobel, R.A.2    Howard, E.3    Kuchroo, V.K.4
  • 24
    • 34547651331 scopus 로고    scopus 로고
    • Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically
    • DOI 10.2353/ajpath.2007.070148
    • AS Mohamood ML Guler Z Xiao D Zheng A Hess Y Wang H Yagita JP Schneck AR Hamad 2007 Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically Am J Patho l 171 97 106 10.2353/ajpath.2007.070148 1:CAS:528:DC%2BD2sXosValsrY%3D (Pubitemid 47339230)
    • (2007) American Journal of Pathology , vol.171 , Issue.1 , pp. 97-106
    • Mohamood, A.S.1    Guler, M.L.2    Xiao, Z.3    Zheng, D.4    Hess, A.5    Wang, Y.6    Yagita, H.7    Schneck, J.P.8    Hamad, A.R.A.9
  • 25
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • 10.1126/science.286.5445.1735 1:CAS:528:DyaK1MXnsl2nsLo%3D 10576740
    • P Bouillet D Metcalf DC Huang DM Tarlinton TW Kay F Kontgen JM Adams A Strasser 1999 Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity Science 286 1735 1738 10.1126/science.286.5445.1735 1:CAS:528:DyaK1MXnsl2nsLo%3D 10576740
    • (1999) Science , vol.286 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.3    Tarlinton, D.M.4    Kay, T.W.5    Kontgen, F.6    Adams, J.M.7    Strasser, A.8
  • 26
    • 0042430410 scopus 로고    scopus 로고
    • B220+ double-negative T cells suppress polyclonal T cell activation by a Fas-independent mechanism that involves inhibition of IL-2 production
    • 1:CAS:528:DC%2BD3sXmsVOrt7c%3D 12928389
    • AR Hamad AS Mohamood CJ Trujillo CT Huang E Yuan JP Schneck 2003 B220+ double-negative T cells suppress polyclonal T cell activation by a Fas-independent mechanism that involves inhibition of IL-2 production J Immunol 171 2421 2426 1:CAS:528:DC%2BD3sXmsVOrt7c%3D 12928389
    • (2003) J Immunol , vol.171 , pp. 2421-2426
    • Hamad, A.R.1    Mohamood, A.S.2    Trujillo, C.J.3    Huang, C.T.4    Yuan, E.5    Schneck, J.P.6
  • 27
    • 54949112078 scopus 로고    scopus 로고
    • Fas-mediated apoptosis regulates the composition of peripheral alphabet a T cell repertoire by constitutively purging out double negative T cells
    • 10.1371/journal.pone.0003465 18941614
    • AS Mohamood D Bargatze Z Xiao C Jie H Yagita D Ruben J Watson S Chakravarti JP Schneck AR Hamad 2008 Fas-mediated apoptosis regulates the composition of peripheral alphabet a T cell repertoire by constitutively purging out double negative T cells PLoS ONE 3 e3465 10.1371/journal.pone.0003465 18941614
    • (2008) PLoS ONE , vol.3 , pp. 3465
    • Mohamood, A.S.1    Bargatze, D.2    Xiao, Z.3    Jie, C.4    Yagita, H.5    Ruben, D.6    Watson, J.7    Chakravarti, S.8    Schneck, J.P.9    Hamad, A.R.10
  • 28
    • 0030065003 scopus 로고    scopus 로고
    • The role of syndecan-1 in malignancies
    • 10.3109/07853899608999076 1:CAS:528:DyaK28XjtVGku7g%3D 8932508
    • P Inki M Jalkanen 1996 The role of syndecan-1 in malignancies Ann Med 28 63 67 10.3109/07853899608999076 1:CAS:528:DyaK28XjtVGku7g%3D 8932508
    • (1996) Ann Med , vol.28 , pp. 63-67
    • Inki, P.1    Jalkanen, M.2
  • 29
    • 7044231033 scopus 로고    scopus 로고
    • Biological role of Ep-CAM in the physical interaction between epithelial cells and lymphocytes in intestinal epithelium
