Thrombospondin-1 and angiotensin II inhibit soluble guanylyl cyclase through an increase in intracellular calcium concentration

Biochemistry

Volumn 50, Issue 36, 2011, Pages 7787-7799

  Ramanathan, Saumya ^a   Mazzalupo, Stacy ^b   Boitano, Scott ^c   Montfort, William R ^b  

^a University of Arizona   (United States)

^b University of Arizona   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; C-TERMINAL FRAGMENTS; CELL SURFACE RECEPTORS; CELL-FREE; CYTOSOLIC CALCIUM; DIGITAL IMAGING; GUANYLYL CYCLASE; INTRACELLULAR CALCIUM CONCENTRATION; KINASE INHIBITORS; LIVE CELL; LYSATES; MATRICELLULAR PROTEIN; SOLUBLE GUANYLYL CYCLASE (SGC); STAUROSPORINES; T CELLS; VASORELAXATION;

CELLS; ENZYME INHIBITION; FLOW CYTOMETRY; LEAD OXIDE; NITRIC OXIDE; PHOSPHORYLATION; PLANTS (BOTANY); PROTEINS;

CALCIUM;

4 AMINO 5 CYCLOPROPYL 2 [1 (2 FLUOROBENZYL) 1H PYRAZOLO[3,4 B]PYRIDIN 3 YL]PYRIMIDINE; ANGIOTENSIN II; CD47 ANTIGEN; CYCLIC GMP; LIFICIGUAT; NITRIC OXIDE; PROTEIN KINASE C; STAUROSPORINE; THROMBOSPONDIN 1;

ALLOSTERISM; ARTICLE; CALCIUM CELL LEVEL; CELL LYSATE; CONCENTRATION PROCESS; CONTROLLED STUDY; DRUG INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYPERTENSION; IMMUNOPRECIPITATION; LEUKEMIA CELL LINE; MICROSCOPY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; VASODILATATION;

ANGIOTENSIN II; ANTIGENS, CD47; CALCIUM; CELLS, CULTURED; FLOW CYTOMETRY; GUANYLATE CYCLASE; HUMANS; JURKAT CELLS; KINETICS; NITRIC OXIDE; PHOSPHORYLATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; THROMBOSPONDIN 1; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 80052479984     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201060c     Document Type: Article

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