Rapid nitric oxide-induced desensitization of the cGMP response is caused by increased activity of phosphodiesterase type 5 paralleled by phosphorylation of the enzyme
Mullershausen F, Russwurm M, Thompson WJ, et al. Rapid nitric oxide-induced desensitization of the cGMP response is caused by increased activity of phosphodiesterase type 5 paralleled by phosphorylation of the enzyme. J Cell Biol. 2001;155:271-278.
YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase
Wu CC, Ko FN, Kuo SC, et al. YC-1 inhibited human platelet aggregation through NO-independent activation of soluble guanylate cyclase. Br J Pharmacol. 1995;116:1973-1978.
Acute blood pressure effects of YC-1-induced activation of soluble guanylyl cyclase in normotensive and hypertensive rats
Rothermund L, Friebe A, Paul M, et al. Acute blood pressure effects of YC-1-induced activation of soluble guanylyl cyclase in normotensive and hypertensive rats. Br J Pharmacol. 2000;130:205-208.
YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets
Friebe A, Mullershausen F, Smolenski A, et al. YC-1 potentiates nitric oxide- and carbon monoxide-induced cyclic GMP effects in human platelets. Mol Pharmacol. 1998;54:962-967.
Inhibition of deactivation of NO-sensitive guanylyl cyclase accounts for the sensitizing effect of YC-1
Russwurm M, Mergia E, Mullershausen F, et al. Inhibition of deactivation of NO-sensitive guanylyl cyclase accounts for the sensitizing effect of YC-1. J Biol Chem. 2002;277:24883-24888.
Direct activation of PDE5 by cGMP: Long-term effects within NO/cGMP signaling
Mullershausen F, Friebe A, Feil R, et al. Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling. J Cell Biol. 2003; 160:719-727.