    • DOI 10.1016/j.clim.2004.08.013, PII S1521661604002670
    • T Nochi Y Yuki K Terahara A Hino J Kunisawa MN Kweon T Yamaguchi H Kiyono 2004 Biological role of Ep-CAM in the physical interaction between epithelial cells and lymphocytes in intestinal epithelium Clin Immunol 113 326 339 10.1016/j.clim.2004.08.013 1:CAS:528:DC%2BD2cXovVKltL8%3D 15507398 (Pubitemid 39422612)
    • (2004) Clinical Immunology , vol.113 , Issue.3 , pp. 326-339
    • Nochi, T.1    Yuki, Y.2    Terahara, K.3    Hino, A.4    Kunisawa, J.5    Kweon, M.-N.6    Yamaguchi, T.7    Kiyono, H.8
  • 30
    • 0028577357 scopus 로고
    • Desmosomes and cytoskeletal architecture in epithelial differentiation: Cell type-specific plaque components and intermediate filament anchorage
    • 1:CAS:528:DyaK2MXktVWgu70%3D 7720719
    • A Schmidt HW Heid S Schafer UA Nuber R Zimbelmann WW Franke 1994 Desmosomes and cytoskeletal architecture in epithelial differentiation: cell type-specific plaque components and intermediate filament anchorage Eur J Cell Biol 65 229 245 1:CAS:528:DyaK2MXktVWgu70%3D 7720719
    • (1994) Eur J Cell Biol , vol.65 , pp. 229-245
    • Schmidt, A.1    Heid, H.W.2    Schafer, S.3    Nuber, U.A.4    Zimbelmann, R.5    Franke, W.W.6
  • 31
    • 0034525054 scopus 로고    scopus 로고
    • Molecular diversity of plaques of epithelial-adhering junctions
    • 1:CAS:528:DC%2BD3MXntVCgtQ%3D%3D 11193570
    • CM Borrmann C Mertens A Schmidt L Langbein C Kuhn WW Franke 2000 Molecular diversity of plaques of epithelial-adhering junctions Ann N Y Acad Sci 915 144 150 1:CAS:528:DC%2BD3MXntVCgtQ%3D%3D 11193570
    • (2000) Ann N y Acad Sci , vol.915 , pp. 144-150
    • Borrmann, C.M.1    Mertens, C.2    Schmidt, A.3    Langbein, L.4    Kuhn, C.5    Franke, W.W.6
  • 32
    • 18844429991 scopus 로고    scopus 로고
    • Intraepithelial lymphocytes express junctional molecules in murine small intestine
    • DOI 10.1016/j.bbrc.2005.04.025, PII S0006291X05007722
    • K Inagaki-Ohara A Sawaguchi T Suganuma G Matsuzaki Y Nawa 2005 Intraepithelial lymphocytes express junctional molecules in murine small intestine Biochem Biophys Res Commun 331 977 983 10.1016/j.bbrc.2005.04.025 1:CAS:528:DC%2BD2MXjvFemtLo%3D 15882974 (Pubitemid 40692457)
    • (2005) Biochemical and Biophysical Research Communications , vol.331 , Issue.4 , pp. 977-983
    • Inagaki-Ohara, K.1    Sawaguchi, A.2    Suganuma, T.3    Matsuzaki, G.4    Nawa, Y.5
  • 33
    • 0034851982 scopus 로고    scopus 로고
    • Galectins as modulators of cell adhesion
    • DOI 10.1016/S0300-9084(01)01289-5
    • RC Hughes 2001 Galectins as modulators of cell adhesion Biochimie 83 667 676 10.1016/S0300-9084(01)01289-5 1:STN:280:DC%2BD3MvnvVyisA%3D%3D 11522396 (Pubitemid 32821230)
    • (2001) Biochimie , vol.83 , Issue.7 , pp. 667-676
    • Hughes, R.C.1
  • 34
    • 0026338495 scopus 로고
    • Cell cycle analysis and DNA aneuploidy in autoimmune mice homozygous for the lpr and gld mutations
    • 1:STN:280:DyaK38%2FptFOhtA%3D%3D 1753097
    • VS Prasad CL Sidman 1991 Cell cycle analysis and DNA aneuploidy in autoimmune mice homozygous for the lpr and gld mutations J Immunol 147 4200 4206 1:STN:280:DyaK38%2FptFOhtA%3D%3D 1753097
    • (1991) J Immunol , vol.147 , pp. 4200-4206
    • Prasad, V.S.1    Sidman, C.L.2
  • 35
    • 0037376153 scopus 로고    scopus 로고
    • Compartmentalization of Fas and Fas ligand may prevent auto- or paracrine apoptosis in epithelial cells
    • DOI 10.1016/S0014-4827(02)00056-3
    • KH Tan W Hunziker 2003 Compartmentalization of Fas and Fas ligand may prevent auto- or paracrine apoptosis in epithelial cells Exp Cell Res 284 283 290 10.1016/S0014-4827(02)00056-3 1:CAS:528:DC%2BD3sXitVylu7s%3D 12651160 (Pubitemid 36324535)
    • (2003) Experimental Cell Research , vol.284 , Issue.2 , pp. 283-290
    • Tan, K.H.1    Hunziker, W.2
  • 36
    • 34848894301 scopus 로고    scopus 로고
    • Rational development of antigen-specific therapies for type 1 diabetes
    • 17713020
    • G Fousteri D Bresson M von Herrath 2007 Rational development of antigen-specific therapies for type 1 diabetes Adv Exp Med Biol 601 313 319 17713020
    • (2007) Adv Exp Med Biol , vol.601 , pp. 313-319
    • Fousteri, G.1    Bresson, D.2    Von Herrath, M.3
  • 38
    • 0025875259 scopus 로고
    • Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
    • 10.1146/annurev.iy.09.040191.001331 1:CAS:528:DyaK3MXmt12kurY%3D 1910678
    • P Cohen R Eisenberg 1991 Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease Annu Rev Immunol 9 243 269 10.1146/annurev.iy.09.040191.001331 1:CAS:528:DyaK3MXmt12kurY%3D 1910678
    • (1991) Annu Rev Immunol , vol.9 , pp. 243-269
    • Cohen, P.1    Eisenberg, R.2
  • 39
    • 0034162513 scopus 로고    scopus 로고
    • Significant role for Fas in the pathogenesis of autoimmune diabetes
    • 1:CAS:528:DC%2BD3cXhsVKhtrg%3D 10679090
    • X Su Q Hu JM Kristan C Costa Y Shen D Gero LA Matis Y Wang 2000 Significant role for Fas in the pathogenesis of autoimmune diabetes J Immunol 164 2523 2532 1:CAS:528:DC%2BD3cXhsVKhtrg%3D 10679090
    • (2000) J Immunol , vol.164 , pp. 2523-2532
    • Su, X.1    Hu, Q.2    Kristan, J.M.3    Costa, C.4    Shen, Y.5    Gero, D.6    Matis, L.A.7    Wang, Y.8
  • 41
    • 0032780419 scopus 로고    scopus 로고
    • Structure and function of Fas/Fas ligand
    • 1:CAS:528:DyaK1MXlvVCmtbs%3D 10626245
    • JR Orlinick AK Vaishnaw KB Elkon 1999 Structure and function of Fas/Fas ligand Int Rev Immunol 18 293 308 1:CAS:528:DyaK1MXlvVCmtbs%3D 10626245
    • (1999) Int Rev Immunol , vol.18 , pp. 293-308
    • Orlinick, J.R.1    Vaishnaw, A.K.2    Elkon, K.B.3
  • 43
    • 0141993915 scopus 로고    scopus 로고
    • Effective destruction of Fas-deficient insulin-producing β cells in type 1 diabetes
    • DOI 10.1084/jem.20030698
    • I Apostolou Z Hao K Rajewsky H von Boehmer 2003 Effective destruction of Fas-deficient insulin-producing beta cells in type 1 diabetes J Exp Med 198 1103 1106 10.1084/jem.20030698 1:CAS:528:DC%2BD3sXotVWgs7Y%3D 14530378 (Pubitemid 37248625)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.7 , pp. 1103-1106
    • Apostolou, I.1    Hao, Z.2    Rajewsky, K.3    Von Boehmer, H.4


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